NO20004787L - Indolderivater med antiviral aktivitet - Google Patents
Indolderivater med antiviral aktivitetInfo
- Publication number
- NO20004787L NO20004787L NO20004787A NO20004787A NO20004787L NO 20004787 L NO20004787 L NO 20004787L NO 20004787 A NO20004787 A NO 20004787A NO 20004787 A NO20004787 A NO 20004787A NO 20004787 L NO20004787 L NO 20004787L
- Authority
- NO
- Norway
- Prior art keywords
- antiviral activity
- indole derivatives
- indole
- derivatives
- antiviral
- Prior art date
Links
- 230000000840 anti-viral effect Effects 0.000 title 1
- 229940054051 antipsychotic indole derivative Drugs 0.000 title 1
- 150000002475 indoles Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/22—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an aralkyl radical attached to the ring nitrogen atom
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- AIDS & HIV (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7820398 | 1998-03-26 | ||
| PCT/JP1999/001547 WO1999050245A1 (en) | 1998-03-26 | 1999-03-26 | Indole derivatives with antiviral activity |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20004787D0 NO20004787D0 (no) | 2000-09-25 |
| NO20004787L true NO20004787L (no) | 2000-11-27 |
| NO317423B1 NO317423B1 (no) | 2004-10-25 |
Family
ID=13655476
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20004787A NO317423B1 (no) | 1998-03-26 | 2000-09-25 | Indolderivater, farmasoytisk preparat, middel for a inhibere integrase, antiviralt middel, anti-HIV middel samt anti-HIV medisinsk blanding. |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US6333323B1 (no) |
| EP (1) | EP1069111A4 (no) |
| JP (1) | JP3794469B2 (no) |
| KR (1) | KR20010041705A (no) |
| CN (1) | CN1142909C (no) |
| AU (1) | AU752005B2 (no) |
| BR (1) | BR9909146A (no) |
| CA (1) | CA2326166A1 (no) |
| HU (1) | HUP0103460A3 (no) |
| ID (1) | ID26031A (no) |
| IL (1) | IL137974A0 (no) |
| NO (1) | NO317423B1 (no) |
| NZ (1) | NZ506435A (no) |
| PL (1) | PL343249A1 (no) |
| RU (1) | RU2217421C2 (no) |
| WO (1) | WO1999050245A1 (no) |
| ZA (1) | ZA200004047B (no) |
Families Citing this family (68)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6142163A (en) * | 1996-03-29 | 2000-11-07 | Lam Research Corporation | Method and apparatus for pressure control in vacuum processors |
| CN1142909C (zh) * | 1998-03-26 | 2004-03-24 | 盐野义制药株式会社 | 具有抗病毒活性的吲哚衍生物 |
| WO1999062520A1 (en) * | 1998-06-03 | 1999-12-09 | Merck & Co., Inc. | Hiv integrase inhibitors |
| EP1086091A4 (en) * | 1998-06-03 | 2001-10-10 | Merck & Co Inc | INTEGRASE HIV INHIBITORS |
| ID29027A (id) | 1998-12-25 | 2001-07-26 | Shionogi & Co | Turunan-turunan heteroaromatik yang mempunyai aktivitas penghambatan terhadap integrase hiv |
| US7294481B1 (en) * | 1999-01-05 | 2007-11-13 | Immunex Corporation | Method for producing recombinant proteins |
| TR200103801T2 (tr) | 1999-06-02 | 2002-04-22 | Shonogi & Co., Ltd. | Yeni ikameli propenon türevlerinin hazırlanması için prosesler |
| AU5880600A (en) * | 1999-06-25 | 2001-01-31 | Merck & Co., Inc. | 1-(aromatic- or heteroaromatic-substituted)-3-(heteroaromatic substituted)-1,3-propanediones and uses thereof |
| JP4577751B2 (ja) * | 1999-09-02 | 2010-11-10 | 塩野義製薬株式会社 | 芳香族ヘテロ環誘導体を含有するインテグラーゼ阻害剤 |
| HUP0301713A3 (en) * | 2000-06-13 | 2005-04-28 | Shionogi & Co | Pharmaceutical compositions containing propenone derivatives and their use |
| AU2001262732A1 (en) * | 2000-06-14 | 2001-12-24 | Shionogi And Co., Ltd. | Inhibitor for enzyme having two divalent metal ions as active centers |
| US7144723B2 (en) * | 2000-11-16 | 2006-12-05 | The Regents Of The University Of California | Marine actinomycete taxon for drug and fermentation product discovery |
| US7507767B2 (en) | 2001-02-08 | 2009-03-24 | Schering Corporation | Cannabinoid receptor ligands |
| US7067539B2 (en) | 2001-02-08 | 2006-06-27 | Schering Corporation | Cannabinoid receptor ligands |
| CZ20032332A3 (cs) | 2001-03-01 | 2003-11-12 | Shionogi & Co., Ltd. | Heteroarylové sloučeniny obsahující dusík, které mají inhibiční aktivitu proti HIV integrase |
| JP4338192B2 (ja) | 2001-08-10 | 2009-10-07 | 塩野義製薬株式会社 | 抗ウイルス剤 |
| ITMI20012060A1 (it) * | 2001-10-05 | 2003-04-05 | Recordati Chem Pharm | Nuovi eterocilcli n-acilati |
| HU230248B1 (hu) * | 2001-10-26 | 2015-11-30 | Msd Italia S.R.L. | N-szubsztituált hidroxipirimidinon-karboxamid HIV-integráz inhibitorok |
| CN101684091A (zh) | 2001-11-14 | 2010-03-31 | 先灵公司 | 类大麻苷受体配体 |
| WO2003049695A2 (en) * | 2001-12-07 | 2003-06-19 | The Government Of The United States Of America As Represented By The Secretary, Department Of Healthand Human Services | Compounds to treat hiv infection and aids |
| US20030236277A1 (en) * | 2002-02-14 | 2003-12-25 | Kadow John F. | Indole, azaindole and related heterocyclic pyrrolidine derivatives |
| MXPA04012704A (es) | 2002-06-19 | 2005-03-23 | Schering Corp | Agonistas de los receptores canabinoides. |
| US7176232B2 (en) | 2002-06-24 | 2007-02-13 | The Regents Of The University Of California | Salinosporamides and methods for use thereof |
| DK1529044T5 (da) * | 2002-08-02 | 2008-04-21 | Nereus Pharmaceuticals Inc | Dehydrophenylahistiner og analoger deraf og syntesen af dehydrophenylahistiner og analoger deraf |
| US7935704B2 (en) * | 2003-08-01 | 2011-05-03 | Nereus Pharmaceuticals, Inc. | Dehydrophenylahistins and analogs thereof and the synthesis of dehydrophenylahistins and analogs thereof |
| US7919497B2 (en) | 2002-08-02 | 2011-04-05 | Nereus Pharmaceuticals, Inc. | Analogs of dehydrophenylahistins and their therapeutic use |
| DE60322920D1 (de) | 2002-08-13 | 2008-09-25 | Shionogi & Co | Heterocyclische verbindungen mit hiv-integrase-hemmender wirkung |
| AU2003296908A1 (en) * | 2002-09-27 | 2004-05-04 | Nereus Pharmaceuticals, Inc. | Macrocyclic lactams |
| TW200505902A (en) | 2003-03-20 | 2005-02-16 | Schering Corp | Cannabinoid receptor ligands |
| EP1638552B1 (en) * | 2003-06-20 | 2011-03-02 | Nereus Pharmaceuticals, Inc. | Use of (3.2.0) heterocyclic compounds and analogs thereof for the treatment of cancer |
| NZ544858A (en) * | 2003-06-20 | 2009-07-31 | Univ California | Salinosporamides and methods for use thereof |
| WO2005070922A2 (en) * | 2004-01-23 | 2005-08-04 | Nereus Pharmaceuticals, Inc. | Bis-indole pyrroles useful as antimicrobials agents |
| US7776883B2 (en) | 2004-03-10 | 2010-08-17 | The United States Of America As Represented By The Department Of Health And Human Services | Quinolin-4-ones as inhibitors of retroviral integrase for the treatment of HIV, AIDS and AIDS related complex (ARC) |
| WO2005094816A1 (en) * | 2004-03-11 | 2005-10-13 | Actelion Pharmaceuticals Ltd | Indol-1-yl-acetic acid derivatives |
| BRPI0509824A (pt) | 2004-04-30 | 2007-10-09 | Nereus Pharmaceuticals Inc | compostos heterocìclicos [3.2.0] e métodos de uso dos mesmos |
| US7579371B2 (en) | 2004-04-30 | 2009-08-25 | Nereus Pharmaceuticals, Inc. | Methods of using [3.2.0] heterocyclic compounds and analogs thereof |
| US7534809B2 (en) | 2004-09-17 | 2009-05-19 | Idenix Pharmaceuticals, Inc. | Phospho-indoles as HIV inhibitors |
| US20060100432A1 (en) | 2004-11-09 | 2006-05-11 | Matiskella John D | Crystalline materials of 1-(4-benzoyl-piperazin-1-yl)-2-[4-methoxy-7-(3-methyl-[1,2,4]triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-ethane-1,2-dione |
| PL1830838T3 (pl) | 2004-12-03 | 2013-07-31 | Dana Farber Cancer Inst Inc | Kompozycje i sposoby leczenia chorób neoplastycznych |
| CN1316968C (zh) * | 2005-09-30 | 2007-05-23 | 青岛大学 | 吲哚-2,3-二酮在制备抗病毒或免疫增强剂药物中的应用 |
| US7851476B2 (en) | 2005-12-14 | 2010-12-14 | Bristol-Myers Squibb Company | Crystalline forms of 1-benzoyl-4-[2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-YL)-1-[(phosphonooxy)methyl]-1H-pyrrolo[2,3-C]pyridin-3-YL]-1,2-dioxoethyl]-piperazine |
| CA2644809A1 (en) | 2006-03-02 | 2007-09-07 | Astellas Pharma Inc. | 17 .beta. hsd type 5 inhibitor |
| GB2450268B (en) * | 2006-03-17 | 2011-01-12 | Cipla Ltd | Synthesis of 4-[1-(4-cyano phenyl)-1-(1,2,4-triazol-1-yl)methyl]benzonitrile and 4-[1-(1,2,4-triazol-1-yl)methyl]benzonitrile intermediate |
| MX2008012847A (es) | 2006-04-06 | 2008-10-13 | Nereus Pharmaceuticals Inc | Sintesis total de salinosporamida a y analogos de la misma. |
| US7807671B2 (en) | 2006-04-25 | 2010-10-05 | Bristol-Myers Squibb Company | Diketo-piperazine and piperidine derivatives as antiviral agents |
| EA016267B1 (ru) | 2006-09-29 | 2012-03-30 | Айденикс Фармасьютикалз, Инк. | Энантиомерно чистые фосфоиндолы в качестве ингибиторов hiv |
| US8129527B2 (en) * | 2006-11-03 | 2012-03-06 | Nereus Pharmacuticals, Inc. | Analogs of dehydrophenylahistins and their therapeutic use |
| WO2008095195A2 (en) * | 2007-02-02 | 2008-08-07 | Nereus Pharmaceuticals, Inc. | Lyophilized formulations of salinosporamide a |
| US8394816B2 (en) * | 2007-12-07 | 2013-03-12 | Irene Ghobrial | Methods of using [3.2.0] heterocyclic compounds and analogs thereof in treating Waldenstrom's Macroglobulinemia |
| US20110015158A1 (en) | 2007-12-11 | 2011-01-20 | Viamet Pharmaceuticals, Inc. | Metalloenzyme inhibitors using metal binding moieties in combination with targeting moieties |
| AU2009246467A1 (en) * | 2008-05-12 | 2009-11-19 | Nereus Pharmaceuticals, Inc. | Salinosporamide derivatives as proteasome inhibitors |
| WO2013123658A1 (en) | 2012-02-23 | 2013-08-29 | Empire Technology Development Llc | Azobenzene compounds with cholesterol group and their sunscreen compositions |
| CN103420894A (zh) * | 2012-05-22 | 2013-12-04 | 中国科学院上海药物研究所 | 丁-2-烯-1,4-二酮类化合物及其制备方法和用途 |
| SG10201901242PA (en) | 2014-09-14 | 2019-03-28 | Avanir Pharmaceuticals Inc | Pharmaceutical compositions comprising a dextromethorphan compound and quinidine for the treatment of agitation in dementia |
| EP3265091A4 (en) | 2015-03-06 | 2018-08-01 | Beyondspring Pharmaceuticals Inc. | Method of treating a brain tumor |
| HK1249052A1 (zh) | 2015-03-06 | 2018-10-26 | BeyondSpring Pharmaceuticals Inc. | 治疗与ras突变相关的癌症的方法 |
| EP3277665B1 (en) * | 2015-03-31 | 2020-03-04 | The Royal Institution for the Advancement of Learning / McGill University | Indole analogs as 5-oxo-ete receptor antagonists and method of use thereof |
| MX376122B (es) | 2015-07-13 | 2025-03-07 | Beyondspring Pharmaceuticals Inc | Composiciones de plinabulina. |
| SG11201806583XA (en) | 2016-02-08 | 2018-09-27 | Beyondspring Pharmaceuticals Inc | Compositions containing tucaresol or its analogs |
| BR112018074990A2 (pt) | 2016-06-06 | 2019-03-12 | Beyondspring Pharmaceuticals, Inc. | composição, usos e método para reduzir neutropenia |
| US11633393B2 (en) | 2017-01-06 | 2023-04-25 | Beyondspring Pharmaceuticals, Inc. | Tubulin binding compounds and therapeutic use thereof |
| EP3576733A4 (en) | 2017-02-01 | 2020-11-25 | Beyondspring Pharmaceuticals, Inc. | NEUTROPENIA REDUCTION METHOD |
| CN106995400B (zh) * | 2017-04-10 | 2019-08-06 | 湘潭大学 | 一种化合物及其盐及其合成方法 |
| CN107226810B (zh) * | 2017-06-16 | 2020-04-28 | 郑州大学 | 吲哚衍生物及其制备方法和其抗流感病毒作用 |
| KR20200112881A (ko) | 2018-01-24 | 2020-10-05 | 비욘드스프링 파마수티컬스, 인코포레이티드. | 플리나불린의 투여를 통해 혈소판감소증을 감소시키는 조성물 및 방법 |
| CN109810044B (zh) * | 2019-02-27 | 2022-05-03 | 贵州医科大学 | 一种具有hiv-1整合酶抑制活性的化合物及其制备和应用 |
| EP4319751A4 (en) | 2021-04-09 | 2025-02-26 | Beyondspring Pharmaceuticals, Inc. | THERAPEUTIC COMPOSITIONS AND METHODS FOR THE TREATING OF TUMORS |
| US20250154145A1 (en) * | 2021-12-20 | 2025-05-15 | Fairhaven Pharmaceuticals Ins. | Oxer1 antagonists and uses thereof |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4377698A (en) * | 1976-01-22 | 1983-03-22 | Sterling Drug Inc. | 2,4 Bis(2-indolyl-3)-4-oxobutanoic acids |
| JPH07110852B2 (ja) * | 1989-12-28 | 1995-11-29 | ジ・アップジョン・カンパニー | 二芳香族置換抗aids化合物 |
| WO1993005020A1 (en) * | 1991-09-06 | 1993-03-18 | Merck & Co., Inc. | Indoles as inhibitors of hiv reverse transcriptase |
| US5527819A (en) * | 1991-09-06 | 1996-06-18 | Merck & Co., Inc. | Inhibitors of HIV reverse transcriptase |
| US5124327A (en) * | 1991-09-06 | 1992-06-23 | Merck & Co., Inc. | HIV reverse transcriptase |
| US5475109A (en) * | 1994-10-17 | 1995-12-12 | Merck & Co., Inc. | Dioxobutanoic acid derivatives as inhibitors of influenza endonuclease |
| KR100430059B1 (ko) * | 1995-04-10 | 2004-09-24 | 후지사와 야꾸힝 고교 가부시키가이샤 | cGMP-PDE억제제로서의인돌유도체 |
| US5858738A (en) * | 1996-11-07 | 1999-01-12 | Merck & Co., Inc. | Ermophilane sesquiterpenoids as HIV intergrase inhibitors |
| CN1142909C (zh) * | 1998-03-26 | 2004-03-24 | 盐野义制药株式会社 | 具有抗病毒活性的吲哚衍生物 |
| WO1999062520A1 (en) | 1998-06-03 | 1999-12-09 | Merck & Co., Inc. | Hiv integrase inhibitors |
| CA2329134A1 (en) | 1998-06-03 | 1999-12-09 | David L. Clark | Hiv integrase inhibitors |
| EP1086091A4 (en) | 1998-06-03 | 2001-10-10 | Merck & Co Inc | INTEGRASE HIV INHIBITORS |
| AU5880600A (en) | 1999-06-25 | 2001-01-31 | Merck & Co., Inc. | 1-(aromatic- or heteroaromatic-substituted)-3-(heteroaromatic substituted)-1,3-propanediones and uses thereof |
-
1999
- 1999-03-26 CN CNB998044180A patent/CN1142909C/zh not_active Expired - Fee Related
- 1999-03-26 JP JP2000541150A patent/JP3794469B2/ja not_active Expired - Fee Related
- 1999-03-26 ID IDW20001898A patent/ID26031A/id unknown
- 1999-03-26 BR BR9909146-1A patent/BR9909146A/pt not_active IP Right Cessation
- 1999-03-26 US US09/622,543 patent/US6333323B1/en not_active Expired - Fee Related
- 1999-03-26 AU AU29581/99A patent/AU752005B2/en not_active Ceased
- 1999-03-26 IL IL13797499A patent/IL137974A0/xx unknown
- 1999-03-26 HU HU0103460A patent/HUP0103460A3/hu unknown
- 1999-03-26 CA CA002326166A patent/CA2326166A1/en not_active Abandoned
- 1999-03-26 EP EP99910719A patent/EP1069111A4/en not_active Withdrawn
- 1999-03-26 KR KR1020007009926A patent/KR20010041705A/ko not_active Ceased
- 1999-03-26 RU RU2000126474/04A patent/RU2217421C2/ru not_active IP Right Cessation
- 1999-03-26 WO PCT/JP1999/001547 patent/WO1999050245A1/ja not_active Ceased
- 1999-03-26 NZ NZ506435A patent/NZ506435A/xx unknown
- 1999-03-26 PL PL99343249A patent/PL343249A1/xx unknown
-
2000
- 2000-08-08 ZA ZA200004047A patent/ZA200004047B/xx unknown
- 2000-09-25 NO NO20004787A patent/NO317423B1/no not_active IP Right Cessation
-
2001
- 2001-08-15 US US09/929,486 patent/US6506787B2/en not_active Expired - Fee Related
-
2002
- 2002-09-30 US US10/259,903 patent/US6716605B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1069111A4 (en) | 2001-06-06 |
| US6716605B2 (en) | 2004-04-06 |
| HUP0103460A3 (en) | 2002-11-28 |
| US20020019434A1 (en) | 2002-02-14 |
| PL343249A1 (en) | 2001-07-30 |
| BR9909146A (pt) | 2000-12-05 |
| US6333323B1 (en) | 2001-12-25 |
| US6506787B2 (en) | 2003-01-14 |
| HUP0103460A2 (hu) | 2002-01-28 |
| CN1294580A (zh) | 2001-05-09 |
| ID26031A (id) | 2000-11-16 |
| WO1999050245A1 (en) | 1999-10-07 |
| RU2217421C2 (ru) | 2003-11-27 |
| IL137974A0 (en) | 2001-10-31 |
| KR20010041705A (ko) | 2001-05-25 |
| ZA200004047B (en) | 2001-04-25 |
| US20030181499A1 (en) | 2003-09-25 |
| AU2958199A (en) | 1999-10-18 |
| NZ506435A (en) | 2002-08-28 |
| NO20004787D0 (no) | 2000-09-25 |
| JP3794469B2 (ja) | 2006-07-05 |
| CN1142909C (zh) | 2004-03-24 |
| AU752005B2 (en) | 2002-09-05 |
| EP1069111A1 (en) | 2001-01-17 |
| NO317423B1 (no) | 2004-10-25 |
| CA2326166A1 (en) | 1999-10-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO20004787L (no) | Indolderivater med antiviral aktivitet | |
| IS5635A (is) | Indólýl-3-glýoxýlsýru afleiður með virkni gegn æxlum | |
| NO20010743D0 (no) | Antivirale indoloksoacetyl-piperazin-derivater | |
| NO20011183D0 (no) | 4,4-biarylpiperidinderivater med opoid reseptoraktivitet | |
| BR9701877A (pt) | Derivados de aza-hexano heterocíclicos antiviralmente ativos | |
| ATE321065T1 (de) | Purin-derivate | |
| DK1220863T3 (da) | Purinderivater | |
| NO20016109L (no) | Purinderivater | |
| ATE231874T1 (de) | Antivirale purin-derivate | |
| PT1044977E (pt) | Derivados de camptotecina com actividade antitumoral | |
| ATE277941T1 (de) | Adenosinderivate | |
| DK1240157T3 (da) | Substituerede N-benzyl-indol-3-yl-glyoxylsyrederivater med antitumorvirkning | |
| ATE231508T1 (de) | Azyklische nukleosidderivate | |
| NO20020565D0 (no) | Interleukin-5-hemmende 6-azauracilderivater | |
| NO992103L (no) | Dihydropyroner med forbedret antiviral aktivitet | |
| NO983089D0 (no) | 2-amino-5,6-diklorbenzimidazol-derivater med antiviral aktivitet |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ERR | Erratum |
Free format text: INDOLDERIVATER, FARMASOYTISK PREPARAT, MIDDEL FOR A INHIBERE INTEGRASE, ANTIVIRALT MIDDEL, ANTI-HIVMIDDEL SAMT ANTI-HIV MEDISINSK BLANDING. |
|
| MM1K | Lapsed by not paying the annual fees |