TW328954B - Quinoxalines, a process for their preparation, and their use - Google Patents

Quinoxalines, a process for their preparation, and their use

Info

Publication number
TW328954B
TW328954B TW084110841A TW84110841A TW328954B TW 328954 B TW328954 B TW 328954B TW 084110841 A TW084110841 A TW 084110841A TW 84110841 A TW84110841 A TW 84110841A TW 328954 B TW328954 B TW 328954B
Authority
TW
Taiwan
Prior art keywords
quinoxalines
preparation
alkoxy
hydroxy
alkenoxycarbonyl
Prior art date
Application number
TW084110841A
Other languages
English (en)
Inventor
Rosner Manfred
Billhardt-Troughton Uta-Maria
Kirsch Reinhard
Kleim Jorg-Peter
Meichsner Christoph
Rieb Gunther
Winkler Irvin
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Application granted granted Critical
Publication of TW328954B publication Critical patent/TW328954B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40—Benzopyrazines
    • C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Dental Preparations (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
TW084110841A 1994-10-19 1995-10-16 Quinoxalines, a process for their preparation, and their use TW328954B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4437406A DE4437406A1 (de) 1994-10-19 1994-10-19 Chinoxaline, Verfahren zu ihrer Herstellung und ihre Verwendung

Publications (1)

Publication Number Publication Date
TW328954B true TW328954B (en) 1998-04-01

Family

ID=6531202

Family Applications (1)

Application Number Title Priority Date Filing Date
TW084110841A TW328954B (en) 1994-10-19 1995-10-16 Quinoxalines, a process for their preparation, and their use

Country Status (27)

Country Link
US (1) US5723461A (zh)
EP (1) EP0708093B1 (zh)
JP (1) JPH08225544A (zh)
KR (1) KR960014108A (zh)
CN (1) CN1094930C (zh)
AT (1) ATE198747T1 (zh)
AU (1) AU708293B2 (zh)
BR (1) BR9504456A (zh)
CA (1) CA2160859A1 (zh)
CZ (1) CZ271295A3 (zh)
DE (2) DE4437406A1 (zh)
DK (1) DK0708093T3 (zh)
ES (1) ES2154311T3 (zh)
FI (1) FI954946A7 (zh)
GR (1) GR3035673T3 (zh)
HR (1) HRP950524B1 (zh)
HU (1) HUT73485A (zh)
IL (1) IL115641A0 (zh)
MY (1) MY132057A (zh)
NO (1) NO306615B1 (zh)
NZ (1) NZ280258A (zh)
PL (1) PL184860B1 (zh)
PT (1) PT708093E (zh)
SI (1) SI9500329A (zh)
SK (1) SK128495A3 (zh)
TW (1) TW328954B (zh)
ZA (1) ZA958783B (zh)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6369057B1 (en) * 1991-04-15 2002-04-09 Aventis Pharma Deutschland Gmbh Quinoxalines, processes for their preparation and their use
US6015800A (en) * 1997-09-03 2000-01-18 Warner-Lambert Company Substituted quinoxaline-2-ones as glutamate receptor antagonists
WO1999025327A2 (en) * 1997-11-14 1999-05-27 Warner-Lambert Company Small molecule intervention in hiv-1 replication
GB9901795D0 (en) * 1999-01-28 1999-03-17 Glaxo Group Ltd Chemical compounds
GB9911887D0 (en) * 1999-05-21 1999-07-21 Glaxo Group Ltd Methods and medicaments for post exposure prophylaxis of an hiv infection
WO2002087500A2 (en) * 2001-04-27 2002-11-07 Newbiotics, Inc. Viral enzyme activated prototoxophores and use of same to treat viral infections
WO2005018531A2 (en) * 2003-08-26 2005-03-03 'chemical Diversity Research Institute', Ltd. Pharmaceutical compositions, azo-heterocyclic compounds and method for the production and use thereof
US7351709B2 (en) * 2004-06-09 2008-04-01 Wyeth Estrogen receptor ligands
SI3459942T1 (sl) 2012-04-24 2021-05-31 Vertex Pharmaceuticals Incorporated Inhibitorji DNA-PK
HUE041544T2 (hu) 2013-03-12 2019-05-28 Vertex Pharma DNS-PK inhibitorok
PT3424920T (pt) 2013-10-17 2020-07-07 Vertex Pharma Co-cristais de (s)-n-metil-8-(1-((2'-metil-[4,5'-bipirimidin]-6-il)amino)propan-2-il)quinolina-4-carboxamida e derivados deuterados dos mesmos como inibidores de adn-pk
JP2019529475A (ja) 2016-09-27 2019-10-17 バーテックス ファーマシューティカルズ インコーポレイテッドＶｅｒｔｅｘ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃｏｒｐｏｒａｔｅｄ Ｄｎａ損傷剤とｄｎａ−ｐｋ阻害剤との組合せ物を使用する、がんを処置するための方法
CN117580569A (zh) * 2021-07-02 2024-02-20 奥尔德拉医疗公司 杂环型醛捕获化合物和其用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT509398E (pt) * 1991-04-15 2002-02-28 Aventis Pharma Gmbh Quinoxalinas processo para a sua preparacao e sua utilizacao
DE4342024A1 (de) * 1993-12-09 1995-06-14 Hoechst Ag Kombinationspräparate, enthaltend ein Chinoxalin und ein Nukleosid

Also Published As

Publication number Publication date
CZ271295A3 (en) 1996-08-14
NO306615B1 (no) 1999-11-29
PT708093E (pt) 2001-06-29
SI9500329A (en) 1996-04-30
CN1094930C (zh) 2002-11-27
MY132057A (en) 2007-09-28
GR3035673T3 (en) 2001-06-29
CA2160859A1 (en) 1996-04-20
PL184860B1 (pl) 2003-01-31
AU708293B2 (en) 1999-07-29
HRP950524B1 (en) 2002-06-30
IL115641A0 (en) 1996-01-19
PL311016A1 (en) 1996-04-29
JPH08225544A (ja) 1996-09-03
FI954946L (fi) 1996-04-20
NO954139L (no) 1996-04-22
EP0708093A1 (de) 1996-04-24
BR9504456A (pt) 1997-05-20
KR960014108A (ko) 1996-05-22
EP0708093B1 (de) 2001-01-17
US5723461A (en) 1998-03-03
FI954946A0 (fi) 1995-10-17
HU9503005D0 (en) 1995-12-28
AU3431695A (en) 1996-05-02
CN1135483A (zh) 1996-11-13
HRP950524A2 (en) 1997-10-31
DK0708093T3 (da) 2001-04-30
DE4437406A1 (de) 1996-04-25
HUT73485A (en) 1996-08-28
SK128495A3 (en) 1996-06-05
NO954139D0 (no) 1995-10-18
HK1011988A1 (zh) 1999-07-23
ES2154311T3 (es) 2001-04-01
ATE198747T1 (de) 2001-02-15
FI954946A7 (fi) 1996-04-20
ZA958783B (en) 1996-05-09
DE59508969D1 (de) 2001-02-22
NZ280258A (en) 1997-09-22

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