ID26031A - Turunan indol yang memiliki suatu aktivitas antiviral - Google Patents

Turunan indol yang memiliki suatu aktivitas antiviral

Info

Publication number
ID26031A
ID26031A IDW20001898A ID20001898A ID26031A ID 26031 A ID26031 A ID 26031A ID W20001898 A IDW20001898 A ID W20001898A ID 20001898 A ID20001898 A ID 20001898A ID 26031 A ID26031 A ID 26031A
Authority
ID
Indonesia
Prior art keywords
indol
damages
antiviral activity
antiviral
activity
Prior art date
Application number
IDW20001898A
Other languages
English (en)
Indonesian (id)
Inventor
Toshio Fujishita
Tomokazu Yoshinaga
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of ID26031A publication Critical patent/ID26031A/id

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/22Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an aralkyl radical attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IDW20001898A 1998-03-26 1999-03-26 Turunan indol yang memiliki suatu aktivitas antiviral ID26031A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7820398 1998-03-26

Publications (1)

Publication Number Publication Date
ID26031A true ID26031A (id) 2000-11-16

Family

ID=13655476

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20001898A ID26031A (id) 1998-03-26 1999-03-26 Turunan indol yang memiliki suatu aktivitas antiviral

Country Status (17)

Country Link
US (3) US6333323B1 (fr)
EP (1) EP1069111A4 (fr)
JP (1) JP3794469B2 (fr)
KR (1) KR20010041705A (fr)
CN (1) CN1142909C (fr)
AU (1) AU752005B2 (fr)
BR (1) BR9909146A (fr)
CA (1) CA2326166A1 (fr)
HU (1) HUP0103460A3 (fr)
ID (1) ID26031A (fr)
IL (1) IL137974A0 (fr)
NO (1) NO317423B1 (fr)
NZ (1) NZ506435A (fr)
PL (1) PL343249A1 (fr)
RU (1) RU2217421C2 (fr)
WO (1) WO1999050245A1 (fr)
ZA (1) ZA200004047B (fr)

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EP1069111A4 (fr) * 1998-03-26 2001-06-06 Shionogi & Co Derives d'indole exer ant une activite antivirale
WO1999062520A1 (fr) * 1998-06-03 1999-12-09 Merck & Co., Inc. Inhibiteurs de vih integrase
AU757409B2 (en) * 1998-06-03 2003-02-20 Merck & Co., Inc. Hiv integrase inhibitors
PL348596A1 (en) 1998-12-25 2002-06-03 Shionogi & Co Aromatic heterocycle compounds having hiv integrase inhibiting activities
US7294481B1 (en) * 1999-01-05 2007-11-13 Immunex Corporation Method for producing recombinant proteins
AU763231B2 (en) 1999-06-02 2003-07-17 Shionogi & Co., Ltd. Novel processes for the preparation of substituted propenone derivatives
JP2003503386A (ja) * 1999-06-25 2003-01-28 メルク エンド カムパニー インコーポレーテッド 1−(芳香族またはヘテロ芳香族置換)−3−(ヘテロ芳香族置換)−1,3−プロパンジオン類およびそれの使用
EP1219607B1 (fr) * 1999-09-02 2011-04-06 Shionogi & Co., Ltd. Inhibiteur d'integrase contenant des derives heterocycliques aromatiques
KR20030019423A (ko) * 2000-06-13 2003-03-06 시오노기세이야쿠가부시키가이샤 프로페논 유도체를 함유하는 의약 조성물
AU2001262732A1 (en) * 2000-06-14 2001-12-24 Shionogi And Co., Ltd. Inhibitor for enzyme having two divalent metal ions as active centers
JP4395549B2 (ja) * 2000-11-16 2010-01-13 ザ レジェンツ オブ ザ ユニヴァースティ オブ カリフォルニア 薬物及び発酵生成物の発見のための海洋放線菌分類群
US7507767B2 (en) 2001-02-08 2009-03-24 Schering Corporation Cannabinoid receptor ligands
US7067539B2 (en) 2001-02-08 2006-06-27 Schering Corporation Cannabinoid receptor ligands
IL157638A0 (en) 2001-03-01 2004-03-28 Shionogi & Co Nitrogen-containing heteroaryl compounds having hiv integrase inhibitory activity
DK3042894T1 (da) 2001-08-10 2016-11-07 Shionogi & Co Antiviralt middel
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JP2005509032A (ja) 2001-11-14 2005-04-07 シェーリング コーポレイション カンナビノイドレセプターリガンド
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EP1539693B9 (fr) 2002-06-19 2008-10-08 Schering Corporation Agonistes du recepteur cannabinoide
US7176232B2 (en) 2002-06-24 2007-02-13 The Regents Of The University Of California Salinosporamides and methods for use thereof
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DE60316688T2 (de) * 2002-08-02 2008-07-17 Nereus Pharmaceuticals, Inc., San Diego Dehydrophenylahistine und analoge davon sowie ein verfahren zur herstellung von dehydrophenylahistinen und analogen davon
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CN1316968C (zh) * 2005-09-30 2007-05-23 青岛大学 吲哚-2,3-二酮在制备抗病毒或免疫增强剂药物中的应用
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EP1069111A4 (fr) * 1998-03-26 2001-06-06 Shionogi & Co Derives d'indole exer ant une activite antivirale
AU757409B2 (en) 1998-06-03 2003-02-20 Merck & Co., Inc. Hiv integrase inhibitors
CA2329134A1 (fr) 1998-06-03 1999-12-09 David L. Clark Inhibiteurs de vih integrase
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Also Published As

Publication number Publication date
PL343249A1 (en) 2001-07-30
US6506787B2 (en) 2003-01-14
NO20004787L (no) 2000-11-27
HUP0103460A3 (en) 2002-11-28
EP1069111A4 (fr) 2001-06-06
CN1294580A (zh) 2001-05-09
BR9909146A (pt) 2000-12-05
NZ506435A (en) 2002-08-28
HUP0103460A2 (hu) 2002-01-28
EP1069111A1 (fr) 2001-01-17
NO317423B1 (no) 2004-10-25
IL137974A0 (en) 2001-10-31
US6333323B1 (en) 2001-12-25
CA2326166A1 (fr) 1999-10-07
WO1999050245A1 (fr) 1999-10-07
NO20004787D0 (no) 2000-09-25
ZA200004047B (en) 2001-04-25
AU752005B2 (en) 2002-09-05
US6716605B2 (en) 2004-04-06
CN1142909C (zh) 2004-03-24
KR20010041705A (ko) 2001-05-25
US20020019434A1 (en) 2002-02-14
JP3794469B2 (ja) 2006-07-05
US20030181499A1 (en) 2003-09-25
RU2217421C2 (ru) 2003-11-27
AU2958199A (en) 1999-10-18

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