IE902655A1 - 2-amino-7-carbamoyl-1,2,3,4-tetrahydronaphthalenes,¹processes for their preparation and their use as¹medicaments - Google Patents

2-amino-7-carbamoyl-1,2,3,4-tetrahydronaphthalenes,¹processes for their preparation and their use as¹medicaments

Info

Publication number
IE902655A1
IE902655A1 IE265590A IE265590A IE902655A1 IE 902655 A1 IE902655 A1 IE 902655A1 IE 265590 A IE265590 A IE 265590A IE 265590 A IE265590 A IE 265590A IE 902655 A1 IE902655 A1 IE 902655A1
Authority
IE
Ireland
Prior art keywords
denotes
formula
alkyl
hydrogen
acid
Prior art date
Application number
IE265590A
Other languages
English (en)
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of IE902655A1 publication Critical patent/IE902655A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/48—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring being part of a condensed ring system of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IE265590A 1989-07-22 1990-07-20 2-amino-7-carbamoyl-1,2,3,4-tetrahydronaphthalenes,¹processes for their preparation and their use as¹medicaments IE902655A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3924365A DE3924365A1 (de) 1989-07-22 1989-07-22 2-amino-7-carbamoyl-1,2,3,4- tetrahydronaphthaline, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
IE902655A1 true IE902655A1 (en) 1991-02-27

Family

ID=6385664

Family Applications (1)

Application Number Title Priority Date Filing Date
IE265590A IE902655A1 (en) 1989-07-22 1990-07-20 2-amino-7-carbamoyl-1,2,3,4-tetrahydronaphthalenes,¹processes for their preparation and their use as¹medicaments

Country Status (13)

Country Link
EP (1) EP0435988A1 (de)
JP (1) JPH04500815A (de)
KR (1) KR920701133A (de)
AU (1) AU630725B2 (de)
CA (1) CA2033323A1 (de)
DD (1) DD297401A5 (de)
DE (1) DE3924365A1 (de)
IE (1) IE902655A1 (de)
IL (1) IL95142A0 (de)
NZ (1) NZ234590A (de)
PT (1) PT94780A (de)
WO (1) WO1991001297A1 (de)
ZA (1) ZA905715B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69032725T2 (de) * 1989-05-31 1999-04-08 Pharmacia & Upjohn Co., Kalamazoo, Mich. ZNS-wirksame 8-Heterocyclyl-2-aminotetralin Derivate
EP0499755A1 (de) * 1991-02-18 1992-08-26 MIDY S.p.A. Phenylethanolaminotetraline, Verfahren zu deren Herstellung, Zwischenprodukte davon und diese enthaltende pharmazeutische Zusammensetzungen
DK148292D0 (da) * 1992-12-09 1992-12-09 Lundbeck & Co As H Forbindelser
NZ569608A (en) * 2006-01-06 2011-09-30 Sepracor Inc Tetralone-based monoamine reuptake inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4448990A (en) * 1982-11-16 1984-05-15 Eli Lilly And Company Hydroxyaminotetralincarboxamides
DE3719924A1 (de) * 1986-12-22 1988-06-30 Bayer Ag 8-substituierte 2-aminotetraline
DE69032725T2 (de) * 1989-05-31 1999-04-08 Pharmacia & Upjohn Co., Kalamazoo, Mich. ZNS-wirksame 8-Heterocyclyl-2-aminotetralin Derivate

Also Published As

Publication number Publication date
PT94780A (pt) 1991-03-20
DD297401A5 (de) 1992-01-09
IL95142A0 (en) 1991-06-10
JPH04500815A (ja) 1992-02-13
AU630725B2 (en) 1992-11-05
EP0435988A1 (de) 1991-07-10
CA2033323A1 (en) 1991-01-23
AU5958690A (en) 1991-02-22
NZ234590A (en) 1992-07-28
WO1991001297A1 (de) 1991-02-07
DE3924365A1 (de) 1991-01-24
ZA905715B (en) 1992-03-25
KR920701133A (ko) 1992-08-11

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