ID24219A - Turunan dibenzotiazotiazepina kristalin dan penggunaannya sebagai zat antipsikotik - Google Patents

Turunan dibenzotiazotiazepina kristalin dan penggunaannya sebagai zat antipsikotik

Info

Publication number: ID24219A
Authority: ID; Indonesia
Prior art keywords: füä1; ethylü; dibenzoäb; hydroxyethoxy; piperazinyl
Prior art date: 1997-08-01

Application number

IDW20000029A

Other languages

English (en)

Inventor

Evan William Snape

Original Assignee

Zeneca Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-08-01

Filing date

1998-07-28

Publication date

2000-07-13

1998-07-28 Application filed by Zeneca Ltd filed Critical Zeneca Ltd

2000-07-13 Publication of ID24219A publication Critical patent/ID24219A/id

Links

239000000126 substance Substances 0.000 title 1
XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 abstract 3
BZLVMXJERCGZMT-UHFFFAOYSA-N Methyl tert-butyl ether Chemical compound COC(C)(C)C BZLVMXJERCGZMT-UHFFFAOYSA-N 0.000 abstract 2
VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 abstract 1
NTIZESTWPVYFNL-UHFFFAOYSA-N Methyl isobutyl ketone Chemical compound CC(C)CC(C)=O NTIZESTWPVYFNL-UHFFFAOYSA-N 0.000 abstract 1
UIHCLUNTQKBZGK-UHFFFAOYSA-N Methyl isobutyl ketone Natural products CCC(C)C(C)=O UIHCLUNTQKBZGK-UHFFFAOYSA-N 0.000 abstract 1
208000028017 Psychotic disease Diseases 0.000 abstract 1
239000003849 aromatic solvent Substances 0.000 abstract 1
239000002178 crystalline material Substances 0.000 abstract 1
GJRQTCIYDGXPES-UHFFFAOYSA-N iso-butyl acetate Natural products CC(C)COC(C)=O GJRQTCIYDGXPES-UHFFFAOYSA-N 0.000 abstract 1
FGKJLKRYENPLQH-UHFFFAOYSA-M isocaproate Chemical compound CC(C)CCC([O-])=O FGKJLKRYENPLQH-UHFFFAOYSA-M 0.000 abstract 1
OQAGVSWESNCJJT-UHFFFAOYSA-N isovaleric acid methyl ester Natural products COC(=O)CC(C)C OQAGVSWESNCJJT-UHFFFAOYSA-N 0.000 abstract 1
229940043265 methyl isobutyl ketone Drugs 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D281/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D281/16—[b, f]-condensed
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Life Sciences & Earth Sciences (AREA)
Neurosurgery (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Psychiatry (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Glass Compositions (AREA)
Iron Core Of Rotating Electric Machines (AREA)
Liquid Crystal Substances (AREA)

IDW20000029A 1997-08-01 1998-07-28 Turunan dibenzotiazotiazepina kristalin dan penggunaannya sebagai zat antipsikotik ID24219A (id)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB9716161.6A GB9716161D0 (en)	1997-08-01	1997-08-01	Process

Publications (1)

Publication Number	Publication Date
ID24219A true ID24219A (id)	2000-07-13

Family

ID=10816746

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IDW20000029A ID24219A (id)	1997-08-01	1998-07-28	Turunan dibenzotiazotiazepina kristalin dan penggunaannya sebagai zat antipsikotik

Country Status (31)

Country	Link
US (2)	US6372734B1 (id)
EP (2)	EP1000043B1 (id)
JP (2)	JP2001512109A (id)
KR (1)	KR20010022241A (id)
CN (1)	CN1125058C (id)
AT (2)	ATE444959T1 (id)
AU (1)	AU739255B2 (id)
BG (1)	BG64796B1 (id)
BR (1)	BR9811061A (id)
CA (1)	CA2295792C (id)
CY (2)	CY2200161T2 (id)
CZ (1)	CZ299225B6 (id)
DE (4)	DE69842104D1 (id)
EE (1)	EE04550B1 (id)
ES (2)	ES2296575T3 (id)
GB (2)	GB9716161D0 (id)
HU (1)	HU228620B1 (id)
ID (1)	ID24219A (id)
IL (1)	IL133618A (id)
MY (1)	MY120999A (id)
NO (1)	NO20000484L (id)
NZ (1)	NZ501914A (id)
PL (1)	PL338384A1 (id)
PT (2)	PT1000043E (id)
RU (1)	RU2224754C2 (id)
SI (2)	SI1589008T1 (id)
SK (1)	SK287145B6 (id)
TR (1)	TR200000848T2 (id)
TW (1)	TW533207B (id)
WO (1)	WO1999006381A1 (id)
ZA (1)	ZA986904B (id)

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AU2003235435A1 (en) *	2002-03-20	2003-10-08	Teva Pharmaceutical Industries Ltd.	Crystalline forms of quetiapine hemifumarate
WO2004076431A1 (en) *	2003-02-22	2004-09-10	Teva Pharmaceutical Industries Ltd.	Synthesis of quetiapine and pharmaceutically acceptable salts thereof
TR200503401T1 (tr) *	2003-03-03	2008-03-21	Hetero Drugs Limited	Kuetiapin (Quetiapine) Fumarat'ın yeni polimorfları
US7053115B2 (en) *	2003-04-07	2006-05-30	Hetero Drugs Limited	Crystalline form of dorzolamide hydrochloride
ES2223294B2 (es)	2003-08-08	2005-10-01	Vita Cientifica, S.L.	Procedimiento de preparacion de un compuesto farmaceuticamente activo.
US20060081361A1 (en) *	2004-09-13	2006-04-20	Gabbey Lawrence W	Oil cooler with integral filter
WO2006035293A1 (en) *	2004-09-27	2006-04-06	Ranbaxy Laboratories Limited	Polymorphic forms of quetiapine hemifumarate
GB0425729D0 (en) *	2004-11-23	2004-12-22	Pliva Res & Dev Ltd	Heterocyclic compounds
WO2006056772A2 (en) *	2004-11-23	2006-06-01	Pliva Hrvatska D.O.O.	Salts of quetiapine
ES2234447B1 (es) *	2005-03-07	2006-03-01	Union Quimico-Farmaceutica S.A.	Procedimiento para la obtencion de un derivado de 11-(4-sustituido-1-piperazinil)dibenzo(b,f)(1,4)tiazepina.
EP1869007A1 (en) *	2005-04-14	2007-12-26	Teva Pharmaceutical Industries Ltd	Process for preparing quetiapine fumarate
US20070072840A1 (en) *	2005-05-30	2007-03-29	Pandya Bhargav	Polymorphic forms of quetiapine
EP1928849A1 (en)	2005-09-30	2008-06-11	Fermion Oy	New crystallization process of quetiapine hemifumarate
WO2007048870A1 (en) *	2005-10-28	2007-05-03	Fermion Oy	Quetiapine hemifumarate purification by crystallization
CN101360502B (zh) *	2005-11-18	2012-03-14	阿斯利康公司	结晶形式
CN101360724A (zh) *	2005-11-18	2009-02-04	阿斯利康公司	盐形式
JP2009516707A (ja) *	2005-11-18	2009-04-23	アストラゼネカ・アクチエボラーグ	固形製剤
US8389510B2 (en) *	2005-11-18	2013-03-05	Astrazeneca Ab	Crystalline forms
WO2007062339A2 (en) *	2005-11-18	2007-05-31	Astrazeneca Ab	Liquid formulations
CZ300451B6 (cs) *	2006-07-03	2009-05-20	Farmak, A. S.	Zpusob prípravy solí 2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanolu (quetiapinu) a jejich cištení
WO2008066620A2 (en) *	2006-10-20	2008-06-05	Concert Pharmaceuticals Inc.	Dibenzothiazepine derivatives
ES2352299T3 (es)	2007-02-14	2011-02-17	Laboratorios Lesvi, S.L.	Composiciones farmacéuticas que contienen fumarato de quetiapina.
EP2144892A2 (en) *	2007-03-29	2010-01-20	Teva Pharmaceutical Industries Ltd.	Improved process for preparing quetiapine fumarate
WO2009004480A2 (en) *	2007-05-07	2009-01-08	Actavis Group Ptc Ehf	Quetiapine salts and their polymorphs
US20090082334A1 (en) *	2007-09-25	2009-03-26	Protia, Llc	Deuterium-enriched quetiapine
WO2009071631A2 (en) *	2007-12-05	2009-06-11	Janssen Pharmaceutica Nv	Dibenzoazepine and dibenzooxazepine trpa1 agonists
DK2262486T3 (da)	2008-08-01	2013-03-25	Krka Tovarna Zdravil D D Novo Mesto	Quetiapin sammensætning
WO2010033270A1 (en) *	2008-09-17	2010-03-25	Auspex Pharmaceuticals, Inc.	Dibenzothiazepine modulators of dopamine, alpha adrenergic, and serotonin receptors
EP2403841A1 (en)	2009-03-04	2012-01-11	Ranbaxy Laboratories Limited	Process for the preparation of quetiapine fumarate
WO2013024072A1 (en)	2011-08-12	2013-02-21	Qiagen Gmbh	Method for isolating nucleic acids

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE787249A (fr)	1971-08-05	1973-02-05	Squibb & Sons Inc	Derives amino d'acides pyrazolopyridine carboxyliques, leurs esters et les sels de ces composes, ainsi que leurs procedes de preparation
GB8607684D0 (en)	1986-03-27	1986-04-30	Ici America Inc	Thiazepine compounds
GB8705574D0 (en) *	1987-03-10	1987-04-15	Ici Plc	Preparation of thiazepine compound

1997
- 1997-08-01 GB GBGB9716161.6A patent/GB9716161D0/en active Pending
1998
- 1998-07-10 GB GBGB9814882.8A patent/GB9814882D0/en active Pending
- 1998-07-28 KR KR1020007000814A patent/KR20010022241A/ko not_active Ceased
- 1998-07-28 DE DE69842104T patent/DE69842104D1/de not_active Expired - Lifetime
- 1998-07-28 TR TR2000/00848T patent/TR200000848T2/xx unknown
- 1998-07-28 SI SI9830929T patent/SI1589008T1/sl unknown
- 1998-07-28 JP JP2000505140A patent/JP2001512109A/ja active Pending
- 1998-07-28 PT PT98936529T patent/PT1000043E/pt unknown
- 1998-07-28 RU RU2000105271/04A patent/RU2224754C2/ru not_active IP Right Cessation
- 1998-07-28 ID IDW20000029A patent/ID24219A/id unknown
- 1998-07-28 AT AT98936529T patent/ATE444959T1/de active
- 1998-07-28 SK SK130-2000A patent/SK287145B6/sk not_active IP Right Cessation
- 1998-07-28 DE DE98936529T patent/DE98936529T1/de active Pending
- 1998-07-28 DE DE05011169T patent/DE05011169T1/de active Pending
- 1998-07-28 PL PL98338384A patent/PL338384A1/xx not_active Application Discontinuation
- 1998-07-28 AU AU85498/98A patent/AU739255B2/en not_active Ceased
- 1998-07-28 CN CN98807572A patent/CN1125058C/zh not_active Expired - Fee Related
- 1998-07-28 AT AT05011169T patent/ATE496037T1/de active
- 1998-07-28 PT PT05011169T patent/PT1589008E/pt unknown
- 1998-07-28 SI SI9830923T patent/SI1000043T1/sl unknown
- 1998-07-28 ES ES98936529T patent/ES2296575T3/es not_active Expired - Lifetime
- 1998-07-28 BR BR9811061-6A patent/BR9811061A/pt not_active Application Discontinuation
- 1998-07-28 TW TW087112313A patent/TW533207B/zh not_active IP Right Cessation
- 1998-07-28 EP EP98936529A patent/EP1000043B1/en not_active Expired - Lifetime
- 1998-07-28 US US09/463,452 patent/US6372734B1/en not_active Expired - Lifetime
- 1998-07-28 NZ NZ501914A patent/NZ501914A/en not_active IP Right Cessation
- 1998-07-28 WO PCT/GB1998/002260 patent/WO1999006381A1/en not_active Ceased
- 1998-07-28 IL IL13361898A patent/IL133618A/en not_active IP Right Cessation
- 1998-07-28 ES ES05011169T patent/ES2296568T3/es not_active Expired - Lifetime
- 1998-07-28 CZ CZ20000341A patent/CZ299225B6/cs not_active IP Right Cessation
- 1998-07-28 HU HU0002663A patent/HU228620B1/hu not_active IP Right Cessation
- 1998-07-28 CA CA002295792A patent/CA2295792C/en not_active Expired - Fee Related
- 1998-07-28 DE DE69841216T patent/DE69841216D1/de not_active Expired - Lifetime
- 1998-07-28 EP EP05011169A patent/EP1589008B1/en not_active Expired - Lifetime
- 1998-07-28 EE EEP200000062A patent/EE04550B1/xx not_active IP Right Cessation
- 1998-07-29 MY MYPI98003471A patent/MY120999A/en unknown
- 1998-07-31 ZA ZA986904A patent/ZA986904B/xx unknown
2000
- 2000-01-31 NO NO20000484A patent/NO20000484L/no unknown
- 2000-02-22 BG BG104176A patent/BG64796B1/bg unknown
2002
- 2002-03-21 US US10/101,948 patent/US20020147186A1/en not_active Abandoned
2008
- 2008-03-04 CY CY20082200004T patent/CY2200161T2/el unknown
- 2008-03-04 CY CY20082200005T patent/CY2200162T2/el unknown
- 2008-12-09 JP JP2008313248A patent/JP2009102345A/ja active Pending

Also Published As

Publication number	Publication date
SI1589008T1 (sl)	2011-04-29
KR20010022241A (ko)	2001-03-15
DE05011169T1 (de)	2008-11-06
EE04550B1 (et)	2005-10-17
RU2224754C2 (ru)	2004-02-27
MY120999A (en)	2005-12-30
CY2200162T2 (el)	2010-07-28
US20020147186A1 (en)	2002-10-10
SK287145B6 (sk)	2010-01-07
HK1081962A1 (en)	2006-05-26
CZ299225B6 (cs)	2008-05-21
US6372734B1 (en)	2002-04-16
NO20000484D0 (no)	2000-01-31
SI1000043T1 (sl)	2010-01-29
ATE444959T1 (de)	2009-10-15
BR9811061A (pt)	2000-09-19
WO1999006381A1 (en)	1999-02-11
EE200000062A (et)	2000-10-16
ES2296575T3 (es)	2010-02-05
PL338384A1 (en)	2000-10-23
BG64796B1 (bg)	2006-04-28
ES2296568T3 (es)	2011-05-06
ATE496037T1 (de)	2011-02-15
PT1000043E (pt)	2009-11-30
CZ2000341A3 (cs)	2000-05-17
EP1589008A1 (en)	2005-10-26
JP2009102345A (ja)	2009-05-14
EP1589008B1 (en)	2011-01-19
NO20000484L (no)	2000-03-16
HK1029992A1 (en)	2001-04-20
CY2200161T2 (el)	2010-07-28
CN1265101A (zh)	2000-08-30
NZ501914A (en)	2001-09-28
PT1589008E (pt)	2011-03-23
DE69842104D1 (de)	2011-03-03
BG104176A (en)	2000-08-31
EP1000043B1 (en)	2009-10-07
HU228620B1 (en)	2013-04-29
ES2296568T1 (es)	2008-05-01
JP2001512109A (ja)	2001-08-21
GB9814882D0 (en)	1998-09-09
CA2295792C (en)	2007-04-17
CA2295792A1 (en)	1999-02-11
ZA986904B (en)	1999-02-01
TR200000848T2 (tr)	2000-08-21
CN1125058C (zh)	2003-10-22
DE98936529T1 (de)	2008-11-20
HUP0002663A2 (hu)	2001-09-28
ES2296575T1 (es)	2008-05-01
AU739255B2 (en)	2001-10-04
AU8549898A (en)	1999-02-22
DE69841216D1 (de)	2009-11-19
IL133618A (en)	2004-02-08
IL133618A0 (en)	2001-04-30
TW533207B (en)	2003-05-21
EP1000043A1 (en)	2000-05-17
GB9716161D0 (en)	1997-10-08
HUP0002663A3 (en)	2001-10-29
SK1302000A3 (en)	2000-06-12

Publication	Publication Date	Title
ID24219A (id)	2000-07-13	Turunan dibenzotiazotiazepina kristalin dan penggunaannya sebagai zat antipsikotik
CO5200832A1 (es)	2002-09-27	Derivados de acidos heterociclicos, o una sal farmaceuticamente aceptable de los mismos, que son agentes antidiabeticos y antiobesidad
DE69431373D1 (de)	2002-10-17	Verfahren zur Herstellung von optisch aktiven 2-Amino-1-Phenylethanol-Derivaten
RU93005051A (ru)	1996-04-20	Способ получения катионных кристаллов гр или производных гр, катионные кристаллы человеческого гр или производных человеческого гр, фармацевтические препараты, использование процесса кристаллизации
BR0115121A (pt)	2003-09-30	Compostos n-((1,2,4)triazoloazinil)tiofenossulfonamida como herbicidas
DE69123025D1 (de)	1996-12-12	Verfahren zur Herstellung von optisch aktiven Gamma-butyrolactonderivaten
DE69813053D1 (de)	2003-05-15	Verfahren zur Herstellung von optisch aktiven Azetidin-2-Carbonsäurederivaten
DE69321304D1 (de)	1998-11-05	Verfahren zur Herstellung von optisch aktivem 4-Methyl-2-oxetanon
DE69410222D1 (de)	1998-06-18	Verfahren zur Herstellung von optisch aktiven Erythro-3-amino-1,2-epoxy-Verbindungen
DE69933526D1 (de)	2006-11-23	Verfahren zur Herstellung von optisch aktiven Oxazolidinonderivate
DE60036758D1 (de)	2007-11-29	Verfahren zur Herstellung von optisch aktiver 3,3,3-Trifluor-2-hydroxy-2-methylpropionsäure und deren Salze
DE69700477D1 (de)	1999-10-14	Verfahren zur Herstellung von optisch aktivem 4-Hydroxy-2-Pyrrolidon
EP0576834A3 (en)	1995-01-11	Process for the production of derivatives of an optically active 1,2-diol.
FI980947L (fi)	1998-04-29	Zeaksantiinin puhdas 3R-3'R-stereoisomeeri silmän keltatäplämuutoksen hoitamiseksi
DE69200795D1 (de)	1995-01-19	Verfahren zur Herstellung von L-Prolinederivaten.
RU97102180A (ru)	1999-02-27	Гомеопатическое лекарственное средство, обладающее спазмолитической активностью "спазминал-arn"
DE59608300D1 (de)	2002-01-10	Verfahren zur Herstellung von optisch aktiven 1-Aryl-alkylaminen
DE69127219D1 (de)	1997-09-18	Verfahren zur Herstellung von optisch aktiven Alkyl-3-aryl-3-hydroxypropionaten
DE59812729D1 (de)	2005-05-19	Verfahren zur Herstellung von 1,3-Dioxanverbindungen
DE68928788D1 (de)	1998-09-24	Verfahren zur Herstellung von optisch aktiven 3,4-Dihydroxybuttersäurederivaten
DE60012240D1 (de)	2004-08-26	Verfahren zur Herstellung von 1,3-Oxazolidinderivaten
ITRM940832A0 (it)	1994-12-23	"cerotto per assorbimento transcutaneo a rilascio controllato di fitoassociazione"
ITRM940831A0 (it)	1994-12-23	"cerotto per assorbimento transcutaneo a rilascio controllato di fitoassociazione"
EP0439129A3 (en)	1991-11-06	Optically active isoxazole derivatives and intermediates for preparation thereof as well as processes for producing the same
ITRM940833A0 (it)	1994-12-23	"cerotto per assorbimento transcutaneo a rilascio controllato di fitoassociazione eventualmente arricchita"