ID22984A - Proses epoksidasi selektif untuk pembuatan senyawa farmasi - Google Patents

Proses epoksidasi selektif untuk pembuatan senyawa farmasi

Info

Publication number
ID22984A
ID22984A IDW990901A ID990901A ID22984A ID 22984 A ID22984 A ID 22984A ID W990901 A IDW990901 A ID W990901A ID 990901 A ID990901 A ID 990901A ID 22984 A ID22984 A ID 22984A
Authority
ID
Indonesia
Prior art keywords
pharmaceutical compounds
epoxidation process
making pharmaceutical
selective epoxidation
selective
Prior art date
Application number
IDW990901A
Other languages
English (en)
Inventor
Vinod Francis Patel
David Warren Hoard
Eric David Moher
Bryan Hurst Norman
Original Assignee
Eli Lilly And Company Cs
Univ Hawaii
Univ Wayne State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company Cs, Univ Hawaii, Univ Wayne State filed Critical Eli Lilly And Company Cs
Publication of ID22984A publication Critical patent/ID22984A/id

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D273/00Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/38Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/38Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D303/40Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by ester radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/38Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D303/46Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by amide or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cephalosporin Compounds (AREA)
IDW990901A 1997-02-26 1998-02-25 Proses epoksidasi selektif untuk pembuatan senyawa farmasi ID22984A (id)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3911497P 1997-02-26 1997-02-26
US3911697P 1997-02-26 1997-02-26

Publications (1)

Publication Number Publication Date
ID22984A true ID22984A (id) 1999-12-23

Family

ID=26715826

Family Applications (2)

Application Number Title Priority Date Filing Date
IDW990901A ID22984A (id) 1997-02-26 1998-02-25 Proses epoksidasi selektif untuk pembuatan senyawa farmasi
IDW990900D ID24527A (id) 1997-02-26 1998-02-25 Proses pembuatan senyawa-senyawa farmasi

Family Applications After (1)

Application Number Title Priority Date Filing Date
IDW990900D ID24527A (id) 1997-02-26 1998-02-25 Proses pembuatan senyawa-senyawa farmasi

Country Status (17)

Country Link
US (1) US6143909A (id)
EP (2) EP0861838A3 (id)
JP (2) JP2002513403A (id)
KR (2) KR20000075671A (id)
CN (2) CN1252788A (id)
AU (2) AU6667198A (id)
BR (2) BR9807265A (id)
CA (2) CA2281104A1 (id)
CZ (1) CZ9902998A3 (id)
EA (2) EA002547B1 (id)
ID (2) ID22984A (id)
IL (2) IL131162A0 (id)
NO (2) NO994049D0 (id)
NZ (1) NZ336918A (id)
PL (2) PL335478A1 (id)
TR (2) TR199902064T2 (id)
WO (2) WO1998038164A1 (id)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2264294A1 (en) * 1996-08-30 1998-03-05 University Of Hawai'i Process for preparing pharmaceutical compounds
CA2264557A1 (en) * 1996-09-06 1998-03-12 Eli Lilly And Company Process and novel intermediates
AU1123200A (en) * 1998-10-16 2000-05-08 Eli Lilly And Company Stereoselective process for producing antineoplastic agents
AU1930100A (en) * 1998-12-07 2000-06-26 Eli Lilly And Company Crotylboration process to produce cryptophycin compounds
AU1930200A (en) * 1998-12-07 2000-06-26 Eli Lilly And Company Crotylboration process to produce antineoplastic and antifungal agents
AU775373B2 (en) 1999-10-01 2004-07-29 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
EP1751279A4 (en) * 2004-05-05 2008-03-19 Univ Minnesota NUCLEIC ACIDS AND POLYPEPTIDES INVOLVED IN THE PREPARATION OF CRYPTOPHYCIN
CN101962323B (zh) * 2010-07-16 2013-06-05 中国人民解放军第二军医大学 2-丙烯酰x基-3-取代苯基丙酸类化合物及其用途
CN111333560B (zh) * 2020-04-13 2024-01-23 合肥工业大学 一种制备螺环β-内酰胺的方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4868208A (en) * 1988-07-15 1989-09-19 Merck & Co., Inc. Antifungal agent and method
US4946835A (en) * 1988-07-15 1990-08-07 Merck & Co., Inc. Antifungal fermentation product and method
US4845085A (en) * 1988-08-09 1989-07-04 Merck & Co., Inc. Antifungal agent
US4845086A (en) * 1988-08-09 1989-07-04 Merck & Co., Inc. Antifungal agent
JPH04504416A (ja) * 1989-02-17 1992-08-06 コセルコ・ミモトープス・ピィ・ティ・ワイ.エル・ティ・ディ. ペプチドの使用方法と合成方法
US5256802A (en) * 1990-04-03 1993-10-26 Miles Inc. Process for the production of oxiranes
NZ257077A (en) * 1992-11-06 1997-05-26 Chiron Mimotopes Pty Ltd Support for synthesis of modular polymers
GB2282384B8 (en) * 1993-08-18 1997-09-04 Europ Economic Community Drug delivery agents incorporating mitomycin
WO1995017093A1 (en) * 1993-12-21 1995-06-29 University Of Hawaii New cryptophycins
US5952298A (en) * 1993-12-21 1999-09-14 The University Of Hawaii Cryptophycins
AU723652B2 (en) * 1993-12-21 2000-08-31 University Of Hawaii New cryptophycins from synthesis
DE69516415T2 (de) * 1994-10-14 2000-09-14 Stratagene, La Jolla Porphyrin-markierung von polynukleotiden
PT826681E (pt) * 1995-03-31 2003-02-28 Nippon Chemiphar Co Derivados de acido epoxi-succinico
US5700826A (en) * 1995-06-07 1997-12-23 Ontogen Corporation 1,2,4,5-tetra substituted imidazoles as modulators of multi-drug resistance
EP0850057A4 (en) * 1995-08-30 2001-04-11 Lilly Co Eli Pharmaceutical compounds
DE69626544T2 (de) * 1995-12-22 2004-01-15 Lilly Co Eli Arzneistoffe
CN1105496C (zh) * 1996-02-07 2003-04-16 巴科曼实验室国际公司 含一种紫罗烯聚合物及十二烷胺盐的协同抗微生物组合物及其使用方法
EP0792875B1 (en) * 1996-02-27 2001-05-09 Eli Lilly And Company Cryptophycin derivatives and their use as anti-microtubule agents
WO1998008506A1 (en) * 1996-08-30 1998-03-05 Eli Lilly And Company Pharmaceutical compounds
CA2264297A1 (en) * 1996-08-30 1998-03-05 Chuan Shih Pharmaceutical compounds
PT934065E (pt) * 1996-08-30 2006-10-31 Univ Hawaii Compostos farmaceuticos
US6025506A (en) * 1997-02-21 2000-02-15 Dsm N.V. Process for preparing an optically active phenylglycidyl acid derivative
TW438787B (en) * 1997-02-27 2001-06-07 Tanabe Seiyaku Co Process for preparing optically active trans-3-substituted glycidic acid ester

Also Published As

Publication number Publication date
US6143909A (en) 2000-11-07
CZ9902998A3 (cs) 2002-10-16
AU6667298A (en) 1998-09-18
CA2281108A1 (en) 1998-09-03
CN1252788A (zh) 2000-05-10
NO994049L (no) 1999-08-23
TR199902065T2 (xx) 2000-02-21
EA199900772A1 (ru) 2000-04-24
JP2002512603A (ja) 2002-04-23
EP0861839A1 (en) 1998-09-02
WO1998038164A1 (en) 1998-09-03
PL335347A1 (en) 2000-04-25
EP0861838A3 (en) 1998-12-09
PL335478A1 (en) 2000-04-25
NZ336918A (en) 2001-11-30
AU6667198A (en) 1998-09-18
IL131162A0 (en) 2001-01-28
CN1255121A (zh) 2000-05-31
EA002547B1 (ru) 2002-06-27
KR20000075623A (ko) 2000-12-26
WO1998038158A1 (en) 1998-09-03
BR9811252A (pt) 2000-09-26
EA199900770A1 (ru) 2000-04-24
KR20000075671A (ko) 2000-12-26
NO994083L (no) 1999-10-25
TR199902064T2 (xx) 2001-10-22
JP2002513403A (ja) 2002-05-08
AU738999B2 (en) 2001-10-04
IL131205A0 (en) 2001-01-28
ID24527A (id) 2000-07-20
EP0861838A2 (en) 1998-09-02
BR9807265A (pt) 2000-05-23
NO994049D0 (no) 1999-08-23
CA2281104A1 (en) 1998-09-03
NO994083D0 (no) 1999-08-24

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