SK17797A3 - 1,4-benzothiazepine-1,1-dioxides, process for producing them and a pharmaceutical composition containing them - Google Patents

1,4-benzothiazepine-1,1-dioxides, process for producing them and a pharmaceutical composition containing them Download PDF

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Publication number
SK17797A3
SK17797A3 SK177-97A SK17797A SK17797A3 SK 17797 A3 SK17797 A3 SK 17797A3 SK 17797 A SK17797 A SK 17797A SK 17797 A3 SK17797 A3 SK 17797A3
Authority
SK
Slovakia
Prior art keywords
phenyl
tetrahydro
dioxide
ethyl
butyl
Prior art date
Application number
SK177-97A
Other languages
English (en)
Slovak (sk)
Inventor
Lawrence Edward Brieaddy
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of SK17797A3 publication Critical patent/SK17797A3/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6536—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and sulfur atoms with or without oxygen atoms, as the only ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
SK177-97A 1994-08-10 1995-08-09 1,4-benzothiazepine-1,1-dioxides, process for producing them and a pharmaceutical composition containing them SK17797A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28852794A 1994-08-10 1994-08-10
PCT/GB1995/001884 WO1996005188A1 (en) 1994-08-10 1995-08-09 Hypolipidemic 1,4-benzothiazepine-1,1-dioxides

Publications (1)

Publication Number Publication Date
SK17797A3 true SK17797A3 (en) 1997-09-10

Family

ID=23107516

Family Applications (1)

Application Number Title Priority Date Filing Date
SK177-97A SK17797A3 (en) 1994-08-10 1995-08-09 1,4-benzothiazepine-1,1-dioxides, process for producing them and a pharmaceutical composition containing them

Country Status (30)

Country Link
US (1) US5910494A (de)
EP (2) EP1203769A1 (de)
JP (1) JP2935756B2 (de)
KR (1) KR100354288B1 (de)
CN (1) CN1059673C (de)
AP (1) AP720A (de)
AT (1) ATE226946T1 (de)
AU (1) AU696073B2 (de)
BG (1) BG62048B1 (de)
BR (1) BR9508586A (de)
CA (1) CA2197099A1 (de)
CZ (1) CZ37397A3 (de)
DE (1) DE69528704T2 (de)
DK (1) DK0775126T3 (de)
EE (1) EE9700028A (de)
ES (1) ES2185711T3 (de)
FI (1) FI970531A7 (de)
HU (1) HUT77129A (de)
IL (1) IL114877A (de)
IS (1) IS4418A (de)
MX (1) MX9700890A (de)
NO (1) NO308131B1 (de)
NZ (1) NZ290911A (de)
OA (1) OA10597A (de)
PL (1) PL184512B1 (de)
PT (1) PT775126E (de)
RU (1) RU2156245C2 (de)
SK (1) SK17797A3 (de)
WO (1) WO1996005188A1 (de)
ZA (1) ZA956647B (de)

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IL108634A0 (en) * 1993-02-15 1994-05-30 Wellcome Found Hypolipidaemic heterocyclic compounds, their prepatation and pharmaceutical compositions containing them
IL108633A (en) * 1993-02-15 1998-07-15 Wellcome Found History of Benzothiazepine Hypolipidemic Preparation and Pharmaceutical Preparations Containing Them
BR9508916A (pt) * 1994-09-13 1997-12-30 Monsanto Co "Novas benzotiepinas tendo atividade como inibidores de transporte do ácido biliar ileal e absorção de taurocolato"
GB9423172D0 (en) * 1994-11-17 1995-01-04 Wellcom Foundation The Limited Hypolipidemic benzothiazepines

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AP720A (en) 1999-01-08
BG101209A (bg) 1997-08-29
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JPH10504035A (ja) 1998-04-14
HK1003936A1 (en) 1998-11-13
JP2935756B2 (ja) 1999-08-16
EP1203769A1 (de) 2002-05-08
DE69528704D1 (de) 2002-12-05
HUT77129A (hu) 1998-03-02
NZ290911A (en) 1998-07-28
FI970531A0 (fi) 1997-02-07
EP0775126A1 (de) 1997-05-28
AU4426096A (en) 1996-03-07
ATE226946T1 (de) 2002-11-15
EE9700028A (et) 1997-08-15
IL114877A (en) 1999-07-14
US5910494A (en) 1999-06-08
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CA2197099A1 (en) 1996-02-22
CN1059673C (zh) 2000-12-20
NO970585L (no) 1997-04-07
IL114877A0 (en) 1995-12-08
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ZA956647B (en) 1997-02-10
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