IL115641A0 - Quinoxalines a process for their preparation and their use - Google Patents
Quinoxalines a process for their preparation and their useInfo
- Publication number
- IL115641A0 IL115641A0 IL11564195A IL11564195A IL115641A0 IL 115641 A0 IL115641 A0 IL 115641A0 IL 11564195 A IL11564195 A IL 11564195A IL 11564195 A IL11564195 A IL 11564195A IL 115641 A0 IL115641 A0 IL 115641A0
- Authority
- IL
- Israel
- Prior art keywords
- alkoxy
- quinoxalines
- preparation
- formula
- carbonyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Compounds Of Unknown Constitution (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Dental Preparations (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4437406A DE4437406A1 (de) | 1994-10-19 | 1994-10-19 | Chinoxaline, Verfahren zu ihrer Herstellung und ihre Verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL115641A0 true IL115641A0 (en) | 1996-01-19 |
Family
ID=6531202
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11564195A IL115641A0 (en) | 1994-10-19 | 1995-10-15 | Quinoxalines a process for their preparation and their use |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US5723461A (pt) |
| EP (1) | EP0708093B1 (pt) |
| JP (1) | JPH08225544A (pt) |
| KR (1) | KR960014108A (pt) |
| CN (1) | CN1094930C (pt) |
| AT (1) | ATE198747T1 (pt) |
| AU (1) | AU708293B2 (pt) |
| BR (1) | BR9504456A (pt) |
| CA (1) | CA2160859A1 (pt) |
| CZ (1) | CZ271295A3 (pt) |
| DE (2) | DE4437406A1 (pt) |
| DK (1) | DK0708093T3 (pt) |
| ES (1) | ES2154311T3 (pt) |
| FI (1) | FI954946A7 (pt) |
| GR (1) | GR3035673T3 (pt) |
| HR (1) | HRP950524B1 (pt) |
| HU (1) | HUT73485A (pt) |
| IL (1) | IL115641A0 (pt) |
| MY (1) | MY132057A (pt) |
| NO (1) | NO306615B1 (pt) |
| NZ (1) | NZ280258A (pt) |
| PL (1) | PL184860B1 (pt) |
| PT (1) | PT708093E (pt) |
| SI (1) | SI9500329A (pt) |
| SK (1) | SK128495A3 (pt) |
| TW (1) | TW328954B (pt) |
| ZA (1) | ZA958783B (pt) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6369057B1 (en) * | 1991-04-15 | 2002-04-09 | Aventis Pharma Deutschland Gmbh | Quinoxalines, processes for their preparation and their use |
| US6015800A (en) * | 1997-09-03 | 2000-01-18 | Warner-Lambert Company | Substituted quinoxaline-2-ones as glutamate receptor antagonists |
| WO1999025327A2 (en) * | 1997-11-14 | 1999-05-27 | Warner-Lambert Company | Small molecule intervention in hiv-1 replication |
| GB9901795D0 (en) * | 1999-01-28 | 1999-03-17 | Glaxo Group Ltd | Chemical compounds |
| GB9911887D0 (en) * | 1999-05-21 | 1999-07-21 | Glaxo Group Ltd | Methods and medicaments for post exposure prophylaxis of an hiv infection |
| WO2002087500A2 (en) * | 2001-04-27 | 2002-11-07 | Newbiotics, Inc. | Viral enzyme activated prototoxophores and use of same to treat viral infections |
| WO2005018531A2 (en) * | 2003-08-26 | 2005-03-03 | 'chemical Diversity Research Institute', Ltd. | Pharmaceutical compositions, azo-heterocyclic compounds and method for the production and use thereof |
| US7351709B2 (en) * | 2004-06-09 | 2008-04-01 | Wyeth | Estrogen receptor ligands |
| MX371331B (es) | 2012-04-24 | 2020-01-27 | Vertex Pharma | Inhibidores de la proteina cinasa dependiente de acido desoxirribonucleico(adn-pk). |
| ME03336B (me) | 2013-03-12 | 2019-10-20 | Vertex Pharma | Inhibitori dnk-pk |
| JP6408569B2 (ja) | 2013-10-17 | 2018-10-17 | バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated | Dna−pk阻害剤としての(s)−n−メチル−8−(1−((2’−メチル−[4,5’−ビピリミジン]−6−イル)アミノ)プロパン−2−イル)キノリン−4−カルボキサミドおよびその重水素化誘導体の共結晶 |
| EP3518931A4 (en) | 2016-09-27 | 2020-05-13 | Vertex Pharmaceuticals Incorporated | METHOD FOR TREATING CANCER WITH A COMBINATION OF DNA-DAMAGING SUBSTANCES AND DNA-PK INHIBITORS |
| AU2022303386A1 (en) * | 2021-07-02 | 2023-12-14 | Aldeyra Therapeutics, Inc. | Heterocyclic aldehyde trapping compounds and uses thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE205837T1 (de) * | 1991-04-15 | 2001-10-15 | Aventis Pharma Gmbh | Chinoxaline, verfahren zu ihrer herstellung und ihre verwendung |
| DE4342024A1 (de) * | 1993-12-09 | 1995-06-14 | Hoechst Ag | Kombinationspräparate, enthaltend ein Chinoxalin und ein Nukleosid |
-
1994
- 1994-10-19 DE DE4437406A patent/DE4437406A1/de not_active Withdrawn
-
1995
- 1995-10-12 EP EP95116094A patent/EP0708093B1/de not_active Expired - Lifetime
- 1995-10-12 AT AT95116094T patent/ATE198747T1/de not_active IP Right Cessation
- 1995-10-12 DK DK95116094T patent/DK0708093T3/da active
- 1995-10-12 DE DE59508969T patent/DE59508969D1/de not_active Expired - Fee Related
- 1995-10-12 ES ES95116094T patent/ES2154311T3/es not_active Expired - Lifetime
- 1995-10-12 PT PT95116094T patent/PT708093E/pt unknown
- 1995-10-15 IL IL11564195A patent/IL115641A0/xx unknown
- 1995-10-16 TW TW084110841A patent/TW328954B/zh active
- 1995-10-17 AU AU34316/95A patent/AU708293B2/en not_active Ceased
- 1995-10-17 US US08/544,290 patent/US5723461A/en not_active Expired - Fee Related
- 1995-10-17 MY MYPI95003112A patent/MY132057A/en unknown
- 1995-10-17 FI FI954946A patent/FI954946A7/fi unknown
- 1995-10-17 CZ CZ952712A patent/CZ271295A3/cs unknown
- 1995-10-17 NZ NZ280258A patent/NZ280258A/en unknown
- 1995-10-17 SK SK1284-95A patent/SK128495A3/sk unknown
- 1995-10-18 CN CN95120372A patent/CN1094930C/zh not_active Expired - Fee Related
- 1995-10-18 NO NO954139A patent/NO306615B1/no not_active IP Right Cessation
- 1995-10-18 HU HU9503005A patent/HUT73485A/hu unknown
- 1995-10-18 CA CA002160859A patent/CA2160859A1/en not_active Abandoned
- 1995-10-18 ZA ZA958783A patent/ZA958783B/xx unknown
- 1995-10-18 KR KR1019950035876A patent/KR960014108A/ko not_active Abandoned
- 1995-10-18 PL PL95311016A patent/PL184860B1/pl unknown
- 1995-10-18 HR HR950524A patent/HRP950524B1/xx not_active IP Right Cessation
- 1995-10-19 JP JP7271019A patent/JPH08225544A/ja active Pending
- 1995-10-19 BR BR9504456A patent/BR9504456A/pt not_active IP Right Cessation
- 1995-10-19 SI SI9500329A patent/SI9500329A/sl unknown
-
2001
- 2001-03-30 GR GR20010400523T patent/GR3035673T3/el not_active IP Right Cessation
Also Published As
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