IL145012A0 - Fluorine substituted triarylmethane derivatives and pharmaceutical compositions containing the same - Google Patents

Fluorine substituted triarylmethane derivatives and pharmaceutical compositions containing the same

Info

Publication number
IL145012A0
IL145012A0 IL14501200A IL14501200A IL145012A0 IL 145012 A0 IL145012 A0 IL 145012A0 IL 14501200 A IL14501200 A IL 14501200A IL 14501200 A IL14501200 A IL 14501200A IL 145012 A0 IL145012 A0 IL 145012A0
Authority
IL
Israel
Prior art keywords
same
pharmaceutical compositions
compositions containing
fluorine substituted
triarylmethane derivatives
Prior art date
Application number
IL14501200A
Other languages
English (en)
Original Assignee
Icagen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Icagen Inc filed Critical Icagen Inc
Publication of IL145012A0 publication Critical patent/IL145012A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/11—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/65—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL14501200A 1999-02-23 2000-02-10 Fluorine substituted triarylmethane derivatives and pharmaceutical compositions containing the same IL145012A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13551199P 1999-02-23 1999-02-23
US09/386,601 US6288122B1 (en) 1999-02-23 1999-08-31 Gardos channel antagonists
PCT/US2000/003663 WO2000050026A1 (en) 1999-02-23 2000-02-10 Gardos channel antagonists

Publications (1)

Publication Number Publication Date
IL145012A0 true IL145012A0 (en) 2002-06-30

Family

ID=26833406

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14501200A IL145012A0 (en) 1999-02-23 2000-02-10 Fluorine substituted triarylmethane derivatives and pharmaceutical compositions containing the same
IL145012A IL145012A (en) 1999-02-23 2001-08-21 History of trirylamate converted with fluoride and pharmaceutical preparations containing them

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL145012A IL145012A (en) 1999-02-23 2001-08-21 History of trirylamate converted with fluoride and pharmaceutical preparations containing them

Country Status (16)

Country Link
US (1) US6288122B1 (2)
EP (1) EP1158971B1 (2)
JP (2) JP4038337B2 (2)
KR (1) KR100705726B1 (2)
CN (1) CN1193748C (2)
AP (1) AP1465A (2)
AT (1) ATE370728T1 (2)
AU (1) AU762039B2 (2)
BR (1) BR0008416A (2)
CA (1) CA2371857C (2)
DE (1) DE60036093T2 (2)
ES (1) ES2291191T3 (2)
HK (1) HK1045262B (2)
IL (2) IL145012A0 (2)
OA (1) OA11838A (2)
WO (1) WO2000050026A1 (2)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003004010A1 (en) * 2001-07-06 2003-01-16 Poseidon Pharmaceuticals A/S Carbonylamino derivatives useful for obtaining immune regulation
EP1465863B1 (en) 2002-01-04 2008-07-09 NeuroSearch A/S Potassium channel modulators
AU2003217810C9 (en) * 2002-02-28 2008-06-12 Icagen, Inc. Methods for treating diseases related to intraocular pressure
WO2005003143A1 (en) * 2003-07-03 2005-01-13 Poseidon Pharmaceuticals A/S Novel potassium channel modulators
WO2005003094A1 (en) * 2003-07-03 2005-01-13 Poseidon Pharmaceuticals A/S Diarylmethyl derivatives as potassium channel modulators
WO2006084031A1 (en) * 2005-02-01 2006-08-10 Icagen, Inc. Imines as ion channel modulators
US20100056637A1 (en) * 2005-12-20 2010-03-04 Icagen, Inc. Treatment methods using triaryl methane compounds
EP1968563A4 (en) * 2005-12-20 2010-05-19 Icagen Inc TREATMENT METHODS USING TRIARYLMETHANE COMPOUNDS
PT2192896E (pt) 2007-08-24 2011-04-04 Neurosearch As Derivados de carbonilamino úteis para o tratamento de doença inflamatória intestinal
US20090076157A1 (en) * 2007-09-15 2009-03-19 Protia, Llc Deuterium-enriched senicapoc
EA023596B1 (ru) 2008-04-09 2016-06-30 Сирус Корпорейшн Способы обработки композиции эритроцитов для инактивации патогена
EP2358750B1 (en) 2008-11-10 2017-01-11 Boehringer Ingelheim International GmbH Compositions and methods for modulating cell-cell fusion via intermediate-conductance calcium-activated potassium channels
WO2016134353A1 (en) * 2015-02-20 2016-08-25 Children's Medical Center Corporation Methods for treating malaria using potassium channel inhibitors
EP3106155A1 (en) 2015-06-15 2016-12-21 Universite d'Aix Marseille Treatment and diagnosis of hereditary xerocytosis
AU2017350760B2 (en) * 2016-10-25 2022-03-31 Paracelsus Neuroscience I, LIc Use of senicapoc for treatment of neuropathic pain
WO2018162426A1 (en) 2017-03-06 2018-09-13 INSERM (Institut National de la Santé et de la Recherche Médicale) Treatment and diagnosis of hereditary xerocytosis
WO2020198939A1 (zh) * 2019-03-29 2020-10-08 深圳仁泰医药科技有限公司 2,2-双(4-氟苯基)-2-苯乙酰胺的晶型a及其制备方法和应用
US12186286B2 (en) * 2019-07-29 2025-01-07 Paracelsus Neuroscience Llc Use of senicapoc for treatment of stroke
CN115943138A (zh) * 2020-07-14 2023-04-07 阿迪玛生物有限责任公司 包含gardos通道拮抗剂的组合物及其用途
CA3201648A1 (en) * 2020-12-11 2022-06-16 Robin VAN BRUGGEN Treatment and prevention of anaemia of inflammation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5273992A (en) 1992-11-02 1993-12-28 Beth Israel Hospital Assoc. Inc. Method for reducing sickle erythrocyte dehydration and delaying the occurrence of erythrocyte sickling in-situ
WO1997034589A1 (en) 1996-03-20 1997-09-25 President And Fellows Of Harvard College Triaryl methane compounds for sickle cell disease

Also Published As

Publication number Publication date
JP4038337B2 (ja) 2008-01-23
DE60036093T2 (de) 2008-05-15
KR100705726B1 (ko) 2007-04-11
AP1465A (en) 2005-09-22
AU2880700A (en) 2000-09-14
JP2007262075A (ja) 2007-10-11
AU762039B2 (en) 2003-06-19
EP1158971A4 (en) 2003-04-16
IL145012A (en) 2006-12-10
AP2001002268A0 (en) 2001-09-30
US6288122B1 (en) 2001-09-11
BR0008416A (pt) 2002-01-29
CA2371857A1 (en) 2000-08-31
OA11838A (en) 2005-08-22
WO2000050026A1 (en) 2000-08-31
EP1158971A1 (en) 2001-12-05
CN1344158A (zh) 2002-04-10
CN1193748C (zh) 2005-03-23
ATE370728T1 (de) 2007-09-15
HK1045262A1 (en) 2002-11-22
DE60036093D1 (de) 2007-10-04
ES2291191T3 (es) 2008-03-01
HK1045262B (zh) 2005-07-29
EP1158971B1 (en) 2007-08-22
KR20020002393A (ko) 2002-01-09
CA2371857C (en) 2008-07-29
JP2002537331A (ja) 2002-11-05

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed