IL110296A - Imidazole compounds process for their preparation and pharmaceutical compositions containing them - Google Patents

Imidazole compounds process for their preparation and pharmaceutical compositions containing them

Info

Publication number: IL110296A
Authority: IL; Israel
Prior art keywords: preparation; pharmaceutical compositions; compositions containing; imidazole compounds; compounds process
Prior art date: 1993-07-16

Application number

IL11029694A

Other languages

English (en)

Other versions

IL110296A0 (en

Original Assignee

Smithkline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-07-16

Filing date

1994-07-12

Publication date

1999-12-31

1994-07-12 Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp

1994-10-21 Publication of IL110296A0 publication Critical patent/IL110296A0/xx

1999-12-31 Publication of IL110296A publication Critical patent/IL110296A/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Physical Education & Sports Medicine (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Virology (AREA)
Orthopedic Medicine & Surgery (AREA)
Rheumatology (AREA)
Neurology (AREA)
Hematology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Obesity (AREA)
Immunology (AREA)
Emergency Medicine (AREA)
Tropical Medicine & Parasitology (AREA)
Molecular Biology (AREA)
AIDS & HIV (AREA)
Hospice & Palliative Care (AREA)
Toxicology (AREA)
Endocrinology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)

IL11029694A 1993-07-16 1994-07-12 Imidazole compounds process for their preparation and pharmaceutical compositions containing them IL110296A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US9273393A	1993-07-16	1993-07-16

Publications (2)

Publication Number	Publication Date
IL110296A0 IL110296A0 (en)	1994-10-21
IL110296A true IL110296A (en)	1999-12-31

Family

ID=22234840

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IL11029694A IL110296A (en)	1993-07-16	1994-07-12	Imidazole compounds process for their preparation and pharmaceutical compositions containing them
IL12431898A IL124318A0 (en)	1993-07-16	1998-05-04	Starting material for the preparation of imidazole compounds

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
IL12431898A IL124318A0 (en)	1993-07-16	1998-05-04	Starting material for the preparation of imidazole compounds

Country Status (31)

Country	Link
EP (5)	EP1291346B1 (fr)
JP (4)	JPH09500137A (fr)
CN (2)	CN1050126C (fr)
AP (1)	AP484A (fr)
AT (2)	ATE236896T1 (fr)
AU (1)	AU694130C (fr)
BR (2)	BR9407079A (fr)
CA (1)	CA2167311A1 (fr)
CZ (1)	CZ11996A3 (fr)
DE (2)	DE69432463T2 (fr)
DK (1)	DK0708768T3 (fr)
DZ (1)	DZ1798A1 (fr)
ES (2)	ES2237650T3 (fr)
FI (1)	FI960177A0 (fr)
HK (3)	HK1049658A1 (fr)
HU (1)	HUT75313A (fr)
IL (2)	IL110296A (fr)
MA (1)	MA23270A1 (fr)
MY (1)	MY116478A (fr)
NO (4)	NO316881B1 (fr)
NZ (2)	NZ329994A (fr)
PL (4)	PL181721B1 (fr)
PT (1)	PT708768E (fr)
RU (1)	RU2140918C1 (fr)
SG (1)	SG52368A1 (fr)
SI (1)	SI0708768T1 (fr)
SK (1)	SK282342B6 (fr)
TW (1)	TW330934B (fr)
UA (1)	UA63875C2 (fr)
WO (1)	WO1995002591A1 (fr)
ZA (1)	ZA945193B (fr)

Families Citing this family (93)

* Cited by examiner, † Cited by third party
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WO1998007425A1 (fr)	1996-08-21	1998-02-26	Smithkline Beecham Corporation	Composes d'imidazole, compositions les contenant et leur utilisation
US5945418A (en) *	1996-12-18	1999-08-31	Vertex Pharmaceuticals Incorporated	Inhibitors of p38
US6608060B1 (en)	1996-12-18	2003-08-19	Vertex Pharmaceuticals Incorporated	Inhibitors of p38
US6147080A (en) *	1996-12-18	2000-11-14	Vertex Pharmaceuticals Incorporated	Inhibitors of p38
US5929076A (en) *	1997-01-10	1999-07-27	Smithkline Beecham Corporation	Cycloalkyl substituted imidazoles
US6187799B1 (en)	1997-05-23	2001-02-13	Onyx Pharmaceuticals	Inhibition of raf kinase activity using aryl ureas
CA2294057A1 (fr)	1997-06-13	1998-12-17	Smithkline Beecham Corporation	Nouveaux composes de pyrazole et de pyrazoline substitues
AU8154998A (en)	1997-06-19	1999-01-04	Smithkline Beecham Corporation	Novel aryloxy substituted pyrimidine imidazole compounds
US7301021B2 (en)	1997-07-02	2007-11-27	Smithkline Beecham Corporation	Substituted imidazole compounds
US6489325B1 (en)	1998-07-01	2002-12-03	Smithkline Beecham Corporation	Substituted imidazole compounds
TW517055B (en) *	1997-07-02	2003-01-11	Smithkline Beecham Corp	Novel substituted imidazole compounds
WO1999001452A1 (fr)	1997-07-02	1999-01-14	Smithkline Beecham Corporation	Nouveaux imidazoles cycloalkyle-substitues
US6562832B1 (en)	1997-07-02	2003-05-13	Smithkline Beecham Corporation	Substituted imidazole compounds
WO1999017776A1 (fr)	1997-10-08	1999-04-15	Smithkline Beecham Corporation	Nouveaux composes substitues de cycloalcenyle
EP1021173A1 (fr) *	1997-10-10	2000-07-26	Imperial College Innovations Limited	Emploi de composes de csaid?tm pour le traitement des contractions uterines
JP3337992B2 (ja) *	1997-11-04	2002-10-28	ファイザー製薬株式会社	５−置換ピコリン酸化合物及びその製造方法
WO1999032121A1 (fr) *	1997-12-19	1999-07-01	Smithkline Beecham Corporation	.0mposes d'imidazole heteroaryle substitues, leurs compositions et usages pharmaceutiques
US7517880B2 (en)	1997-12-22	2009-04-14	Bayer Pharmaceuticals Corporation	Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas
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CN1548436A (zh)	1998-05-22	2004-11-24	ʷ��˿��ȳ�ķ��޹�˾	新的2-烷基取代咪唑化合物
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WO2000025791A1 (fr)	1998-11-04	2000-05-11	Smithkline Beecham Corporation	Pyrazines substitues pyridin-4-yle ou pyrimidin-4-yle
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WO2000042012A1 (fr)	1999-01-13	2000-07-20	Bayer Corporation	DIPHENYLUREES A SUBSTITUANTS φ-CARBOXYARYLES, INHIBITRICES DE KINASE RAF
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ATE305787T1 (de)	1999-11-23	2005-10-15	Smithkline Beecham Corp	3,4-dihydro-(1h)chinazolin-2-on-verbindungen als csbp/p39-kinase-inhibitoren
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1994
- 1994-07-12 IL IL11029694A patent/IL110296A/xx not_active IP Right Cessation
- 1994-07-13 AP APAP/P/1994/000654A patent/AP484A/en active
- 1994-07-13 DZ DZ940081A patent/DZ1798A1/fr active
- 1994-07-14 MY MYPI94001844A patent/MY116478A/en unknown
- 1994-07-14 MA MA23584A patent/MA23270A1/fr unknown
- 1994-07-15 EP EP02079534A patent/EP1291346B1/fr not_active Expired - Lifetime
- 1994-07-15 EP EP94923503A patent/EP0708768B1/fr not_active Expired - Lifetime
- 1994-07-15 PL PL94332408A patent/PL181721B1/pl unknown
- 1994-07-15 CA CA002167311A patent/CA2167311A1/fr not_active Abandoned
- 1994-07-15 PL PL94332405A patent/PL181723B1/pl unknown
- 1994-07-15 JP JP7504744A patent/JPH09500137A/ja active Pending
- 1994-07-15 DE DE69432463T patent/DE69432463T2/de not_active Expired - Fee Related
- 1994-07-15 HU HU9503855A patent/HUT75313A/hu unknown
- 1994-07-15 EP EP02076580A patent/EP1227091A3/fr not_active Withdrawn
- 1994-07-15 EP EP02076582A patent/EP1227092A3/fr not_active Withdrawn
- 1994-07-15 PT PT94923503T patent/PT708768E/pt unknown
- 1994-07-15 SI SI9430449T patent/SI0708768T1/xx unknown
- 1994-07-15 NZ NZ329994A patent/NZ329994A/xx unknown
- 1994-07-15 ES ES02079534T patent/ES2237650T3/es not_active Expired - Lifetime
- 1994-07-15 EP EP02076581A patent/EP1229035A1/fr not_active Withdrawn
- 1994-07-15 DE DE69434316T patent/DE69434316T2/de not_active Expired - Fee Related
- 1994-07-15 ES ES94923503T patent/ES2197167T3/es not_active Expired - Lifetime
- 1994-07-15 NZ NZ269457A patent/NZ269457A/en unknown
- 1994-07-15 PL PL94332406A patent/PL181694B1/pl unknown
- 1994-07-15 DK DK94923503T patent/DK0708768T3/da active
- 1994-07-15 CN CN94193161A patent/CN1050126C/zh not_active Expired - Fee Related
- 1994-07-15 WO PCT/US1994/007969 patent/WO1995002591A1/fr not_active Ceased
- 1994-07-15 AT AT94923503T patent/ATE236896T1/de not_active IP Right Cessation
- 1994-07-15 RU RU96103386/04A patent/RU2140918C1/ru not_active IP Right Cessation
- 1994-07-15 AT AT02079534T patent/ATE291576T1/de not_active IP Right Cessation
- 1994-07-15 FI FI960177A patent/FI960177A0/fi unknown
- 1994-07-15 SG SG1996003561A patent/SG52368A1/en unknown
- 1994-07-15 BR BR9407079A patent/BR9407079A/pt not_active Application Discontinuation
- 1994-07-15 SK SK47-96A patent/SK282342B6/sk unknown
- 1994-07-15 CZ CZ96119A patent/CZ11996A3/cs unknown
- 1994-07-15 ZA ZA945193A patent/ZA945193B/xx unknown
- 1994-07-15 AU AU73354/94A patent/AU694130C/en not_active Ceased
- 1994-07-15 PL PL94312614A patent/PL181705B1/pl unknown
- 1994-07-15 UA UA96010110A patent/UA63875C2/uk unknown
- 1994-10-04 TW TW083109192A patent/TW330934B/zh active
1996
- 1996-01-15 NO NO960173A patent/NO316881B1/no not_active IP Right Cessation
1997
- 1997-05-13 BR BR1100546-7A patent/BR1100546A/pt active IP Right Grant
1998
- 1998-05-04 IL IL12431898A patent/IL124318A0/xx unknown
- 1998-06-17 CN CN98115012A patent/CN1218801A/zh active Pending
- 1998-12-16 HK HK03100349.5A patent/HK1049658A1/en unknown
- 1998-12-16 HK HK03100345.9A patent/HK1049657A1/en unknown
- 1998-12-16 HK HK03100350.1A patent/HK1049659A1/en unknown
2001
- 2001-02-19 NO NO20010838A patent/NO20010838D0/no not_active Application Discontinuation
- 2001-02-19 NO NO20010837A patent/NO20010837D0/no not_active Application Discontinuation
- 2001-02-19 NO NO20010839A patent/NO20010839D0/no not_active Application Discontinuation
2003
- 2003-12-10 JP JP2003412024A patent/JP2004149541A/ja active Pending
- 2003-12-10 JP JP2003412029A patent/JP2004099622A/ja active Pending
- 2003-12-10 JP JP2003412020A patent/JP2004083600A/ja active Pending

Also Published As

Publication number	Publication date
AU694130B2 (en)	1998-07-16
DZ1798A1 (fr)	2002-02-17
EP0708768B1 (fr)	2003-04-09
DE69432463D1 (de)	2003-05-15
WO1995002591A1 (fr)	1995-01-26
NO10837A (no)	1996-01-15
EP1227091A2 (fr)	2002-07-31
CN1129447A (zh)	1996-08-21
TW330934B (en)	1998-05-01
NO20010837D0 (no)	2001-02-19
AP484A (en)	1996-04-23
ZA945193B (en)	1995-04-20
NO316881B1 (no)	2004-06-14
SI0708768T1 (en)	2003-10-31
AU705568B2 (en)	1999-05-27
DE69434316D1 (de)	2005-04-28
NO960173L (no)	1996-01-15
DE69432463T2 (de)	2004-02-12
JP2004083600A (ja)	2004-03-18
PL312614A1 (en)	1996-04-29
CZ11996A3 (en)	1996-10-16
FI960177L (fi)	1996-01-15
UA63875C2 (en)	2004-02-16
EP1227092A3 (fr)	2002-08-07
RU2140918C1 (ru)	1999-11-10
ES2237650T3 (es)	2005-08-01
NO20010839D0 (no)	2001-02-19
JPH09500137A (ja)	1997-01-07
NO20010838D0 (no)	2001-02-19
AU7185098A (en)	1998-08-27
SK282342B6 (sk)	2002-01-07
PL181705B1 (pl)	2001-09-28
NO10839A (no)	1996-01-15
NZ329994A (en)	1999-07-29
DK0708768T3 (da)	2003-08-04
HK1012392A1 (en)	1999-07-30
CA2167311A1 (fr)	1995-01-26
EP0708768A1 (fr)	1996-05-01
EP1227092A2 (fr)	2002-07-31
JP2004099622A (ja)	2004-04-02
SK4796A3 (en)	1997-01-08
PT708768E (pt)	2003-08-29
FI960177A7 (fi)	1996-01-15
AU694130C (en)	2002-12-05
EP1291346B1 (fr)	2005-03-23
AP9400654A0 (en)	1994-07-31
ATE291576T1 (de)	2005-04-15
NZ269457A (en)	1998-08-26
HK1049659A1 (en)	2003-05-23
IL110296A0 (en)	1994-10-21
NO960173D0 (no)	1996-01-15
FI960177A0 (fi)	1996-01-15
PL181723B1 (pl)	2001-09-28
HK1049658A1 (en)	2003-05-23
MY116478A (en)	2004-02-28
CN1218801A (zh)	1999-06-09
EP0708768A4 (fr)	1996-08-21
HUT75313A (en)	1997-05-28
MA23270A1 (fr)	1995-04-01
AU7335494A (en)	1995-02-13
PL181721B1 (en)	2001-09-28
HU9503855D0 (en)	1996-02-28
BR9407079A (pt)	1996-08-27
EP1291346A1 (fr)	2003-03-12
NO10838A (no)	1996-01-15
EP1229035A1 (fr)	2002-08-07
ES2197167T3 (es)	2004-01-01
BR1100546A (pt)	2004-08-31
PL181694B1 (pl)	2001-09-28
ATE236896T1 (de)	2003-04-15
SG52368A1 (en)	1998-09-28
CN1050126C (zh)	2000-03-08
DE69434316T2 (de)	2006-03-09
JP2004149541A (ja)	2004-05-27
EP1227091A3 (fr)	2002-08-07
HK1049657A1 (en)	2003-05-23
IL124318A0 (en)	1998-12-06

Legal Events

Date	Code	Title	Description
2000-06-29	FF	Patent granted
2005-07-25	MM9K	Patent not in force due to non-payment of renewal fees

Publication	Publication Date	Title
IL110296A (en)	1999-12-31	Imidazole compounds process for their preparation and pharmaceutical compositions containing them
IL116455A0 (en)	1996-03-31	Imidazole compounds and pharmaceutical compositions containing them
HUT64734A (en)	1994-02-28	Anthraquinone-derivativdes, process for preparing them and pharmaceutical compositions containing them
IL105220A0 (en)	1994-08-26	Cyclohexanylidene compounds and pharmaceutical compositions containing them
IL122618A0 (en)	1998-08-16	Substituted imidazolylacetonitrile compounds their preparation and pharmaceutical compositions containing them
HUT59677A (en)	1992-06-29	Process for producing indol- and benzimidazol-substituted imidazol deivatives and pharmaceutical compositions containing them
IL122717A0 (en)	1998-08-16	Compounds and pharmaceutical compositions containing them
ZA934090B (en)	1994-12-11	Biphenyl derivatives pharmaceutical compositions containing these compounds and processes for preparing them
HUT69712A (en)	1995-09-28	Process for preparing benzimidazole derivatives and pharmaceutical compositions containing them
ZA952046B (en)	1996-09-13	Benzimidazoles pharmaceutical compositions containing these compounds and processes for preparing them
IL115072A (en)	1999-12-31	Pharmaceutical compositions containing substituted 4-phenyl-6-amino-nicotinic acid derivatives their preparation some such new compounds and process for their preparation
IL117620A0 (en)	1996-07-23	Heterocyclic compounds processes for the preparation thereof and pharmaceutical compositions containing the same
SG43083A1 (en)	1997-10-17	Benzinidaziles pharmaceutical compositions containing these compounds and processes for preparing them
IL111011A0 (en)	1994-11-28	Bisbenzimidazole compounds, their preparation and pharmaceutical compositions containing them
HU9402187D0 (en)	1994-09-28	Heterocyclic compounds, process for producing them and pharmaceutical compositions containing them
ZA9511029B (en)	1997-06-30	Substituted 4-phenylthiazole derivatives process for their preparation and pharmaceutical compositions containing them
ZA945597B (en)	1996-01-29	Methyiguanidine derivatives process for their preparation and the compositions containing them
IL106385A0 (en)	1993-11-15	Heterocyclic compounds,their preparation and pharmaceutical compositions containing them
ZA941088B (en)	1995-09-27	Substituted ketophosphonates the processes for their preparation and pharmaceutical compositions containing them
HUT72319A (en)	1996-04-29	Epoxy-succinic acid derivatives, pharmaceutical compositions containing them and process for their preparation
HUP9601680A3 (en)	1998-08-28	Benzisothiazolyl-substituted aminomethyl-chromanes, pharmaceutical compositions containing the same, process for their preparation and use of the compounds
IL104471A0 (en)	1993-05-13	Imidazole derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
ZA966154B (en)	1997-01-23	Aminophenylphosphonic acid compounds process for preparing them and pharmaceutical compositions containing them
ZA963350B (en)	1996-11-04	Cycloheaxane compounds process for their preparation and pharmaceutical compositions containing them
ZA933638B (en)	1994-03-22	Heterocyclic compounds a process for the preparation thereof and pharmaceutical compositions containing them