ID21981A - Inhibitor-inhibitor sintasis nitrik oksida - Google Patents

Inhibitor-inhibitor sintasis nitrik oksida

Info

Publication number
ID21981A
ID21981A IDW990672A ID990672A ID21981A ID 21981 A ID21981 A ID 21981A ID W990672 A IDW990672 A ID W990672A ID 990672 A ID990672 A ID 990672A ID 21981 A ID21981 A ID 21981A
Authority
ID
Indonesia
Prior art keywords
oxida
synthesis
synthetic inhibitors
inhibitors
synthetic
Prior art date
Application number
IDW990672A
Other languages
English (en)
Indonesian (id)
Inventor
Richard Mansfield Beams
Martin James Drysdale
Karl Witold Franzmann
Anthony Joseph Frend
Harold Francis Hodson
Richard Graham Knowles
Daryl David Rees
David Alan Sawyer
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ID21981A publication Critical patent/ID21981A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
    • C07C323/59—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton with acylated amino groups bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/57—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C323/58—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups with amino groups bound to the carbon skeleton
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Safety Valves (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IDW990672A 1997-01-13 1998-01-09 Inhibitor-inhibitor sintasis nitrik oksida ID21981A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US78340297A 1997-01-13 1997-01-13

Publications (1)

Publication Number Publication Date
ID21981A true ID21981A (id) 1999-08-19

Family

ID=25129141

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW990672A ID21981A (id) 1997-01-13 1998-01-09 Inhibitor-inhibitor sintasis nitrik oksida

Country Status (34)

Country Link
EP (1) EP0958277B1 (no)
JP (1) JP3251301B2 (no)
KR (1) KR20000070070A (no)
CN (1) CN1149190C (no)
AP (1) AP1204A (no)
AR (1) AR011069A1 (no)
AT (1) ATE209183T1 (no)
AU (1) AU723095B2 (no)
BR (1) BR9806870B1 (no)
CA (1) CA2277877C (no)
CO (1) CO4950524A1 (no)
CY (1) CY2263B1 (no)
CZ (1) CZ293099B6 (no)
DE (1) DE69803272T2 (no)
DK (1) DK0958277T3 (no)
EA (1) EA002033B1 (no)
EE (1) EE04013B1 (no)
ES (1) ES2168737T3 (no)
HU (1) HU226241B1 (no)
ID (1) ID21981A (no)
IL (1) IL130551A (no)
IS (1) IS1847B (no)
MY (1) MY117948A (no)
NO (1) NO312192B1 (no)
NZ (1) NZ336379A (no)
PE (1) PE44599A1 (no)
PL (1) PL189973B1 (no)
PT (1) PT958277E (no)
RS (1) RS49673B (no)
SK (1) SK283201B6 (no)
TR (1) TR199901680T2 (no)
TW (2) TW502010B (no)
WO (1) WO1998030537A1 (no)
ZA (1) ZA98179B (no)

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US7012098B2 (en) * 2001-03-23 2006-03-14 Pharmacia Corporation Inhibitors of inducible nitric oxide synthase for chemoprevention and treatment of cancers
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CN100460387C (zh) * 2003-03-11 2009-02-11 法马西亚公司 盐酸s-[2-[(1-亚氨基乙基)氨基]乙基]-2-甲基-l-半胱氨酸马来酸盐结晶盐
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Also Published As

Publication number Publication date
NZ336379A (en) 2001-01-26
DK0958277T3 (da) 2002-02-18
PL334368A1 (en) 2000-02-28
HUP0001539A2 (hu) 2000-11-28
CZ293099B6 (cs) 2004-02-18
BR9806870A (pt) 2000-04-18
CZ248399A3 (cs) 1999-12-15
AU6208398A (en) 1998-08-03
AR011069A1 (es) 2000-08-02
NO993429D0 (no) 1999-07-12
CY2263B1 (en) 2003-07-04
BR9806870B1 (pt) 2009-05-05
MY117948A (en) 2004-08-30
IL130551A (en) 2004-01-04
ES2168737T3 (es) 2002-06-16
EE04013B1 (et) 2003-04-15
EP0958277B1 (en) 2001-11-21
DE69803272D1 (en) 2002-02-21
DE69803272T2 (de) 2002-07-18
WO1998030537A1 (en) 1998-07-16
EE9900281A (et) 2000-02-15
NO993429L (no) 1999-07-12
HU226241B1 (en) 2008-07-28
CN1149190C (zh) 2004-05-12
KR20000070070A (ko) 2000-11-25
EP0958277A1 (en) 1999-11-24
PL189973B1 (pl) 2005-10-31
SK93399A3 (en) 2000-03-13
TW502010B (en) 2002-09-11
PT958277E (pt) 2002-05-31
IS1847B (is) 2003-02-07
EA002033B1 (ru) 2001-12-24
JP2000504041A (ja) 2000-04-04
HUP0001539A3 (en) 2003-01-28
AP1204A (en) 2003-09-15
IS5094A (is) 1999-06-25
AU723095B2 (en) 2000-08-17
CN1249744A (zh) 2000-04-05
HK1021531A1 (en) 2000-06-16
CO4950524A1 (es) 2000-09-01
PE44599A1 (es) 1999-05-05
ZA98179B (en) 1999-07-09
NO312192B1 (no) 2002-04-08
SK283201B6 (sk) 2003-03-04
JP3251301B2 (ja) 2002-01-28
TW538021B (en) 2003-06-21
EA199900532A1 (ru) 2000-08-28
ATE209183T1 (de) 2001-12-15
AP9901603A0 (en) 1999-09-30
IL130551A0 (en) 2000-06-01
RS49673B (sr) 2007-11-15
CA2277877A1 (en) 1998-07-16
YU31399A (sh) 2002-06-19
CA2277877C (en) 2008-01-08
TR199901680T2 (xx) 1999-09-21

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