IL125590A - Peptide immunogens, process for their preparation and use thereof as vaccines against allergies - Google Patents

Peptide immunogens, process for their preparation and use thereof as vaccines against allergies

Info

Publication number
IL125590A
IL125590A IL12559097A IL12559097A IL125590A IL 125590 A IL125590 A IL 125590A IL 12559097 A IL12559097 A IL 12559097A IL 12559097 A IL12559097 A IL 12559097A IL 125590 A IL125590 A IL 125590A
Authority
IL
Israel
Prior art keywords
preparation
vaccines against
peptide immunogens
against allergies
allergies
Prior art date
Application number
IL12559097A
Other languages
English (en)
Other versions
IL125590A0 (en
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26308839&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL125590(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9604412.8A external-priority patent/GB9604412D0/en
Priority claimed from GBGB9617702.7A external-priority patent/GB9617702D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of IL125590A0 publication Critical patent/IL125590A0/xx
Publication of IL125590A publication Critical patent/IL125590A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4283—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
    • C07K16/4291—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig against IgE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/528—CH4 domain

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL12559097A 1996-03-01 1997-02-28 Peptide immunogens, process for their preparation and use thereof as vaccines against allergies IL125590A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9604412.8A GB9604412D0 (en) 1996-03-01 1996-03-01 Organic compounds
GBGB9617702.7A GB9617702D0 (en) 1996-08-22 1996-08-22 Organic compounds
PCT/EP1997/001013 WO1997031948A1 (en) 1996-03-01 1997-02-28 Peptide immunogens for vaccination against and treatment of allergy

Publications (2)

Publication Number Publication Date
IL125590A0 IL125590A0 (en) 1999-03-12
IL125590A true IL125590A (en) 2001-08-26

Family

ID=26308839

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12559097A IL125590A (en) 1996-03-01 1997-02-28 Peptide immunogens, process for their preparation and use thereof as vaccines against allergies

Country Status (24)

Country Link
US (1) US6610297B1 (de)
EP (1) EP0885244B2 (de)
JP (2) JP3421970B2 (de)
KR (2) KR100584051B1 (de)
CN (1) CN1174998C (de)
AT (1) ATE230417T1 (de)
AU (1) AU719609B2 (de)
BR (1) BR9707819A (de)
CA (1) CA2245497C (de)
CY (1) CY2457B1 (de)
CZ (1) CZ299551B6 (de)
DE (1) DE69718150T3 (de)
DK (1) DK0885244T4 (de)
ES (1) ES2190799T5 (de)
HU (1) HUP9901109A3 (de)
IL (1) IL125590A (de)
NO (1) NO321043B1 (de)
NZ (1) NZ331651A (de)
PL (1) PL187209B1 (de)
RU (1) RU2193413C2 (de)
SI (1) SI0885244T2 (de)
SK (1) SK284856B6 (de)
TR (1) TR199801722T2 (de)
WO (1) WO1997031948A1 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1621209A3 (de) * 1998-11-02 2006-04-19 Resistentia Pharmaceuticals AB Vakzinen die auf Domänen von chimären Immunoglobulin E Peptide basieren
US6913749B2 (en) 1998-11-02 2005-07-05 Resistentia Pharmaceuticals Ab Immunogenic polypeptides for inducing anti-self IgE responses
MXPA01005389A (es) 1998-11-30 2003-03-27 Cytos Biotechnology Ag Presentacion molecular ordenada de antigenos, metodos de preparacion y uso.
WO2000050077A1 (en) * 1999-02-25 2000-08-31 Smithkline Beecham Biologicals S.A. Immunogens comprising a peptide and a carrier derived from h.influenzae protein d
IL145025A0 (en) * 1999-02-25 2002-06-30 Smithkline Beecham Biolog Epitopes or mimotopes derived from the c-epsilon-3 or c-epsilon-4 domains of ige, antagonists thereof, and their therapeutic uses
GB9908533D0 (en) * 1999-04-14 1999-06-09 Novartis Ag Organic compounds
AU2001252262B2 (en) * 2000-04-13 2006-02-02 Biolife Science Forschungs-und Entwicklungsgesellschaft m.b.H Vaccine against cancerous diseases which is based on mimotopes of antigens expressed on tumor cells
EP1278542A2 (de) 2000-05-05 2003-01-29 Cytos Biotechnology AG Molekuläre antigenarrays und impfstoffe
EP2065052A3 (de) 2000-08-30 2009-08-19 Pfizer Products Inc. Anti-IgE Vakzine
US7094409B2 (en) 2001-01-19 2006-08-22 Cytos Biotechnology Ag Antigen arrays for treatment of allergic eosinophilic diseases
US7128911B2 (en) 2001-01-19 2006-10-31 Cytos Biotechnology Ag Antigen arrays for treatment of bone disease
US7264810B2 (en) 2001-01-19 2007-09-04 Cytos Biotechnology Ag Molecular antigen array
EP1236740B1 (de) * 2001-02-28 2012-07-18 Bio Life Science Forschungs- und Entwicklungsges.m.b.H. Vakzine gegen Krebserkrankungen, die mit dem HER-2/neu Onkogen assoziiert sind
EP1239032A1 (de) * 2001-03-02 2002-09-11 Société des Produits Nestlé S.A. Milchsäurebakterien als Mitteln zur Behandlung und Vorbeugung von Allergie
JP2003047482A (ja) 2001-05-22 2003-02-18 Pfizer Prod Inc 非アナフィラキシー誘発性ＩｇＥワクチン
WO2003015716A2 (en) 2001-08-13 2003-02-27 Ige Therapeutics, Inc. Immunoglobulin e vaccines and methods of use thereof
US7115266B2 (en) 2001-10-05 2006-10-03 Cytos Biotechnology Ag Angiotensin peptide-carrier conjugates and uses thereof
ATE361097T1 (de) * 2002-01-15 2007-05-15 Bio Life Science Forschungs & Entwicklungsgesellschaft Mbh Orale vakzinierung mit dem tumor-antigen-mimotop gln-met-trp-ala-pro-gln-trp-gly-pro-asp
AU2003246690B2 (en) 2002-07-17 2010-03-11 Cytos Biotechnology Ag Molecular antigen arrays using a virus like particle derived from the AP205 coat protein
NZ537003A (en) 2002-07-18 2008-03-28 Cytos Biotechnology Ag Hapten-carrier conjugates comprising virus like particles and uses thereof
BR0312792A (pt) 2002-07-19 2005-05-03 Cytos Biotechnology Ag Composições de vacinas contendo séries antigênicas de amilóide beta1-6
PT1534335E (pt) 2002-08-14 2012-02-28 Macrogenics Inc Anticorpos específicos de fcγriib e processos para a sua utilização
US20050065136A1 (en) * 2003-08-13 2005-03-24 Roby Russell R. Methods and compositions for the treatment of infertility using dilute hormone solutions
WO2005105106A2 (en) * 2004-04-21 2005-11-10 Roby Russell R Hormone treatment of macular degeneration
US20060025390A1 (en) * 2004-07-28 2006-02-02 Roby Russell R Treatment of hormone allergy and related symptoms and disorders
DK1629850T4 (da) * 2004-08-24 2013-07-01 Nutricia Nv Næringssammensætning indeholdende ufordøjelige oligosaccharider
ITMI20052517A1 (it) * 2005-12-29 2007-06-30 Lofarma Spa Varianbtio ipoallergeniche dell'allergene maggiore bet v 1 di polline di betula verrucosa
EP2029173B1 (de) 2006-06-26 2016-07-20 MacroGenics, Inc. Fc-riib-spezifische antikörper und verfahren zu ihrer anwendung
RU2340348C1 (ru) * 2007-04-04 2008-12-10 Государственное учреждение Научно-исследовательский институт клинической иммунологии СО РАМН Способ лечения атопического дерматита
EP2012122A1 (de) * 2007-07-06 2009-01-07 Medigene AG Strukturproteine von mutierten Parvoviren als Impfstoffe
US8865179B2 (en) * 2008-01-26 2014-10-21 Swey-Shen Alexchen Aptameric IgE peptides in a protein scaffold as an allergy vaccine
BRPI0922561A2 (pt) 2008-12-09 2020-08-11 Pfizer Vaccines Llc vacina de peptídeo de ch3 da ige.
EP2575868A1 (de) 2010-06-07 2013-04-10 Pfizer Vaccines LLC Ige-ch3-peptidimpfstoff
RU2761431C9 (ru) * 2020-10-26 2022-04-18 Федеральное государственное бюджетное учреждение "Государственный научный центр "Институт иммунологии" Федерального медико-биологического агентства России (ФГБУ "ГНЦ Институт иммунологии" ФМБА России) Рекомбинантный полипептид на основе аллергена пыльцы березы и аллергена яблока в качестве вакцины от аллергии

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2602443A1 (de) 1975-04-04 1976-10-21 Univ California Biologisch aktive polypeptide
US4171299A (en) 1975-04-04 1979-10-16 The Regents Of The University Of California Polypeptide agents for blocking the human allergic response
DE2861593D1 (en) 1977-06-29 1982-03-11 Beecham Group Plc Peptides, pharmaceutical compositions containing the peptides and a process for the preparation of the peptides
JPS5944399A (ja) 1982-09-07 1984-03-12 Takeda Chem Ind Ltd 新規ｄｎａ
GB8616166D0 (en) * 1986-07-02 1986-08-06 Research Corp Ltd Polypeptide competitor
US4892827A (en) 1986-09-24 1990-01-09 The United States Of America As Represented By The Department Of Health And Human Services Recombinant pseudomonas exotoxins: construction of an active immunotoxin with low side effects
EP0269455A3 (de) 1986-11-28 1989-09-06 Takeda Chemical Industries, Ltd. Hochgereinigtes Fusionsprotein, das ein menschliches IgE Fc-Fragment enthält, sowie dessen Herstellung
AU1484688A (en) 1987-02-20 1988-09-14 Imclone Systems, Inc. Monoclonal antibodies in vaccine formulations
CA1336818C (en) 1987-04-16 1995-08-29 International Institute Of Cellular And Molecular Pathology Treatment of allergy and composition thereof
AU635492B2 (en) 1987-10-13 1993-03-25 Telik, Inc. Method to produce immunodiagnostic reagents
GB8727045D0 (en) 1987-11-19 1987-12-23 Research Corp Ltd Immunoglobulin e competitor
US5342924A (en) 1987-12-31 1994-08-30 Tanox Biosystems, Inc. Extracellular segments of human ε immunoglobulin anchoring peptides and antibodies specific therefor
US5449760A (en) 1987-12-31 1995-09-12 Tanox Biosystems, Inc. Monoclonal antibodies that bind to soluble IGE but do not bind IGE on IGE expressing B lymphocytes or basophils
GB8910263D0 (en) 1989-05-04 1989-06-21 Ciba Geigy Ag Monoclonal antibodies specific for an immunoglobulin isotype
GB8913737D0 (en) 1989-06-15 1989-08-02 Univ Birmingham A novel anti-allergy treatment
DE69126607T2 (de) 1990-01-23 1998-01-15 Tanox Biosystems, Inc., Houston, Tex. Extrazelluläre teilstücke humaner ige-immunoglobulin-ankerpeptide und dafür spezifische antikörper
JPH05508835A (ja) 1990-05-25 1993-12-09 ペプチド・セラピューティクス・リミテッド 慢性関節リウマチの免疫診断検定法
US5258289A (en) 1990-09-05 1993-11-02 Davis Claude G Method for the selecting of genes encoding catalytic antibodies
GB9101550D0 (en) 1991-01-24 1991-03-06 Mastico Robert A Antigen-presenting chimaeric protein
EP1260521B1 (de) * 1991-08-14 2007-11-21 Genentech Inc. Immunglobulinvarianten für spezifische Fc-epsilon Rezeptoren
US5965709A (en) * 1991-08-14 1999-10-12 Genentech, Inc. IgE antagonists
SE9102808L (sv) * 1991-09-26 1993-03-27 Lars T Hellman Inst F Immunolo Vaccin, foer humant bruk, vars avsedda effekt aer att lindra symptomen eller foerhindra uppkomsten av ige-medierade allergiska reaktioner
GB9125024D0 (en) 1991-11-25 1992-01-22 Kirby Julian Rheumatoid arthritus treatment
JPH06113881A (ja) 1992-10-07 1994-04-26 Snow Brand Milk Prod Co Ltd ヒト型モノクローナル抗ペプチド抗体及びこれをコードするｄｎａ
US5759551A (en) 1993-04-27 1998-06-02 United Biomedical, Inc. Immunogenic LHRH peptide constructs and synthetic universal immune stimulators for vaccines
ES2180576T3 (es) 1993-04-27 2003-02-16 United Biomedical Inc Construcciones peptidicas de lhrh inmunogenicas y estimuladores de inmunidad universales sinteticos para vacunas.
US5843941A (en) 1993-05-14 1998-12-01 Genentech, Inc. Ras farnesyl transferase inhibitors
GB9320897D0 (en) 1993-10-11 1993-12-01 Peptide Therapeutics Ltd Compounds useful in anti-allergy treatment
GB9324013D0 (en) * 1993-11-22 1994-01-12 3I Res Expl Ltd Polypeptides
FR2715304B1 (fr) * 1994-01-26 1996-04-26 Merieux Serums Vaccins Pasteur Vaccin anti-allergique.
WO1995026365A1 (en) * 1994-03-28 1995-10-05 United Biomedical, Inc. Synthetic peptide based immunogens for the treatment of allergy
AU3002695A (en) 1994-07-08 1996-02-09 King's College Ige antagonists
EP0787150A1 (de) 1994-10-25 1997-08-06 United Biomedical, Inc. Synthetische membrananker-peptidimmunogene gegen ige für die behandlung der allergie
WO1998024808A2 (en) 1996-12-06 1998-06-11 THE UNITED STATES OF AMERICA represented by THE SECRETARY DEPARTMENT OF HEALTH & HUMAN SERVICES, THE NATIONAL INSTITUTES OF HEALTH INHIBITION OF IgE-MEDIATED ALLERGIES BY A HUMAN IgE-DERIVED OLIGOPEPTIDE
EP0955311A3 (de) 1998-04-09 2000-08-16 Idexx Laboratories, Inc. Peptidscher Impfstoff für Hundenallergie
TWI229679B (en) 1998-06-20 2005-03-21 United Biomedical Inc Artificial T helper cell epitopes as immune stimulators for synthetic peptide immunogens

Also Published As

Publication number Publication date
AU1879697A (en) 1997-09-16
SI0885244T2 (sl) 2008-10-31
WO1997031948A1 (en) 1997-09-04
JP2003231696A (ja) 2003-08-19
DE69718150T3 (de) 2009-03-05
NZ331651A (en) 2000-01-28
DK0885244T4 (da) 2008-06-16
HUP9901109A3 (en) 1999-11-29
AU719609B2 (en) 2000-05-11
CY2457B1 (en) 2005-06-03
SI0885244T1 (en) 2003-06-30
PL187209B1 (pl) 2004-06-30
KR100498198B1 (ko) 2005-09-09
KR19990087425A (ko) 1999-12-27
CA2245497C (en) 2009-02-24
EP0885244A1 (de) 1998-12-23
CA2245497A1 (en) 1997-09-04
JP3421970B2 (ja) 2003-06-30
IL125590A0 (en) 1999-03-12
SK118198A3 (en) 1999-03-12
CN1213380A (zh) 1999-04-07
ES2190799T3 (es) 2003-08-16
HUP9901109A2 (hu) 1999-07-28
CZ299551B6 (cs) 2008-08-27
EP0885244B1 (de) 2003-01-02
KR20050049509A (ko) 2005-05-25
DE69718150D1 (de) 2003-02-06
BR9707819A (pt) 1999-07-27
DK0885244T3 (da) 2003-04-22
RU2193413C2 (ru) 2002-11-27
CN1174998C (zh) 2004-11-10
KR100584051B1 (ko) 2006-05-30
US6610297B1 (en) 2003-08-26
PL328858A1 (en) 1999-03-01
NO983999D0 (no) 1998-08-31
SK284856B6 (sk) 2006-01-05
CZ277198A3 (cs) 1998-12-16
ATE230417T1 (de) 2003-01-15
DE69718150T2 (de) 2003-08-21
NO983999L (no) 1998-11-02
TR199801722T2 (xx) 1998-12-21
EP0885244B2 (de) 2008-04-16
ES2190799T5 (es) 2008-08-16
JP2000502571A (ja) 2000-03-07
NO321043B1 (no) 2006-03-06
HK1014962A1 (en) 1999-10-08

Similar Documents

Publication Publication Date Title
CY2457B1 (en) Peptide immunogens for vaccination against and treatment of allergy.
CY2612B2 (en) Compounds for immunotherapy and diagnosis of tuberculosis
IL148079A0 (en) Human ctla-4 antibodies and compositions containing the same
AUPN568095A0 (en) Anti-Galalpha(1,3)Gal antibody binding peptides
DE69840383D1 (de) Ctl epitope des epstein-barr virus
WO2001039796A3 (en) Vaccine for the prevention and treatment of alzheimer's and amyloid related diseases
AU4612093A (en) Soluble ligands for CD40
PT835133E (pt) Composições recombinantes de poxvírus-raiva e composições de combinação e suas utilizações
EP1194164A4 (de) Prion protein peptide und deren verwendung
WO2001058485A3 (en) Prophylactic and therapeutic antibodies against vaccina virus antigens
AU6921300A (en) Novel glycoconjugates, glycoamino, acids, intermediates thereto, and uses thereof
CA2109977A1 (en) Giardia vaccines
WO2000052045A3 (en) Mage-3 derived immunogenic peptides presented by mhc of class ii and the use thereof
DK0938329T3 (da) Immunogen TLP sammensætning
EP1039931A4 (de) Multivalente rekombinante antikörper zur behandlung von hrv infektionen

Legal Events

Date Code Title Description
KB Patent renewed
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees