IL115641A0 - Quinoxalines a process for their preparation and their use - Google Patents

Quinoxalines a process for their preparation and their use

Info

Publication number
IL115641A0
IL115641A0 IL11564195A IL11564195A IL115641A0 IL 115641 A0 IL115641 A0 IL 115641A0 IL 11564195 A IL11564195 A IL 11564195A IL 11564195 A IL11564195 A IL 11564195A IL 115641 A0 IL115641 A0 IL 115641A0
Authority
IL
Israel
Prior art keywords
alkoxy
quinoxalines
preparation
formula
carbonyl
Prior art date
Application number
IL11564195A
Other languages
English (en)
Inventor
Manfred Dr Roesner
Uta-Maria Billhardt-Troughton
Reinhard Dr Kirsch
Joerg-Peter Dr Kleim
Christoph Dr Meichsner
Guenther Dr Ries
Irvin Dr Winkler
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IL115641A0 publication Critical patent/IL115641A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40Benzopyrazines
    • C07D241/44Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Dental Preparations (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL11564195A 1994-10-19 1995-10-15 Quinoxalines a process for their preparation and their use IL115641A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4437406A DE4437406A1 (de) 1994-10-19 1994-10-19 Chinoxaline, Verfahren zu ihrer Herstellung und ihre Verwendung

Publications (1)

Publication Number Publication Date
IL115641A0 true IL115641A0 (en) 1996-01-19

Family

ID=6531202

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11564195A IL115641A0 (en) 1994-10-19 1995-10-15 Quinoxalines a process for their preparation and their use

Country Status (27)

Country Link
US (1) US5723461A (pt)
EP (1) EP0708093B1 (pt)
JP (1) JPH08225544A (pt)
KR (1) KR960014108A (pt)
CN (1) CN1094930C (pt)
AT (1) ATE198747T1 (pt)
AU (1) AU708293B2 (pt)
BR (1) BR9504456A (pt)
CA (1) CA2160859A1 (pt)
CZ (1) CZ271295A3 (pt)
DE (2) DE4437406A1 (pt)
DK (1) DK0708093T3 (pt)
ES (1) ES2154311T3 (pt)
FI (1) FI954946A7 (pt)
GR (1) GR3035673T3 (pt)
HR (1) HRP950524B1 (pt)
HU (1) HUT73485A (pt)
IL (1) IL115641A0 (pt)
MY (1) MY132057A (pt)
NO (1) NO306615B1 (pt)
NZ (1) NZ280258A (pt)
PL (1) PL184860B1 (pt)
PT (1) PT708093E (pt)
SI (1) SI9500329A (pt)
SK (1) SK128495A3 (pt)
TW (1) TW328954B (pt)
ZA (1) ZA958783B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6369057B1 (en) * 1991-04-15 2002-04-09 Aventis Pharma Deutschland Gmbh Quinoxalines, processes for their preparation and their use
US6015800A (en) * 1997-09-03 2000-01-18 Warner-Lambert Company Substituted quinoxaline-2-ones as glutamate receptor antagonists
WO1999025327A2 (en) * 1997-11-14 1999-05-27 Warner-Lambert Company Small molecule intervention in hiv-1 replication
GB9901795D0 (en) * 1999-01-28 1999-03-17 Glaxo Group Ltd Chemical compounds
GB9911887D0 (en) * 1999-05-21 1999-07-21 Glaxo Group Ltd Methods and medicaments for post exposure prophylaxis of an hiv infection
WO2002087500A2 (en) * 2001-04-27 2002-11-07 Newbiotics, Inc. Viral enzyme activated prototoxophores and use of same to treat viral infections
WO2005018531A2 (en) * 2003-08-26 2005-03-03 'chemical Diversity Research Institute', Ltd. Pharmaceutical compositions, azo-heterocyclic compounds and method for the production and use thereof
US7351709B2 (en) * 2004-06-09 2008-04-01 Wyeth Estrogen receptor ligands
MX371331B (es) 2012-04-24 2020-01-27 Vertex Pharma Inhibidores de la proteina cinasa dependiente de acido desoxirribonucleico(adn-pk).
ME03336B (me) 2013-03-12 2019-10-20 Vertex Pharma Inhibitori dnk-pk
JP6408569B2 (ja) 2013-10-17 2018-10-17 バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated Dna−pk阻害剤としての(s)−n−メチル−8−(1−((2’−メチル−[4,5’−ビピリミジン]−6−イル)アミノ)プロパン−2−イル)キノリン−4−カルボキサミドおよびその重水素化誘導体の共結晶
EP3518931A4 (en) 2016-09-27 2020-05-13 Vertex Pharmaceuticals Incorporated METHOD FOR TREATING CANCER WITH A COMBINATION OF DNA-DAMAGING SUBSTANCES AND DNA-PK INHIBITORS
AU2022303386A1 (en) * 2021-07-02 2023-12-14 Aldeyra Therapeutics, Inc. Heterocyclic aldehyde trapping compounds and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE205837T1 (de) * 1991-04-15 2001-10-15 Aventis Pharma Gmbh Chinoxaline, verfahren zu ihrer herstellung und ihre verwendung
DE4342024A1 (de) * 1993-12-09 1995-06-14 Hoechst Ag Kombinationspräparate, enthaltend ein Chinoxalin und ein Nukleosid

Also Published As

Publication number Publication date
AU3431695A (en) 1996-05-02
BR9504456A (pt) 1997-05-20
NO954139L (no) 1996-04-22
FI954946L (fi) 1996-04-20
HRP950524B1 (en) 2002-06-30
JPH08225544A (ja) 1996-09-03
DE4437406A1 (de) 1996-04-25
SI9500329A (en) 1996-04-30
CZ271295A3 (en) 1996-08-14
EP0708093A1 (de) 1996-04-24
NO306615B1 (no) 1999-11-29
PT708093E (pt) 2001-06-29
FI954946A7 (fi) 1996-04-20
ATE198747T1 (de) 2001-02-15
SK128495A3 (en) 1996-06-05
MY132057A (en) 2007-09-28
GR3035673T3 (en) 2001-06-29
HK1011988A1 (en) 1999-07-23
DE59508969D1 (de) 2001-02-22
EP0708093B1 (de) 2001-01-17
AU708293B2 (en) 1999-07-29
NZ280258A (en) 1997-09-22
ZA958783B (en) 1996-05-09
CN1094930C (zh) 2002-11-27
FI954946A0 (fi) 1995-10-17
HU9503005D0 (en) 1995-12-28
PL184860B1 (pl) 2003-01-31
NO954139D0 (no) 1995-10-18
HRP950524A2 (en) 1997-10-31
CA2160859A1 (en) 1996-04-20
DK0708093T3 (da) 2001-04-30
TW328954B (en) 1998-04-01
US5723461A (en) 1998-03-03
ES2154311T3 (es) 2001-04-01
KR960014108A (ko) 1996-05-22
CN1135483A (zh) 1996-11-13
HUT73485A (en) 1996-08-28
PL311016A1 (en) 1996-04-29

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