ID21358A - Konjugat yang berguna dalam pengobatan kanker prostat - Google Patents

Konjugat yang berguna dalam pengobatan kanker prostat

Info

Publication number
ID21358A
ID21358A IDW990259A ID990259A ID21358A ID 21358 A ID21358 A ID 21358A ID W990259 A IDW990259 A ID W990259A ID 990259 A ID990259 A ID 990259A ID 21358 A ID21358 A ID 21358A
Authority
ID
Indonesia
Prior art keywords
treatment
prostate cancer
consequent use
consequent
prostate
Prior art date
Application number
IDW990259A
Other languages
English (en)
Indonesian (id)
Inventor
Victor M Garsky
Dong-Mei Feng
Deborah Defeo-Jones
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9626309.0A external-priority patent/GB9626309D0/en
Priority claimed from GBGB9718160.6A external-priority patent/GB9718160D0/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of ID21358A publication Critical patent/ID21358A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/65—Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Plant Substances (AREA)
IDW990259A 1996-10-30 1997-10-27 Konjugat yang berguna dalam pengobatan kanker prostat ID21358A (id)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US2922496P 1996-10-30 1996-10-30
GBGB9626309.0A GB9626309D0 (en) 1996-12-18 1996-12-18 Conjugates useful in the treatment of prostate cancer
US4292197P 1997-04-04 1997-04-04
GBGB9718160.6A GB9718160D0 (en) 1997-08-28 1997-08-28 Conjugates useful in the treatment of prostate cancer

Publications (1)

Publication Number Publication Date
ID21358A true ID21358A (id) 1999-05-27

Family

ID=27451580

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW990259A ID21358A (id) 1996-10-30 1997-10-27 Konjugat yang berguna dalam pengobatan kanker prostat

Country Status (31)

Country Link
EP (1) EP0942754B1 (de)
JP (1) JP2000509407A (de)
KR (1) KR100508199B1 (de)
AR (1) AR008907A1 (de)
AT (1) ATE239509T1 (de)
AU (1) AU726434B2 (de)
BG (1) BG64768B1 (de)
BR (1) BR9712589A (de)
CA (1) CA2268738A1 (de)
CO (1) CO4930281A1 (de)
CZ (1) CZ155599A3 (de)
DE (1) DE69721810T2 (de)
DK (1) DK0942754T3 (de)
DZ (1) DZ2333A1 (de)
EA (1) EA002066B1 (de)
EE (1) EE03858B1 (de)
ES (1) ES2196374T3 (de)
HR (1) HRP970566A2 (de)
HU (1) HUP0000651A3 (de)
ID (1) ID21358A (de)
IL (1) IL129356A0 (de)
IS (1) IS5025A (de)
NO (1) NO992069L (de)
PE (1) PE17399A1 (de)
PL (1) PL333004A1 (de)
PT (1) PT942754E (de)
SK (1) SK57399A3 (de)
TR (1) TR199901485T2 (de)
TW (1) TW425286B (de)
WO (1) WO1998018493A2 (de)
YU (1) YU21399A (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1036093A1 (de) * 1997-12-02 2000-09-20 Merck & Co., Inc. Konjugate zur verwendung in der behandlung von prostatakrebs
CA2238257A1 (en) * 1998-05-22 1999-11-22 Universite De Montreal Endocytosis of amf-r and uses thereof in cancer therapy
EP1098666B1 (de) * 1998-07-17 2013-01-16 The United States of America, represented by the Secretary, Department of Health and Human Services Wasserlösliche arzneimittel und deren herstellungsmethode
US6174858B1 (en) 1998-11-17 2001-01-16 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
JP2003518000A (ja) * 1998-12-11 2003-06-03 コールター ファーマシューティカル,インコーポレイティド プロドラッグ化合物およびその調製方法
GB9924759D0 (en) 1999-10-19 1999-12-22 Merck Sharp & Dohme Process for preparing peptide intermediates
CA2388700A1 (en) 1999-10-19 2001-04-26 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
EP1228089A2 (de) * 1999-10-27 2002-08-07 Merck & Co., Inc. Salzform eines konjugates zur behandlung von prostatakrebs
AU4583601A (en) * 2000-03-15 2001-09-24 Du Pont Pharm Co Peptidase-cleavable, targeted antineoplastic drugs and their therapeutic use
EP2316468A1 (de) * 2002-02-22 2011-05-04 Shire LLC Abgabesystem und Verfahren zum Schutz und zur Verabreichung von Dextroamphetamin
US20050187147A1 (en) * 2003-09-22 2005-08-25 Newman Michael J. Compositions and methods for increasing drug efficiency
CN100372862C (zh) * 2003-11-05 2008-03-05 天津和美生物技术有限公司 具有抗癌活性的阿霉素衍生物及其制备方法和应用
US8518891B2 (en) * 2006-11-29 2013-08-27 Longqin Hu Chemotherapeutic conjugates and methods of use
CN101225094A (zh) * 2007-01-18 2008-07-23 天津和美生物技术有限公司 具有抗癌活性的蒽醌四环类化合物
CA2754846C (en) * 2009-03-09 2015-05-12 Ktb Tumorforschungsgesellschaft Mbh Prostate-specific antigen cleavable prodrugs
WO2012123755A1 (en) 2011-03-17 2012-09-20 The University Of Birmingham Re-directed immunotherapy
KR102438072B1 (ko) 2012-01-12 2022-08-31 예일 유니버시티 E3 유비퀴틴 리가아제에 의한 표적 단백질 및 다른 폴리펩티드의 증진된 분해를 위한 화합물 및 방법
GB201203442D0 (en) 2012-02-28 2012-04-11 Univ Birmingham Immunotherapeutic molecules and uses
GB201311891D0 (en) 2013-07-03 2013-08-14 Glaxosmithkline Ip Dev Ltd Novel compound
GB201311888D0 (en) 2013-07-03 2013-08-14 Glaxosmithkline Ip Dev Ltd Novel compounds
US20180228907A1 (en) 2014-04-14 2018-08-16 Arvinas, Inc. Cereblon ligands and bifunctional compounds comprising the same
AU2016215604B2 (en) 2015-02-02 2020-08-13 The University Of Birmingham Targeting moiety peptide epitope complexes having a plurality of T-cell epitopes
HUE054131T2 (hu) 2015-11-19 2021-08-30 Revitope Ltd Funkcionális ellenanyag-fragmens-komplementáció nemkívánatos sejtek elpusztítására szolgáló kétkomponensû rendszerben
AU2021405744A1 (en) 2020-12-22 2023-08-03 Cobiores Nv Compounds comprising a tetrapeptidic moiety
WO2022167664A1 (en) 2021-02-07 2022-08-11 Cobiores Nv Compounds comprising a tetrapeptidic moiety

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6143864A (en) * 1994-06-28 2000-11-07 Merck & Co., Inc. Peptides
US5866679A (en) * 1994-06-28 1999-02-02 Merck & Co., Inc. Peptides
EP0855910A4 (de) * 1995-10-18 2000-07-05 Merck & Co Inc Verwendbare konjugate zur behandlung der gutartigen prostatehyperplasie

Also Published As

Publication number Publication date
TW425286B (en) 2001-03-11
HRP970566A2 (en) 1998-08-31
EP0942754B1 (de) 2003-05-07
PT942754E (pt) 2003-08-29
DE69721810T2 (de) 2004-03-11
HK1024876A1 (en) 2000-10-27
CO4930281A1 (es) 2000-06-27
KR20000052970A (ko) 2000-08-25
HUP0000651A2 (hu) 2000-06-28
BR9712589A (pt) 1999-10-26
NO992069D0 (no) 1999-04-29
EE03858B1 (et) 2002-10-15
IL129356A0 (en) 2000-02-17
SK57399A3 (en) 2000-01-18
WO1998018493A2 (en) 1998-05-07
EE9900179A (et) 1999-12-15
EA199900428A1 (ru) 2000-02-28
YU21399A (sh) 2000-03-21
ATE239509T1 (de) 2003-05-15
HUP0000651A3 (en) 2001-12-28
DZ2333A1 (fr) 2002-12-28
JP2000509407A (ja) 2000-07-25
AR008907A1 (es) 2000-02-23
EA002066B1 (ru) 2001-12-24
CZ155599A3 (cs) 1999-10-13
AU5149798A (en) 1998-05-22
ES2196374T3 (es) 2003-12-16
DE69721810D1 (de) 2003-06-12
AU726434B2 (en) 2000-11-09
EP0942754A2 (de) 1999-09-22
KR100508199B1 (ko) 2005-08-17
IS5025A (is) 1999-04-13
PL333004A1 (en) 1999-11-08
BG103436A (en) 2000-04-28
PE17399A1 (es) 1999-02-20
DK0942754T3 (da) 2003-08-04
NO992069L (no) 1999-06-30
WO1998018493A3 (en) 1998-07-23
BG64768B1 (bg) 2006-03-31
TR199901485T2 (xx) 1999-08-23
CA2268738A1 (en) 1998-05-07

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