IE890950L - Novel polypeptides having growth factor activity and nucleic acid sequences enclding the polypeptides - Google Patents

Novel polypeptides having growth factor activity and nucleic acid sequences enclding the polypeptides

Info

Publication number
IE890950L
IE890950L IE890950A IE95089A IE890950L IE 890950 L IE890950 L IE 890950L IE 890950 A IE890950 A IE 890950A IE 95089 A IE95089 A IE 95089A IE 890950 L IE890950 L IE 890950L
Authority
IE
Ireland
Prior art keywords
polypeptides
growth factor
enclding
nucleic acid
acid sequences
Prior art date
Application number
IE890950A
Other languages
English (en)
Original Assignee
Patrick O Mahony
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Patrick O Mahony filed Critical Patrick O Mahony
Publication of IE890950L publication Critical patent/IE890950L/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/485—Epidermal growth factor [EGF], i.e. urogastrone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/495—Transforming growth factor [TGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
    • C12N2710/24122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Plant Pathology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
IE890950A 1988-03-24 1989-03-23 Novel polypeptides having growth factor activity and nucleic acid sequences enclding the polypeptides IE890950L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17265388A 1988-03-24 1988-03-24

Publications (1)

Publication Number Publication Date
IE890950L true IE890950L (en) 1989-09-24

Family

ID=22628611

Family Applications (1)

Application Number Title Priority Date Filing Date
IE890950A IE890950L (en) 1988-03-24 1989-03-23 Novel polypeptides having growth factor activity and nucleic acid sequences enclding the polypeptides

Country Status (22)

Country Link
JP (1) JPH0279981A (fr)
KR (1) KR890014743A (fr)
AU (2) AU3169589A (fr)
BE (1) BE1004202A5 (fr)
CH (1) CH681081A5 (fr)
DE (1) DE3910084A1 (fr)
DK (1) DK146789A (fr)
ES (1) ES2013408A6 (fr)
FI (1) FI891308A7 (fr)
FR (1) FR2632321A1 (fr)
GB (1) GB2219799B (fr)
GR (1) GR1000876B (fr)
HU (1) HUT50501A (fr)
IE (1) IE890950L (fr)
IL (1) IL89673A0 (fr)
IT (1) IT1234961B (fr)
LU (1) LU87489A1 (fr)
NL (1) NL8900724A (fr)
NO (1) NO891273D0 (fr)
NZ (1) NZ228427A (fr)
PT (1) PT90118B (fr)
SE (1) SE8901031L (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0293785A3 (fr) * 1987-05-29 1990-05-02 Oncogen Limited Partnership Clonage et expression du facteur de croissance transformant simien SS-1
EP0444961A1 (fr) * 1990-03-02 1991-09-04 Bristol-Myers Squibb Company Her3: Un nouveau homologue d'EGF-récepteur
EP0739984A1 (fr) * 1995-04-26 1996-10-30 San Tumorforschungs-Gmbh Polypeptides bivalents contenants aux moins deux domaines
US6852506B1 (en) 1996-04-10 2005-02-08 Human Genome Sciences, Inc. Extracellular/epidermal growth factor-like protein
AU5549296A (en) * 1996-04-10 1997-10-29 Human Genome Sciences, Inc. Extracellular/epidermal growth factor-like protein

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1983004030A1 (fr) * 1982-05-06 1983-11-24 Applied Molecular Genetics, Inc. Fabrication et expression de genes pour l'urogastrone et leurs analogues polypeptides
JPS6028994A (ja) * 1983-07-08 1985-02-14 Wakunaga Seiyaku Kk 〔２１―ロイシン〕ヒトウロガストロン
WO1985002198A1 (fr) * 1983-11-01 1985-05-23 Amgen Expression microbienne du facteur de croissance transformant du type i, de ses analogues polypeptidiques et des polypeptides hybrides de l'egf et du tgf
JP2554459B2 (ja) * 1984-07-02 1996-11-13 アース製薬 株式会社 β−ウロガストロン遺伝子、対応プラスミド組換体及び対応形質転換体
EP0199769A4 (fr) * 1984-10-30 1989-11-29 Oncogen Nouveaux polypeptides ayant une activite de facteur de croissance et sequences d'acides nucleiques de codage de ces polypeptides.
GB8507666D0 (en) * 1985-03-25 1985-05-01 Wellcome Found Epidermal growth factor production
US4743679A (en) * 1986-02-24 1988-05-10 Creative Biomolecules, Inc. Process for producing human epidermal growth factor and analogs thereof
GB2210618B (en) * 1987-10-08 1991-10-16 British Bio Technology Synthetic egf gene
ES2081801T3 (es) * 1987-10-30 1996-03-16 Bristol Myers Squibb Co Plasmidos de expresion.
WO1989003886A1 (fr) * 1987-10-30 1989-05-05 Oncogen, A Limited Partnership Systemes d'expression destines a la preparation de polypeptides dans des cellules procaryotiques

Also Published As

Publication number Publication date
AU3169589A (en) 1989-09-28
SE8901031D0 (sv) 1989-03-22
BE1004202A5 (fr) 1992-10-13
SE8901031L (sv) 1989-09-25
AU2990492A (en) 1993-03-04
LU87489A1 (fr) 1989-10-26
IT8919917A0 (it) 1989-03-24
KR890014743A (ko) 1989-10-25
PT90118A (pt) 1989-11-10
JPH0279981A (ja) 1990-03-20
NO891273D0 (no) 1989-03-22
NZ228427A (en) 1993-03-26
GB2219799A (en) 1989-12-20
CH681081A5 (fr) 1993-01-15
ES2013408A6 (es) 1990-05-01
GR890100185A (en) 1990-01-19
HUT50501A (en) 1990-02-28
DE3910084A1 (de) 1989-11-16
GB8906758D0 (en) 1989-05-10
FR2632321A1 (fr) 1989-12-08
NL8900724A (nl) 1989-10-16
DK146789A (da) 1989-09-25
FI891308A0 (fi) 1989-03-20
IL89673A0 (en) 1989-09-28
GB2219799B (en) 1992-10-14
FI891308L (fi) 1989-09-25
DK146789D0 (da) 1989-03-22
GR1000876B (el) 1993-03-16
PT90118B (pt) 1994-07-29
FI891308A7 (fi) 1989-09-25
IT1234961B (it) 1992-06-09

Similar Documents

Publication Publication Date Title
CA2105998A1 (fr) Recepteurs humains de pf4a et leur utilisation
ES2170962T3 (es) Catalizador acido solido y procedimiento para su obtencion.
DE10075006I1 (de) Verwendung von (s)(+)-2-aethoxy-4- N- 1-(2piperidino-phenyl)-3-methyl-1-butyl aminocarbonylmethyl-Benzoesaeure zur Herstellung eines Langzeitantidiabetikums
EP0846762A3 (fr) Nouveau recepteur V31 du genre sept-transmembrane
CA2448281A1 (fr) Resolution optique de (1-benzyl-4-methylpiperidine-3-yle) methylamine et son utilisation pour la preparation de derives de pyrrolo 2,3-pyrimidine utilises comme inhibiteurs de proteines kinase
AU7575487A (en) Method for the preparation of proteins with factor VIII activity by microbial host cells; expression, vectors, host cells, antibodies
DE69034022D1 (de) Verfahren zur Herstellung von Fusionsproteinen
DE69710067D1 (de) Zusammensetzung aus ceriumoxid und zirkoniumoxid, verfahren zur herstellung und verwendung in katalyse
DE59002375D1 (de) Verwendung von (meth) acryloylgruppen aufweisenden polyurethanen als bindemittel fuer pulverlacke.
IE901712L (en) Fungicidal agents, and substituted amino acid amide¹derivatives and their preparation
DE69425650D1 (de) Herstellung eines abriebbeständigen katalysatorbindemittels unter verwendung von entlaminiertem ton
IE890950L (en) Novel polypeptides having growth factor activity and nucleic acid sequences enclding the polypeptides
CA2064814A1 (fr) Recepteur de facteur de stimulation de colonies de macrophages-granulocytes
IE861571L (en) Sulfonic acid esters.
DE69925992D1 (de) VERFAHREN ZUR HERSTELLUNG VON 5-HYDROXYBENZO[b]THIOPHEN-3-CARBONSÄURE
ATE88751T1 (de) Monoklonaler antikoerper spezifisch gegen neutrophilen.
DE69810531D1 (de) Verfahren zur Herstellung von Naphtalin-2,6-dicarbonsäure
DE69802811D1 (de) Verfahren zur herstellung von polyborazylen mesophase, polyborazylen mesophase, ihre verwendung als bn-vorläufer
EP0231442A3 (fr) Liant réactif
ATE37534T1 (de) Arylethanolhydroxylamine, verfahren zu ihrer herstellung und ihre verwendung zur leistungsfoerderung.
ES8802185A1 (es) Un metodo para preparar un anticuerpo util para la deteccion de un factor de crecimiento epidermico
DE3671603D1 (de) Verfahren zur zucht von babesia canis, verwendung zur herstellung von antigenen und impfstoffen und antigene und impfstoffe gegen piroplasmose.
ATE102921T1 (de) (alfa-t-butyl aminomethyl-3,4-dichlorobenzyl) thioacetamid, verfahren zu ihrer herstellung und ihre verwendung.
JPS6421904A (en) Case for baking ferrite
Watson et al. John B. Watson's Behaviorism: A Retrospective Review