IL114877A - Derivatives of benzothiazepines pharmaceutical compositions containing them and their use - Google Patents

Derivatives of benzothiazepines pharmaceutical compositions containing them and their use

Info

Publication number
IL114877A
IL114877A IL11487795A IL11487795A IL114877A IL 114877 A IL114877 A IL 114877A IL 11487795 A IL11487795 A IL 11487795A IL 11487795 A IL11487795 A IL 11487795A IL 114877 A IL114877 A IL 114877A
Authority
IL
Israel
Prior art keywords
benzothiazepines
derivatives
pharmaceutical compositions
compositions containing
pharmaceutical
Prior art date
Application number
IL11487795A
Other languages
English (en)
Other versions
IL114877A0 (en
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of IL114877A0 publication Critical patent/IL114877A0/xx
Publication of IL114877A publication Critical patent/IL114877A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6536—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
IL11487795A 1994-08-10 1995-08-09 Derivatives of benzothiazepines pharmaceutical compositions containing them and their use IL114877A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28852794A 1994-08-10 1994-08-10

Publications (2)

Publication Number Publication Date
IL114877A0 IL114877A0 (en) 1995-12-08
IL114877A true IL114877A (en) 1999-07-14

Family

ID=23107516

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11487795A IL114877A (en) 1994-08-10 1995-08-09 Derivatives of benzothiazepines pharmaceutical compositions containing them and their use

Country Status (30)

Country Link
US (1) US5910494A (de)
EP (2) EP0775126B1 (de)
JP (1) JP2935756B2 (de)
KR (1) KR100354288B1 (de)
CN (1) CN1059673C (de)
AP (1) AP720A (de)
AT (1) ATE226946T1 (de)
AU (1) AU696073B2 (de)
BG (1) BG62048B1 (de)
BR (1) BR9508586A (de)
CA (1) CA2197099A1 (de)
CZ (1) CZ37397A3 (de)
DE (1) DE69528704T2 (de)
DK (1) DK0775126T3 (de)
EE (1) EE9700028A (de)
ES (1) ES2185711T3 (de)
FI (1) FI970531A0 (de)
HU (1) HUT77129A (de)
IL (1) IL114877A (de)
IS (1) IS4418A (de)
MX (1) MX9700890A (de)
NO (1) NO308131B1 (de)
NZ (1) NZ290911A (de)
OA (1) OA10597A (de)
PL (1) PL184512B1 (de)
PT (1) PT775126E (de)
RU (1) RU2156245C2 (de)
SK (1) SK17797A3 (de)
WO (1) WO1996005188A1 (de)
ZA (1) ZA956647B (de)

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US6107494A (en) * 1994-09-13 2000-08-22 G.D. Searle And Company Substituted 5-aryl-benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
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GB9800428D0 (en) 1998-01-10 1998-03-04 Glaxo Group Ltd Chemical compounds
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JP2002533412A (ja) 1998-12-23 2002-10-08 ジー．ディー．サール エルエルシー 心臓血管に適用するための回腸胆汁酸輸送阻害剤およびコレステリルエステル転送タンパク質阻害剤の組み合わせ
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Also Published As

Publication number Publication date
EP0775126A1 (de) 1997-05-28
BG101209A (bg) 1997-08-29
NO970585D0 (no) 1997-02-07
EE9700028A (et) 1997-08-15
CA2197099A1 (en) 1996-02-22
HK1003936A1 (en) 1998-11-13
PT775126E (pt) 2003-02-28
DE69528704T2 (de) 2003-06-12
CN1059673C (zh) 2000-12-20
SK17797A3 (en) 1997-09-10
US5910494A (en) 1999-06-08
FI970531L (fi) 1997-02-07
WO1996005188A1 (en) 1996-02-22
KR100354288B1 (ko) 2003-01-06
RU2156245C2 (ru) 2000-09-20
AP9700920A0 (en) 1997-01-31
DK0775126T3 (da) 2003-03-03
AP720A (en) 1999-01-08
MX9700890A (es) 1997-04-30
BG62048B1 (bg) 1999-01-29
PL184512B1 (pl) 2002-11-29
JPH10504035A (ja) 1998-04-14
EP0775126B1 (de) 2002-10-30
DE69528704D1 (de) 2002-12-05
CZ37397A3 (en) 1997-08-13
AU696073B2 (en) 1998-09-03
NO970585L (no) 1997-04-07
NZ290911A (en) 1998-07-28
ZA956647B (en) 1997-02-10
IS4418A (is) 1997-01-24
FI970531A7 (fi) 1997-02-07
BR9508586A (pt) 1998-07-14
EP1203769A1 (de) 2002-05-08
FI970531A0 (fi) 1997-02-07
IL114877A0 (en) 1995-12-08
JP2935756B2 (ja) 1999-08-16
NO308131B1 (no) 2000-07-31
ES2185711T3 (es) 2003-05-01
HUT77129A (hu) 1998-03-02
ATE226946T1 (de) 2002-11-15
CN1161035A (zh) 1997-10-01
PL318496A1 (en) 1997-06-23
AU4426096A (en) 1996-03-07
OA10597A (en) 2002-08-22

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