HUE054232T2 - Új hibrid actriib ligandum trap fehérjék az izomsorvadásos betegségek kezelésére - Google Patents

Új hibrid actriib ligandum trap fehérjék az izomsorvadásos betegségek kezelésére

Info

Publication number
HUE054232T2
HUE054232T2 HUE16783603A HUE16783603A HUE054232T2 HU E054232 T2 HUE054232 T2 HU E054232T2 HU E16783603 A HUE16783603 A HU E16783603A HU E16783603 A HUE16783603 A HU E16783603A HU E054232 T2 HUE054232 T2 HU E054232T2
Authority
HU
Hungary
Prior art keywords
treatment
muscular atrophy
new hybrid
actriib ligand
ligand trap
Prior art date
Application number
HUE16783603A
Other languages
English (en)
Inventor
Hq Han
Xiaolan Zhou
Original Assignee
Biogen Ma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Ma Inc filed Critical Biogen Ma Inc
Publication of HUE054232T2 publication Critical patent/HUE054232T2/hu

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/495—Transforming growth factor [TGF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cell Biology (AREA)
  • Rheumatology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
HUE16783603A 2015-04-22 2016-04-12 Új hibrid actriib ligandum trap fehérjék az izomsorvadásos betegségek kezelésére HUE054232T2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562150994P 2015-04-22 2015-04-22
US201562262356P 2015-12-02 2015-12-02

Publications (1)

Publication Number Publication Date
HUE054232T2 true HUE054232T2 (hu) 2021-08-30

Family

ID=57144520

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE16783603A HUE054232T2 (hu) 2015-04-22 2016-04-12 Új hibrid actriib ligandum trap fehérjék az izomsorvadásos betegségek kezelésére

Country Status (24)

Country Link
US (4) US10913782B2 (hu)
EP (2) EP3286206B1 (hu)
JP (2) JP6959487B2 (hu)
KR (1) KR102777477B1 (hu)
CN (1) CN107683287B (hu)
AU (2) AU2016251640B2 (hu)
CA (1) CA2983440C (hu)
CY (1) CY1124124T1 (hu)
DK (1) DK3286206T3 (hu)
ES (1) ES2856001T3 (hu)
HR (1) HRP20210725T1 (hu)
HU (1) HUE054232T2 (hu)
IL (1) IL255070B (hu)
LT (1) LT3286206T (hu)
MX (1) MX2017013520A (hu)
PL (1) PL3286206T3 (hu)
PT (1) PT3286206T (hu)
RS (1) RS61881B1 (hu)
RU (1) RU2733492C2 (hu)
SG (2) SG11201708351XA (hu)
SI (1) SI3286206T1 (hu)
SM (1) SMT202100294T1 (hu)
WO (1) WO2016171948A1 (hu)
ZA (2) ZA201707821B (hu)

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Also Published As

Publication number Publication date
KR102777477B1 (ko) 2025-03-10
US20180148491A1 (en) 2018-05-31
US11292826B2 (en) 2022-04-05
IL255070B (en) 2022-05-01
US20200362009A1 (en) 2020-11-19
IL255070A0 (en) 2017-12-31
US20240262883A1 (en) 2024-08-08
SI3286206T1 (sl) 2021-07-30
HK1251588A1 (zh) 2019-02-01
RS61881B1 (sr) 2021-06-30
CN107683287B (zh) 2022-05-06
JP6959487B2 (ja) 2021-11-02
RU2017138537A3 (hu) 2019-08-01
WO2016171948A1 (en) 2016-10-27
RU2733492C2 (ru) 2020-10-02
SMT202100294T1 (it) 2021-07-12
DK3286206T3 (da) 2021-05-03
JP2018512873A (ja) 2018-05-24
EP3286206B1 (en) 2021-02-17
AU2016251640B2 (en) 2020-07-16
BR112017022658A2 (pt) 2018-07-17
CY1124124T1 (el) 2022-05-27
AU2016251640A1 (en) 2017-11-23
CA2983440A1 (en) 2016-10-27
CN107683287A (zh) 2018-02-09
RU2017138537A (ru) 2019-05-22
EP3286206A4 (en) 2018-12-05
US20220332783A1 (en) 2022-10-20
US10913782B2 (en) 2021-02-09
ZA202007118B (en) 2023-03-29
SG11201708351XA (en) 2017-11-29
EP3286206A1 (en) 2018-02-28
EP3878857A1 (en) 2021-09-15
AU2020250216B2 (en) 2022-07-14
JP2022000027A (ja) 2022-01-04
CA2983440C (en) 2024-03-12
ZA201707821B (en) 2021-03-31
JP7320571B2 (ja) 2023-08-03
AU2020250216A1 (en) 2020-11-05
KR20180006386A (ko) 2018-01-17
US11932677B2 (en) 2024-03-19
SG10201913747PA (en) 2020-03-30
PT3286206T (pt) 2021-04-01
PL3286206T3 (pl) 2021-09-13
MX2017013520A (es) 2018-05-22
LT3286206T (lt) 2021-06-10
HRP20210725T1 (hr) 2021-06-25
ES2856001T3 (es) 2021-09-27

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