IL127044A - Use of p-aminophenol derivatives for the preparation of pharmaceutical compositions useful in the treatment of neurodegenertive diseases - Google Patents

Use of p-aminophenol derivatives for the preparation of pharmaceutical compositions useful in the treatment of neurodegenertive diseases

Info

Publication number
IL127044A
IL127044A IL12704497A IL12704497A IL127044A IL 127044 A IL127044 A IL 127044A IL 12704497 A IL12704497 A IL 12704497A IL 12704497 A IL12704497 A IL 12704497A IL 127044 A IL127044 A IL 127044A
Authority
IL
Israel
Prior art keywords
neurodegenertive
diseases
preparation
treatment
pharmaceutical compositions
Prior art date
Application number
IL12704497A
Other languages
English (en)
Other versions
IL127044A0 (en
Original Assignee
Angelini Ricereche S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angelini Ricereche S P A filed Critical Angelini Ricereche S P A
Publication of IL127044A0 publication Critical patent/IL127044A0/xx
Publication of IL127044A publication Critical patent/IL127044A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL12704497A 1996-05-21 1997-05-15 Use of p-aminophenol derivatives for the preparation of pharmaceutical compositions useful in the treatment of neurodegenertive diseases IL127044A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT96MI001013A IT1282736B1 (it) 1996-05-21 1996-05-21 Uso di derivati del p-amminofenolo per preparare composizioni farmaceutiche utili nel trattamento di malattie neurodegenerative
PCT/EP1997/002708 WO1997044020A1 (en) 1996-05-21 1997-05-15 Use of p-aminophenol derivatives for the preparation of pharmaceutical compositions useful in the treatment of neurodegenerative diseases

Publications (2)

Publication Number Publication Date
IL127044A0 IL127044A0 (en) 1999-09-22
IL127044A true IL127044A (en) 2001-03-19

Family

ID=11374289

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12704497A IL127044A (en) 1996-05-21 1997-05-15 Use of p-aminophenol derivatives for the preparation of pharmaceutical compositions useful in the treatment of neurodegenertive diseases

Country Status (19)

Country Link
US (1) US6043285A (da)
EP (1) EP0946162B1 (da)
JP (1) JP2000510859A (da)
AT (1) ATE252897T1 (da)
AU (1) AU723004B2 (da)
CZ (1) CZ295875B6 (da)
DE (1) DE69725879T2 (da)
DK (1) DK0946162T3 (da)
EA (1) EA003251B1 (da)
ES (1) ES2208909T3 (da)
HU (1) HU225536B1 (da)
IL (1) IL127044A (da)
IT (1) IT1282736B1 (da)
NZ (1) NZ333232A (da)
PT (1) PT946162E (da)
SK (1) SK284860B6 (da)
TR (1) TR199802384T2 (da)
WO (1) WO1997044020A1 (da)
ZA (1) ZA974387B (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI962356A1 (it) * 1996-11-13 1998-05-13 Uni Degli Studi Di Brescia D I Uso di composti derivati da molecole ad attivita' antinfiammatoria di tipo non steroideo per la prevenzione e il trattamento di
DE19911626A1 (de) * 1999-03-16 2000-09-28 Strathmann Ag & Co Induktion antiinflammatorisch wirkender Proteine durch Ammoniumionen bzw. Amino-Reste
BR9904931A (pt) * 1999-10-18 2001-06-12 Sergio Teixeira Ferreira Inibição de amiloidoses
US6664297B1 (en) * 2000-10-18 2003-12-16 Universidade Federal Do Rio De Janeiro Methods for inhibition and dissolution of amyloidoses by administration of compositions comprising 2,4-dinitrophenol
WO2004034963A2 (en) * 2002-05-17 2004-04-29 Eisai Co., Ltd. Methods and compositions using cholinesterase inhibitors
GB0310300D0 (en) * 2003-05-06 2003-06-11 Univ Belfast Nanocomposite drug delivery composition
US20090238763A1 (en) 2006-07-09 2009-09-24 Chongxi Yu High penetration compositions and uses thereof
US20090221703A1 (en) * 2006-07-09 2009-09-03 Chongxi Yu High penetration composition and uses thereof
ES2670407T3 (es) * 2006-09-03 2018-05-30 Techfields Biochem Co. Ltd Profármacos de acetaminofén solubles en agua cargados positivamente y compuestos relacionados con una tasa de penetración de la piel muy rápida
KR20150058566A (ko) * 2007-06-04 2015-05-28 테크필즈 인크 매우 높은 피부 및 막 침투율을 가지는 ｎｓａｉａ 약물전구체 및 이들의 새로운 의약적 용도
EP2291084A4 (en) 2008-05-20 2012-04-25 Neurogesx Inc CARBONATE PRODRUGS AND METHOD FOR THEIR USE
JP5757864B2 (ja) 2008-05-20 2015-08-05 ニューロジェシックス， インコーポレイテッド 水溶性アセトアミノフェン類似体
BR122021011394B1 (pt) 2008-12-04 2021-09-28 Chongxi Yu Composição de alta penetração de um fármaco principal, e uso de uma hpc
CN111012914A (zh) 2012-01-18 2020-04-17 苏州泰飞尔医药有限公司 治疗肺部疾病的高穿透力前药组合物和医药组合物
JP5855599B2 (ja) * 2013-04-30 2016-02-09 テックフィールズ バイオケム カンパニー リミテッド 非常に速い皮膚浸透率を有するアセトアミノフェン及び関連化合物の正荷電水溶性プロドラッグ
JP5997658B2 (ja) * 2013-05-08 2016-09-28 テックフィールズ インコーポレイテッド 非常に速い皮膚及び膜浸透速度を有するｎｓａｉａプロドラッグ及びその新規医薬使用
JP6165816B2 (ja) * 2015-10-01 2017-07-19 テックフィールズ バイオケム カンパニー リミテッド 非常に速い皮膚浸透率を有するアセトアミノフェン及び関連化合物の正荷電水溶性プロドラッグ
CN115835862B (zh) * 2020-07-10 2026-01-02 广东横琴新创益生物医药有限公司 治疗阿尔茨海默病的莫达非尼组合

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5192753A (en) * 1991-04-23 1993-03-09 Mcgeer Patrick L Anti-rheumatoid arthritic drugs in the treatment of dementia
US5472983A (en) * 1994-04-14 1995-12-05 Centaur Pharmaceuticals, Inc. Benzamide-containing pharmaceutical compositions
US5643960A (en) * 1994-04-15 1997-07-01 Duke University Method of delaying onset of alzheimer's disease symptoms
US5756548A (en) * 1995-04-03 1998-05-26 Centaur Pharmaceuticals, Inc. Acetamidobenzamide compounds for neurodegenerative disorders

Also Published As

Publication number Publication date
SK284860B6 (sk) 2006-01-05
ZA974387B (en) 1997-12-23
EP0946162B1 (en) 2003-10-29
AU3092397A (en) 1997-12-09
EA199801028A1 (ru) 1999-06-24
ATE252897T1 (de) 2003-11-15
SK159898A3 (en) 2000-04-10
HUP9904027A3 (en) 2000-07-28
DE69725879T2 (de) 2004-09-02
CZ295875B6 (cs) 2005-11-16
DE69725879D1 (de) 2003-12-04
HU225536B1 (en) 2007-02-28
CZ374998A3 (cs) 1999-04-14
DK0946162T3 (da) 2004-03-01
TR199802384T2 (xx) 1999-03-22
EA003251B1 (ru) 2003-02-27
NZ333232A (en) 2000-08-25
AU723004B2 (en) 2000-08-17
ITMI961013A1 (it) 1997-11-21
HUP9904027A2 (hu) 2000-05-28
IT1282736B1 (it) 1998-03-31
ITMI961013A0 (da) 1996-05-21
WO1997044020A1 (en) 1997-11-27
ES2208909T3 (es) 2004-06-16
JP2000510859A (ja) 2000-08-22
EP0946162A1 (en) 1999-10-06
US6043285A (en) 2000-03-28
PT946162E (pt) 2004-03-31
IL127044A0 (en) 1999-09-22

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees