IL134372A0 - Recombinant expression of insulin c-peptide - Google Patents

Recombinant expression of insulin c-peptide

Info

Publication number: IL134372A0
Authority: IL; Israel
Prior art keywords: insulin; peptide; recombinant expression; recombinant; expression
Prior art date: 1997-08-07

Application number

IL13437298A

Other languages

English (en)

Original Assignee

Creative Peptides Sweden Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-08-07

Filing date

1998-08-07

Publication date

2001-04-30

1998-08-07 Application filed by Creative Peptides Sweden Ab filed Critical Creative Peptides Sweden Ab

2001-04-30 Publication of IL134372A0 publication Critical patent/IL134372A0/xx

Links

VOUAQYXWVJDEQY-QENPJCQMSA-N 33017-11-7 Chemical compound OC(=O)CC[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)NCC(=O)NCC(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(O)=O)CCC1 VOUAQYXWVJDEQY-QENPJCQMSA-N 0.000 title 1
238000003259 recombinant expression Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/705—Fusion polypeptide containing domain for protein-protein interaction containing a protein-A fusion
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Zoology (AREA)
Biomedical Technology (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Biophysics (AREA)
Diabetes (AREA)
General Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Biotechnology (AREA)
Wood Science & Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Endocrinology (AREA)
Physics & Mathematics (AREA)
Toxicology (AREA)
Plant Pathology (AREA)
Microbiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Obesity (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Hematology (AREA)
Emergency Medicine (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

IL13437298A 1997-08-07 1998-08-07 Recombinant expression of insulin c-peptide IL134372A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9716790.2A GB9716790D0 (en)	1997-08-07	1997-08-07	Recombinant DNA molecules comprising multimeric copies of a gene sequence and expression thereof
PCT/GB1998/002382 WO1999007735A2 (en)	1997-08-07	1998-08-07	Recombinant expression of insulin c-peptide

Publications (1)

Publication Number	Publication Date
IL134372A0 true IL134372A0 (en)	2001-04-30

Family

ID=10817184

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL13437298A IL134372A0 (en)	1997-08-07	1998-08-07	Recombinant expression of insulin c-peptide

Country Status (21)

Country	Link
US (1)	US6558924B1 (is)
EP (1)	EP1001980A1 (is)
JP (1)	JP2001512745A (is)
KR (1)	KR20010022590A (is)
CN (1)	CN1268141A (is)
AU (1)	AU750685B2 (is)
BG (1)	BG104161A (is)
BR (1)	BR9811850A (is)
CA (1)	CA2297382A1 (is)
EA (1)	EA200000202A1 (is)
EE (1)	EE200000072A (is)
GB (1)	GB9716790D0 (is)
HU (1)	HUP0004626A1 (is)
IL (1)	IL134372A0 (is)
IS (1)	IS5368A (is)
NO (1)	NO20000575L (is)
NZ (1)	NZ502450A (is)
PL (1)	PL339085A1 (is)
SK (1)	SK1532000A3 (is)
TR (1)	TR200000288T2 (is)
WO (1)	WO1999007735A2 (is)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20040005669A1 (en) *	1997-08-07	2004-01-08	Stefan Stahl	Recombinant expression of insulin C-peptide
FR2810674A1 (fr) *	2000-06-22	2001-12-28	Pf Medicament	Construction modifiee en amont du codon d'initiation pour la surexpression de proteines recombinantes
FR2810675B1 (fr) *	2000-06-22	2002-09-27	Pf Medicament	Construction modifiee en aval du codon d'initiation pour la surexpression de proteines recombinantes
CA2431964C (en) *	2000-12-20	2013-09-10	F. Hoffmann-La Roche Ag	Conjugates of erythropoietin (pep) with polyethylene glycol (peg)
WO2003068934A2 (en) *	2002-02-14	2003-08-21	Rutter William J	Chimeric molecules for cleavage in a treated host
BR0316560A (pt)	2002-11-26	2005-10-04	Nobex Corp	Conjugado de composto natriurético, formulação farmacêutica, método de tratar uma condição, método de preparação do conjugado de composto natriurético, conjugado de peptìdeo pró-polinatriurético modificado, análogo de peptìdeo natriurético, análogo de hbnp, composto, e, método de preparar um composto
US20050026826A1 (en) *	2003-01-17	2005-02-03	Margarethe Hoenig	Feline proinsulin, insulin and constituent peptides
WO2004106525A1 (fr) *	2003-06-03	2004-12-09	Shanghai Centre Of Research & Development Of New Drugs	Proteine de fusion pouvant etre exprimee tres efficacement et son procede de production
CN1930188B (zh) *	2004-03-10	2012-01-11	克赖顿大学	雌激素受体和使用方法
NZ603399A (en)	2010-05-17	2014-09-26	Cebix Inc	Pegylated c-peptide
WO2013075117A2 (en)	2011-11-17	2013-05-23	John Wahren	Pegylated c-peptide
AU2013234860B2 (en) *	2012-03-19	2016-01-21	Madeleine Pharmaceuticals Pty Ltd	Method of producing a recombinant peptide
WO2016145389A1 (en)	2015-03-12	2016-09-15	Board Of Trustees Of Michigan State University	Compositions and methods for measuring c-peptide binding and diagnosing immune-mediated diseases
CN109705221B (zh) *	2018-12-27	2021-03-09	美康生物科技股份有限公司	C肽免疫原及其单克隆抗体对及该抗体对在c肽磁微粒化学发光免疫试剂中的应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5210872B2 (is)	1973-07-14	1977-03-26
GB2068971B (en)	1980-01-30	1983-06-08	Searle & Co	Recombinant dna techniques
CA1213537A (en)	1984-05-01	1986-11-04	Canadian Patents And Development Limited - Societe Canadienne Des Brevets Et D'exploitation Limitee	Polypeptide expression method
AU605291B2 (en)	1987-03-20	1991-01-10	Micromet Ag	Process for the purification of recombinant polypeptides
US5013653A (en)	1987-03-20	1991-05-07	Creative Biomolecules, Inc.	Product and process for introduction of a hinge region into a fusion protein to facilitate cleavage
SE501169C2 (sv)	1988-02-05	1994-11-28	Aake Nygren	Framställning av serumalbuminbindande fusionsproteiner vilka innehåller protein G-domäner
US5130236A (en)	1989-12-07	1992-07-14	Eli Lilly And Company	Process for producing des(64,65)-proinsulin
US5595887A (en)	1990-07-16	1997-01-21	Bionebraska, Inc.	Purification directed cloning of peptides using carbonic anhydrase as the affinity binding segment
GB9015825D0 (en)	1990-07-18	1990-09-05	Ciba Geigy Ag	In vitro processing of fusion proteins
JPH07108232B2 (ja)	1990-10-09	1995-11-22	エム・ディ・リサーチ株式会社	ペプチド又は蛋白質の製造方法
US5953418A (en)	1995-06-14	1999-09-14	David Hall	Providing selective data broadcast receiver addressability
WO1997023639A1 (en)	1995-12-22	1997-07-03	Toray Industries, Inc.	Process for producing biologically active fused proteins

1997
- 1997-08-07 GB GBGB9716790.2A patent/GB9716790D0/en active Pending
1998
- 1998-08-07 BR BR9811850-1A patent/BR9811850A/pt not_active Application Discontinuation
- 1998-08-07 SK SK153-2000A patent/SK1532000A3/sk unknown
- 1998-08-07 TR TR2000/00288T patent/TR200000288T2/xx unknown
- 1998-08-07 EP EP98937689A patent/EP1001980A1/en not_active Withdrawn
- 1998-08-07 EA EA200000202A patent/EA200000202A1/ru unknown
- 1998-08-07 NZ NZ502450A patent/NZ502450A/xx unknown
- 1998-08-07 CA CA002297382A patent/CA2297382A1/en not_active Abandoned
- 1998-08-07 WO PCT/GB1998/002382 patent/WO1999007735A2/en not_active Ceased
- 1998-08-07 JP JP2000506237A patent/JP2001512745A/ja active Pending
- 1998-08-07 HU HU0004626A patent/HUP0004626A1/hu unknown
- 1998-08-07 PL PL98339085A patent/PL339085A1/xx not_active Application Discontinuation
- 1998-08-07 US US09/485,286 patent/US6558924B1/en not_active Expired - Fee Related
- 1998-08-07 EE EEP200000072A patent/EE200000072A/xx unknown
- 1998-08-07 IL IL13437298A patent/IL134372A0/xx unknown
- 1998-08-07 KR KR1020007001182A patent/KR20010022590A/ko not_active Withdrawn
- 1998-08-07 CN CN98808075A patent/CN1268141A/zh active Pending
- 1998-08-07 AU AU86407/98A patent/AU750685B2/en not_active Ceased
2000
- 2000-02-01 IS IS5368A patent/IS5368A/is unknown
- 2000-02-04 NO NO20000575A patent/NO20000575L/no not_active Application Discontinuation
- 2000-02-17 BG BG104161A patent/BG104161A/xx unknown

Also Published As

Publication number	Publication date
AU750685B2 (en)	2002-07-25
HUP0004626A1 (hu)	2001-04-28
SK1532000A3 (en)	2000-09-12
PL339085A1 (en)	2000-12-04
NZ502450A (en)	2002-10-25
AU8640798A (en)	1999-03-01
WO1999007735A2 (en)	1999-02-18
BR9811850A (pt)	2000-08-08
GB9716790D0 (en)	1997-10-15
US6558924B1 (en)	2003-05-06
TR200000288T2 (tr)	2000-06-21
EE200000072A (et)	2000-10-16
EA200000202A1 (ru)	2001-04-23
BG104161A (en)	2000-12-29
NO20000575D0 (no)	2000-02-04
JP2001512745A (ja)	2001-08-28
IS5368A (is)	2000-02-01
KR20010022590A (ko)	2001-03-26
NO20000575L (no)	2000-04-04
WO1999007735A3 (en)	1999-04-29
CN1268141A (zh)	2000-09-27
EP1001980A1 (en)	2000-05-24
CA2297382A1 (en)	1999-02-18

Publication	Publication Date	Title
PL337324A1 (en)	2000-08-14	Stable insulin preparations
EP1039920A4 (en)	2003-05-28	INSULIN ANALOGS ACYLATED BY FATTY ACID
IL125006A0 (en)	1999-01-26	Novel insulin derivatives having a rapid onset of action
IL135029A0 (en)	2001-05-20	Prefilled ampoules and manufacture thereof
ATA101795A (de)	2001-06-15	Insulinanalogon-protamin-komplex
AU1306799A (en)	1999-05-31	Improved injector syringe
HUP9904596A3 (en)	2000-07-28	Analogs of parathyroid hormone
EP0688570A3 (de)	1996-04-03	Insulinspritze
AU3236895A (en)	1996-03-04	Aspb1 insulin analogs
HUP0000432A3 (en)	2000-10-30	Insulin c-peptides
AU6586298A (en)	1998-10-22	Glucagon-like peptide-1 analogs
IS5368A (is)	2000-02-01	Tjáning raðbrigða C-peptíðs insúlíns
SI0884053T1 (en)	2003-02-28	Stable insulin formulations
HUP0001477A3 (en)	2001-10-29	Calcitonin receptor-binding peptides
GB9714680D0 (en)	1997-09-17	Recombinant production of proteins
EP0999848A4 (en)	2003-03-05	CHIMEAN PROTEINS FOR TREATING DIABETES
GB9513967D0 (en)	1995-09-06	Insulin
GB9700789D0 (en)	1997-03-05	Syringe
HK1028050A (en)	2001-02-02	Recombinant expression of insulin c-peptide
IL135050A0 (en)	2001-05-20	Insulin-like polypeptide and uses therefor
GB9714681D0 (en)	1997-09-17	Recombinant production of proteins
TW364360U (en)	1999-07-11	Improvement on structure of syringe
GB9727105D0 (en)	1998-02-25	Hypodermic syringe
ZA975495B (en)	1999-02-24	Production of recombinant baculoviruses
GB9719796D0 (en)	1997-11-19	Medicament