IL113747A - Processes for preparing anhydrous forms of antihistaminic piperidine derivatives, polymorphs and psedomorphs thereof - Google Patents

Processes for preparing anhydrous forms of antihistaminic piperidine derivatives, polymorphs and psedomorphs thereof

Info

Publication number
IL113747A
IL113747A IL11374795A IL11374795A IL113747A IL 113747 A IL113747 A IL 113747A IL 11374795 A IL11374795 A IL 11374795A IL 11374795 A IL11374795 A IL 11374795A IL 113747 A IL113747 A IL 113747A
Authority
IL
Israel
Prior art keywords
water
compound
anhydrous
hydroxybutyl
formula
Prior art date
Application number
IL11374795A
Other languages
English (en)
Other versions
IL113747A0 (en
Original Assignee
Marion Merrell Dow Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26937420&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL113747(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Marion Merrell Dow Inc filed Critical Marion Merrell Dow Inc
Priority to IL13491795A priority Critical patent/IL134917A/en
Publication of IL113747A0 publication Critical patent/IL113747A0/xx
Priority to IL13491700A priority patent/IL134917A0/xx
Publication of IL113747A publication Critical patent/IL113747A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IL11374795A 1994-05-18 1995-05-16 Processes for preparing anhydrous forms of antihistaminic piperidine derivatives, polymorphs and psedomorphs thereof IL113747A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IL13491795A IL134917A (en) 1994-05-18 1995-05-16 Processes for preparing hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof
IL13491700A IL134917A0 (en) 1994-05-18 2000-03-07 Processes for preparing hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24573194A 1994-05-18 1994-05-18
US41716195A 1995-04-11 1995-04-11

Publications (2)

Publication Number Publication Date
IL113747A0 IL113747A0 (en) 1995-08-31
IL113747A true IL113747A (en) 2001-05-20

Family

ID=26937420

Family Applications (3)

Application Number Title Priority Date Filing Date
IL11374795A IL113747A (en) 1994-05-18 1995-05-16 Processes for preparing anhydrous forms of antihistaminic piperidine derivatives, polymorphs and psedomorphs thereof
IL13491795A IL134917A (en) 1994-05-18 1995-05-16 Processes for preparing hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof
IL13491700A IL134917A0 (en) 1994-05-18 2000-03-07 Processes for preparing hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL13491795A IL134917A (en) 1994-05-18 1995-05-16 Processes for preparing hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof
IL13491700A IL134917A0 (en) 1994-05-18 2000-03-07 Processes for preparing hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof

Country Status (17)

Country Link
US (12) US20010012896A1 (fr)
EP (3) EP1178041A1 (fr)
JP (7) JPH10500134A (fr)
CN (3) CN1148849A (fr)
AT (1) ATE220667T1 (fr)
AU (1) AU693892B2 (fr)
CA (3) CA2585705C (fr)
DE (1) DE69527429T2 (fr)
DK (1) DK0766668T3 (fr)
ES (1) ES2176329T3 (fr)
FI (1) FI964565A0 (fr)
HU (1) HU227676B1 (fr)
IL (3) IL113747A (fr)
MX (1) MX9605613A (fr)
NO (1) NO315319B1 (fr)
PT (1) PT766668E (fr)
WO (1) WO1995031437A1 (fr)

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GB9400555D0 (en) * 1994-01-13 1994-03-09 Short Brothers Plc Boundery layer control in aerodynamic low drag structures
CN1148849A (zh) 1994-05-18 1997-04-30 赫彻斯特马里恩鲁斯公司 抗组胺哌啶衍生物，其多晶形物和假同晶物的无水和水合物形式的制备方法
WO1996026726A1 (fr) * 1995-02-28 1996-09-06 Hoechst Marion Roussel, Inc. Composition pharmaceutique pour composes de piperidinoalcanol
CN1159012C (zh) * 1997-08-26 2004-07-28 阿旺蒂斯制药公司 用于组合哌啶子基烷醇-减充血剂的药物组合物
IN191492B (fr) * 1999-05-25 2003-12-06 Ranbaxy Lab Ltd
US6613906B1 (en) * 2000-06-06 2003-09-02 Geneva Pharmaceuticals, Inc. Crystal modification
CH695216A5 (de) * 2001-02-23 2006-01-31 Cilag Ag Verfahren zur Herstellung eines nicht hydratisierten Salzes eines Piperidinderivats und eine so erhältliche neue kristalline Form eines solchen Salzes.
CZ20033019A3 (cs) * 2001-04-09 2004-07-14 Teva Pharmaceutical Industries Ltd. Polymorfní formy chloridu fexofenadinu
US20030021849A1 (en) * 2001-04-09 2003-01-30 Ben-Zion Dolitzky Polymorphs of fexofenadine hydrochloride
BR0117054A (pt) * 2001-06-18 2004-07-27 Reddys Lab Ltd Dr Formas cristalinas do ácido 4-[4-[4-hidroxidifenilmetil)-1-piperidinil]-1-hidroxibuti l]-alfa, alfa-dimetilbenzeno acético e seu cloridrato
US7700779B2 (en) 2001-06-18 2010-04-20 Dr. Reddy's Laboratories Limited Crystalline forms of fexofenadine and its hydrochloride
WO2003011295A1 (fr) * 2001-07-31 2003-02-13 Texcontor Etablissement Agent polymorphe de fexofenadine
US20030158227A1 (en) * 2001-11-08 2003-08-21 Barnaba Krochmal Polymorphs of fexofenadine base
ES2239554T1 (es) 2002-06-10 2005-10-01 Teva Pharmaceutical Industries Ltd. Forma xvi polimorfica de hidrocloruro de fexofenadina.
JP3910907B2 (ja) * 2002-10-29 2007-04-25 新光電気工業株式会社 キャパシタ素子及びこの製造方法、半導体装置用基板、並びに半導体装置
EP1612212A1 (fr) * 2003-07-03 2006-01-04 Teva Pharmaceutical Industries Ltd Formes cristallines d'acide zoledronique et de ses sels de sodium, sel de sodium de preparation de ceux-ci
GB0319935D0 (en) * 2003-08-26 2003-09-24 Cipla Ltd Polymorphs
US20050256163A1 (en) * 2004-04-26 2005-11-17 Ilan Kor Crystalline forms of fexofenadine hydrochloride and processes for their preparation
ITMI20041143A1 (it) 2004-06-08 2004-09-08 Dipharma Spa Polimorfi di fexofenadina e procedimento per la loro preparazione
EP1616861A3 (fr) * 2004-06-15 2006-02-08 Dipharma S.p.A. Procédé de préparation de composés cétoniques
ITMI20041568A1 (it) * 2004-07-30 2004-10-30 Dipharma Spa "polimorfi di fexofenadina base"
JP2008514641A (ja) * 2004-09-28 2008-05-08 テバ ファーマシューティカル インダストリーズ リミティド 結晶形フェキソフェナジン、およびその調製方法
DOP2006000274A (es) * 2005-12-14 2007-10-15 Sanofi Aventis Us Llc Formulación de suspensión de fexofenadina
EP2046299A1 (fr) * 2006-07-11 2009-04-15 Mutual Pharmaceutical Company, Inc. Formulations à libération controlée
US20090076080A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched fexofenadine
EP2105134A1 (fr) 2008-03-24 2009-09-30 Ranbaxy Laboratories Limited Hydrochlorure de fexofenadine amorphe stable
US20100183717A1 (en) * 2009-01-16 2010-07-22 Kristin Arnold Controlled-release formulations
KR20120115492A (ko) 2009-11-06 2012-10-18 바스프 에스이 ４―히드록시 벤조산 및 선택된 살충제의 결정질 복합체
WO2011158262A1 (fr) 2010-06-15 2011-12-22 Chemelectiva S.R.L. Forme polymorphe du chlorhydrate de fexofénadine, intermédiaires et procédé de préparation
IT1400965B1 (it) * 2010-06-15 2013-07-05 Dipharma Francis Srl Polimorfi di fexofenadina
US9420872B2 (en) * 2010-08-23 2016-08-23 Jason Bird Apparatus and system for holding game-calling devices
JP2012087100A (ja) * 2010-10-21 2012-05-10 Sumitomo Chemical Co Ltd 形態ｉのフェキソフェナジン一塩酸塩の製造方法
CN104072402B (zh) * 2014-07-16 2016-08-17 昆山龙灯瑞迪制药有限公司 一种新结晶形式的盐酸非索非那定化合物及其制备方法

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IL134772A (en) 1995-02-28 2002-02-10 Aventis Pharma Inc Pharmaceutical compositions of piperidinoalkanol compounds in solid unit dosage form
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CN1159012C (zh) * 1997-08-26 2004-07-28 阿旺蒂斯制药公司 用于组合哌啶子基烷醇-减充血剂的药物组合物
US6214427B1 (en) * 1998-08-28 2001-04-10 General Electric Company Method of making an electronic device having a single crystal substrate formed by solid state crystal conversion
US6613906B1 (en) 2000-06-06 2003-09-02 Geneva Pharmaceuticals, Inc. Crystal modification
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US6475942B1 (en) * 2000-09-05 2002-11-05 General Electric Company Conversion of polycrystalline alumina to single crystal sapphire using molybdenum doping
CZ20033019A3 (cs) * 2001-04-09 2004-07-14 Teva Pharmaceutical Industries Ltd. Polymorfní formy chloridu fexofenadinu
US7700779B2 (en) * 2001-06-18 2010-04-20 Dr. Reddy's Laboratories Limited Crystalline forms of fexofenadine and its hydrochloride
US20090211514A1 (en) * 2008-02-26 2009-08-27 Lehigh University Single crystal conversion process

Also Published As

Publication number Publication date
IL134917A (en) 2001-07-24
NO964859L (no) 1996-11-15
US20020193600A1 (en) 2002-12-19
JP4503908B2 (ja) 2010-07-14
EP0766668A1 (fr) 1997-04-09
US7662835B2 (en) 2010-02-16
JP2002308850A (ja) 2002-10-23
JP2002255936A (ja) 2002-09-11
CA2449419A1 (fr) 1995-11-23
PT766668E (pt) 2002-11-29
MX9605613A (es) 1998-05-31
IL134917A0 (en) 2001-05-20
DE69527429D1 (de) 2002-08-22
EP1178041A1 (fr) 2002-02-06
WO1995031437A1 (fr) 1995-11-23
US20010025106A1 (en) 2001-09-27
JP4503909B2 (ja) 2010-07-14
NO315319B1 (no) 2003-08-18
US20040014976A1 (en) 2004-01-22
JPH10500134A (ja) 1998-01-06
CA2585705A1 (fr) 1995-11-23
US20010012896A1 (en) 2001-08-09
FI964565A7 (fi) 1996-11-14
CA2449419C (fr) 2011-09-06
JP2010120969A (ja) 2010-06-03
EP0766668B1 (fr) 2002-07-17
HU9603167D0 (en) 1997-01-28
CN1907967B (zh) 2012-07-04
US20070021461A1 (en) 2007-01-25
FI964565L (fi) 1996-11-14
EP2354125A1 (fr) 2011-08-10
JP2002308849A (ja) 2002-10-23
JP2002255935A (ja) 2002-09-11
CA2585705C (fr) 2012-04-17
CN1623985A (zh) 2005-06-08
US20010014741A1 (en) 2001-08-16
NO964859D0 (no) 1996-11-15
DE69527429T2 (de) 2003-03-20
JP2002316978A (ja) 2002-10-31
US20020193603A1 (en) 2002-12-19
HU227676B1 (en) 2011-11-28
IL113747A0 (en) 1995-08-31
US20080167471A1 (en) 2008-07-10
CA2189007C (fr) 2004-03-02
AU693892B2 (en) 1998-07-09
US7135571B2 (en) 2006-11-14
AU2426595A (en) 1995-12-05
HK1098467A1 (en) 2007-07-20
CN1907967A (zh) 2007-02-07
US20080167469A1 (en) 2008-07-10
US7138524B2 (en) 2006-11-21
JP4503907B2 (ja) 2010-07-14
ES2176329T3 (es) 2002-12-01
US20070021462A1 (en) 2007-01-25
US20020193601A1 (en) 2002-12-19
HUT76134A (en) 1997-06-30
DK0766668T3 (da) 2002-10-28
CA2189007A1 (fr) 1995-11-23
FI964565A0 (fi) 1996-11-14
ATE220667T1 (de) 2002-08-15
CN1148849A (zh) 1997-04-30
US7666881B2 (en) 2010-02-23
US20030045721A1 (en) 2003-03-06
HK1137742A1 (en) 2010-08-06

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