ID22984A - Proses epoksidasi selektif untuk pembuatan senyawa farmasi - Google Patents

Proses epoksidasi selektif untuk pembuatan senyawa farmasi

Info

Publication number
ID22984A
ID22984A IDW990901A ID990901A ID22984A ID 22984 A ID22984 A ID 22984A ID W990901 A IDW990901 A ID W990901A ID 990901 A ID990901 A ID 990901A ID 22984 A ID22984 A ID 22984A
Authority
ID
Indonesia
Prior art keywords
pharmaceutical compounds
epoxidation process
making pharmaceutical
selective epoxidation
selective
Prior art date
Application number
IDW990901A
Other languages
English (en)
Inventor
Vinod Francis Patel
David Warren Hoard
Eric David Moher
Bryan Hurst Norman
Original Assignee
Eli Lilly And Company Cs
Univ Hawaii
Univ Wayne State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company Cs, Univ Hawaii, Univ Wayne State filed Critical Eli Lilly And Company Cs
Publication of ID22984A publication Critical patent/ID22984A/id

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D273/00Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/38Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/38Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D303/40Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by ester radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/38Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D303/46Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by amide or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IDW990901A 1997-02-26 1998-02-25 Proses epoksidasi selektif untuk pembuatan senyawa farmasi ID22984A (id)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3911697P 1997-02-26 1997-02-26
US3911497P 1997-02-26 1997-02-26

Publications (1)

Publication Number Publication Date
ID22984A true ID22984A (id) 1999-12-23

Family

ID=26715826

Family Applications (2)

Application Number Title Priority Date Filing Date
IDW990900D ID24527A (id) 1997-02-26 1998-02-25 Proses pembuatan senyawa-senyawa farmasi
IDW990901A ID22984A (id) 1997-02-26 1998-02-25 Proses epoksidasi selektif untuk pembuatan senyawa farmasi

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IDW990900D ID24527A (id) 1997-02-26 1998-02-25 Proses pembuatan senyawa-senyawa farmasi

Country Status (17)

Country Link
US (1) US6143909A (id)
EP (2) EP0861838A3 (id)
JP (2) JP2002512603A (id)
KR (2) KR20000075623A (id)
CN (2) CN1255121A (id)
AU (2) AU738999B2 (id)
BR (2) BR9811252A (id)
CA (2) CA2281104A1 (id)
CZ (1) CZ9902998A3 (id)
EA (2) EA002547B1 (id)
ID (2) ID24527A (id)
IL (2) IL131162A0 (id)
NO (2) NO994049D0 (id)
NZ (1) NZ336918A (id)
PL (2) PL335347A1 (id)
TR (2) TR199902065T2 (id)
WO (2) WO1998038158A1 (id)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5977387A (en) * 1996-08-30 1999-11-02 Eli Lilly And Company Process for preparing pharmaceutical compounds
CA2264557A1 (en) * 1996-09-06 1998-03-12 Eli Lilly And Company Process and novel intermediates
AU1123200A (en) * 1998-10-16 2000-05-08 Eli Lilly And Company Stereoselective process for producing antineoplastic agents
AU1930200A (en) * 1998-12-07 2000-06-26 Eli Lilly And Company Crotylboration process to produce antineoplastic and antifungal agents
AU1930100A (en) * 1998-12-07 2000-06-26 Eli Lilly And Company Crotylboration process to produce cryptophycin compounds
AU775373B2 (en) 1999-10-01 2004-07-29 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
WO2005116200A2 (en) 2004-05-05 2005-12-08 Regents Of The University Of Minnesota Nucleic acids and polypeptides involved in the production of cryptophycin
CN101962323B (zh) * 2010-07-16 2013-06-05 中国人民解放军第二军医大学 2-丙烯酰x基-3-取代苯基丙酸类化合物及其用途
CN111333560B (zh) * 2020-04-13 2024-01-23 合肥工业大学 一种制备螺环β-内酰胺的方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4946835A (en) * 1988-07-15 1990-08-07 Merck & Co., Inc. Antifungal fermentation product and method
US4868208A (en) * 1988-07-15 1989-09-19 Merck & Co., Inc. Antifungal agent and method
US4845086A (en) * 1988-08-09 1989-07-04 Merck & Co., Inc. Antifungal agent
US4845085A (en) * 1988-08-09 1989-07-04 Merck & Co., Inc. Antifungal agent
ATE123780T1 (de) * 1989-02-17 1995-06-15 Chiron Mimotopes Pty Ltd Verfahren zur verwendung und herstellung von peptiden.
US5256802A (en) * 1990-04-03 1993-10-26 Miles Inc. Process for the production of oxiranes
AU680450B2 (en) * 1992-11-06 1997-07-31 Mimotopes Pty Ltd Support for the synthesis of modular polymers
GB2282384B8 (en) * 1993-08-18 1997-09-04 Europ Economic Community Drug delivery agents incorporating mitomycin
US5952298A (en) * 1993-12-21 1999-09-14 The University Of Hawaii Cryptophycins
JPH09510436A (ja) * 1993-12-21 1997-10-21 ユニバーシティー オブ ハワイ 新規なクリプトフィシン類
DE69516415T2 (de) * 1994-10-14 2000-09-14 Stratagene, La Jolla Porphyrin-markierung von polynukleotiden
AP737A (en) * 1995-03-07 1999-03-15 Univ Hawaii New cryptophycins from synthesis.
EP0826681B1 (en) * 1995-03-31 2002-10-09 Nippon Chemiphar Co., Ltd. Epoxysuccinic acid derivatives
US5700826A (en) * 1995-06-07 1997-12-23 Ontogen Corporation 1,2,4,5-tetra substituted imidazoles as modulators of multi-drug resistance
BR9610214A (pt) * 1995-08-30 1999-06-15 Lilly Co Eli Compostos farmacéuticos
EP0869786B1 (en) * 1995-12-22 2003-03-05 Eli Lilly And Company Pharmaceutical compounds
AU724312B2 (en) * 1996-02-07 2000-09-14 Buckman Laboratories International, Inc. Synergistic antimicrobial compositions containing an ionene polymer and a salt of dodecylamine and methods of using the same
ATE201018T1 (de) * 1996-02-27 2001-05-15 Lilly Co Eli Cryptophycinderivate und ihre verwendung als antimikrotubuli mittel
AU722492B2 (en) * 1996-08-30 2000-08-03 University Of Hawaii Pharmaceutical compounds
AU4169897A (en) * 1996-08-30 1998-03-19 Eli Lilly And Company Pharmaceutical compounds
EP0957912A1 (en) * 1996-08-30 1999-11-24 Eli Lilly And Company Pharmaceutical compounds
US6025506A (en) * 1997-02-21 2000-02-15 Dsm N.V. Process for preparing an optically active phenylglycidyl acid derivative
IL123352A0 (en) * 1997-02-27 1998-09-24 Tanabe Seiyaku Co Process for preparing an optically active trans-3-substituted glycidic acid ester

Also Published As

Publication number Publication date
CN1252788A (zh) 2000-05-10
AU6667298A (en) 1998-09-18
EA002547B1 (ru) 2002-06-27
IL131162A0 (en) 2001-01-28
AU738999B2 (en) 2001-10-04
EP0861839A1 (en) 1998-09-02
PL335347A1 (en) 2000-04-25
NO994083L (no) 1999-10-25
TR199902064T2 (xx) 2001-10-22
CA2281108A1 (en) 1998-09-03
BR9807265A (pt) 2000-05-23
AU6667198A (en) 1998-09-18
US6143909A (en) 2000-11-07
CN1255121A (zh) 2000-05-31
KR20000075623A (ko) 2000-12-26
NO994049L (no) 1999-08-23
BR9811252A (pt) 2000-09-26
EA199900772A1 (ru) 2000-04-24
ID24527A (id) 2000-07-20
NO994083D0 (no) 1999-08-24
NZ336918A (en) 2001-11-30
EA199900770A1 (ru) 2000-04-24
CA2281104A1 (en) 1998-09-03
PL335478A1 (en) 2000-04-25
JP2002512603A (ja) 2002-04-23
JP2002513403A (ja) 2002-05-08
NO994049D0 (no) 1999-08-23
EP0861838A2 (en) 1998-09-02
KR20000075671A (ko) 2000-12-26
WO1998038158A1 (en) 1998-09-03
TR199902065T2 (xx) 2000-02-21
CZ9902998A3 (cs) 2002-10-16
IL131205A0 (en) 2001-01-28
WO1998038164A1 (en) 1998-09-03
EP0861838A3 (en) 1998-12-09

Similar Documents

Publication Publication Date Title
ID17271A (id) Proses untuk pengubahan etilbenzena
TR199600792A2 (tr) Dihaloazolopirimidinlerin hazirlanmasina yönelik proses.
ID19704A (id) Proses untuk memproduksi senyawa karbonil
ID26102A (id) Proses pembuatan senyawa-senyawa stilbena
ID27308A (id) Proses aksidasi
ID28724A (id) Proses untuk memproduksi sikloalkanon
ID26281A (id) Proses transesterifikasi menggunakan katalis-katalis senyawa lantanum
ID20274A (id) Proses untuk memproduksi diamina
ID22641A (id) Proses pembuatan e-kaprolaktam
ID16914A (id) Proses untuk pembuatan aldehida
ID20304A (id) Proses pembuatan kertas
ID22662A (id) Proses pemurnian kaprolaktam
ID28601A (id) Proses penyiapan senyawa-senyawa 1,4-dihidropiridin
ID29787A (id) Proses untuk memproduksi cairan kaya-metana
BR9607626A (pt) Novos compostos farmacéuticos de naftila
ID22984A (id) Proses epoksidasi selektif untuk pembuatan senyawa farmasi
ID24977A (id) Proses untuk membuat senyawa nitro aromatik
ID22906A (id) Proses untuk memurnikan siloksana
ID22222A (id) Proses pembuatan tiazolidinadiona tersubstitusi
NO995851D0 (no) Fremstillingsfremgangsmåte for isoksasolidinedion forbindelse
ID23155A (id) Proses pembuatan eprosartan
ID24830A (id) Proses untuk pengolahan laktam
ID28625A (id) Proses untuk modifikasi pektin secara enzimatik
ID23181A (id) Proses pembuatan eprosartan
ID18917A (id) Proses untuk sintesis benzotiofena