ATE397456T1 - Enterokokkus antigene und vakzine - Google Patents
Enterokokkus antigene und vakzineInfo
- Publication number
- ATE397456T1 ATE397456T1 AT98951058T AT98951058T ATE397456T1 AT E397456 T1 ATE397456 T1 AT E397456T1 AT 98951058 T AT98951058 T AT 98951058T AT 98951058 T AT98951058 T AT 98951058T AT E397456 T1 ATE397456 T1 AT E397456T1
- Authority
- AT
- Austria
- Prior art keywords
- antigen
- carrier
- vaccines
- antigens
- galactose
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Gram-positive bacteria
- C07K16/1275—Streptococcus (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/831—Drug, bio-affecting and body treating compositions involving capsular polysaccharide of bacterium, e.g. polyribosyl ribitol phosphate
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/949,757 US6756361B1 (en) | 1997-10-14 | 1997-10-14 | Enterococcus antigens and vaccines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE397456T1 true ATE397456T1 (de) | 2008-06-15 |
Family
ID=25489514
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98951058T ATE397456T1 (de) | 1997-10-14 | 1998-10-14 | Enterokokkus antigene und vakzine |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US6756361B1 (de) |
| EP (3) | EP2269635A1 (de) |
| JP (2) | JP2001519402A (de) |
| AT (1) | ATE397456T1 (de) |
| AU (1) | AU754890B2 (de) |
| BR (1) | BR9813254A (de) |
| CA (1) | CA2306476A1 (de) |
| CY (1) | CY1108307T1 (de) |
| DE (1) | DE69839587D1 (de) |
| DK (1) | DK1028749T3 (de) |
| ES (1) | ES2308818T3 (de) |
| NZ (1) | NZ504501A (de) |
| PT (1) | PT1028749E (de) |
| WO (1) | WO1999018996A1 (de) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6905670B2 (en) | 1995-03-28 | 2005-06-14 | The General Hospital Corporation | Methods of screening compounds useful for prevention of infection or pathogenicity |
| KR100217772B1 (ko) * | 1996-09-03 | 1999-09-01 | 최진호 | 조명기기의 램프 과열방지 장치 및 방법 |
| US6756361B1 (en) * | 1997-10-14 | 2004-06-29 | Nabi | Enterococcus antigens and vaccines |
| US7078584B2 (en) | 2000-03-17 | 2006-07-18 | The General Hospital Corporation | Salmonella typhimurium-infected Caenorhabditis elegans for identifying inhibitors of infection |
| US7112716B2 (en) | 2000-04-06 | 2006-09-26 | The General Hospital Corporation | Methods for screening and identifying host pathogen defense genes |
| US6710403B2 (en) | 2002-07-30 | 2004-03-23 | Fairchild Semiconductor Corporation | Dual trench power MOSFET |
| AU2004242842B2 (en) * | 2003-05-30 | 2011-11-03 | Intercell Ag | Enterococcus antigens |
| EP1768662A2 (de) | 2004-06-24 | 2007-04-04 | Novartis Vaccines and Diagnostics, Inc. | Immunstimulatoren kleiner moleküle und assays für deren nachweis |
| WO2006078318A2 (en) | 2004-07-29 | 2006-07-27 | Novartis Vaccines And Diagnostics Inc. | Immunogenic compositions for gram positive bacteria such as streptococcus agalactiae |
| KR20070104590A (ko) * | 2005-01-10 | 2007-10-26 | 나비 바이오파마슈티컬즈 | 스타필로코쿠스 아우레우스 감염을 치료하는 방법 |
| WO2007047749A1 (en) | 2005-10-18 | 2007-04-26 | Novartis Vaccines And Diagnostics Inc. | Mucosal and systemic immunizations with alphavirus replicon particles |
| CA2630220C (en) | 2005-11-22 | 2020-10-13 | Doris Coit | Norovirus and sapovirus antigens |
| EP2368570A3 (de) | 2006-01-18 | 2012-05-02 | University Of Chicago | Zusammensetzungen und Verfahren in Verbindung mit Stayphylokokken-Bakterienproteinen |
| EP2010537B1 (de) | 2006-03-23 | 2011-12-28 | Novartis AG | Imidazochinoxalinverbindungen als immunmodulatoren |
| EP2010530A2 (de) * | 2006-03-23 | 2009-01-07 | Novartis AG | Herstellungsverfahren für imidazolhaltige verbindungen |
| EP2007765B1 (de) * | 2006-03-23 | 2012-06-27 | Novartis AG | Immunstimulierende verbindungen |
| MX2008014977A (es) | 2006-06-06 | 2008-12-05 | Crucell Holland Bv | Moleculas de union humanas que tienen actividad exterminadora contra estafilococos y uso de las mismas. |
| JP5586952B2 (ja) | 2006-06-06 | 2014-09-10 | クルセル ホランド ベー ヴェー | 腸球菌に対する殺活性を有するヒトの結合分子及びその使用方法 |
| AU2008292897B2 (en) | 2007-08-31 | 2015-01-22 | University Of Chicago | Methods and compositions related to immunizing against staphylococcal lung diseases and conditions |
| CA2699513C (en) | 2007-09-12 | 2018-03-13 | Novartis Ag | Gas57 mutant antigens and gas57 antibodies |
| PT2235046E (pt) | 2007-12-21 | 2012-10-26 | Novartis Ag | Formas mutantes de estreptolisina o |
| US20110262477A1 (en) | 2008-10-06 | 2011-10-27 | University Of Chicago | Compositions and Methods Related to Bacterial EAP, EMP, and/or ADSA Proteins |
| CN102481349B (zh) | 2009-01-12 | 2014-10-15 | 诺华股份有限公司 | 抗革兰氏阳性细菌疫苗中的Cna_B结构域 |
| HRP20160274T1 (hr) | 2009-04-03 | 2016-04-08 | University Of Chicago | Pripravci i metode vezane za varijante proteina a (spa) |
| EP2443250B8 (de) | 2009-06-16 | 2016-09-21 | GlaxoSmithKline Biologicals SA | Komplement-vermittelte antikörper-abhängige und opsonische bakterienassays mit hohem durchlauf |
| US10266585B2 (en) | 2009-08-28 | 2019-04-23 | The Board Of Regents Of The Univerity Of Texas System | Methods of treating brain injury |
| MX2012008426A (es) * | 2010-01-19 | 2012-11-23 | Universitaetsklinikum Freiburg | Componentes de pared celular de enterococo y uso antibacteriano de los mismos. |
| US8808699B2 (en) | 2010-04-05 | 2014-08-19 | The University Of Chicago | Compositions and methods related to protein A (SpA) antibodies as an enhancer of immune response |
| KR20130121699A (ko) | 2010-05-28 | 2013-11-06 | 테트리스 온라인, 인코포레이티드 | 상호작용 혼성 비동기 컴퓨터 게임 기반구조 |
| EP2588120B1 (de) | 2010-07-02 | 2017-11-15 | The University of Chicago | Zusammensetzungen und verfahren bezüglich protein-a (spa)-varianten |
| US9095540B2 (en) | 2010-09-09 | 2015-08-04 | The University Of Chicago | Methods and compositions involving protective staphylococcal antigens |
| AU2011315920B2 (en) | 2010-10-15 | 2016-04-28 | The Board Of Regents Of The University Of Texas System | Antibodies that bind amyloid oligomers |
| US8945588B2 (en) | 2011-05-06 | 2015-02-03 | The University Of Chicago | Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides |
| DK2526951T3 (en) * | 2011-05-27 | 2016-01-04 | Universitätsklinikum Freiburg | Rhamnopolysaccharid from Enterococcus faecium clone 17 complex and uses thereof |
| WO2013025834A2 (en) | 2011-08-15 | 2013-02-21 | The University Of Chicago | Compositions and methods related to antibodies to staphylococcal protein a |
| HRP20201127T1 (hr) | 2012-04-26 | 2020-11-27 | University Of Chicago | Antigeni stafilokokne koagulaze i metode primjene istih |
| JP6251730B2 (ja) | 2012-04-26 | 2017-12-20 | ザ・ユニバーシティ・オブ・シカゴThe University Of Chicago | 黄色ブドウ球菌(staphylococcusaureus)疾患の間にコアグラーゼ活性を中和する抗体に関連した組成物および方法 |
| EP2872535A1 (de) * | 2012-07-16 | 2015-05-20 | Pfizer Inc. | Saccharide und verwendungen davon |
| WO2014116721A1 (en) | 2013-01-22 | 2014-07-31 | The Arizona Board Of Regents For And On Behalf Of Arizona State University | Geminiviral vector for expression of rituximab |
| EP2915543B1 (de) * | 2014-03-04 | 2018-05-09 | Albert-Ludwigs-Universität Freiburg | Aus Enterococcus abgeleitete Polypeptide und Verwendung davon zur Impfung und Erstellung von therapeutischen Antikörpern |
| US11246924B2 (en) | 2016-04-01 | 2022-02-15 | Duke University | Alpha-helical peptide nanofibers as a self-adjuvanting vaccine platform |
| US11413336B2 (en) | 2018-03-23 | 2022-08-16 | Board Of Regents, The University Of Texas System | Coccidioides antigens and methods of their use |
| CA3139981A1 (en) | 2019-05-14 | 2020-11-19 | The University Of Chicago | Methods and compositions comprising staphylococcus protein a (spa) variants |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2466251B1 (fr) * | 1979-10-03 | 1983-03-18 | Agronomique Inst Nat Rech | Vaccin animal anticolibacillaire, obtention et application |
| US4439422A (en) | 1980-01-02 | 1984-03-27 | Research Corporation | Group B Streptococcus antigens and vaccines |
| US4331647A (en) | 1980-03-03 | 1982-05-25 | Goldenberg Milton David | Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers |
| US4444879A (en) * | 1981-01-29 | 1984-04-24 | Science Research Center, Inc. | Immunoassay with article having support film and immunological counterpart of analyte |
| JPS5927833A (ja) * | 1982-08-06 | 1984-02-14 | Advance Res & Dev Co Ltd | コレステロール乃至トリグリセリド低下剤 |
| GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
| FR2546756B1 (fr) * | 1983-06-03 | 1985-11-29 | Centre Nat Rech Scient | Nouveaux derives immunostimulants, leur preparation et leur application comme medicament |
| US4761283A (en) * | 1983-07-05 | 1988-08-02 | The University Of Rochester | Immunogenic conjugates |
| JPS6028401A (ja) | 1983-07-27 | 1985-02-13 | Advance Res & Dev Co Ltd | トリグリセリド低下活性多糖類 |
| US4626502A (en) * | 1984-01-27 | 1986-12-02 | Abbott Laboratories | Method for exposing bacterial antigen in bacterial cells assay using same |
| US4695624A (en) | 1984-05-10 | 1987-09-22 | Merck & Co., Inc. | Covalently-modified polyanionic bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins with bigeneric spacers, and methods of preparing such polysaccharides and conjugates and of confirming covalency |
| GB8414273D0 (en) * | 1984-06-05 | 1984-07-11 | Oxoid Ltd | Identifying streptococcal grouping |
| JPS615022A (ja) * | 1984-06-19 | 1986-01-10 | Advance Res & Dev Co Ltd | 腸内細菌叢改善剤 |
| GB8517895D0 (en) * | 1985-07-16 | 1985-08-21 | Technology Licence Co Ltd | Monoclonal antibodies |
| US4695524A (en) * | 1986-05-21 | 1987-09-22 | Xerox Corporation | Process for ultra high quality images with magnetic developer composition |
| US5143845A (en) * | 1986-09-03 | 1992-09-01 | Toa Pharmaceutical Co., Ltd. | Mixture of saccarifying lactic acid producing and butyric acid producing bacteria |
| AU8108587A (en) * | 1986-10-08 | 1988-05-06 | David Bernstein | Method for exposing group a streptococcal antigens and an improved diagnostic test for the identification of group a streptococci |
| US5032505A (en) | 1988-11-21 | 1991-07-16 | Chembiomed, Ltd. | Inhibitors for glycosaminosyl transferase V |
| US5175279A (en) * | 1989-01-19 | 1992-12-29 | Hakuto Co., Ltd. | Polysaccharide, and water absorbent, moisture absorbent or humectant and thickening agent chiefly made of the polysaccharide |
| US5032401A (en) * | 1989-06-15 | 1991-07-16 | Alpha Beta Technology | Glucan drug delivery system and adjuvant |
| US5010062A (en) * | 1989-09-25 | 1991-04-23 | Vanderbilt University | Therapeutic agent and method of inhibiting vascularization of tumors |
| CA2059692C (en) | 1991-01-28 | 2004-11-16 | Peter J. Kniskern | Pneumoccoccal polysaccharide conjugate vaccine |
| US5858728A (en) * | 1991-03-13 | 1999-01-12 | Common Services Agency | Monoclonal antibody against LPS core |
| US5225331A (en) * | 1991-04-25 | 1993-07-06 | National Research Council Of Canada | Immunoassay for detecting group b streptococcus |
| US5205917A (en) * | 1991-05-07 | 1993-04-27 | Glyko, Inc. | Fluorophore assisted carbohydrate electrophoresis diagnosis |
| JP3201523B2 (ja) * | 1991-08-23 | 2001-08-20 | アルバータ リサーチ カウンスル | ヒト受容体における抗体−仲介異種移植拒絶を弱めるための方法および組成物 |
| US5478557A (en) * | 1992-07-29 | 1995-12-26 | The United States Of America, As Represented By The Secretary Of Agriculture | Probiotic for control of salmonella |
| RU2101029C1 (ru) * | 1992-11-26 | 1998-01-10 | Товарищество с ограниченной ответственностью "ХИМЭК" | Способ получения препарата для идентификации стрептококка группы д |
| GB9310468D0 (en) * | 1993-05-20 | 1993-07-07 | Oxford Glycosystems Ltd | Sugar complexes |
| US5367058A (en) * | 1993-08-25 | 1994-11-22 | Becton, Dickinson And Company | Modified antibodies with increased affinity |
| JPH0782158A (ja) * | 1993-09-16 | 1995-03-28 | Yakult Honsha Co Ltd | 抗腫瘍剤 |
| JP2717497B2 (ja) * | 1993-12-28 | 1998-02-18 | 不二ラテックス株式会社 | 酸性多糖類被覆コンドーム |
| GB9401689D0 (en) * | 1994-01-28 | 1994-03-23 | Univ Manchester | Diagnosis and treatment of endocarditis |
| US5866135A (en) * | 1994-04-21 | 1999-02-02 | North American Vaccine, Inc. | Group A streptococcal polysaccharide immunogenic compositions and methods |
| US5489302A (en) * | 1994-05-24 | 1996-02-06 | Skottun; Bernt C. | Accommodating intraocular lens |
| JPH0827010A (ja) * | 1994-07-19 | 1996-01-30 | Nichinichi Seiyaku Kk | 制癌免疫療法剤 |
| US5700787A (en) * | 1994-09-02 | 1997-12-23 | Brigham & Women's Hospital, Inc. | Capsular polysaccharide immunomodulator |
| US5871751A (en) * | 1994-10-12 | 1999-02-16 | The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | Renibacterium salmoninarum vaccine and method for its preparation |
| US5569366A (en) * | 1995-01-27 | 1996-10-29 | Beckman Instruments, Inc. | Fluorescent labelled carbohydrates and their analysis |
| EP0775490A4 (de) * | 1995-06-05 | 1998-06-03 | Tayca Corp | Immunpotentiator |
| US5695768A (en) * | 1995-06-07 | 1997-12-09 | Alberta Research Council | Immunostimulating activity of Streptococcus pneumoniae serotype 8 oligosaccharides |
| DE19524515A1 (de) * | 1995-07-05 | 1997-01-09 | Deutsches Krebsforsch | Saccharid-Konjugate |
| WO1999008705A1 (en) * | 1997-08-20 | 1999-02-25 | Brigham And Women's Hospital | Capsular polysaccharides from enterococci |
| US6722062B2 (en) * | 1997-08-20 | 2004-04-20 | The Brigham And Women's Hospital, Inc. | Capsular polysaccharides from enterococci |
| US6756361B1 (en) * | 1997-10-14 | 2004-06-29 | Nabi | Enterococcus antigens and vaccines |
| US7030101B2 (en) * | 1998-09-14 | 2006-04-18 | Nabi Biopharmaceuticals | Compositions of β-glucans and specific antibodies |
| CA2344166C (en) * | 1998-09-14 | 2008-11-18 | Nabi | Compositions of .beta.-glucans and specific igiv |
| ATE439857T1 (de) * | 1999-03-12 | 2009-09-15 | Univ Massachusetts | Lipoglykan zusammensetzungen und methoden zur behandlung von parasitischen infektionen |
| US6720160B2 (en) * | 2001-10-11 | 2004-04-13 | Helica Biosystems, Inc. | Method for simultaneous detection of multiple microbial antigens in biological specimens from mastitic animals |
-
1997
- 1997-10-14 US US08/949,757 patent/US6756361B1/en not_active Expired - Fee Related
-
1998
- 1998-10-14 PT PT98951058T patent/PT1028749E/pt unknown
- 1998-10-14 AU AU96949/98A patent/AU754890B2/en not_active Ceased
- 1998-10-14 EP EP10178313A patent/EP2269635A1/de not_active Withdrawn
- 1998-10-14 EP EP08008590A patent/EP1970073A1/de not_active Withdrawn
- 1998-10-14 ES ES98951058T patent/ES2308818T3/es not_active Expired - Lifetime
- 1998-10-14 DE DE69839587T patent/DE69839587D1/de not_active Expired - Lifetime
- 1998-10-14 DK DK98951058T patent/DK1028749T3/da active
- 1998-10-14 EP EP98951058A patent/EP1028749B1/de not_active Expired - Lifetime
- 1998-10-14 BR BR9813254-7A patent/BR9813254A/pt not_active IP Right Cessation
- 1998-10-14 CA CA002306476A patent/CA2306476A1/en not_active Abandoned
- 1998-10-14 JP JP2000515628A patent/JP2001519402A/ja active Pending
- 1998-10-14 AT AT98951058T patent/ATE397456T1/de active
- 1998-10-14 WO PCT/US1998/021561 patent/WO1999018996A1/en not_active Ceased
- 1998-10-14 NZ NZ504501A patent/NZ504501A/en not_active IP Right Cessation
-
2004
- 2004-06-28 US US10/876,758 patent/US7291343B2/en not_active Expired - Fee Related
-
2008
- 2008-09-02 CY CY20081100934T patent/CY1108307T1/el unknown
-
2009
- 2009-05-18 JP JP2009119505A patent/JP2009227680A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP1028749B1 (de) | 2008-06-04 |
| DK1028749T3 (da) | 2008-09-01 |
| US7291343B2 (en) | 2007-11-06 |
| WO1999018996A1 (en) | 1999-04-22 |
| AU754890B2 (en) | 2002-11-28 |
| PT1028749E (pt) | 2008-09-04 |
| JP2009227680A (ja) | 2009-10-08 |
| WO1999018996B1 (en) | 1999-06-03 |
| ES2308818T3 (es) | 2008-12-01 |
| BR9813254A (pt) | 2001-11-20 |
| EP2269635A1 (de) | 2011-01-05 |
| JP2001519402A (ja) | 2001-10-23 |
| US20050008658A1 (en) | 2005-01-13 |
| CA2306476A1 (en) | 1999-04-22 |
| CY1108307T1 (el) | 2014-02-12 |
| AU9694998A (en) | 1999-05-03 |
| US6756361B1 (en) | 2004-06-29 |
| NZ504501A (en) | 2003-09-26 |
| EP1028749A4 (de) | 2003-03-12 |
| EP1028749A1 (de) | 2000-08-23 |
| DE69839587D1 (de) | 2008-07-17 |
| EP1970073A1 (de) | 2008-09-17 |
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