HUP0303270A3 - Isoxazoline derivatives as anti-depressants, process for their preparation and pharmaceutical compositions containing them - Google Patents

Isoxazoline derivatives as anti-depressants, process for their preparation and pharmaceutical compositions containing them

Info

Publication number: HUP0303270A3
Authority: HU; Hungary
Prior art keywords: depressants; preparation; pharmaceutical compositions; compositions containing; isoxazoline derivatives
Prior art date: 2001-02-21

Application number

HU0303270A

Other languages

English (en)

Hungarian (hu)

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-02-21

Filing date

2002-02-13

Publication date

2007-03-28

2002-02-13 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2004-01-28 Publication of HUP0303270A2 publication Critical patent/HUP0303270A2/hu

2007-03-28 Publication of HUP0303270A3 publication Critical patent/HUP0303270A3/hu

Links

230000001430 anti-depressive effect Effects 0.000 title 1
239000000935 antidepressant agent Substances 0.000 title 1
229940005513 antidepressants Drugs 0.000 title 1
150000002547 isoxazolines Chemical class 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Epidemiology (AREA)
Psychiatry (AREA)
Child & Adolescent Psychology (AREA)
Hematology (AREA)
Obesity (AREA)
Pain & Pain Management (AREA)
Diabetes (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

HU0303270A 2001-02-21 2002-02-13 Isoxazoline derivatives as anti-depressants, process for their preparation and pharmaceutical compositions containing them HUP0303270A3 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP01200611		2001-02-21
EP01201264		2001-04-05
PCT/EP2002/001567 WO2002066484A1 (en)	2001-02-21	2002-02-13	Isoxazoline derivatives as anti-depressants

Publications (2)

Publication Number	Publication Date
HUP0303270A2 HUP0303270A2 (hu)	2004-01-28
HUP0303270A3 true HUP0303270A3 (en)	2007-03-28

Family

ID=26076836

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HU0303270A HUP0303270A3 (en)	2001-02-21	2002-02-13	Isoxazoline derivatives as anti-depressants, process for their preparation and pharmaceutical compositions containing them

Country Status (32)

Country	Link
US (1)	US7169786B2 (cs)
EP (1)	EP1368358B1 (cs)
JP (1)	JP3953424B2 (cs)
KR (1)	KR100848898B1 (cs)
CN (1)	CN100400540C (cs)
AR (1)	AR035685A1 (cs)
AT (1)	ATE337322T1 (cs)
AU (1)	AU2002244717B2 (cs)
BG (1)	BG107984A (cs)
BR (1)	BR0207433A (cs)
CA (1)	CA2437505C (cs)
CY (1)	CY1106448T1 (cs)
CZ (1)	CZ20032515A3 (cs)
DE (1)	DE60214138T2 (cs)
DK (1)	DK1368358T3 (cs)
EA (1)	EA006747B1 (cs)
EE (1)	EE200300398A (cs)
EG (1)	EG23929A (cs)
ES (1)	ES2271230T3 (cs)
HR (1)	HRP20030647A2 (cs)
HU (1)	HUP0303270A3 (cs)
IL (2)	IL157470A0 (cs)
MX (1)	MXPA03007432A (cs)
MY (1)	MY137836A (cs)
NO (1)	NO20033700L (cs)
NZ (1)	NZ526741A (cs)
PL (1)	PL208593B1 (cs)
PT (1)	PT1368358E (cs)
SI (1)	SI1368358T1 (cs)
SK (1)	SK11612003A3 (cs)
TW (1)	TWI257392B (cs)
WO (1)	WO2002066484A1 (cs)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0203299D0 (en) *	2002-02-12	2002-03-27	Glaxo Group Ltd	Novel compounds
NZ536109A (en) *	2002-04-02	2006-06-30	Janssen Pharmaceutica Nv	Substituted amino isoxazoline derivatives and their use as anti-depressants
AR040967A1 (es) *	2002-08-12	2005-04-27	Janssen Pharmaceutica Nv	Derivados de isoxazolina triciclicos c- sustituidos y su uso como anti- depresivos
ATE456568T1 (de) *	2002-08-15	2010-02-15	Janssen Pharmaceutica Nv	Kondensierte heterocyclische isoxazolinderivate und deren verwendung als antidepressiva
ATE387455T1 (de) *	2002-08-21	2008-03-15	Janssen Pharmaceutica Nv	C6- und c9-substituierte chromeno(4,3- c)isoxazoline und ihre verwendung als anti- depressiva
BRPI0408136A (pt) *	2003-03-07	2006-03-01	Astellas Pharma Inc	derivados heterocìclicos contendo nitrogênio tendo estirila 2,6-dissubstituìda
ES2319539T3 (es) *	2003-09-17	2009-05-08	Janssen Pharmaceutica Nv	Compuestos heterociclicos condensados como moduladores del receptor de serotonina.
EP1944306A1 (en) *	2003-09-17	2008-07-16	Janssen Pharmaceutica, N.V.	Fused heterocyclic compounds as serotonin receptor modulators
JP2008521771A (ja) *	2004-11-26	2008-06-26	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	改良された抗精神病活性および抗不安症活性を有するイソキサゾリン−インドール誘導体
WO2008112483A2 (en)	2007-03-09	2008-09-18	Sanofi-Aventis	Substituted dihydro and tetrahydro oxazolopyrimidinones, preparation and use thereof
WO2008154442A1 (en) *	2007-06-08	2008-12-18	Helicon Therapeutics, Inc.	Therapeutic pyrazoloquinoline urea derivatives
JP2011507835A (ja)	2007-12-21	2011-03-10	アンドレイ・アレクサンドロビッチ・イワシェンコ	α−アドレナリン受容体、ドーパミン、ヒスタミン、イミダゾリン及びセロトニン受容体のリガンド並びにその使用
AR078171A1 (es)	2009-09-15	2011-10-19	Sanofi Aventis	Dihidrobenzocicloalquiloximetil-oxazolopirimidinonas sustituidas, preparacion y uso de las mismas

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2055011T3 (es) *	1988-09-19	1994-08-16	Akzo Nv	Un procedimiento para la preparacion de derivados de tetrahidronaftaleno e indano.
US5880121A (en) *	1996-01-05	1999-03-09	Hoechst Marion Roussel Inc.	4,5-dihydronaphth (1,2-c) isoxazoles and derivatives thereof
CN1082963C (zh) *	1996-04-12	2002-04-17	詹森药业有限公司	异噁唑烷衍生物
HUP9602763A3 (en) *	1996-10-09	1999-05-28	Egyt Gyogyszervegyeszeti Gyar	3-phenyl isoxazole derivatives, process for producing them and pharmaceutical compositions containing the same
CA2346396C (en) *	1998-10-09	2009-04-28	Janssen Pharmaceutica N.V.	4,5-dihydro-isoxazole derivatives and their pharmaceutical use

2002
- 2002-02-13 MX MXPA03007432A patent/MXPA03007432A/es active IP Right Grant
- 2002-02-13 PT PT02712909T patent/PT1368358E/pt unknown
- 2002-02-13 ES ES02712909T patent/ES2271230T3/es not_active Expired - Lifetime
- 2002-02-13 HU HU0303270A patent/HUP0303270A3/hu unknown
- 2002-02-13 IL IL15747002A patent/IL157470A0/xx unknown
- 2002-02-13 NZ NZ526741A patent/NZ526741A/en unknown
- 2002-02-13 AT AT02712909T patent/ATE337322T1/de not_active IP Right Cessation
- 2002-02-13 CN CNB028052439A patent/CN100400540C/zh not_active Expired - Fee Related
- 2002-02-13 BR BR0207433-8A patent/BR0207433A/pt not_active IP Right Cessation
- 2002-02-13 EE EEP200300398A patent/EE200300398A/xx unknown
- 2002-02-13 EP EP02712909A patent/EP1368358B1/en not_active Expired - Lifetime
- 2002-02-13 HR HR20030647A patent/HRP20030647A2/hr not_active Application Discontinuation
- 2002-02-13 US US10/468,555 patent/US7169786B2/en not_active Expired - Lifetime
- 2002-02-13 SK SK1161-2003A patent/SK11612003A3/sk unknown
- 2002-02-13 JP JP2002565998A patent/JP3953424B2/ja not_active Expired - Lifetime
- 2002-02-13 DK DK02712909T patent/DK1368358T3/da active
- 2002-02-13 CA CA2437505A patent/CA2437505C/en not_active Expired - Lifetime
- 2002-02-13 SI SI200230433T patent/SI1368358T1/sl unknown
- 2002-02-13 AU AU2002244717A patent/AU2002244717B2/en not_active Expired
- 2002-02-13 DE DE60214138T patent/DE60214138T2/de not_active Expired - Lifetime
- 2002-02-13 CZ CZ20032515A patent/CZ20032515A3/cs unknown
- 2002-02-13 KR KR1020037008328A patent/KR100848898B1/ko not_active Expired - Fee Related
- 2002-02-13 PL PL363264A patent/PL208593B1/pl unknown
- 2002-02-13 WO PCT/EP2002/001567 patent/WO2002066484A1/en not_active Ceased
- 2002-02-13 EA EA200300915A patent/EA006747B1/ru not_active IP Right Cessation
- 2002-02-19 MY MYPI20020548A patent/MY137836A/en unknown
- 2002-02-19 EG EG20020197A patent/EG23929A/xx active
- 2002-02-20 AR ARP020100583A patent/AR035685A1/es unknown
- 2002-02-20 TW TW091102853A patent/TWI257392B/zh not_active IP Right Cessation
2003
- 2003-07-08 BG BG107984A patent/BG107984A/bg unknown
- 2003-08-19 IL IL157470A patent/IL157470A/en unknown
- 2003-08-20 NO NO20033700A patent/NO20033700L/no not_active Application Discontinuation
2006
- 2006-11-22 CY CY20061101693T patent/CY1106448T1/el unknown

Also Published As

Publication number	Publication date
CY1106448T1 (el)	2011-10-12
NZ526741A (en)	2004-04-30
SK11612003A3 (sk)	2004-04-06
IL157470A (en)	2008-07-08
PL208593B1 (pl)	2011-05-31
HK1065537A1 (zh)	2005-02-25
DK1368358T3 (da)	2007-01-02
ES2271230T3 (es)	2007-04-16
EE200300398A (et)	2003-12-15
CA2437505C (en)	2010-02-09
JP3953424B2 (ja)	2007-08-08
SI1368358T1 (sl)	2007-02-28
NO20033700D0 (no)	2003-08-20
PL363264A1 (en)	2004-11-15
HUP0303270A2 (hu)	2004-01-28
DE60214138T2 (de)	2007-03-29
EA200300915A1 (ru)	2004-06-24
EP1368358A1 (en)	2003-12-10
US7169786B2 (en)	2007-01-30
BR0207433A (pt)	2004-06-01
ATE337322T1 (de)	2006-09-15
BG107984A (bg)	2004-09-30
HRP20030647A2 (en)	2005-06-30
DE60214138D1 (de)	2006-10-05
EP1368358B1 (en)	2006-08-23
JP2004518748A (ja)	2004-06-24
CZ20032515A3 (cs)	2003-12-17
AR035685A1 (es)	2004-06-23
CA2437505A1 (en)	2002-08-29
US20040122037A1 (en)	2004-06-24
CN100400540C (zh)	2008-07-09
MXPA03007432A (es)	2003-11-18
WO2002066484A1 (en)	2002-08-29
CN1492871A (zh)	2004-04-28
KR20030076590A (ko)	2003-09-26
EG23929A (en)	2008-01-14
TWI257392B (en)	2006-07-01
AU2002244717B2 (en)	2007-07-19
EA006747B1 (ru)	2006-04-28
KR100848898B1 (ko)	2008-07-29
NO20033700L (no)	2003-10-21
IL157470A0 (en)	2004-03-28
PT1368358E (pt)	2007-01-31
MY137836A (en)	2009-03-31

Similar Documents

Publication	Publication Date	Title
HUP0401619A3 (en)	2008-03-28	Phenethanolamine derivatives, process for their preparation and pharmaceutical composition containing them
HUP0301187A3 (en)	2010-03-29	Novel benzyl-piperidine-derivatives, process for their preparation and pharmaceutical compositions containing them
HUP0402225A3 (en)	2006-01-30	Macrolide-compounds, process for their preparation and pharmaceutical compositions containing them
HUP0301069A3 (en)	2004-09-28	Novel biarylcarboxamides, process for their preparation, pharmaceutical compositions containing them and their use
HUP0402161A3 (en)	2010-06-28	Nicotin-or isonicotin benzothiazole derivatives, process for their preparation and pharmaceutical compositions containing them
HUP0402264A3 (en)	2010-03-29	Substituted 2-thio-3,5-dicyano-4-phenyl-6-aminopyridines process for preparing them, pharmaceutical compositions containing them and use thereof
HUP0401005A3 (en)	2007-11-28	Oxazolidinone and/or isoxazoline antibacterials, process for their preparation, their use and pharmaceutical compositions containing them
HUP0300894A3 (en)	2008-05-28	Substituted beta-carbolines, process for their preparation, pharmaceutical compositions containing them and their use
HUP0400888A3 (en)	2008-03-28	Substituted cyclohexane-1,4-diamine derivatives, process for their preparation and pharmaceutical compositions containing them
IL156662A0 (en)	2004-01-04	Oxazolidinone derivatives, process for the preparation thereof and pharmaceutical compositions containing the same
HUP0400040A2 (hu)	2004-04-28	Szulfonamidok, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények
HUP0303270A3 (en)	2007-03-28	Isoxazoline derivatives as anti-depressants, process for their preparation and pharmaceutical compositions containing them
HUP0100489A3 (en)	2002-10-28	New piperidine-4-sulphonamide compounds, process for their preparation and pharmaceutical compositions containing them
HUP0400317A3 (en)	2007-10-29	Beta-carboline derivatives, process for their preparation, their use and pharmaceutical compositions containing them
HUP0302515A3 (en)	2005-06-28	Sulfanidothienopyrimidines, process for their preparation and pharmaceutical compositions containing them
AU2003231920A8 (en)	2003-10-13	Antiinfectve compounds, process for their preparation and pharmaceutical compositions containing them
HUP0204001A3 (en)	2005-04-28	Substituted aminomethyl-phenyl-cyclohexane derivatives, process for their preparation and pharmaceutical compositions containing them
HUP0401082A3 (en)	2011-07-28	Substituted 4-aminocyclohexanols, process for their preparation and pharmaceutical compositions containing them
HUP0303105A3 (en)	2005-05-30	Novel aminocyclohexane derivatives, process for their preparation, pharmaceutical compositions containing them and their use
HUP0303361A3 (en)	2007-03-28	Substituted 1-aminobutan-3-ol derivatives, process for their preparation and pharmaceutical compositions containing them
SI1118610T1 (en)	2002-12-31	Benzenesulfonamide derivatives, process for their preparation and pharmaceutical compositions containing them
HUP0301254A3 (en)	2008-03-28	Novel compounds, process fo their preparation and pharmaceutical compositions containing them
HUP0203859A3 (en)	2008-01-28	Aminomethyl-phenyl-cyclohexanone derivatives, process for their preparation, pharmaceutical compositions containing them and their use
SI1241169T1 (en)	2003-12-31	Isoindoloindolone derivatives, process for their preparation and pharmaceutical compositions containing them
HUP0302905A3 (en)	2006-05-29	Triazolo-epothilone-analogs, process for their preparation and pharmaceutical compositions containing them

Legal Events

Date	Code	Title	Description
2010-10-28	FD9A	Lapse of provisional protection due to non-payment of fees