IL122123A - Estrogen agonists / antagonists, their pharmaceutical preparations and their use in the preparation of drugs for the treatment of atherosclerosis - Google Patents

Estrogen agonists / antagonists, their pharmaceutical preparations and their use in the preparation of drugs for the treatment of atherosclerosis

Info

Publication number: IL122123A
Authority: IL; Israel
Prior art keywords: phenyl; compound; recited; independently selected; formula
Prior art date: 1996-11-15

Application number

IL12212397A

Other languages

English (en)

Hebrew (he)

Other versions

IL122123A0 (en

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-11-15

Filing date

1997-11-06

Publication date

2001-07-24

1997-11-06 Application filed by Pfizer filed Critical Pfizer

1998-04-05 Publication of IL122123A0 publication Critical patent/IL122123A0/xx

2001-07-24 Publication of IL122123A publication Critical patent/IL122123A/en

Links

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Classifications

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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A47—FURNITURE; DOMESTIC ARTICLES OR APPLIANCES; COFFEE MILLS; SPICE MILLS; SUCTION CLEANERS IN GENERAL
- A47J—KITCHEN EQUIPMENT; COFFEE MILLS; SPICE MILLS; APPARATUS FOR MAKING BEVERAGES
- A47J47/00—Kitchen containers, stands or the like, not provided for in other groups of this subclass; Cutting-boards, e.g. for bread
- A47J47/02—Closed containers for foodstuffs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Food Science & Technology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Plant Substances (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Steroid Compounds (AREA)
Indole Compounds (AREA)

IL12212397A 1996-11-15 1997-11-06 Estrogen agonists / antagonists, their pharmaceutical preparations and their use in the preparation of drugs for the treatment of atherosclerosis IL122123A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US3127396P	1996-11-15	1996-11-15

Publications (2)

Publication Number	Publication Date
IL122123A0 IL122123A0 (en)	1998-04-05
IL122123A true IL122123A (en)	2001-07-24

Family

ID=21858549

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL12212397A IL122123A (en)	1996-11-15	1997-11-06	Estrogen agonists / antagonists, their pharmaceutical preparations and their use in the preparation of drugs for the treatment of atherosclerosis

Country Status (17)

Country	Link
US (1)	US6034102A (de)
EP (1)	EP0842661B1 (de)
JP (1)	JP3287793B2 (de)
KR (1)	KR100367793B1 (de)
AT (1)	ATE202702T1 (de)
AU (1)	AU740378B2 (de)
CA (1)	CA2221114C (de)
DE (1)	DE69705480T2 (de)
DK (1)	DK0842661T3 (de)
ES (1)	ES2158452T3 (de)
GR (1)	GR3036455T3 (de)
HU (1)	HU223942B1 (de)
IL (1)	IL122123A (de)
MY (1)	MY114586A (de)
NZ (1)	NZ329174A (de)
PT (1)	PT842661E (de)
ZA (1)	ZA9710292B (de)

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IL126447A (en) *	1998-10-04	2004-09-27	Vascular Biogenics Ltd	An immune preparation that confers tolerance in oral administration and its use in the prevention and / or treatment of atherosclerosis
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WO2000055137A1 (en) *	1999-03-17	2000-09-21	Signal Pharmaceuticals, Inc.	Compounds and methods for modulation of estrogen receptors
US6593322B1 (en)	1999-03-17	2003-07-15	Signal Pharmaceuticals, Inc.	Compounds and methods for modulation of estrogen receptors
CO5170459A1 (es) *	1999-06-01	2002-06-27	Pfizer Prod Inc	Terapia transdermica con agonistas-antagonistas de estrogenos len-ol, administrados mediante medios transdermicos
EP1113007A1 (de) *	1999-12-24	2001-07-04	Pfizer Inc.	Tetrahydroisochinolin-Verbindungen zur Verwendung als Östrogen-Agonisten/-Antagonisten
ATE253910T1 (de) *	2000-06-01	2003-11-15	Watson Pharmaceuticals Inc	Transdermale verabreichung von lasofoxifen
AU2001288682A1 (en)	2000-08-30	2002-03-13	Chemocentryx, Inc.	Inhibition of cmv infection and dissemination
TWI303990B (en)	2000-10-17	2008-12-11	Pfizer Prod Inc	New use of estrogen agonists/antagonists for improving vascular health
AU2002218461B2 (en)	2000-11-24	2006-09-07	Vascular Biogenics Ltd	Methods employing and compositions containing defined oxidized phospholipids for prevention and treatment of atherosclerosis
WO2002047723A1 (en) *	2000-12-11	2002-06-20	Takeda Chemical Industries, Ltd.	Medicinal compositions having improved water-solubility
CA2437201C (en) *	2001-02-02	2008-11-18	Chemocentryx, Inc.	Methods and compositions useful for stimulating an immune response
WO2003018549A2 (en) *	2001-08-30	2003-03-06	Chemocentryx, Inc.	Bicyclic compounds as inhibitors of chemokine binding to us28
AU2005314089B2 (en) *	2004-12-08	2011-03-03	Cedars-Sinai Medical Center	Methods for diagnosis and treatment of Crohn's disease
US20090068207A1 (en) *	2005-04-15	2009-03-12	Vascular Biogenics Ltd.	Compositions Containing Beta 2-Glycoprotein I-Derived Peptides for the Prevention and/or Treatment of Vascular Disease
US20100021917A1 (en) *	2007-02-14	2010-01-28	Cedars-Sinai Medical Center	Methods of using genes and genetic variants to predict or diagnose inflammatory bowel disease
US20100190162A1 (en) *	2007-02-26	2010-07-29	Cedars-Sinai Medical Center	Methods of using single nucleotide polymorphisms in the tl1a gene to predict or diagnose inflammatory bowel disease
US20100015156A1 (en) *	2007-03-06	2010-01-21	Cedars-Sinai Medical Center	Diagnosis of inflammatory bowel disease in children
US8486640B2 (en)	2007-03-21	2013-07-16	Cedars-Sinai Medical Center	Ileal pouch-anal anastomosis (IPAA) factors in the treatment of inflammatory bowel disease
WO2008134569A2 (en) *	2007-04-26	2008-11-06	Cedars-Sinai Medical Center	Diagnosis and treatment of inflammatory bowel disease in the puerto rican population
US20100144903A1 (en) *	2007-05-04	2010-06-10	Cedars-Sinai Medical Center	Methods of diagnosis and treatment of crohn's disease
US20110177969A1 (en) *	2008-10-01	2011-07-21	Cedars-Sinai Medical Center	The role of il17rd and the il23-1l17 pathway in crohn's disease
US20110189685A1 (en) *	2008-10-22	2011-08-04	Cedars-Sinai Medical Center	Methods of using jak3 genetic variants to diagnose and predict crohn's disease
US20110229471A1 (en) *	2008-11-26	2011-09-22	Cedars-Sinai Medical Center	Methods of determining responsiveness to anti-tnf alpha therapy in inflammatory bowel disease
US9580752B2 (en)	2008-12-24	2017-02-28	Cedars-Sinai Medical Center	Methods of predicting medically refractive ulcerative colitis (MR-UC) requiring colectomy
KR20240122922A (ko)	2013-03-27	2024-08-13	세다르스-신나이 메디칼 센터	Tl1a 기능 및 관련된 신호전달 경로의 저해에 의한 섬유증 및 염증의 완화 및 반전
EP4105236A1 (de)	2013-07-19	2022-12-21	Cedars-Sinai Medical Center	Anti-tl1a (tnfsf15) antikörper zur behandlung von entzündlichen darmerkrankungen
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DE4320898A1 (de) *	1993-06-24	1995-01-05	Denecke Rainer Dr Med Vet	Präparat zur Therapie und Prophylaxe von Erkrankungen, die bei Imbalancen von Plasmalipiden auftreten
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1997
- 1997-10-21 US US08/955,312 patent/US6034102A/en not_active Expired - Fee Related
- 1997-11-05 DK DK97308862T patent/DK0842661T3/da active
- 1997-11-05 ES ES97308862T patent/ES2158452T3/es not_active Expired - Lifetime
- 1997-11-05 EP EP97308862A patent/EP0842661B1/de not_active Expired - Lifetime
- 1997-11-05 PT PT97308862T patent/PT842661E/pt unknown
- 1997-11-05 DE DE69705480T patent/DE69705480T2/de not_active Expired - Fee Related
- 1997-11-05 AT AT97308862T patent/ATE202702T1/de not_active IP Right Cessation
- 1997-11-06 IL IL12212397A patent/IL122123A/en not_active IP Right Cessation
- 1997-11-13 NZ NZ329174A patent/NZ329174A/xx unknown
- 1997-11-13 CA CA002221114A patent/CA2221114C/en not_active Expired - Fee Related
- 1997-11-13 MY MYPI97005407A patent/MY114586A/en unknown
- 1997-11-14 KR KR1019970060003A patent/KR100367793B1/ko not_active Expired - Fee Related
- 1997-11-14 HU HU9702040A patent/HU223942B1/hu not_active IP Right Cessation
- 1997-11-14 ZA ZA9710292A patent/ZA9710292B/xx unknown
- 1997-11-17 JP JP31522797A patent/JP3287793B2/ja not_active Expired - Fee Related
- 1997-11-17 AU AU45237/97A patent/AU740378B2/en not_active Ceased
2001
- 2001-08-27 GR GR20010401305T patent/GR3036455T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
ATE202702T1 (de)	2001-07-15
US6034102A (en)	2000-03-07
ZA9710292B (en)	1999-05-17
DK0842661T3 (da)	2001-09-24
CA2221114A1 (en)	1998-05-15
CA2221114C (en)	2003-10-28
AU4523797A (en)	1998-05-21
AU740378B2 (en)	2001-11-01
GR3036455T3 (en)	2001-11-30
HUP9702040A1 (hu)	2000-11-28
DE69705480T2 (de)	2001-10-31
DE69705480D1 (de)	2001-08-09
PT842661E (pt)	2001-10-30
JP3287793B2 (ja)	2002-06-04
HU9702040D0 (en)	1998-01-28
MY114586A (en)	2002-11-30
KR19980042432A (ko)	1998-08-17
NZ329174A (en)	2000-10-27
IL122123A0 (en)	1998-04-05
EP0842661A3 (de)	1998-09-02
ES2158452T3 (es)	2001-09-01
EP0842661B1 (de)	2001-07-04
HU223942B1 (hu)	2005-03-29
EP0842661A2 (de)	1998-05-20
JPH10147527A (ja)	1998-06-02
KR100367793B1 (ko)	2003-04-21

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AU2013201986A1 (en)	2013-04-18	Capsule Formulation Of Pirfenidone And Pharmaceutically Acceptable Excipients
JPWO2006051757A1 (ja)	2008-05-29	虚血性心疾患もしくは虚血性心筋症の治療剤または予防剤