IE920392A1 - Lipoxygenase-inhibiting hydroxamic acid and n-hydroxyurea¹derivatives - Google Patents

Lipoxygenase-inhibiting hydroxamic acid and n-hydroxyurea¹derivatives

Info

Publication number
IE920392A1
IE920392A1 IE039292A IE920392A IE920392A1 IE 920392 A1 IE920392 A1 IE 920392A1 IE 039292 A IE039292 A IE 039292A IE 920392 A IE920392 A IE 920392A IE 920392 A1 IE920392 A1 IE 920392A1
Authority
IE
Ireland
Prior art keywords
alkyl
hydroxy
aryl
compound
oxygen
Prior art date
Application number
IE039292A
Other languages
English (en)
Inventor
Rodney W Stevens
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IE920392A1 publication Critical patent/IE920392A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/14—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/22—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Lubricants (AREA)
IE039292A 1991-02-07 1992-02-06 Lipoxygenase-inhibiting hydroxamic acid and n-hydroxyurea¹derivatives IE920392A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3016325A JPH0730061B2 (ja) 1991-02-07 1991-02-07 ヒドロキサム酸誘導体および組成物

Publications (1)

Publication Number Publication Date
IE920392A1 true IE920392A1 (en) 1992-08-12

Family

ID=11913313

Family Applications (1)

Application Number Title Priority Date Filing Date
IE039292A IE920392A1 (en) 1991-02-07 1992-02-06 Lipoxygenase-inhibiting hydroxamic acid and n-hydroxyurea¹derivatives

Country Status (21)

Country Link
EP (1) EP0570401B1 (ja)
JP (1) JPH0730061B2 (ja)
KR (1) KR930703279A (ja)
AT (1) ATE113942T1 (ja)
AU (1) AU648872B2 (ja)
CA (1) CA2101539A1 (ja)
DE (1) DE69200665T2 (ja)
DK (1) DK0570401T3 (ja)
ES (1) ES2063578T3 (ja)
FI (1) FI933492L (ja)
HU (1) HUT65539A (ja)
IE (1) IE920392A1 (ja)
IL (1) IL100846A0 (ja)
MX (1) MX9200519A (ja)
MY (1) MY134478A (ja)
NO (1) NO932815L (ja)
NZ (1) NZ241530A (ja)
PT (1) PT100093A (ja)
TW (1) TW222627B (ja)
WO (1) WO1992013848A1 (ja)
ZA (1) ZA92862B (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639782A (en) * 1992-03-04 1997-06-17 Center For Innovative Technology Neolignan derivatives as platelet activating factor receptor antagonists and 5-lipoxygenase inhibitors
US5463083A (en) 1992-07-13 1995-10-31 Cytomed, Inc. Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
JPH08502243A (ja) 1992-07-13 1996-03-12 サイトメッド，インコーポレイテッド 炎症性および免疫性疾患の治療のための２，５‐ジアリールテトラヒドロ‐チオフェン、‐フランおよび類似体
US5434151A (en) * 1992-08-24 1995-07-18 Cytomed, Inc. Compounds and methods for the treatment of disorders mediated by platelet activating factor or products of 5-lipoxygenase
US5792776A (en) * 1994-06-27 1998-08-11 Cytomed, Inc., Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
US5750565A (en) 1995-05-25 1998-05-12 Cytomed, Inc. Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
US5703093A (en) * 1995-05-31 1997-12-30 Cytomed, Inc. Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
US6201016B1 (en) * 1994-06-27 2001-03-13 Cytomed Incorporated Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
CN1151125C (zh) * 1994-06-27 2004-05-26 千年药品公司 治疗心血管疾病,炎症和免疫疾病的化合物和方法
MX9701042A (es) * 1996-02-07 1998-05-31 Pfizer Compuestos del acido hidroxamico.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1044308A (en) * 1964-04-28 1966-09-28 Langbein Pfanhauser Werke Ag Electrodeposition of bright copper
US3393209A (en) * 1965-10-04 1968-07-16 Dow Chemical Co Furfuryl and tetrahydrofurfuryl phenyl ureas
JPS5742632B2 (ja) * 1972-12-25 1982-09-09
ES2059408T3 (es) * 1987-02-10 1994-11-16 Abbott Lab Un proceso para la preparacion de un compuesto.
GB2201008B (en) * 1987-02-12 1991-10-23 Stc Plc Optical fibre cables

Also Published As

Publication number Publication date
NO932815L (no) 1993-08-09
ATE113942T1 (de) 1994-11-15
AU1173692A (en) 1992-09-07
ZA92862B (en) 1993-08-06
FI933492A0 (fi) 1993-08-06
JPH0730061B2 (ja) 1995-04-05
HU9302283D0 (en) 1993-10-28
ES2063578T3 (es) 1995-01-01
KR930703279A (ko) 1993-11-29
DE69200665D1 (de) 1994-12-15
JPH04257571A (ja) 1992-09-11
EP0570401B1 (en) 1994-11-09
NO932815D0 (no) 1993-08-06
IL100846A0 (en) 1992-11-15
AU648872B2 (en) 1994-05-05
PT100093A (pt) 1993-03-31
TW222627B (ja) 1994-04-21
NZ241530A (en) 1994-06-27
FI933492A7 (fi) 1993-08-06
MX9200519A (es) 1992-08-31
HUT65539A (en) 1994-06-28
CA2101539A1 (en) 1992-08-08
DE69200665T2 (de) 1995-04-06
EP0570401A1 (en) 1993-11-24
DK0570401T3 (da) 1994-12-05
MY134478A (en) 2007-12-31
FI933492L (fi) 1993-08-06
WO1992013848A1 (en) 1992-08-20

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Legal Events

Date Code Title Description
FJ9A Application deemed to be withdrawn section 31(3)