IL128601A - 7alpha-(epsilon-AMINOALKYL) ESTRATRIENES, PROCESS FOR PREPARING THE SAME, PHARMACEUTICAL PREPARATIONS CONTAINING SAID 7alpha-(epsilon-AMINOALKYL) ESTRATRIENES AND THEIR USE FOR PREPARING MEDICAMENTS - Google Patents

7alpha-(epsilon-AMINOALKYL) ESTRATRIENES, PROCESS FOR PREPARING THE SAME, PHARMACEUTICAL PREPARATIONS CONTAINING SAID 7alpha-(epsilon-AMINOALKYL) ESTRATRIENES AND THEIR USE FOR PREPARING MEDICAMENTS

Info

Publication number
IL128601A
IL128601A IL12860197A IL12860197A IL128601A IL 128601 A IL128601 A IL 128601A IL 12860197 A IL12860197 A IL 12860197A IL 12860197 A IL12860197 A IL 12860197A IL 128601 A IL128601 A IL 128601A
Authority
IL
Israel
Prior art keywords
estratrienes
7alpha
epsilon
aminoalkyl
preparing
Prior art date
Application number
IL12860197A
Other languages
English (en)
Other versions
IL128601A0 (en
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of IL128601A0 publication Critical patent/IL128601A0/xx
Publication of IL128601A publication Critical patent/IL128601A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C07J53/008—3 membered carbocyclic rings in position 15/16
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/006—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL12860197A 1996-08-20 1997-08-20 7alpha-(epsilon-AMINOALKYL) ESTRATRIENES, PROCESS FOR PREPARING THE SAME, PHARMACEUTICAL PREPARATIONS CONTAINING SAID 7alpha-(epsilon-AMINOALKYL) ESTRATRIENES AND THEIR USE FOR PREPARING MEDICAMENTS IL128601A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19635525A DE19635525A1 (de) 1996-08-20 1996-08-20 7alpha-(xi-Aminoalkyl)-estratriene, Verfahren zu deren Herstellung, pharmazeutische Präparate, die diese 7alpha(xi-Aminoalkyl-estratriene enthalten sowie deren Verwendung zur Herstellung von Arzneimitteln
PCT/EP1997/004517 WO1998007740A1 (fr) 1996-08-20 1997-08-20 7α-(κ-AMINOALKYL)-ESTRATRIENES, LEUR PROCEDE DE PRODUCTION, PREPARATIONS PHARMACEUTIQUES LES CONTENANT, AINSI QUE LEUR UTILISATION POUR LA FABRICATION DE MEDICAMENTS

Publications (2)

Publication Number Publication Date
IL128601A0 IL128601A0 (en) 2000-01-31
IL128601A true IL128601A (en) 2003-07-31

Family

ID=7804367

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12860197A IL128601A (en) 1996-08-20 1997-08-20 7alpha-(epsilon-AMINOALKYL) ESTRATRIENES, PROCESS FOR PREPARING THE SAME, PHARMACEUTICAL PREPARATIONS CONTAINING SAID 7alpha-(epsilon-AMINOALKYL) ESTRATRIENES AND THEIR USE FOR PREPARING MEDICAMENTS

Country Status (29)

Country Link
EP (1) EP0920441B1 (fr)
JP (1) JP2001503024A (fr)
KR (1) KR20000068261A (fr)
CN (1) CN1231670A (fr)
AR (1) AR009278A1 (fr)
AT (1) ATE231882T1 (fr)
AU (1) AU728843B2 (fr)
BG (1) BG62972B1 (fr)
BR (1) BR9711328A (fr)
CA (1) CA2263708A1 (fr)
CZ (1) CZ57999A3 (fr)
DE (2) DE19635525A1 (fr)
DK (1) DK0920441T3 (fr)
EA (1) EA001577B1 (fr)
EE (1) EE04021B1 (fr)
ES (1) ES2191857T3 (fr)
HU (1) HUP9903106A3 (fr)
IL (1) IL128601A (fr)
IS (1) IS4976A (fr)
NO (1) NO315655B1 (fr)
NZ (1) NZ334277A (fr)
PL (1) PL186309B1 (fr)
PT (1) PT920441E (fr)
SK (1) SK18899A3 (fr)
TR (1) TR199900432T2 (fr)
TW (1) TW552267B (fr)
UA (1) UA50792C2 (fr)
WO (1) WO1998007740A1 (fr)
ZA (1) ZA977482B (fr)

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US6054446A (en) 1997-12-24 2000-04-25 Sri International Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use
US6503896B1 (en) 1997-12-24 2003-01-07 Sri International Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use
DE19807791A1 (de) 1998-02-19 1999-08-26 Schering Ag Kombinationspräparat aus Östrogen und Antiöstrogen
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DE19906159A1 (de) * 1999-02-09 2000-08-10 Schering Ag 16-Hydroxyestratriene als selektiv wirksame Estrogene
WO2001012622A1 (fr) * 1999-08-18 2001-02-22 Schering Aktiengesellschaft Derives de piperidine et de pyrrolidine ayant une activite neuronale
GB0000313D0 (en) * 2000-01-10 2000-03-01 Astrazeneca Uk Ltd Formulation
DE10019171A1 (de) * 2000-04-07 2001-10-18 Schering Ag Zusammensetzungen zur Verwendung als Penetrationsverstärker in transdermalen Formulierungen für hoch lipophile Wirkstoffe
AU2006202187B2 (en) * 2001-11-27 2008-11-06 Bayer Schering Pharma Aktiengesellschaft 17alpah-alkyl-17beta-oxy-estratrienes and intermediate products for their production, uses thereof and pharmaceutical preparations
DE10159217A1 (de) * 2001-11-27 2003-06-05 Schering Ag 17alpha-Alkyl-17ß-oxy-estratriene und Zwischenprodukte zu deren Herstellung, Verwendung der 17alpha-Alkyl-17ß-oxy-estratriene zur Herstellung von Arzneimitteln sowie pharmazeutische Präparate
US20040242551A1 (en) * 2003-05-28 2004-12-02 Schering Ag Composition comprising antiprogestins and pure antiestrogens for prophylaxis and treatment of hormone-dependent diseases
JP2007506805A (ja) 2004-07-27 2007-03-22 シコール インコーポレイティド ７α−アルキル化された１９−ノルステロイドの調製方法
AU2006317486B9 (en) 2005-11-22 2011-08-04 Sumitomo Chemical Company, Limited Organic sulfur compounds and use thereof as arthropodicides
DE102007023614A1 (de) 2007-05-21 2008-11-27 Bayer Schering Pharma Aktiengesellschaft Nichtsteroidale Progesteronrezeptor-Modulatoren
DE102007049630A1 (de) 2007-10-11 2009-10-29 Bayer Schering Pharma Aktiengesellschaft Nichtsteroidale Progesteronrezeptor-Modulatoren
JP5298631B2 (ja) 2007-05-18 2013-09-25 住友化学株式会社 有機硫黄化合物及びその有害節足動物防除用途
JP2009001551A (ja) 2007-05-18 2009-01-08 Sumitomo Chemical Co Ltd 有機硫黄化合物及びその有害節足動物防除用途
TW200904329A (en) 2007-05-18 2009-02-01 Sumitomo Chemical Co Organic sulfur compound and its use for controlling harmful arthropod
DE102007032800A1 (de) 2007-07-10 2009-01-15 Bayer Schering Pharma Aktiengesellschaft Nichtsteroidale Progesteronrezeptor-Modulatoren
SG185311A1 (en) 2007-10-16 2012-11-29 Repros Therapeutics Inc Trans-clomiphene for metabolic syndrome
DE102007058747A1 (de) 2007-12-05 2009-06-10 Bayer Schering Pharma Aktiengesellschaft Nichtsteroidale Progesteronrezeptor-Modulatoren
EP2070941A1 (fr) 2007-12-14 2009-06-17 Bayer Schering Pharma Aktiengesellschaft Synthèse stéréosélective de régulateurs négatifs sélectifs du récepteur de l'estrogène
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DE102008057230A1 (de) * 2008-11-11 2010-05-12 Bayer Schering Pharma Aktiengesellschaft Synergistische pharmazeutische Kombination mit einem Estrogenrezeptorantagonisten und einem Progestin
JP5212350B2 (ja) 2008-12-24 2013-06-19 住友化学株式会社 含ハロゲン有機硫黄化合物およびその用途
EP2258375A1 (fr) 2009-06-04 2010-12-08 Bayer Schering Pharma Aktiengesellschaft 17B-alkyl-17alpha-oxy-estratriene
DE102009034366A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-methylenoxyalkylenaryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034367A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-benzyliden-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten
DE102009034362A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034368A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-acyloxyalkylenphenyl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034525A1 (de) 2009-07-21 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
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Also Published As

Publication number Publication date
ATE231882T1 (de) 2003-02-15
BG103185A (en) 1999-11-30
TW552267B (en) 2003-09-11
EE04021B1 (et) 2003-04-15
CA2263708A1 (fr) 1998-02-26
TR199900432T2 (xx) 1999-04-21
NO990793D0 (no) 1999-02-19
BR9711328A (pt) 1999-08-17
JP2001503024A (ja) 2001-03-06
ES2191857T3 (es) 2003-09-16
DE59709239D1 (de) 2003-03-06
EA199900210A1 (ru) 1999-08-26
IL128601A0 (en) 2000-01-31
HUP9903106A3 (en) 2000-05-29
NO990793L (no) 1999-04-20
NZ334277A (en) 2000-10-27
ZA977482B (en) 1998-02-23
EP0920441A1 (fr) 1999-06-09
CZ57999A3 (cs) 1999-08-11
DK0920441T3 (da) 2003-05-26
HUP9903106A2 (hu) 2000-03-28
CN1231670A (zh) 1999-10-13
AR009278A1 (es) 2000-04-12
SK18899A3 (en) 1999-08-06
PL331863A1 (en) 1999-08-16
EE9900075A (et) 1999-10-15
BG62972B1 (bg) 2000-12-29
UA50792C2 (uk) 2002-11-15
EP0920441B1 (fr) 2003-01-29
PL186309B1 (pl) 2003-12-31
AU728843B2 (en) 2001-01-18
DE19635525A1 (de) 1998-02-26
IS4976A (is) 1999-02-11
AU4552097A (en) 1998-03-06
EA001577B1 (ru) 2001-06-25
NO315655B1 (no) 2003-10-06
WO1998007740A1 (fr) 1998-02-26
PT920441E (pt) 2003-06-30
KR20000068261A (ko) 2000-11-25

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