ID17266A - Antagonis antagonis reseptor d4 dopamin benzoksazinon - Google Patents

Antagonis antagonis reseptor d4 dopamin benzoksazinon

Info

Publication number
ID17266A
ID17266A IDP971778A ID971778A ID17266A ID 17266 A ID17266 A ID 17266A ID P971778 A IDP971778 A ID P971778A ID 971778 A ID971778 A ID 971778A ID 17266 A ID17266 A ID 17266A
Authority
ID
Indonesia
Prior art keywords
antagonists
benzoksazinon
dopamin
receptor
receptor antagonists
Prior art date
Application number
IDP971778A
Other languages
English (en)
Indonesian (id)
Inventor
Thomas Belliotti
Lawrence David Wise
David Juergen Wustrow
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of ID17266A publication Critical patent/ID17266A/id

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/281,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/341,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/361,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
IDP971778A 1996-05-29 1997-05-28 Antagonis antagonis reseptor d4 dopamin benzoksazinon ID17266A (id)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1838396P 1996-05-29 1996-05-29
US4020897P 1997-03-06 1997-03-06

Publications (1)

Publication Number Publication Date
ID17266A true ID17266A (id) 1997-12-18

Family

ID=26691052

Family Applications (1)

Application Number Title Priority Date Filing Date
IDP971778A ID17266A (id) 1996-05-29 1997-05-28 Antagonis antagonis reseptor d4 dopamin benzoksazinon

Country Status (36)

Country Link
EP (1) EP0906294B1 (ro)
JP (1) JP2000511534A (ro)
KR (1) KR20000016151A (ro)
CN (1) CN1074764C (ro)
AR (1) AR008372A1 (ro)
AT (1) ATE231846T1 (ro)
AU (1) AU731104B2 (ro)
BG (1) BG64049B1 (ro)
BR (1) BR9709630A (ro)
CA (1) CA2253406A1 (ro)
CO (1) CO4940505A1 (ro)
CZ (1) CZ384698A3 (ro)
DE (1) DE69718786T2 (ro)
DK (1) DK0906294T3 (ro)
EA (1) EA001486B1 (ro)
EE (1) EE03686B1 (ro)
ES (1) ES2191180T3 (ro)
GE (1) GEP20012389B (ro)
HN (1) HN1997000075A (ro)
HR (1) HRP970301B1 (ro)
HU (1) HUP9903758A3 (ro)
ID (1) ID17266A (ro)
IL (1) IL126895A (ro)
NO (1) NO312296B1 (ro)
NZ (1) NZ332737A (ro)
PA (1) PA8431101A1 (ro)
PE (1) PE69398A1 (ro)
PL (1) PL330195A1 (ro)
PT (1) PT906294E (ro)
RO (1) RO120845B1 (ro)
SI (1) SI0906294T1 (ro)
SK (1) SK282703B6 (ro)
SV (1) SV1997000047A (ro)
TW (1) TW542833B (ro)
UY (1) UY24569A1 (ro)
WO (1) WO1997045419A1 (ro)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6177422B1 (en) 1996-05-29 2001-01-23 Warner-Lambert Company Benzoxazinone dopamine D4 receptor antagonists
GB9801392D0 (en) * 1998-01-22 1998-03-18 Smithkline Beecham Plc Novel compounds
EP1089990A1 (en) * 1998-06-30 2001-04-11 Neurogen Corporation 1-(benzothiazol-2-yl)-4-(1-phenylmethyl)piperazines: dopamine receptor subtype specific ligands
US6177566B1 (en) 1998-06-30 2001-01-23 Neurogen Corporation 6-(4-arylalkylpiperazin-1-yl) benzodioxane and 6-(4-arylalkylpiperazin-1-yl) chromane derivatives: dopamine receptor subtype specific ligands
CA2336089A1 (en) * 1998-06-30 2000-01-06 Neurogen Corporation 6-(4-arylalkylpiperazin-1-yl)benzodioxane and 6-(4-arylalkylpiperazin-1-yl)chromane derivatives: dopamine receptor subtype specific ligands
US6291463B1 (en) 1998-06-30 2001-09-18 Neurogen Corporation 1-(Benzothiazol-2-yl)-4-(1-phenylmethyl) piperazines: dopamine receptor subtype specific ligands
DE19844291A1 (de) 1998-09-18 2000-03-23 Schering Ag Benzoxazin- und Benzothiazin-Derivate und deren Verwendung in Arzneimitteln
GB9912411D0 (en) 1999-05-28 1999-07-28 Pfizer Ltd Compounds useful in therapy
CN1478092A (zh) * 2000-10-26 2004-02-25 ʷ 苯并噁嗪酮衍生物及其制备和应用
GB0203804D0 (en) 2002-02-18 2002-04-03 Glaxo Group Ltd Compounds
GB0209244D0 (en) * 2002-04-23 2002-06-05 Glaxo Group Ltd Compounds
GB0227240D0 (en) * 2002-11-21 2002-12-31 Glaxo Group Ltd Compounds
ES2232292B1 (es) * 2003-07-30 2006-11-01 Laboratorios Del Dr. Esteve, S.A. Compuestos sulfonamidicos derivados de benzoxazinona, su preparacion y uso como medicamentos.
CN100455573C (zh) * 2005-11-11 2009-01-28 华东理工大学 一种制备1,4-苯并噁唑嗪-3-酮化合物的微波合成方法
KR200482995Y1 (ko) 2015-08-19 2017-03-23 이현진 물 공급부를 구비하는 얼음 트레이
AU2022261029A1 (en) * 2021-04-23 2023-10-19 Jiangsu Hansoh Pharmaceutical Group Co., Ltd. Heterocyclic derivative inhibitor and preparation method therefor and application thereof
AU2023235233A1 (en) 2022-03-14 2024-09-12 Slap Pharmaceuticals Llc Multicyclic compounds
CN119487027A (zh) * 2022-04-28 2025-02-18 宁波新湾科技发展有限公司 作为parp1抑制剂的化合物
CN117903159A (zh) * 2022-12-30 2024-04-19 成都硕德药业有限公司 一种内酰胺类衍生物、其制备方法及用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4613598A (en) * 1984-03-13 1986-09-23 Mitsubishi Chemical Industries Limited Piperazine derivatives and their acid addition salts
EP0233728A1 (en) * 1986-02-11 1987-08-26 Takeda Chemical Industries, Ltd. 1,4-Benzoxazine derivatives their production and use
EP0654023B1 (en) * 1992-08-06 1998-09-16 Smithkline Beecham Plc 5-(2-oxyphenyl)-pyrrole derivatives as dopamine d3 receptor antagonists

Also Published As

Publication number Publication date
PL330195A1 (en) 1999-04-26
CN1074764C (zh) 2001-11-14
BG102959A (en) 1999-08-31
EP0906294B1 (en) 2003-01-29
HUP9903758A3 (en) 2000-07-28
DK0906294T3 (da) 2003-05-05
EE9800417A (et) 1999-06-15
EP0906294A1 (en) 1999-04-07
SV1997000047A (es) 1998-08-13
GEP20012389B (en) 2001-03-25
HN1997000075A (es) 1997-07-30
SK282703B6 (sk) 2002-11-06
HUP9903758A2 (hu) 2000-06-28
AR008372A1 (es) 2000-01-19
TW542833B (en) 2003-07-21
EA001486B1 (ru) 2001-04-23
ATE231846T1 (de) 2003-02-15
UY24569A1 (es) 2001-08-27
KR20000016151A (ko) 2000-03-25
CO4940505A1 (es) 2000-07-24
DE69718786T2 (de) 2003-10-23
IL126895A0 (en) 1999-09-22
HK1019737A1 (en) 2000-02-25
HRP970301B1 (en) 2002-08-31
AU731104B2 (en) 2001-03-22
SI0906294T1 (en) 2003-04-30
SK162798A3 (en) 1999-06-11
IL126895A (en) 2001-06-14
NO985531D0 (no) 1998-11-27
RO120845B1 (ro) 2006-08-30
PE69398A1 (es) 1998-12-02
BG64049B1 (bg) 2003-11-28
NO985531L (no) 1998-11-27
AU3072797A (en) 1998-01-05
CZ384698A3 (cs) 1999-03-17
JP2000511534A (ja) 2000-09-05
PA8431101A1 (es) 2001-12-14
EA199800987A1 (ru) 1999-06-24
NO312296B1 (no) 2002-04-22
CN1219930A (zh) 1999-06-16
CA2253406A1 (en) 1997-12-04
WO1997045419A1 (en) 1997-12-04
NZ332737A (en) 2000-06-23
DE69718786D1 (de) 2003-03-06
BR9709630A (pt) 1999-08-10
EE03686B1 (et) 2002-04-15
ES2191180T3 (es) 2003-09-01
PT906294E (pt) 2003-06-30
HRP970301A2 (en) 1998-04-30

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