IL142959A0 - Nitrogen containing heterobicycles as factor xa inhibitors - Google Patents

Nitrogen containing heterobicycles as factor xa inhibitors

Info

Publication number
IL142959A0
IL142959A0 IL14295999A IL14295999A IL142959A0 IL 142959 A0 IL142959 A0 IL 142959A0 IL 14295999 A IL14295999 A IL 14295999A IL 14295999 A IL14295999 A IL 14295999A IL 142959 A0 IL142959 A0 IL 142959A0
Authority
IL
Israel
Prior art keywords
inhibitors
factor
nitrogen containing
containing heterobicycles
heterobicycles
Prior art date
Application number
IL14295999A
Other languages
English (en)
Original Assignee
Du Pont Pharm Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26811284&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL142959(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Du Pont Pharm Co filed Critical Du Pont Pharm Co
Publication of IL142959A0 publication Critical patent/IL142959A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL14295999A 1998-12-23 1999-12-17 Nitrogen containing heterobicycles as factor xa inhibitors IL142959A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11362898P 1998-12-23 1998-12-23
US12763399P 1999-04-02 1999-04-02
PCT/US1999/030316 WO2000039131A1 (fr) 1998-12-23 1999-12-17 Heterobicycliques contenant de l'azote utilises comme inhibiteurs du facteur xa

Publications (1)

Publication Number Publication Date
IL142959A0 true IL142959A0 (en) 2002-04-21

Family

ID=26811284

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14295999A IL142959A0 (en) 1998-12-23 1999-12-17 Nitrogen containing heterobicycles as factor xa inhibitors
IL142959A IL142959A (en) 1998-12-23 2001-05-03 Nitrogen containing heterobicycles and pharmaceutical compositions comprising same

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL142959A IL142959A (en) 1998-12-23 2001-05-03 Nitrogen containing heterobicycles and pharmaceutical compositions comprising same

Country Status (26)

Country Link
US (2) US6413980B1 (fr)
EP (1) EP1140941B1 (fr)
JP (1) JP2002533465A (fr)
KR (1) KR100628407B1 (fr)
CN (1) CN100340559C (fr)
AR (1) AR024242A1 (fr)
AT (1) ATE280171T1 (fr)
AU (1) AU759711B2 (fr)
BR (1) BR9917080A (fr)
CA (1) CA2349330C (fr)
DE (1) DE69921358T2 (fr)
DK (1) DK1140941T3 (fr)
EA (1) EA004515B1 (fr)
ES (1) ES2232202T3 (fr)
HK (1) HK1052508B (fr)
HR (1) HRP990396A2 (fr)
IL (2) IL142959A0 (fr)
MX (1) MXPA01006502A (fr)
MY (1) MY138239A (fr)
NO (1) NO319816B1 (fr)
NZ (1) NZ511674A (fr)
PT (1) PT1140941E (fr)
SI (1) SI1140941T1 (fr)
TW (1) TWI225862B (fr)
WO (1) WO2000039131A1 (fr)
ZA (1) ZA200103795B (fr)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
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AU2001268712A1 (en) 2000-06-23 2002-01-08 Bristol-Myers Squibb Company 1 - (heteroaryl-phenyl) - condensed pyrazol derivatives as factor Xa inhibitors
US20040077605A1 (en) * 2001-06-20 2004-04-22 Salvati Mark E. Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
EP1854798A3 (fr) 2000-09-19 2007-11-28 Bristol-Myers Squibb Company Composés de succinimide hétérocyclique fondu et leurs analogies, modulateurs de la fonction de récepteur d'hormone nucléaire
US20040087548A1 (en) 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US6960595B2 (en) * 2001-03-23 2005-11-01 Bristol-Myers Squibb Pharma Company 5-6 to 5-7 Heterobicycles as factor Xa inhibitors
US6750225B2 (en) 2001-04-18 2004-06-15 Bristol-Myers Squibb Pharms Company 1,4,5,6-tetrahydropyrazolo-[3,4,-c]-pyridin-7-ones useful as factor Xa inhibitors
CA2441772A1 (fr) 2001-04-18 2002-10-31 Bristol-Myers Squibb Company 1,4,5,6-tetrahydropyrazolo-¬3,4-c|-pyridin-7-ones utilisees comme inhibiteurs du facteur xa
EP1414449A4 (fr) * 2001-05-22 2005-04-06 Bristol Myers Squibb Co Inhibiteurs bicycliques du facteur xa
TWI331526B (en) 2001-09-21 2010-10-11 Bristol Myers Squibb Pharma Co Lactam-containing compounds and derivatives thereof as factor xa inhibitors
EP1427415B1 (fr) 2001-09-21 2009-08-12 Brystol-Myers Squibb Company Composes contenant du lactame et leurs derives en tant qu'inhibiteurs du facteur xa
TW200302225A (en) 2001-12-04 2003-08-01 Bristol Myers Squibb Co Substituted amino methyl factor Xa inhibitors
WO2003048081A2 (fr) * 2001-12-04 2003-06-12 Bristol-Myers Squibb Company Glycinamides en tant qu'inhibiteurs du facteur xa
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EP1569912B1 (fr) 2002-12-03 2015-04-29 Pharmacyclics, Inc. Derives de 2-(2-hydroxybiphenyl-3-yl)-1h-benzoimidazole-5-carboxamidine utilises en tant qu'inhibiteurs du facteur viia
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CN104530029B (zh) * 2014-12-09 2017-04-12 广东东阳光药业有限公司 作为Xa因子抑制剂的杂环化合物及其使用方法和用途
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CN107235986B (zh) * 2017-05-27 2019-04-12 华南师范大学 一种合成氮氧杂桥联唑啉化合物的方法
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KR102128509B1 (ko) 2018-12-19 2020-07-01 한국과학기술연구원 말단 아민기에 아릴 또는 헤테로아릴기가 치환된 신규한 히드라존 유도체 및 이의 용도
US11667613B2 (en) 2019-09-26 2023-06-06 Novartis Ag Antiviral pyrazolopyridinone compounds
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Also Published As

Publication number Publication date
EA200100688A1 (ru) 2001-12-24
AR024242A1 (es) 2002-09-25
MXPA01006502A (es) 2002-04-08
TWI225862B (en) 2005-01-01
IL142959A (en) 2010-05-31
EP1140941A1 (fr) 2001-10-10
HK1052508A1 (zh) 2003-09-19
US20030004167A1 (en) 2003-01-02
BR9917080A (pt) 2002-03-12
JP2002533465A (ja) 2002-10-08
NZ511674A (en) 2003-11-28
ES2232202T3 (es) 2005-05-16
NO319816B1 (no) 2005-09-19
CA2349330C (fr) 2009-09-29
KR100628407B1 (ko) 2006-09-26
DK1140941T3 (da) 2005-02-14
NO20013072D0 (no) 2001-06-20
KR20010092754A (ko) 2001-10-26
MY138239A (en) 2009-05-29
SI1140941T1 (en) 2005-04-30
DE69921358D1 (de) 2004-11-25
AU759711B2 (en) 2003-04-17
US6413980B1 (en) 2002-07-02
EP1140941B1 (fr) 2004-10-20
US6673810B2 (en) 2004-01-06
CN100340559C (zh) 2007-10-03
HRP990396A2 (en) 2000-08-31
DE69921358T2 (de) 2006-03-09
CN1391575A (zh) 2003-01-15
ATE280171T1 (de) 2004-11-15
NO20013072L (no) 2001-06-20
EA004515B1 (ru) 2004-04-29
CA2349330A1 (fr) 2000-07-06
HK1052508B (zh) 2008-08-01
ZA200103795B (en) 2002-08-12
AU2371700A (en) 2000-07-31
WO2000039131A1 (fr) 2000-07-06
PT1140941E (pt) 2005-02-28

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