IL117320A - PROCESS FOR PURIFYING APOLIPOPROTEINS ApoA AND ApoE OR MIXTURES THEREOF, SUBSTANTIALLY ENDOTOXIN-FREE ApoA OR ApoE PRODUCED BY THIS PROCESS AND THE USE OF APOLIPOPROTEINS PRODUCED BY THIS PROCESS IN THE PREPARATION OF A MEDICAMENT - Google Patents

PROCESS FOR PURIFYING APOLIPOPROTEINS ApoA AND ApoE OR MIXTURES THEREOF, SUBSTANTIALLY ENDOTOXIN-FREE ApoA OR ApoE PRODUCED BY THIS PROCESS AND THE USE OF APOLIPOPROTEINS PRODUCED BY THIS PROCESS IN THE PREPARATION OF A MEDICAMENT

Info

Publication number
IL117320A
IL117320A IL11732096A IL11732096A IL117320A IL 117320 A IL117320 A IL 117320A IL 11732096 A IL11732096 A IL 11732096A IL 11732096 A IL11732096 A IL 11732096A IL 117320 A IL117320 A IL 117320A
Authority
IL
Israel
Prior art keywords
apoa
apoe
matrix
endotoxins
process according
Prior art date
Application number
IL11732096A
Other languages
English (en)
Other versions
IL117320A0 (en
Inventor
Hans Ageland
Lena Romander
Original Assignee
Esperion Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Esperion Therapeutics Inc filed Critical Esperion Therapeutics Inc
Publication of IL117320A0 publication Critical patent/IL117320A0/xx
Publication of IL117320A publication Critical patent/IL117320A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775Apolipopeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
IL11732096A 1995-03-03 1996-02-29 PROCESS FOR PURIFYING APOLIPOPROTEINS ApoA AND ApoE OR MIXTURES THEREOF, SUBSTANTIALLY ENDOTOXIN-FREE ApoA OR ApoE PRODUCED BY THIS PROCESS AND THE USE OF APOLIPOPROTEINS PRODUCED BY THIS PROCESS IN THE PREPARATION OF A MEDICAMENT IL117320A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9500778A SE9500778D0 (sv) 1995-03-03 1995-03-03 Process for producing a protein

Publications (2)

Publication Number Publication Date
IL117320A0 IL117320A0 (en) 1996-06-18
IL117320A true IL117320A (en) 2001-06-14

Family

ID=20397430

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11732096A IL117320A (en) 1995-03-03 1996-02-29 PROCESS FOR PURIFYING APOLIPOPROTEINS ApoA AND ApoE OR MIXTURES THEREOF, SUBSTANTIALLY ENDOTOXIN-FREE ApoA OR ApoE PRODUCED BY THIS PROCESS AND THE USE OF APOLIPOPROTEINS PRODUCED BY THIS PROCESS IN THE PREPARATION OF A MEDICAMENT

Country Status (15)

Country Link
US (3) US5834596A (da)
EP (1) EP0813541B1 (da)
JP (1) JPH11501046A (da)
AT (1) ATE240348T1 (da)
AU (1) AU694623B2 (da)
CA (1) CA2212125A1 (da)
DE (1) DE69628148T2 (da)
DK (1) DK0813541T3 (da)
ES (1) ES2199284T3 (da)
IL (1) IL117320A (da)
NZ (1) NZ303325A (da)
PT (1) PT813541E (da)
SE (1) SE9500778D0 (da)
WO (1) WO1996027608A1 (da)
ZA (1) ZA961679B (da)

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SE9603303D0 (sv) 1996-09-11 1996-09-11 Pharmacia & Upjohn Ab Process for purifying a protein
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US6410802B1 (en) 1999-04-01 2002-06-25 Esperion Therapeutics, Inc. Methods for synthesizing ether compounds and intermediates therefor
US8568766B2 (en) * 2000-08-24 2013-10-29 Gattadahalli M. Anantharamaiah Peptides and peptide mimetics to treat pathologies associated with eye disease
BR0115257A (pt) * 2000-11-10 2003-08-12 Proteopharma Aps Análogos de apolipoproteìna
PL372925A1 (en) * 2001-09-28 2005-08-08 Esperion Therapeutics Inc. Prevention and treatment of restenosis by local administration of drug
US20030229062A1 (en) * 2001-12-07 2003-12-11 The Regents Of The University Of California Treatments for age-related macular degeneration (AMD)
WO2003049685A2 (en) * 2001-12-07 2003-06-19 The Regents Of The University Of California Treatment for age-related macular degeneration
US7470659B2 (en) * 2001-12-07 2008-12-30 The Regents Of The University Of California Methods to increase reverse cholesterol transport in the retinal pigment epithelium (RPE) and Bruch's membrane (BM)
BR0310100A (pt) * 2002-05-17 2007-04-27 Esperion Therapeutics Inc métodos para tratar, prevenir ou reduzir a lesão de reperfusão isquêmica em um tecido ou órgão, e para prevenir ou tratar de uma condição associada com a privação de oxigênio, seguida por suprimento de oxigênio aumentado a um tecido ou órgão em necessidade disto
ES2625429T3 (es) * 2003-01-23 2017-07-19 Esperion Therapeutics Inc. Compuestos de hidroxilo y composiciones para el control del colesterol y utilizaciones correspondientes
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US20080227686A1 (en) * 2006-06-16 2008-09-18 Lipid Sciences, Inc. Novel Peptides that Promote Lipid Efflux
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AU2007284801A1 (en) 2006-08-08 2008-02-21 The Regents Of The University Of Californina Salicylanilides enhance oral delivery of therapeutic peptides
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EP3296398A1 (en) 2009-12-07 2018-03-21 Arbutus Biopharma Corporation Compositions for nucleic acid delivery
EP3494963A1 (en) 2009-12-18 2019-06-12 The University of British Columbia Methods and compositions for delivery of nucleic acids
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US20130137628A1 (en) 2010-05-11 2013-05-30 Esperion Therapeutics, Inc. Dimeric Oxidation-Resistant Apolipoprotein A1 Variants
KR20190039347A (ko) 2010-06-03 2019-04-10 알닐람 파마슈티칼스 인코포레이티드 활성제의 전달을 위한 생분해성 지질
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CA2824526C (en) 2011-01-11 2020-07-07 Alnylam Pharmaceuticals, Inc. Pegylated lipids and their use for drug delivery
HUE042314T2 (hu) 2011-02-07 2019-06-28 Cerenis Therapeutics Holding Sa Lipoprotein komplexek és azok gyártása és alkalmazásai
EP3456317B1 (en) 2011-09-27 2025-09-24 Alnylam Pharmaceuticals, Inc. Di-aliphatic substituted pegylated lipids
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CN104507953B (zh) * 2012-05-31 2018-05-18 新加坡科技研究局 通过用正电性有机添加剂处理来降低蛋白质制剂中蛋白质-污染物复合物和聚集物水平的方法
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MA41793A (fr) 2015-03-16 2018-01-23 Esperion Therapeutics Inc Associations de doses fixes comprenant du etc1002 et une ou plusieurs statines permettant de traiter ou de réduire un risque cardiovasculaire
CN107033237B (zh) * 2017-05-11 2021-07-20 深圳市卫光生物制品股份有限公司 一种人血浆载脂蛋白a-i的分离纯化方法
MX2021015936A (es) 2019-06-21 2022-04-26 Esperion Therapeutics Inc Metodos para preparar acido bempedoico y composiciones del mismo.
US20240350579A1 (en) * 2020-08-10 2024-10-24 Gel4Med, Inc. Antifungal matrix formed from peptide hydrogels

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Also Published As

Publication number Publication date
ATE240348T1 (de) 2003-05-15
ZA961679B (en) 1996-10-07
DE69628148T2 (de) 2004-01-08
SE9500778D0 (sv) 1995-03-03
US6506879B1 (en) 2003-01-14
CA2212125A1 (en) 1996-09-12
ES2199284T3 (es) 2004-02-16
DE69628148D1 (de) 2003-06-18
JPH11501046A (ja) 1999-01-26
AU4960796A (en) 1996-09-23
IL117320A0 (en) 1996-06-18
EP0813541B1 (en) 2003-05-14
US5834596A (en) 1998-11-10
WO1996027608A1 (en) 1996-09-12
EP0813541A1 (en) 1997-12-29
NZ303325A (en) 1998-12-23
US5990081A (en) 1999-11-23
DK0813541T3 (da) 2003-09-15
AU694623B2 (en) 1998-07-23
PT813541E (pt) 2003-09-30

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