HU185518B - Process for preparing 2-/e/-phenyl-methylene-cycloheptan-1-one-/e/-oxime - Google Patents

Process for preparing 2-/e/-phenyl-methylene-cycloheptan-1-one-/e/-oxime Download PDF

Info

Publication number
HU185518B
HU185518B HU82997A HU99782A HU185518B HU 185518 B HU185518 B HU 185518B HU 82997 A HU82997 A HU 82997A HU 99782 A HU99782 A HU 99782A HU 185518 B HU185518 B HU 185518B
Authority
HU
Hungary
Prior art keywords
cycloheptan
reaction
phenylmethylene
formula
oxime
Prior art date
Application number
HU82997A
Other languages
English (en)
Hungarian (hu)
Inventor
Zoltan Budai
Laszlone Lay
Tibor Mezei
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Priority to HU82997A priority Critical patent/HU185518B/hu
Priority to IL68079A priority patent/IL68079A/xx
Priority to BE1/10748A priority patent/BE896279A/fr
Priority to ES521096A priority patent/ES8405366A1/es
Priority to FI831087A priority patent/FI831087L/fi
Priority to SE8301817A priority patent/SE8301817L/xx
Priority to DK148783A priority patent/DK148783A/da
Priority to GB08308956A priority patent/GB2117773B/en
Priority to CH179183A priority patent/CH656121B/de
Priority to FR8305314A priority patent/FR2524464B1/fr
Priority to JP58056809A priority patent/JPS58208262A/ja
Priority to DE19833311895 priority patent/DE3311895A1/de
Priority to CA000425105A priority patent/CA1210027A/en
Priority to NL8301175A priority patent/NL8301175A/nl
Priority to AT0116983A priority patent/AT384423B/de
Priority to YU00776/83A priority patent/YU77683A/xx
Priority to IT20428/83A priority patent/IT1194184B/it
Priority to DD83249465A priority patent/DD209619A5/de
Publication of HU185518B publication Critical patent/HU185518B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/04—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/04—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes
    • C07C249/08—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes by reaction of hydroxylamines with carbonyl compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C1/00—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C239/00—Compounds containing nitrogen-to-halogen bonds; Hydroxylamino compounds or ethers or esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32—Oximes
    • C07C251/34—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C251/44—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atom of at least one of the oxyimino groups being part of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

DIE ERFINDUNG BETRIFFT EIN VERFAHREN ZUR HERSTELLUNG VON 2-(E)-PHENYLMETHYLEN-CYCLOHEPTAN-I-ON-(E)-OXIM DER FORMEL (I) IN VON ANDEREN ISOMEREN FREIEM ZUSTAND DURCH UMSETZUNG VON 2-(E)-PHENYLMETHYLEN-CYCLOHEPTAN-I-ON DER FORMEL (II) MIT AUS EINEM HYDROXYLAMINSALZ IN GEGENWART EINER BASE "IN SITU" GEBILDETEM HYDROXYLAMIN, DAS DADURCH GEKENNZEICHNET IST, DASS MAN DIE UMSETZUNG IN EINEM WAESSRIGEN UND/ODER MIT WASSER UNBEGRENZT VERMISCHBAREN NIEDEREN ALIPHATISCHEN ALKOHOLISCHEN MEDIUM DURCHFUEHRT UND NACH ABLAUF DER REAKTION DEN ALKOHOLGEHALT DES MEDIUMS AUF 40 BIS 60 % EINSTELLT UND DAS 2-(E)-PHENYLMETHYLEN-CYCLOHEPTAN-I-ON-(E)-OXIN IN AN SICH BEKANNTER WEISE ISOLIERT. DER VORTEIL DES VERFAHRENS LIEGT DARIN, DASS DIE GEWUENSCHTE VERBINDUNG DER FORMEL I IN ISOMERFREIEM ZUSTAND UND MIT SEHR GUTER AUSBEUTE HERSTELLBAR IST. DIE VERBINDUNG DER FORMEL I IST EIN BEKANNTES UNDWERTVOLLES PHARMAZEUTISCHES ZWISCHENPRODUKT.
HU82997A 1982-04-01 1982-04-01 Process for preparing 2-/e/-phenyl-methylene-cycloheptan-1-one-/e/-oxime HU185518B (en)

Priority Applications (18)

Application Number Priority Date Filing Date Title
HU82997A HU185518B (en) 1982-04-01 1982-04-01 Process for preparing 2-/e/-phenyl-methylene-cycloheptan-1-one-/e/-oxime
IL68079A IL68079A (en) 1982-04-01 1983-03-07 Preparation of 2-(e)-phenyl-methylenecycloheptan-1-one-(e)-oxime
BE1/10748A BE896279A (fr) 1982-04-01 1983-03-28 Procede de preparation de la 2- (e) -phenylmethylene-cycloheptan-1-one- (e) -oxime
ES521096A ES8405366A1 (es) 1982-04-01 1983-03-29 Procedimiento de preparacion de 2-(e)-fenilmetilenocicloheptan-1-ona-(e)-oxima.
FI831087A FI831087L (fi) 1982-04-01 1983-03-30 Foerfarande foer framstaellning av 2-(e)-fenylmetylencykloheptan-1-on-(e)-oxim
SE8301817A SE8301817L (sv) 1982-04-01 1983-03-30 Forfarande for framsellning av 2-(e)-fenylmetylencykloheptan-1-on-(e)-oxim
DK148783A DK148783A (da) 1982-04-01 1983-03-30 Fremgangsmaade til fremstilling af 2-(e)-phenylmethylencycloheptan-1-on-(e)-oxim
GB08308956A GB2117773B (en) 1982-04-01 1983-03-31 Process for the preparation of 2-/e/-phenylmethylene-cycloheptan-1-one-/e/-oxime
CH179183A CH656121B (de) 1982-04-01 1983-03-31
FR8305314A FR2524464B1 (fr) 1982-04-01 1983-03-31 Procede de preparation de la 2-(e)-phephenylmethylene-cycloheptan-1-one-(e)-oxime
JP58056809A JPS58208262A (ja) 1982-04-01 1983-03-31 ２−（ｅ）−フエニルメチレンシクロヘプタン−１−オン−（ｅ）−オキシムの製造方法
DE19833311895 DE3311895A1 (de) 1982-04-01 1983-03-31 2-(e)-(benzal)-cycloheptan-1-((e)-oxim), verfahren zu seiner herstellung und dieses enthaltende arzneimittel
CA000425105A CA1210027A (en) 1982-04-01 1983-03-31 Process for the preparation of 2-/e/phenyl- methylenecycloheptan-1-one-/e/-oxime
NL8301175A NL8301175A (nl) 1982-04-01 1983-04-01 Werkwijze voor de bereiding van 2-(e)-fenylmethyleencycloheptan-1-on-(e)-oxim.
AT0116983A AT384423B (de) 1982-04-01 1983-04-01 Verfahren zur herstellung von 2-(e)-phenylmethylen-cycloheptan-1-on-(e)-oxim
YU00776/83A YU77683A (en) 1982-04-01 1983-04-01 Process for obtaining 2-(e-)-phenylmethlyene-cycloheptne-1-one-(e)-oxime
IT20428/83A IT1194184B (it) 1982-04-01 1983-04-01 Procedimento per la preparazione della 2-(e)-fenilmetilen-cicloeptan-1-one-(e)-ossima
DD83249465A DD209619A5 (de) 1982-04-01 1983-04-04 Verfahren zur herstellung von 2-(e)-phenylmethylen-cycloheptan-1-on-(e)-oxim

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU82997A HU185518B (en) 1982-04-01 1982-04-01 Process for preparing 2-/e/-phenyl-methylene-cycloheptan-1-one-/e/-oxime

Publications (1)

Publication Number Publication Date
HU185518B true HU185518B (en) 1985-02-28

Family

ID=10952372

Family Applications (1)

Application Number Title Priority Date Filing Date
HU82997A HU185518B (en) 1982-04-01 1982-04-01 Process for preparing 2-/e/-phenyl-methylene-cycloheptan-1-one-/e/-oxime

Country Status (18)

Country Link
JP (1) JPS58208262A (de)
AT (1) AT384423B (de)
BE (1) BE896279A (de)
CA (1) CA1210027A (de)
CH (1) CH656121B (de)
DD (1) DD209619A5 (de)
DE (1) DE3311895A1 (de)
DK (1) DK148783A (de)
ES (1) ES8405366A1 (de)
FI (1) FI831087L (de)
FR (1) FR2524464B1 (de)
GB (1) GB2117773B (de)
HU (1) HU185518B (de)
IL (1) IL68079A (de)
IT (1) IT1194184B (de)
NL (1) NL8301175A (de)
SE (1) SE8301817L (de)
YU (1) YU77683A (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2279757C2 (ru) * 2004-09-13 2006-07-10 "Центр Разработки Нефтедобывающего Оборудования" ("Црно") Способ управления вентильным электродвигателем и устройство для его осуществления

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4083978A (en) * 1976-01-27 1978-04-11 Egyt Gyogyszervegyeszeti Gyar Oxime ethers

Also Published As

Publication number Publication date
FI831087A7 (fi) 1983-10-02
DD209619A5 (de) 1984-05-16
FI831087A0 (fi) 1983-03-30
FI831087L (fi) 1983-10-02
GB8308956D0 (en) 1983-05-11
GB2117773B (en) 1985-08-29
JPS58208262A (ja) 1983-12-03
IT1194184B (it) 1988-09-14
IL68079A0 (en) 1983-06-15
CA1210027A (en) 1986-08-19
AT384423B (de) 1987-11-10
DE3311895A1 (de) 1983-10-06
DK148783A (da) 1983-10-02
IL68079A (en) 1986-10-31
IT8320428A1 (it) 1984-10-01
NL8301175A (nl) 1983-11-01
IT8320428A0 (it) 1983-04-01
FR2524464A1 (fr) 1983-10-07
ATA116983A (de) 1987-04-15
FR2524464B1 (fr) 1986-05-30
CH656121B (de) 1986-06-13
BE896279A (fr) 1983-09-28
DK148783D0 (da) 1983-03-30
ES521096A0 (es) 1984-06-01
ES8405366A1 (es) 1984-06-01
GB2117773A (en) 1983-10-19
SE8301817L (sv) 1983-10-02
SE8301817D0 (sv) 1983-03-30
YU77683A (en) 1985-12-31

Similar Documents

Publication Publication Date Title
SU628812A3 (ru) Способ получени органических содинений
DE69619809T2 (de) Verfahren zur herstellung von (s)-3-(aminoethyl)-5-metylhexansäure
US4851588A (en) Novel process for the preparation of bronopol
JPS6045631B2 (ja) フエニルグリオキザル酸エステの製造法
HU185518B (en) Process for preparing 2-/e/-phenyl-methylene-cycloheptan-1-one-/e/-oxime
DE60108105T2 (de) Verfahren zur Herstellung von 5-substituierten Isobenzofuranen
US2948725A (en) Flow sheet-process
JPH04504405A (ja) シアノジエン類、ハロピリジン類、中間体及びそれらの製造方法
CH619955A5 (de)
DE4408083C1 (de) Verfahren zur Herstellung von 4-Fluoralkoxyzimtsäurenitrilen
HU190387B (en) Process for producing 2-bracket-z-bracket closed-phenyl-methylene-cycloheptane derivatives
EP0115811B1 (de) 2,4-Dichlor-5-thiazolcarboxaldehyd und ein Verfahren zu seiner Herstellung
EP0163926B1 (de) Verfahren zur Herstellung von Acemetacin
DE1768582C3 (de)
EP0161617A2 (de) Zwischenprodukte sowie Verfahren zur Herstellung von Zwischenproducten für die Synthese von Cephalosporinen
EP0396014A2 (de) Substituierte Biphenylcarbonsäuren, Verfahren zu ihrer Herstellung und neue Zwischenprodukte
US4254279A (en) Ester resolution process
US4128579A (en) Process for the manufacture of α,β-unsaturated cycloaliphatic ketoximes
EP0641764A2 (de) Verfahren zur Herstellung von Hydroxyalkylaminonitrobenzol-Derivaten
FI56672C (fi) Nytt foerfarande foer framstaellning av 2-amino-benzaminer
JP2986003B2 (ja) ２−アルキル−３−スチリルオキシランカルボン酸エステル及びその製法
US4195038A (en) Preparation of 3-bromo-2-hydroxy-4,4,5,5-tetramethylcyclopenta-2-enone
DE1543869B1 (de) Verfahren zur Herstellung von Hydroxybenzonitrilen
HU193454B (en) Process for producing 3-phenyl-butyraldehyde derivatives
CH638487A5 (en) Novel substituted di(phenylethyl)amines

Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee