IL108937A - P Solid hydroxyacetanylide and compressible L-cysteine for the preparation of formulated pharmaceutical preparations - Google Patents

P Solid hydroxyacetanylide and compressible L-cysteine for the preparation of formulated pharmaceutical preparations

Info

Publication number
IL108937A
IL108937A IL10893794A IL10893794A IL108937A IL 108937 A IL108937 A IL 108937A IL 10893794 A IL10893794 A IL 10893794A IL 10893794 A IL10893794 A IL 10893794A IL 108937 A IL108937 A IL 108937A
Authority
IL
Israel
Prior art keywords
mixture
hydroxyacetanilide
cysteine
composition
solid
Prior art date
Application number
IL10893794A
Other languages
English (en)
Hebrew (he)
Other versions
IL108937A0 (en
Original Assignee
British Tech Group
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by British Tech Group filed Critical British Tech Group
Publication of IL108937A0 publication Critical patent/IL108937A0/xx
Publication of IL108937A publication Critical patent/IL108937A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL10893794A 1993-03-12 1994-03-11 P Solid hydroxyacetanylide and compressible L-cysteine for the preparation of formulated pharmaceutical preparations IL108937A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939305058A GB9305058D0 (en) 1993-03-12 1993-03-12 Pharmaceutical compositions

Publications (2)

Publication Number Publication Date
IL108937A0 IL108937A0 (en) 1994-06-24
IL108937A true IL108937A (en) 1999-10-28

Family

ID=10731916

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10893794A IL108937A (en) 1993-03-12 1994-03-11 P Solid hydroxyacetanylide and compressible L-cysteine for the preparation of formulated pharmaceutical preparations

Country Status (20)

Country Link
US (2) US5716991A (es)
EP (2) EP0689434B1 (es)
JP (1) JPH08507305A (es)
KR (1) KR960700701A (es)
CN (1) CN1118989A (es)
AT (2) ATE221777T1 (es)
AU (1) AU674934B2 (es)
BR (1) BR9406227A (es)
CA (1) CA2157921C (es)
DE (2) DE69434600T2 (es)
DK (1) DK0689434T3 (es)
ES (2) ES2176238T3 (es)
GB (2) GB9305058D0 (es)
IL (1) IL108937A (es)
NO (1) NO318493B1 (es)
NZ (1) NZ262168A (es)
PT (1) PT689434E (es)
SG (1) SG48344A1 (es)
WO (1) WO1994020086A1 (es)
ZA (1) ZA941674B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6048540A (en) * 1997-01-29 2000-04-11 Chong Kun Dang Corp. Acetamenophen composition with reduced liver toxicity
WO2001068069A2 (en) * 2000-03-15 2001-09-20 King's College London Pharmaceutical composition comprising paracetamol
KR100379155B1 (ko) * 2000-07-18 2003-04-08 삼진제약주식회사 새로운 진통제 조성물
US6623754B2 (en) * 2001-05-21 2003-09-23 Noveon Ip Holdings Corp. Dosage form of N-acetyl cysteine
US20080188439A1 (en) * 2006-10-26 2008-08-07 Salhanick Steven D Directed metabolism of compounds by glucuronidation and sulfonation donors to decrease toxicity
ITMI20080187A1 (it) * 2008-02-07 2009-08-08 Velleja Res Srl Formulazioni di amminoacidi per la prevenzione del danno epatico da paracetamolo
WO2011008976A1 (en) * 2009-07-15 2011-01-20 Leland Stanford, The Board Of Trustees Of The Junior University N-acetyl cysteine compositions and methods to improved the therapeutic efficacy of acetaminophen
ITMI20130874A1 (it) * 2013-05-29 2014-11-30 Zambon Spa Compresse deglutibili di n-acetilcisteina

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3200039A (en) * 1962-05-28 1965-08-10 Pfizer & Co C Non-granulated tablets with 20% sorbitol in a particle size of from about 100mu to about 2000mu
GB1287431A (en) * 1969-04-16 1972-08-31 Aspro Nicholas Ltd Improvements in pharmaceutical formulations
GB1390032A (en) * 1971-08-27 1975-04-09 Sterling Winthrop Group Ltd Pharmaceutical compositions
GB1410909A (en) * 1971-10-26 1975-10-22 Sterling Winthrop Group Ltd Pharmaceutical compositions
GB1463505A (en) * 1973-11-21 1977-02-02 Nat Res Dev Pharmaceutical compositions
GB1583602A (en) * 1977-05-26 1981-01-28 Sterwin Ag N-acetyl-para-aminophenyl-n'-acetyl-amino-thioalkanoic acid ester derivatives
DE3173600D1 (en) * 1980-05-20 1986-03-13 Mallinckrodt Inc Spray dried n-acetyl-p-aminophenol compositions and method for manufacture thereof
US4439453A (en) * 1980-12-22 1984-03-27 Monsanto Company Directly compressible acetaminophen granulation
IE55579B1 (en) * 1982-07-06 1990-11-07 Sterwin Ag Processes for preparing tablets by a modified'wet-granulation'technique
US4600579A (en) * 1983-06-07 1986-07-15 Mallinckrodt, Inc. N-acetyl-p-aminophenol compositions containing partially gelatinized starch and method for preparing same
US4760093A (en) * 1986-10-21 1988-07-26 American Home Products Corporation (Del.) Spray dried acetaminophen
US5037658A (en) * 1989-09-14 1991-08-06 Hoechst-Roussel Pharmaceuticals, Inc. Direct dry compressible acetaminophen composition
DK0481294T4 (da) * 1990-10-19 2001-06-18 Spirig Ag Fast, hurtigt-opløseligt lægemiddelpræparat indeholdende N-acetylcystein
US5474757A (en) * 1992-10-16 1995-12-12 Rutgers University Prevention of acetaminophen overdose toxicity with organosulfur compounds
FR2708602B1 (fr) * 1993-08-02 1995-10-06 Oreal Procédé d'extraction des composés malodorants présents dans une formulation contenant au moins un composé comportant un groupe thiol et compositions désodorisées ainsi obtenues.
US5370878A (en) * 1993-09-30 1994-12-06 Hallmark Pharmaceuticals, Inc. Method for preparing a direct compression granulated acetaminophen composition
JPH07130367A (ja) * 1993-10-29 1995-05-19 Sony Corp リチウム二次電池用正極活物質の製造方法

Also Published As

Publication number Publication date
DE69431151D1 (de) 2002-09-12
JPH08507305A (ja) 1996-08-06
EP0689434A1 (en) 1996-01-03
AU674934B2 (en) 1997-01-16
NZ262168A (en) 1997-05-26
CA2157921A1 (en) 1994-09-15
DE69431151T2 (de) 2002-12-12
CN1118989A (zh) 1996-03-20
ATE314842T1 (de) 2006-02-15
ZA941674B (en) 1995-09-11
DE69434600D1 (de) 2006-03-30
IL108937A0 (en) 1994-06-24
NO953515D0 (no) 1995-09-07
DE69434600T2 (de) 2006-08-24
EP1210939A2 (en) 2002-06-05
ATE221777T1 (de) 2002-08-15
EP0689434B1 (en) 2002-08-07
BR9406227A (pt) 1995-12-12
CA2157921C (en) 2006-07-11
WO1994020086A1 (en) 1994-09-15
GB9404427D0 (en) 1994-04-20
EP1210939B1 (en) 2006-01-04
KR960700701A (ko) 1996-02-24
GB2276319A (en) 1994-09-28
EP1210939A3 (en) 2002-08-07
NO953515L (no) 1995-09-07
SG48344A1 (en) 1998-04-17
GB2276319B (en) 1997-01-15
ES2254541T3 (es) 2006-06-16
DK0689434T3 (da) 2002-12-02
US5716991A (en) 1998-02-10
AU6148794A (en) 1994-09-26
PT689434E (pt) 2002-12-31
ES2176238T3 (es) 2002-12-01
US5852055A (en) 1998-12-22
NO318493B1 (no) 2005-03-29
GB9305058D0 (en) 1993-04-28

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Legal Events

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