IL102687A - Conjugates of poorly immunogenic antigens and synthetic pepide carriers and vaccines comprising them - Google Patents

Conjugates of poorly immunogenic antigens and synthetic pepide carriers and vaccines comprising them

Info

Publication number
IL102687A
IL102687A IL102687A IL10268792A IL102687A IL 102687 A IL102687 A IL 102687A IL 102687 A IL102687 A IL 102687A IL 10268792 A IL10268792 A IL 10268792A IL 102687 A IL102687 A IL 102687A
Authority
IL
Israel
Prior art keywords
poorly immunogenic
synthetic
pepide
vaccines
conjugates
Prior art date
Application number
IL102687A
Other languages
English (en)
Other versions
IL102687A0 (en
Inventor
R Cohen Irun
Fridkin Matityahu
Konen-Waisman Stephanie
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Priority to IL102687A priority Critical patent/IL102687A/xx
Publication of IL102687A0 publication Critical patent/IL102687A0/xx
Priority to AT93918458T priority patent/ATE188612T1/de
Priority to JP50541094A priority patent/JP4087898B2/ja
Priority to US08/379,613 priority patent/US5736146A/en
Priority to PCT/US1993/007096 priority patent/WO1994003208A1/en
Priority to CZ95229A priority patent/CZ22995A3/cs
Priority to PL93307297A priority patent/PL174082B1/pl
Priority to HU9500270A priority patent/HU218425B/hu
Priority to CA002141454A priority patent/CA2141454C/en
Priority to KR1019950700401A priority patent/KR100290632B1/ko
Priority to DE69327587T priority patent/DE69327587T2/de
Priority to AU47900/93A priority patent/AU683421B2/en
Priority to FI950405A priority patent/FI950405L/fi
Priority to SK112-95A priority patent/SK11295A3/sk
Priority to EP93918458A priority patent/EP0658120B1/en
Priority to NZ255143A priority patent/NZ255143A/en
Priority to BR9306820A priority patent/BR9306820A/pt
Priority to RU95105991/14A priority patent/RU95105991A/ru
Priority to NO950328A priority patent/NO950328L/no
Publication of IL102687A publication Critical patent/IL102687A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0275—Salmonella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6043—Heat shock proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
    • A61K2039/627—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
IL102687A 1992-07-30 1992-07-30 Conjugates of poorly immunogenic antigens and synthetic pepide carriers and vaccines comprising them IL102687A (en)

Priority Applications (19)

Application Number Priority Date Filing Date Title
IL102687A IL102687A (en) 1992-07-30 1992-07-30 Conjugates of poorly immunogenic antigens and synthetic pepide carriers and vaccines comprising them
RU95105991/14A RU95105991A (ru) 1992-07-30 1993-07-28 Конъюгат, вакцина, способы усиления иммуногенности, способы иммунизации
CA002141454A CA2141454C (en) 1992-07-30 1993-07-28 Conjugates of poorly immunogenic antigens and synthetic peptide carriers and vaccines comprising them
DE69327587T DE69327587T2 (de) 1992-07-30 1993-07-28 Konjugate von schwach immunogenen antigenen und synthetischen peptidträgern und impfstoffe diese enthaltend
US08/379,613 US5736146A (en) 1992-07-30 1993-07-28 Conjugates of poorly immunogenic antigens and synthetic peptide carriers and vaccines comprising them
PCT/US1993/007096 WO1994003208A1 (en) 1992-07-30 1993-07-28 Conjugates of poorly immunogenic antigens and synthetic peptide carriers and vaccines comprising them
CZ95229A CZ22995A3 (en) 1992-07-30 1993-07-28 Conjugate of little immunogenic antigen and synthetic peptide carrier, vaccine containing thereof and method of increasing immunogenity
PL93307297A PL174082B1 (pl) 1992-07-30 1993-07-28 Koniugat kapsularnego polisacharydu (Vi) i związanego z nim nośnika oraz sposób wytwarzania koniugatu
HU9500270A HU218425B (hu) 1992-07-30 1993-07-28 Antigének és szintetikus peptid hordozók konjugátumai és ezeket tartalmazó vakcinák
AT93918458T ATE188612T1 (de) 1992-07-30 1993-07-28 Konjugate von schwach immunogenen antigenen und synthetischen peptidträgern und impfstoffe diese enthaltend
KR1019950700401A KR100290632B1 (ko) 1992-07-30 1993-07-28 면역성이약한항원공액체와이를포함하는합성펩티드담체와백신
JP50541094A JP4087898B2 (ja) 1992-07-30 1993-07-28 免疫原性に乏しい抗原と合成ペプチド担体との結合体およびそれらからなるワクチン
AU47900/93A AU683421B2 (en) 1992-07-30 1993-07-28 Conjugates of poorly immunogenic antigens and synthetic peptide carriers and vaccines comprising them
FI950405A FI950405L (fi) 1992-07-30 1993-07-28 Heikosti immunogeenisten antigeenien ja synteettisten peptidikantajien konjugaatit sekä niitä sisältävät rokotteet
SK112-95A SK11295A3 (en) 1992-07-30 1993-07-28 Conjugates of poorly immunogenic antigens and synthetic peptide carriers and vaccines comprising them
EP93918458A EP0658120B1 (en) 1992-07-30 1993-07-28 Conjugates of poorly immunogenic antigens and synthetic peptide carriers and vaccines comprising them
NZ255143A NZ255143A (en) 1992-07-30 1993-07-28 Conjugates of poorly immunogenic antigens (peptides, proteins or polysaccharides) with a carrier peptide of t-cell epitope from human heat shock protein
BR9306820A BR9306820A (pt) 1992-07-30 1993-07-28 Conjugado de um antígeno fracamente imunogênico e um veículo peptideo sintetico vacina processos para melhorar a imunogenicidade de uma molecula de antigeno fracamente imunogenico e para imunizar um hospedeiro mamífero
NO950328A NO950328L (no) 1992-07-30 1995-01-27 Konjugater med svake immunogene antigener og syntetiske peptidbærere og vaksiner som inneholder disse

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL102687A IL102687A (en) 1992-07-30 1992-07-30 Conjugates of poorly immunogenic antigens and synthetic pepide carriers and vaccines comprising them

Publications (2)

Publication Number Publication Date
IL102687A0 IL102687A0 (en) 1993-01-14
IL102687A true IL102687A (en) 1997-06-10

Family

ID=11063877

Family Applications (1)

Application Number Title Priority Date Filing Date
IL102687A IL102687A (en) 1992-07-30 1992-07-30 Conjugates of poorly immunogenic antigens and synthetic pepide carriers and vaccines comprising them

Country Status (18)

Country Link
EP (1) EP0658120B1 (pt)
JP (1) JP4087898B2 (pt)
KR (1) KR100290632B1 (pt)
AT (1) ATE188612T1 (pt)
AU (1) AU683421B2 (pt)
BR (1) BR9306820A (pt)
CA (1) CA2141454C (pt)
CZ (1) CZ22995A3 (pt)
DE (1) DE69327587T2 (pt)
FI (1) FI950405L (pt)
HU (1) HU218425B (pt)
IL (1) IL102687A (pt)
NO (1) NO950328L (pt)
NZ (1) NZ255143A (pt)
PL (1) PL174082B1 (pt)
RU (1) RU95105991A (pt)
SK (1) SK11295A3 (pt)
WO (1) WO1994003208A1 (pt)

Families Citing this family (223)

* Cited by examiner, † Cited by third party
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DE19821859A1 (de) * 1998-05-15 1999-12-09 M Alexander Schmidt Darstellung immunogener (Kapsel-)Polysaccharid-Konjugate durch orientierte Kupplung synthetischer T-Zell-Epitope zur Erzeugung von Vakzinen gegen N.meningitidis
KR20020013470A (ko) * 1998-10-02 2002-02-20 미우라 아키라 세포성 면역의 유도방법 및 세포성 면역이 유도된 세포
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EP0658120A1 (en) 1995-06-21
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