HU9403473D0 - Process for attenuated varicella zoster virus vaccine production - Google Patents

Process for attenuated varicella zoster virus vaccine production

Info

Publication number: HU9403473D0
Authority: HU; Hungary
Prior art keywords: medium; virus vaccine; zoster virus; varicella zoster; vaccine production
Prior art date: 1992-06-04

Application number

HU9403473A

Other languages

English (en)

Other versions

HUT71863A (en

HU220080B (hu

Inventor

Philip J Provost

David L Krah

Paul A Friedmann

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-06-04

Filing date

1993-05-26

Publication date

1995-02-28

1992-06-04 Priority claimed from US07/893,295 external-priority patent/US5360736A/en

1993-05-26 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

1995-02-28 Publication of HU9403473D0 publication Critical patent/HU9403473D0/hu

1996-02-28 Publication of HUT71863A publication Critical patent/HUT71863A/hu

2001-10-28 Publication of HU220080B publication Critical patent/HU220080B/hu

Links

238000000034 method Methods 0.000 title abstract 2
229940124863 Varicella-zoster virus vaccine Drugs 0.000 title 1
230000002238 attenuated effect Effects 0.000 title 1
150000002632 lipids Chemical class 0.000 abstract 3
239000007320 rich medium Substances 0.000 abstract 3
239000002609 medium Substances 0.000 abstract 2
238000012258 culturing Methods 0.000 abstract 1
239000012737 fresh medium Substances 0.000 abstract 1
238000010899 nucleation Methods 0.000 abstract 1
239000012090 serum-supplement Substances 0.000 abstract 1
239000002356 single layer Substances 0.000 abstract 1
239000013589 supplement Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
- A61K39/25—Varicella-zoster virus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/36—Lipids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16734—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Virology (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Biotechnology (AREA)
Animal Behavior & Ethology (AREA)
Microbiology (AREA)
Biomedical Technology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Wood Science & Technology (AREA)
Genetics & Genomics (AREA)
Epidemiology (AREA)
Mycology (AREA)
Immunology (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Cell Biology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Molecular Biology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

HU9403473A 1992-06-04 1993-05-26 Eljárás gyengített Varicella zoster vírus vakcina előállítására HU220080B (hu)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US89403992A	1992-06-04	1992-06-04
US07/893,295 US5360736A (en)	1992-06-04	1992-06-04	Process for attenuated varicella zoster virus vaccine production
PCT/US1993/004986 WO1993024616A1 (en)	1992-06-04	1993-05-26	Process for attenuated varicella zoster virus vaccine production

Publications (3)

Publication Number	Publication Date
HU9403473D0 true HU9403473D0 (en)	1995-02-28
HUT71863A HUT71863A (en)	1996-02-28
HU220080B HU220080B (hu)	2001-10-28

Family

ID=27129046

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HU9403473A HU220080B (hu)	1992-06-04	1993-05-26	Eljárás gyengített Varicella zoster vírus vakcina előállítására

Country Status (28)

Country	Link
US (1)	US5607852A (hu)
EP (2)	EP0573107B1 (hu)
JP (2)	JP2599552B2 (hu)
KR (1)	KR100350169B1 (hu)
CN (2)	CN1069216C (hu)
AT (2)	ATE419332T1 (hu)
AU (2)	AU4392193A (hu)
BG (1)	BG62176B1 (hu)
CA (1)	CA2097019C (hu)
CZ (2)	CZ289574B6 (hu)
DE (2)	DE69330850T2 (hu)
DK (2)	DK0573107T3 (hu)
ES (2)	ES2161702T3 (hu)
FI (1)	FI117758B (hu)
GR (1)	GR3036812T3 (hu)
HU (1)	HU220080B (hu)
MX (1)	MX9303274A (hu)
NO (1)	NO314068B1 (hu)
NZ (1)	NZ253527A (hu)
PT (2)	PT573107E (hu)
RO (1)	RO114906B1 (hu)
RS (1)	RS50330B (hu)
RU (1)	RU2126269C1 (hu)
SK (1)	SK279387B6 (hu)
TW (1)	TW349868B (hu)
UA (1)	UA27137C2 (hu)
WO (1)	WO1993024616A1 (hu)
YU (1)	YU49210B (hu)

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KR0177323B1 (ko) *	1996-02-16	1999-04-01	성재갑	바이러스 백신 생산에 유용한 사람 이배체 폐세포 및 이를 이용한 수두 백신의 제조방법
EP1983044B1 (en) *	1996-10-10	2016-08-10	Life Technologies Corporation	Animal cell culture media comprising plant-derived nutrients
US20040171152A1 (en) *	1996-10-10	2004-09-02	Invitrogen Corporation	Animal cell culture media comprising non-animal or plant-derived nutrients
GB9716611D0 (en) *	1997-08-07	1997-10-08	Cantab Pharmaceuticals Res Ltd	Virus preparations and methods
US6210683B1 (en)	1997-09-05	2001-04-03	Merck & Co., Inc.	Stabilizers containing recombinant human serum albumin for live virus vaccines
GB9804632D0 (en)	1998-03-05	1998-04-29	Cantab Pharma Res	Virus preparations and methods
KR100378909B1 (ko) *	1998-03-18	2003-12-18	주식회사 엘지생명과학	사람세포주를이용한풍진백신의생산수율증대방법
GB9808922D0 (en) *	1998-04-24	1998-06-24	Cantab Pharmaceuticals Res Ltd	Virus preparations
WO1999057246A1 (en) *	1998-05-01	1999-11-11	Life Technologies, Inc.	Animal cell culture media comprising non-animal or plant-derived nutrients
US20060286668A1 (en) *	1999-04-30	2006-12-21	Invitrogen Corporation	Animal-cell culture media comprising non-animal or plant-derived nutrients
JP3946045B2 (ja) *	2000-01-31	2007-07-18	財団法人阪大微生物病研究会	弱毒生水痘ワクチンの品質管理方法
CN1318580C (zh) *	2003-07-10	2007-05-30	北京科兴生物制品有限公司	可满足灭活疫苗生产的sars病毒规模化制备及灭活的方法
RU2259214C1 (ru) *	2004-01-28	2005-08-27	Федеральное государственное унитарное предприятие "Научно-производственное объединение по медицинским иммунобиологическим препаратам "Микроген" Министерства здравоохранения Российской Федерации	Способ получения вакцины оспенной инактивированной сухой "оспавир"
US7344839B2 (en) *	2004-12-23	2008-03-18	Aurx, Inc.	Virus preparations and methods
CN101578362A (zh) *	2006-10-17	2009-11-11	米迪缪尼有限公司	影响病毒脂质的成分
US20080294361A1 (en) *	2007-05-24	2008-11-27	Popp Shane M	Intelligent execution system for the monitoring and execution of vaccine manufacturing
EP2310495B1 (en) *	2008-08-11	2017-11-22	Sanofi Pasteur Biologics, LLC	Compositions and methods for the production of alpha-herpesvirus 2
CN101967466A (zh)	2009-07-28	2011-02-09	新泽西医学院	Orf7缺陷型水痘病毒株、含有该毒株的疫苗及其应用
FR2952825B1 (fr)	2009-11-24	2012-05-25	Goaster Jacqueline Le	Utilisation d'un vaccin contre le virus vzv/hsv3 pour traiter les infections herpetiques par le virus hsv1 et/ou le virus hsv2
CN101972474B (zh) *	2010-11-11	2012-06-27	长春祈健生物制品有限公司	冻干带状疱疹减毒活疫苗及制备方法
JP2014508522A (ja) *	2011-02-24	2014-04-10	モガムバイオテクノロジーリサーチインスティチュート	新規な水痘帯状疱疹ウイルス株及びそれを用いた水痘及び帯状疱疹ウイルスワクチン
WO2014062060A1 (en) *	2012-10-18	2014-04-24	Erasmus University Medical Center Rotterdam	New method for producing high titer cell-free vzv vaccine virus
CN103074304B (zh) *	2013-01-28	2016-01-13	江苏健安生物科技有限公司	高水平人二倍体细胞培养水痘-带状疱疹疫苗病毒方法
WO2015034807A2 (en) *	2013-09-05	2015-03-12	Merck Sharp & Dohme Corp.	Methods of immunization with varicella zoster virus antigen
CN103740735B (zh) *	2013-12-31	2016-04-06	李越希	化学合成的HSV2病毒gC糖蛋白胞外区基因片段及其表达、应用
DK3226894T3 (da) *	2014-12-01	2019-10-21	Transgene Sa	Stabile flydende vacciniavirus-formuleringer
RU2637093C1 (ru) *	2016-12-20	2017-11-29	Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт вакцин и сывороток им. И.И. Мечникова" (ФГБНУ НИИВС им. И.И. Мечникова)	Способ получения живой культуральной аттенуированной вакцины для профилактики ветряной оспы
CN107174658B (zh) *	2017-04-29	2020-11-27	安徽智飞龙科马生物制药有限公司	人用水痘病毒灭活疫苗及其制备方法

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1993
- 1993-05-26 CZ CZ19943045A patent/CZ289574B6/cs not_active IP Right Cessation
- 1993-05-26 RU RU94046296A patent/RU2126269C1/ru active
- 1993-05-26 HU HU9403473A patent/HU220080B/hu unknown
- 1993-05-26 SK SK1480-94A patent/SK279387B6/sk not_active IP Right Cessation
- 1993-05-26 RO RO94-01924A patent/RO114906B1/ro unknown
- 1993-05-26 US US08/347,345 patent/US5607852A/en not_active Expired - Lifetime
- 1993-05-26 CA CA002097019A patent/CA2097019C/en not_active Expired - Lifetime
- 1993-05-26 KR KR1019940704393A patent/KR100350169B1/ko not_active Expired - Lifetime
- 1993-05-26 WO PCT/US1993/004986 patent/WO1993024616A1/en not_active Ceased
- 1993-05-26 NZ NZ253527A patent/NZ253527A/en not_active IP Right Cessation
- 1993-05-26 AU AU43921/93A patent/AU4392193A/en not_active Abandoned
- 1993-05-26 UA UA94129122A patent/UA27137C2/uk unknown
- 1993-05-27 AT AT01200292T patent/ATE419332T1/de active
- 1993-05-27 EP EP93201521A patent/EP0573107B1/en not_active Expired - Lifetime
- 1993-05-27 EP EP01200292A patent/EP1097988B1/en not_active Expired - Lifetime
- 1993-05-27 ES ES93201521T patent/ES2161702T3/es not_active Expired - Lifetime
- 1993-05-27 DK DK93201521T patent/DK0573107T3/da active
- 1993-05-27 PT PT93201521T patent/PT573107E/pt unknown
- 1993-05-27 PT PT01200292T patent/PT1097988E/pt unknown
- 1993-05-27 TW TW082104197A patent/TW349868B/zh not_active IP Right Cessation
- 1993-05-27 DE DE69330850T patent/DE69330850T2/de not_active Expired - Lifetime
- 1993-05-27 DK DK01200292T patent/DK1097988T3/da active
- 1993-05-27 AT AT93201521T patent/ATE206311T1/de active
- 1993-05-27 DE DE69334254T patent/DE69334254D1/de not_active Expired - Lifetime
- 1993-05-27 ES ES01200292T patent/ES2317869T3/es not_active Expired - Lifetime
- 1993-06-01 MX MX9303274A patent/MX9303274A/es unknown
- 1993-06-02 YU YU38893A patent/YU49210B/sh unknown
- 1993-06-03 AU AU40036/93A patent/AU673167B2/en not_active Expired
- 1993-06-03 CN CN93106673A patent/CN1069216C/zh not_active Expired - Lifetime
- 1993-06-04 JP JP5134711A patent/JP2599552B2/ja not_active Expired - Lifetime
1994
- 1994-12-01 BG BG99227A patent/BG62176B1/bg unknown
- 1994-12-02 FI FI945697A patent/FI117758B/fi not_active IP Right Cessation
- 1994-12-02 NO NO19944654A patent/NO314068B1/no not_active IP Right Cessation
1996
- 1996-10-02 JP JP26218596A patent/JP3156962B2/ja not_active Expired - Lifetime
1998
- 1998-04-29 CZ CZ19981319A patent/CZ289690B6/cs not_active IP Right Cessation
2000
- 2000-10-05 CN CN00133104A patent/CN1307902A/zh active Granted
2001
- 2001-10-05 GR GR20010401425T patent/GR3036812T3/el unknown
2004
- 2004-01-26 RS YUP-75/04(62)P-388/93A patent/RS50330B/sr unknown

Also Published As

Publication number	Publication date
GR3036812T3 (en)	2002-01-31
ATE206311T1 (de)	2001-10-15
EP1097988A1 (en)	2001-05-09
PT573107E (pt)	2002-02-28
BG99227A (bg)	1995-07-28
JPH09107958A (ja)	1997-04-28
NO944654D0 (no)	1994-12-02
CA2097019C (en)	2007-07-24
CZ289574B6 (cs)	2002-02-13
PT1097988E (pt)	2009-03-05
HUT71863A (en)	1996-02-28
JPH06172215A (ja)	1994-06-21
AU4003693A (en)	1993-12-09
MX9303274A (es)	1994-01-31
KR100350169B1 (ko)	2004-05-20
CN1069216C (zh)	2001-08-08
RU2126269C1 (ru)	1999-02-20
FI945697A0 (fi)	1994-12-02
EP0573107B1 (en)	2001-10-04
RS50330B (sr)	2009-11-10
YU7504A (sh)	2006-08-17
CZ304594A3 (en)	1995-10-18
YU38893A (sh)	1996-02-19
EP0573107A2 (en)	1993-12-08
JP2599552B2 (ja)	1997-04-09
RO114906B1 (ro)	1999-08-30
EP1097988B1 (en)	2008-12-31
FI117758B (fi)	2007-02-15
DK0573107T3 (da)	2001-11-12
EP0573107A3 (en)	1995-04-26
DE69330850T2 (de)	2002-04-11
JP3156962B2 (ja)	2001-04-16
DK1097988T3 (da)	2009-05-04
CN1307902A (zh)	2001-08-15
YU49210B (sh)	2004-09-03
AU4392193A (en)	1993-12-30
TW349868B (en)	1999-01-11
NO314068B1 (no)	2003-01-27
UA27137C2 (uk)	2000-02-28
WO1993024616A1 (en)	1993-12-09
DE69330850D1 (de)	2001-11-08
ES2161702T3 (es)	2001-12-16
FI945697L (fi)	1995-01-26
HU220080B (hu)	2001-10-28
NO944654L (no)	1995-02-03
US5607852A (en)	1997-03-04
NZ253527A (en)	1996-09-25
AU673167B2 (en)	1996-10-31
CN1082923A (zh)	1994-03-02
SK279387B6 (sk)	1998-10-07
DE69334254D1 (de)	2009-02-12
BG62176B1 (bg)	1999-04-30
ATE419332T1 (de)	2009-01-15
SK148094A3 (en)	1995-07-11
CA2097019A1 (en)	1993-12-05
ES2317869T3 (es)	2009-05-01
CZ289690B6 (cs)	2002-03-13

Legal Events

Date

Code

Title

Description

2010-05-28

GB9A

Succession in title

Owner name: MERCK SHARP & DOHME CORP., US

Free format text: FORMER OWNER(S): MERCK AND CO. INC., US

2013-04-29