ID23991A - Turunan-turunan sulfonil - Google Patents

Turunan-turunan sulfonil

Info

Publication number
ID23991A
ID23991A IDW20000598A ID982005A ID23991A ID 23991 A ID23991 A ID 23991A ID W20000598 A IDW20000598 A ID W20000598A ID 982005 A ID982005 A ID 982005A ID 23991 A ID23991 A ID 23991A
Authority
ID
Indonesia
Prior art keywords
group
hydrogen atom
independently represents
chem
salt
Prior art date
Application number
IDW20000598A
Other languages
English (en)
Indonesian (id)
Inventor
Syozo Kobayashi
Satoshi Komoriya
Masayuki Ito
Tsutomu Nagata
Akiyoshi Mochizuki
Noriyasu Haginoya
Takayasu Nagahara
Haru Hiko Horino
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Publication of ID23991A publication Critical patent/ID23991A/id

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    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Lubricants (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Dry Shavers And Clippers (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyridine Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IDW20000598A 1997-09-30 1998-09-30 Turunan-turunan sulfonil ID23991A (id)

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AT (1) ATE314347T1 (de)
AU (1) AU9280698A (de)
BR (1) BR9815377A (de)
CA (1) CA2304285A1 (de)
DE (1) DE69833036T2 (de)
DK (1) DK1031563T3 (de)
ES (1) ES2255733T3 (de)
ID (1) ID23991A (de)
IL (1) IL135180A0 (de)
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Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6525042B1 (en) * 1997-09-30 2003-02-25 Daiichi Pharmaceutical Co., Ltd. Sulfonyl derivatives
WO1999037304A1 (en) * 1998-01-27 1999-07-29 Aventis Pharmaceuticals Products Inc. SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS
GB9809350D0 (en) * 1998-05-02 1998-07-01 Zeneca Ltd Novel salt
GB9809349D0 (en) * 1998-05-02 1998-07-01 Zeneca Ltd Heterocyclic derivatives
AU5196399A (en) * 1998-08-11 2000-03-06 Daiichi Pharmaceutical Co., Ltd. Novel sulfonyl derivatives
ES2217879T3 (es) 1998-12-24 2004-11-01 Eli Lilly And Company Amidas heterociclicas.
IL146309A (en) * 1999-05-21 2008-03-20 Scios Inc Derivatives of the indole type and pharmaceutical preparations containing them as inhibitors of kinase p38
JP2001294572A (ja) * 2000-02-09 2001-10-23 Dai Ichi Seiyaku Co Ltd 新規スルホニル誘導体
WO2001062763A1 (en) * 2000-02-25 2001-08-30 Daiichi Pharmaceutical Co., Ltd. Method for inhibiting trypsin-type serine proteases
TWI288745B (en) * 2000-04-05 2007-10-21 Daiichi Seiyaku Co Ethylenediamine derivatives
EP1307444B1 (de) 2000-07-27 2007-10-03 Eli Lilly And Company Substituierte heterocyclische amide
EP1322610A2 (de) * 2000-09-29 2003-07-02 Millennium Pharmaceuticals, Inc. Faktor xa inhibitoren abgeleitet von piperazin
DE60128936T2 (de) * 2000-10-12 2008-04-10 Merck & Co, Inc. Aza- und polyaza-naphthalenylcarbonsäureamide als hiv-integrase-hemmer
CA2425625A1 (en) * 2000-10-12 2002-07-18 Merck & Co., Inc. Aza-and polyaza-naphthalenyl carboxamides useful as hiv integrase inhibitors
WO2002030931A2 (en) 2000-10-12 2002-04-18 Merck & Co., Inc. Aza- and polyaza-naphthalenyl carboxamides useful as hiv integrase inhibitors
CA2440389A1 (en) * 2001-03-09 2002-10-03 Ortho-Mcneil Pharmaceutical, Inc. Aminopyrrolidine sulfonamides as serine protease inhibitors
GB0114005D0 (en) 2001-06-08 2001-08-01 Glaxo Group Ltd Chemical compounds
GB0114004D0 (en) 2001-06-08 2001-08-01 Glaxo Group Ltd Chemical compounds
RU2319699C2 (ru) * 2001-06-20 2008-03-20 Дайити Санкио Компани, Лимитед Производные диаминов
US7365205B2 (en) 2001-06-20 2008-04-29 Daiichi Sankyo Company, Limited Diamine derivatives
GB0127568D0 (en) 2001-11-16 2002-01-09 Glaxo Group Ltd Chemical compounds
EP1456175A1 (de) 2001-12-07 2004-09-15 Eli Lilly And Company Substituierte heterozyklische karboxamide mit antithrombotischer aktivität
US7354932B2 (en) 2001-12-21 2008-04-08 Anormed, Inc. Chemokine receptor binding heterocyclic compounds with enhanced efficacy
EP1569912B1 (de) 2002-12-03 2015-04-29 Pharmacyclics, Inc. 2-(2-hydroxybiphenyl-3-yl)-1h-benzoimidazole-5-carboxamidinderivate als faktor vii-a hemmer
WO2003077857A2 (en) * 2002-03-15 2003-09-25 Merck & Co., Inc. N-(substituted benzyl)-8-hydroxy-1,6-naphthyridine-7- carboxamides useful as hiv integrase inhibitors
WO2003104257A2 (en) * 2002-05-22 2003-12-18 Smithkline Beecham Corporation Protease inhibitors
GB0228533D0 (en) * 2002-12-06 2003-01-15 Glaxo Group Ltd Crystalline form
MXPA05006989A (es) * 2002-12-25 2005-09-22 Daiichi Seiyaku Co Derivados de diamina.
EP1601251B1 (de) 2003-02-13 2014-11-12 Wellstat Therapeutics Corporation Verbindungen zur behandlung von stoffwechselstörungen
US20050119266A1 (en) * 2003-10-01 2005-06-02 Yan Shi Pyrrolidine and piperidine derivatives as factor Xa inhibitors
US20090253908A1 (en) * 2004-03-11 2009-10-08 Glaxo Group Limited Novel m3 muscarinic acetylchoine receptor antagonists
PT2361924E (pt) 2004-09-09 2014-03-13 Teva Pharma Processo para a preparação de misturas de acetato de glatirâmero trifluoroacetiílico utilizando ácido bromídrico purificado
TW200619206A (en) * 2004-09-29 2006-06-16 Anormed Inc Chemokine-binding heterocyclic compound salts, and methods of use thereof
TW200630337A (en) * 2004-10-14 2006-09-01 Euro Celtique Sa Piperidinyl compounds and the use thereof
WO2007008145A1 (en) * 2005-07-08 2007-01-18 Astrazeneca Ab Heterocyclic sulfonamide derivatives as inhibitors of factor xa
JP2009524686A (ja) 2006-01-25 2009-07-02 ウェルスタット セラピューティクス コーポレイション 代謝障害を処置するための化合物
WO2007087505A2 (en) 2006-01-25 2007-08-02 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
US20090176885A1 (en) 2006-02-02 2009-07-09 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
WO2007110449A1 (en) * 2006-03-29 2007-10-04 Euro-Celtique S.A. Benzenesulfonamide compounds and their use
WO2007118853A1 (en) * 2006-04-13 2007-10-25 Euro-Celtique S.A. Benzenesulfonamide compounds and their use as blockers of calcium channels
TW200812963A (en) * 2006-04-13 2008-03-16 Euro Celtique Sa Benzenesulfonamide compounds and the use thereof
US8017612B2 (en) 2006-04-18 2011-09-13 Japan Tobacco Inc. Piperazine compound and use thereof as a HCV polymerase inhibitor
US8399486B2 (en) * 2007-04-09 2013-03-19 Purdue Pharma L.P. Benzenesulfonyl compounds and the use thereof
US8765736B2 (en) * 2007-09-28 2014-07-01 Purdue Pharma L.P. Benzenesulfonamide compounds and the use thereof
EP2345643A1 (de) * 2009-12-29 2011-07-20 Polichem S.A. Neue tertiäre 8-Hydroxychinolin-7-Carboxamidederivate und deren Verwendungen
US11357742B2 (en) 2015-12-14 2022-06-14 X4 Pharmaceuticals, Inc. Methods for treating cancer
ES2907489T3 (es) 2015-12-14 2022-04-25 X4 Pharmaceuticals Inc Métodos para el tratamiento del cáncer
ES2935834T3 (es) 2015-12-22 2023-03-10 X4 Pharmaceuticals Inc Métodos para tratar enfermedad de inmunodeficiencia
US11337969B2 (en) 2016-04-08 2022-05-24 X4 Pharmaceuticals, Inc. Methods for treating cancer
JP7054529B2 (ja) 2016-06-21 2022-04-14 エックス4 ファーマシューティカルズ, インコーポレイテッド Cxcr4阻害剤およびその使用
US11332470B2 (en) 2016-06-21 2022-05-17 X4 Pharmaceuticals, Inc. CXCR4 inhibitors and uses thereof
US10988465B2 (en) 2016-06-21 2021-04-27 X4 Pharmaceuticals, Inc. CXCR4 inhibitors and uses thereof
US10548889B1 (en) 2018-08-31 2020-02-04 X4 Pharmaceuticals, Inc. Compositions of CXCR4 inhibitors and methods of preparation and use
WO2021183650A1 (en) 2020-03-10 2021-09-16 X4 Pharmaceuticals, Inc. Methods for treating neutropenia

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4121947A1 (de) 1991-07-03 1993-01-07 Basf Ag 2-(3-(4-amidino-phenyl))-propionsaeurederivate, ihre herstellung und verwendung
IL115420A0 (en) 1994-09-26 1995-12-31 Zeneca Ltd Aminoheterocyclic derivatives
US5731315A (en) 1995-06-07 1998-03-24 Rhone-Poulenc Rorer Pharmaceuticals Inc. Substituted sulfonic acid n- (aminoiminomethyl)phenylalkyl!-azaheterocyclamide compounds
US5612353A (en) 1995-06-07 1997-03-18 Rhone-Poulenc Rorer Pharmaceuticals Inc. Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N-[(aminoiminomethyl)phenylalkyl]-azaheterocyclylamide compounds
GB9516709D0 (en) * 1995-08-15 1995-10-18 Zeneca Ltd Medicament
GB9602294D0 (en) 1996-02-05 1996-04-03 Zeneca Ltd Heterocyclic compounds
PL331599A1 (en) 1996-08-14 1999-08-02 Zeneca Ltd Substituted derivatives of pyrimidine and their pharmaceutical application
UA56197C2 (uk) 1996-11-08 2003-05-15 Зенека Лімітед Гетероциклічні похідні
JP4223560B2 (ja) * 1996-12-13 2009-02-12 アヴェンティス ファーマシューティカルズ インコーポレイテッド スルホン酸又はスルホニルアミノn−(ヘテロアラルキル)アザヘテロシクリルアミド化合物
DE69835430T2 (de) * 1997-05-30 2007-03-08 Takeda Pharmaceutical Co. Ltd. Sulfonamidderivate, ihre herstellung und verwendung
US6525042B1 (en) * 1997-09-30 2003-02-25 Daiichi Pharmaceutical Co., Ltd. Sulfonyl derivatives
DE19743435A1 (de) * 1997-10-01 1999-04-08 Merck Patent Gmbh Benzamidinderivate
WO1999037304A1 (en) 1998-01-27 1999-07-29 Aventis Pharmaceuticals Products Inc. SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS
CA2317017A1 (en) * 1998-02-05 1999-08-12 Takeda Chemical Industries, Ltd. Sulfonamide derivatives, their production and use
GB9809349D0 (en) 1998-05-02 1998-07-01 Zeneca Ltd Heterocyclic derivatives
GB9809350D0 (en) * 1998-05-02 1998-07-01 Zeneca Ltd Novel salt

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EP1031563B1 (de) 2005-12-28
DE69833036D1 (de) 2006-02-02
ES2255733T3 (es) 2006-07-01
AU9280698A (en) 1999-04-23
CN1278793A (zh) 2001-01-03
BR9815377A (pt) 2001-01-16
US20030232808A1 (en) 2003-12-18
ATE314347T1 (de) 2006-01-15
US6525042B1 (en) 2003-02-25
CA2304285A1 (en) 1999-04-08
DE69833036T2 (de) 2006-06-22
DK1031563T3 (da) 2006-05-08
NO20001636L (no) 2000-03-29
JP4256065B2 (ja) 2009-04-22
WO1999016747A1 (en) 1999-04-08
EP1031563A1 (de) 2000-08-30
NO20001636D0 (no) 2000-03-29
KR20010015639A (ko) 2001-02-26
EP1031563A4 (de) 2000-12-06
IL135180A0 (en) 2001-05-20

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