IL146484A0 - Microgranules insoluble in gastric fluid, method for obtaining same and pharmaceutical preparations - Google Patents

Microgranules insoluble in gastric fluid, method for obtaining same and pharmaceutical preparations

Info

Publication number
IL146484A0
IL146484A0 IL14648400A IL14648400A IL146484A0 IL 146484 A0 IL146484 A0 IL 146484A0 IL 14648400 A IL14648400 A IL 14648400A IL 14648400 A IL14648400 A IL 14648400A IL 146484 A0 IL146484 A0 IL 146484A0
Authority
IL
Israel
Prior art keywords
pharmaceutical preparations
gastric fluid
obtaining same
microgranules
insoluble
Prior art date
Application number
IL14648400A
Other languages
English (en)
Original Assignee
Prod Ethiques Ethypharm Sa Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9545866&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL146484(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Prod Ethiques Ethypharm Sa Lab filed Critical Prod Ethiques Ethypharm Sa Lab
Publication of IL146484A0 publication Critical patent/IL146484A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL14648400A 1999-05-21 2000-05-19 Microgranules insoluble in gastric fluid, method for obtaining same and pharmaceutical preparations IL146484A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9906479A FR2793688B1 (fr) 1999-05-21 1999-05-21 Microgranules gastroproteges, procede d'obtention et preparations pharmaceutiques
PCT/FR2000/001367 WO2000071121A1 (fr) 1999-05-21 2000-05-19 Microgranules gastroproteges, procede d'obtention et preparations pharmaceutiques

Publications (1)

Publication Number Publication Date
IL146484A0 true IL146484A0 (en) 2002-07-25

Family

ID=9545866

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14648400A IL146484A0 (en) 1999-05-21 2000-05-19 Microgranules insoluble in gastric fluid, method for obtaining same and pharmaceutical preparations
IL146484A IL146484A (en) 1999-05-21 2001-11-13 Insoluble microgranols in gastric fluid, method of manufacture and pharmaceutical preparations

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL146484A IL146484A (en) 1999-05-21 2001-11-13 Insoluble microgranols in gastric fluid, method of manufacture and pharmaceutical preparations

Country Status (35)

Country Link
US (1) US8409612B1 (de)
EP (1) EP1178799B1 (de)
JP (2) JP5344781B2 (de)
KR (1) KR100603915B1 (de)
CN (1) CN1243546C (de)
AR (1) AR024036A1 (de)
AT (1) ATE247960T1 (de)
AU (1) AU771759B2 (de)
BG (1) BG65415B1 (de)
BR (1) BR0010832A (de)
CA (1) CA2373972C (de)
CZ (1) CZ302946B6 (de)
DE (1) DE60004815T2 (de)
DK (1) DK1178799T3 (de)
EA (1) EA003943B1 (de)
EE (1) EE04902B1 (de)
ES (1) ES2204598T3 (de)
FR (1) FR2793688B1 (de)
GE (1) GEP20053580B (de)
HK (1) HK1042851B (de)
HR (1) HRP20010940B1 (de)
HU (1) HU227590B1 (de)
IL (2) IL146484A0 (de)
IS (1) IS2160B (de)
MX (1) MXPA01011973A (de)
NO (1) NO331643B1 (de)
PL (1) PL198355B1 (de)
PT (1) PT1178799E (de)
RS (1) RS50241B (de)
SI (1) SI1178799T1 (de)
SK (1) SK287605B6 (de)
TR (1) TR200103325T2 (de)
UA (1) UA72522C2 (de)
WO (1) WO2000071121A1 (de)
ZA (1) ZA200109472B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2821745B1 (fr) * 2001-03-09 2004-07-02 Ethypharm Lab Prod Ethiques Granules et granules enrobes au gout masque
FR2822704B1 (fr) * 2001-03-29 2005-02-18 Chiesi Sa Sels de cetoacides et d'acides amines gastroresistants et leur utilisation pour la preparation de medicaments
FR2845289B1 (fr) * 2002-10-04 2004-12-03 Ethypharm Sa Spheroides, procede de preparation et compositions pharmaceutiques.
ES2234393B2 (es) * 2003-04-29 2006-09-01 Laboratorios Belmac, S.A. "formulaciones de pelets de compuestos bencimidazolicos antiulcerosos y labiles al acido".
US8980894B2 (en) 2004-03-25 2015-03-17 Boehringer Ingelheim Vetmedica Gmbh Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure
EP1579862A1 (de) 2004-03-25 2005-09-28 Boehringer Ingelheim Vetmedica Gmbh Verwendung von PDE III Ihibitoren zur Reduktion der Herzgrösse in an Herzversagen leidenden Säugern
EP1920785A1 (de) 2006-11-07 2008-05-14 Boehringer Ingelheim Vetmedica Gmbh Pimobendan-Cyclodextrin Komplex enthaltendes flüssiges Präparat
WO2013135852A1 (en) 2012-03-15 2013-09-19 Boehringer Ingelheim Vetmedica Gmbh Pharmaceutical tablet formulation for the veterinary medical sector, method of production and use thereof
PL3021832T3 (pl) 2013-07-19 2021-08-23 Boehringer Ingelheim Vetmedica Gmbh Konserwowana ciekła wodna kompozycja farmaceutyczna zawierająca eteryfikowane pochodne cyklodekstryny
PL3106150T3 (pl) * 2013-12-04 2022-01-03 Boehringer Ingelheim Vetmedica Gmbh Ulepszone kompozycje farmaceutyczne pimobendanu
WO2016174664A1 (en) 2015-04-29 2016-11-03 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US10537570B2 (en) 2016-04-06 2020-01-21 Boehringer Ingelheim Vetmedica Gmbh Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4153677A (en) * 1978-05-18 1979-05-08 Sterling Drug Inc. Controlled-release composition
DK151608C (da) * 1982-08-13 1988-06-20 Benzon As Alfred Fremgangsmaade til fremstilling af et farmaceutisk peroralt polydepotpraeparat med kontrolleret afgivelse
GB8809421D0 (en) * 1988-04-21 1988-05-25 Fordonal Sa Antacid compositions with prolonged gastric residence time
JPH0768125B2 (ja) 1988-05-18 1995-07-26 エーザイ株式会社 酸不安定化合物の内服用製剤
US5654009A (en) * 1991-03-25 1997-08-05 Fujisawa Pharmaceutical Co., Ltd. Delayed action preparation
EP0520119A1 (de) * 1991-06-17 1992-12-30 Spirig Ag Pharmazeutische Präparate Neue orale Diclofenaczubereitung
US5681585A (en) * 1991-12-24 1997-10-28 Euro-Celtique, S.A. Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer
FR2692146B1 (fr) * 1992-06-16 1995-06-02 Ethypharm Sa Compositions stables de microgranules d'omeprazole gastro-protégés et leur procédé d'obtention.
JPH09510465A (ja) * 1994-03-18 1997-10-21 シュミット，アルフレート ヘリコバクター・ピロリ（Ｈｐ）関連症候群および感染性疾患における局所抗菌治療および／または予防および治療へのジメチコンの使用
SE9402431D0 (sv) * 1994-07-08 1994-07-08 Astra Ab New tablet formulation
GB2290965A (en) 1994-07-11 1996-01-17 Therapicon Srl Multiple layer capsules for drugs
AU3533395A (en) * 1994-09-30 1996-04-26 Takeda Chemical Industries Ltd. Oral sustained-release preparation
ES2094694B1 (es) * 1995-02-01 1997-12-16 Esteve Quimica Sa Nueva formulacion farmaceuticamente estable de un compuesto de bencimidazol y su proceso de obtencion.
SE9500422D0 (sv) * 1995-02-06 1995-02-06 Astra Ab New oral pharmaceutical dosage forms
US5708017A (en) 1995-04-04 1998-01-13 Merck & Co., Inc. Stable, ready-to-use pharmaceutical paste composition containing proton pump inhibitors
JP3198337B2 (ja) 1995-09-21 2001-08-13 ファーマ パス エルエルシー 酸不安定性ベンゾイミダゾールを含有する新規組成物及びその製造方法
JPH1029937A (ja) * 1996-05-15 1998-02-03 Kobayashi Seiyaku Kogyo Kk メフェナム酸水溶液製剤
ATE271379T1 (de) 1996-11-06 2004-08-15 Wockhardt Europ Ltd System zur verzögerten freisetzung säurelabiler substanzen
GB9710800D0 (en) * 1997-05-23 1997-07-23 Cipla Limited Pharmaceutical composition and method of preparing it
ES2137862B1 (es) * 1997-07-31 2000-09-16 Intexim S A Preparacion farmaceutica oral que comprende un compuesto de actividad antiulcerosa y procedimiento para su obtencion.
US6013280A (en) * 1997-10-07 2000-01-11 Fuisz Technologies Ltd. Immediate release dosage forms containing microspheres
JP4612184B2 (ja) * 1997-12-08 2011-01-12 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 酸不安定な活性化合物を含有する新規の投与形
SE9704870D0 (sv) 1997-12-22 1997-12-22 Astra Ab New pharmaceutical formulation I
SE9704869D0 (sv) 1997-12-22 1997-12-22 Astra Ab New pharmaceutical formulaton II
FR2774288B1 (fr) * 1998-01-30 2001-09-07 Ethypharm Sa Microgranules d'omeprazole gastroproteges, procede d'obtention et preparations pharmaceutiques

Also Published As

Publication number Publication date
PL198355B1 (pl) 2008-06-30
JP2011157390A (ja) 2011-08-18
EA003943B1 (ru) 2003-10-30
JP5344781B2 (ja) 2013-11-20
EA200101221A1 (ru) 2002-04-25
ZA200109472B (en) 2002-08-07
NO20015480D0 (no) 2001-11-08
AU771759B2 (en) 2004-04-01
HU227590B1 (hu) 2011-09-28
DK1178799T3 (da) 2003-12-22
RS50241B (sr) 2009-07-15
HUP0201304A2 (en) 2002-08-28
FR2793688A1 (fr) 2000-11-24
IL146484A (en) 2006-04-10
WO2000071121A1 (fr) 2000-11-30
CZ302946B6 (cs) 2012-01-25
EP1178799B1 (de) 2003-08-27
AU4765300A (en) 2000-12-12
BG106102A (en) 2002-07-31
AR024036A1 (es) 2002-09-04
KR100603915B1 (ko) 2006-07-24
SK16322001A3 (sk) 2002-05-09
WO2000071121A9 (fr) 2002-05-23
BR0010832A (pt) 2002-03-05
TR200103325T2 (tr) 2002-05-21
CA2373972C (fr) 2011-07-12
CZ20014155A3 (cs) 2002-04-17
SI1178799T1 (en) 2003-12-31
ES2204598T3 (es) 2004-05-01
GEP20053580B (en) 2005-07-25
CN1243546C (zh) 2006-03-01
EE04902B1 (et) 2007-10-15
JP2003500358A (ja) 2003-01-07
KR20020011990A (ko) 2002-02-09
EE200100615A (et) 2003-02-17
BG65415B1 (bg) 2008-07-31
IS2160B (is) 2006-11-15
US8409612B1 (en) 2013-04-02
HK1042851B (zh) 2004-01-30
HRP20010940B1 (en) 2004-10-31
NO331643B1 (no) 2012-02-13
YU82301A (sh) 2004-07-15
SK287605B6 (sk) 2011-03-04
PL351658A1 (en) 2003-05-19
HUP0201304A3 (en) 2007-11-28
MXPA01011973A (es) 2002-05-06
EP1178799A1 (de) 2002-02-13
DE60004815D1 (de) 2003-10-02
IS6151A (is) 2001-11-08
CN1351494A (zh) 2002-05-29
PT1178799E (pt) 2004-01-30
DE60004815T2 (de) 2004-06-17
FR2793688B1 (fr) 2003-06-13
ATE247960T1 (de) 2003-09-15
HK1042851A1 (en) 2002-08-30
CA2373972A1 (fr) 2000-11-30
UA72522C2 (en) 2005-03-15
HRP20010940A2 (en) 2003-02-28
NO20015480L (no) 2002-01-10

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed