IL111184A - Crystalline inclusion complex of diclofenac with unsubstituted beta-cyclodextrin - Google Patents

Crystalline inclusion complex of diclofenac with unsubstituted beta-cyclodextrin

Info

Publication number
IL111184A
IL111184A IL11118494A IL11118494A IL111184A IL 111184 A IL111184 A IL 111184A IL 11118494 A IL11118494 A IL 11118494A IL 11118494 A IL11118494 A IL 11118494A IL 111184 A IL111184 A IL 111184A
Authority
IL
Israel
Prior art keywords
diclofenac
cyclodextrin
inclusion complex
unsubstituted beta
crystalline inclusion
Prior art date
Application number
IL11118494A
Other languages
English (en)
Other versions
IL111184A0 (en
Original Assignee
Farmarc Nederland B V Of Cito
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmarc Nederland B V Of Cito filed Critical Farmarc Nederland B V Of Cito
Publication of IL111184A0 publication Critical patent/IL111184A0/xx
Publication of IL111184A publication Critical patent/IL111184A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nanotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL11118494A 1993-10-08 1994-10-06 Crystalline inclusion complex of diclofenac with unsubstituted beta-cyclodextrin IL111184A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ZA937480 1993-10-08

Publications (2)

Publication Number Publication Date
IL111184A0 IL111184A0 (en) 1994-12-29
IL111184A true IL111184A (en) 2000-08-13

Family

ID=66767030

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11118494A IL111184A (en) 1993-10-08 1994-10-06 Crystalline inclusion complex of diclofenac with unsubstituted beta-cyclodextrin

Country Status (12)

Country Link
US (1) US5674854A (de)
EP (1) EP0647451B1 (de)
JP (1) JPH07196484A (de)
KR (1) KR950010910A (de)
CN (1) CN1161115C (de)
AT (1) ATE294593T1 (de)
AU (1) AU682887B2 (de)
CA (1) CA2133885C (de)
DE (1) DE69434356T2 (de)
ES (1) ES2240960T3 (de)
IL (1) IL111184A (de)
ZA (1) ZA948078B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2735136B1 (fr) * 1995-06-08 1997-08-14 Roquette Freres Composition pulverulente d'hydroxypropyl-betacyclodextrine et son procede de preparation.
HUP9600758A2 (en) * 1996-03-27 1998-03-02 Cyclolab Ciklodextrin Kutato F Diclofenac composition of diminished gastrointestinal irritation and enhanced biological resorption
DE60004768T2 (de) * 1999-07-01 2004-07-08 Italfarmaco S.P.A. Komplexe von paroxetin mit cyclodextrin oder cyclodextrin derivaten
US7122376B2 (en) * 2001-11-01 2006-10-17 Facet Analytical Services And Technology, Llc Calibration standards, methods, and kits for water determination
US7049146B2 (en) 2000-11-14 2006-05-23 Facet Analytical Services And Technology, Llc Calibration standards, methods, and kits for water determination
JP2005298338A (ja) * 2002-02-27 2005-10-27 Eisai Co Ltd 速崩壊性圧縮成形製剤
KR100473716B1 (ko) * 2002-03-27 2005-03-08 주식회사 참 존 7-디하이드로콜레스테롤 및 사이클로덱스트린의 포접복합체, 이를 포함하는 화장료 조성물 및7-디하이드로콜레스테롤의 안정화방법
AU2003270727A1 (en) * 2002-09-17 2004-04-08 Luna Innovations, Inc. Remote temperature sensing of small volume and related apparatus thereof
FR2850040B1 (fr) * 2003-01-20 2005-03-11 Centre Nat Rech Scient Systemes pour microencapsulation et leurs applications
JP2007528384A (ja) * 2004-03-10 2007-10-11 シモダ、バイオテック(プロプライエタリー)リミテッド 安定な注射可能なジクロフェナク組成物
HUE058227T2 (hu) 2004-04-23 2022-07-28 Cydex Pharmaceuticals Inc DPI készítmény, amely szulfoalkil-éter-ciklodextrint tartalmaz
MX348982B (es) 2005-10-26 2017-07-06 Cydex Pharmaceuticals Inc Composiciones de eter sulfoalquilico-ciclodextrina y metodos de preparacion de las mismas.
US7629331B2 (en) * 2005-10-26 2009-12-08 Cydex Pharmaceuticals, Inc. Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof
US20070267033A1 (en) * 2006-02-09 2007-11-22 Philip Morris Usa Inc. Gamma cyclodextrin flavoring-release additives
KR20090010953A (ko) * 2006-03-28 2009-01-30 자블린 파머슈티칼스 인코포레이티드 저 복용량의 비-스테로이드성 항염증성 약물 및 베타-사이클로덱스트린 제형
MX2008012495A (es) 2006-03-28 2009-01-07 Javelin Pharmaceuticals Inc Formulaciones de dosis baja de diclofenaco y beta-ciclodextrina.
FR2912061A1 (fr) * 2007-02-01 2008-08-08 Aliscience Soc Par Actions Sim Complexes d'inclusion de cysteine, leur presparation et les compositions les contenant
WO2013013076A1 (en) * 2011-07-20 2013-01-24 Hospira, Inc. Methods of treating pain
CA3170465A1 (en) 2020-03-23 2021-09-30 Al Czap Oral terpene cyclodextrin inclusion complex vehicles
GB202105833D0 (en) * 2021-04-23 2021-06-09 Nacamed As Silicon particles for drug delivery

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5984821A (ja) * 1982-11-04 1984-05-16 Teikoku Chem Ind Corp Ltd 徐溶化組成物
IT1196033B (it) * 1984-02-22 1988-11-10 Chiesi Farma Spa Composto ad attivita' antiinfiammatoria ottenuto per complessazione con beta-ciclodestrina e relative formulazioni farmaceutiche
US4845188A (en) * 1988-08-19 1989-07-04 Eastman Kodak Company Condensation polymers containing methine ultraviolet radiation-absorbing residues and shaped articles produced therefrom
MY106598A (en) * 1988-08-31 1995-06-30 Australian Commercial Res & Development Ltd Compositions and methods for drug delivery and chromatography.
IT1241088B (it) * 1990-03-27 1993-12-29 Chiesi Farma Spa Procedimento per la preparazione di complessi piroxicam/ciclodestrina,prodotti ottenuti e loro composizioni farmaceutiche
IT1243342B (it) * 1990-07-13 1994-06-10 Farcon Ag Composizioni farmaceutiche orali liquide ad attivita' antiinfiammatoria
DE69231457T2 (de) * 1991-06-21 2001-05-23 Takeda Chemical Industries Ltd Zyklodextrin-Zusammensetzung enthaltend Fumagillol-Derivate
DE4200792A1 (de) * 1992-01-15 1993-07-22 Solvay Fluor & Derivate Aufarbeitung der fluorwasserstoff-phase aus reaktionsgemischen
JPH0616547A (ja) * 1992-07-01 1994-01-25 Wakamoto Pharmaceut Co Ltd 消炎点眼剤

Also Published As

Publication number Publication date
IL111184A0 (en) 1994-12-29
CN1107042A (zh) 1995-08-23
CA2133885C (en) 2008-12-16
AU682887B2 (en) 1997-10-23
CN1161115C (zh) 2004-08-11
EP0647451B1 (de) 2005-05-04
DE69434356T2 (de) 2006-05-04
ATE294593T1 (de) 2005-05-15
ZA948078B (en) 1995-06-05
CA2133885A1 (en) 1995-04-09
DE69434356D1 (de) 2005-06-09
EP0647451A1 (de) 1995-04-12
KR950010910A (ko) 1995-05-15
JPH07196484A (ja) 1995-08-01
ES2240960T3 (es) 2005-10-16
AU7448694A (en) 1995-04-27
US5674854A (en) 1997-10-07

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