IL148008A0 - Conditional immortalisation of cells - Google Patents

Conditional immortalisation of cells

Info

Publication number
IL148008A0
IL148008A0 IL14800800A IL14800800A IL148008A0 IL 148008 A0 IL148008 A0 IL 148008A0 IL 14800800 A IL14800800 A IL 14800800A IL 14800800 A IL14800800 A IL 14800800A IL 148008 A0 IL148008 A0 IL 148008A0
Authority
IL
Israel
Prior art keywords
cells
recombinant
conditional immortalisation
immortalisation
conditional
Prior art date
Application number
IL14800800A
Other languages
English (en)
Original Assignee
Reneuron Ltd
Ludwig Inst For Cancer Res Imp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reneuron Ltd, Ludwig Inst For Cancer Res Imp filed Critical Reneuron Ltd
Publication of IL148008A0 publication Critical patent/IL148008A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/027—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL14800800A 1999-09-17 2000-09-18 Conditional immortalisation of cells IL148008A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP99307405 1999-09-17
US09/663,537 US6399384B1 (en) 1999-09-17 2000-09-15 Conditional immortalization of cells
PCT/GB2000/003588 WO2001021790A1 (en) 1999-09-17 2000-09-18 Conditional immortalisation of cells

Publications (1)

Publication Number Publication Date
IL148008A0 true IL148008A0 (en) 2002-09-12

Family

ID=26153574

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14800800A IL148008A0 (en) 1999-09-17 2000-09-18 Conditional immortalisation of cells

Country Status (11)

Country Link
US (1) US6399384B1 (de)
EP (1) EP1212420B1 (de)
JP (1) JP2003510046A (de)
CN (1) CN1373804A (de)
AT (1) ATE297987T1 (de)
AU (1) AU757816B2 (de)
CA (1) CA2383253A1 (de)
DE (1) DE60020855T2 (de)
ES (1) ES2241652T3 (de)
IL (1) IL148008A0 (de)
WO (1) WO2001021790A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9518606D0 (en) * 1995-09-12 1995-11-15 Inst Of Psychiatry Neural transplantation
GB9907243D0 (en) * 1999-03-29 1999-05-26 Reneuron Ltd Therapy
GB0005856D0 (en) * 2000-03-10 2000-05-03 Reneuron Ltd Genetic constructs
DE10019195B4 (de) * 2000-04-17 2006-03-09 Heart Biosystems Gmbh Reversible Immortalisierung
US20050074747A1 (en) * 2000-09-08 2005-04-07 Wadih Arap Biopanning and rapid analysis of selective interactive ligands (brasil)
US20040170955A1 (en) 2000-09-08 2004-09-02 Wadih Arap Human and mouse targeting peptides identified by phage display
US7420030B2 (en) * 2000-09-08 2008-09-02 The Board Of Regents Of The University Of Texas System Aminopeptidase A (APA) targeting peptides for the treatment of cancer
US7452964B2 (en) 2001-09-07 2008-11-18 Board Of Regents, The University Of Texas System Compositions and methods of use of targeting peptides against placenta and adipose tissues
EP1207196A1 (de) * 2000-10-27 2002-05-22 Societe Des Produits Nestle S.A. Immortalisierte pre-osteoblasten und verfahren zur deren herstellung
CA2454357A1 (en) * 2001-07-18 2003-01-30 Wadih Arap An anti-angiogenic state in mice and humans with retinal photoreceptor cell degeneration
US7671010B2 (en) * 2002-08-30 2010-03-02 The Board Of Regents Of The University Of Texas System Compositions and methods of use of targeting peptides for diagnosis and therapy of human cancer
US8507445B2 (en) * 2001-09-07 2013-08-13 Board Of Regents, The University Of Texas System Compositions and methods of use of targeting peptides for diagnosis and therapy of human cancer
US20040048243A1 (en) * 2001-09-07 2004-03-11 Wadih Arap Methods and compositions for in vitro targeting
GB0125773D0 (en) * 2001-10-26 2001-12-19 Reneuron Ltd Constructs
JPWO2003038076A1 (ja) * 2001-10-31 2005-02-24 株式会社レノメディクス研究所 不死化間葉系細胞及びその利用
DE60334533D1 (de) * 2002-03-15 2010-11-25 Univ Duke Gewebe-engineering
BRPI0409383A (pt) * 2003-04-14 2006-04-18 Univ Texas métodos para produção livre de hibridoma ex vivo de anticorpos policlonais e monoclonais e geração de populações de célula imortalizada
JP4423428B2 (ja) * 2003-09-12 2010-03-03 リニューロン・リミテッド 細胞療法
US20050193432A1 (en) * 2003-11-18 2005-09-01 Whitehead Institute For Biomedical Research Xenograft model of functional normal and malignant human breast tissues in rodents and methods thereof
DE602005002430T2 (de) * 2004-09-30 2008-06-19 Reneuron Ltd., Guildford Zelllinie
US20090298095A1 (en) 2005-04-15 2009-12-03 The John Hopkins University Immortalization of cells including neuronal cells
ATE513034T1 (de) * 2005-12-16 2011-07-15 Ribovax Biotechnologies Sa Verfahren zur gewinnung immortalisierter antikörpersezernierender zellen
GB0822246D0 (en) 2008-12-05 2009-01-14 Reneuron Ltd Composition
GB0902034D0 (en) 2009-02-06 2009-03-11 Reneuron Ltd Method
EP2380905A1 (de) 2010-04-19 2011-10-26 Thrombotargets Europe, S.L. Phospholipidangereicherte Vesikel mit Gewebefaktor mit blutstillenden Aktivitäten sowie Verwendungen davon
CN105176913A (zh) * 2015-09-23 2015-12-23 扬州大学 一种奶牛乳腺上皮细胞永生化方法
CA3123408A1 (en) * 2018-12-16 2020-06-25 Figene, Llc Therapeutic uses of gene edited fibroblasts
GB202005494D0 (en) 2020-04-15 2020-05-27 Reneuron Ltd Induced pluripotent cell comprising a contollable transgene for conditional immortalisation
CN116355834A (zh) * 2023-03-29 2023-06-30 复旦大学附属中山医院 一种小鼠肝星状细胞的永生化制备试剂、试剂盒及方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5270191A (en) * 1988-04-12 1993-12-14 Massachusetts Institute Of Technology Method for manipulation of the cell types of eukaryotes
US5766948A (en) 1993-01-06 1998-06-16 The Regents Of The University Of California Method for production of neuroblasts
EP0799315A2 (de) 1994-12-19 1997-10-08 Cold Spring Harbor Laboratory Telomerase protein-komponente
GB9518606D0 (en) 1995-09-12 1995-11-15 Inst Of Psychiatry Neural transplantation
EP0932686A2 (de) 1996-10-01 1999-08-04 Geron Corporation Telomerase reverse-transkriptase
WO1998037181A2 (en) 1997-02-20 1998-08-27 Whitehead Institute For Biomedical Research Telomerase catalytic subunit gene and encoded protein

Also Published As

Publication number Publication date
CN1373804A (zh) 2002-10-09
ES2241652T3 (es) 2005-11-01
AU757816B2 (en) 2003-03-06
EP1212420B1 (de) 2005-06-15
ATE297987T1 (de) 2005-07-15
DE60020855D1 (de) 2005-07-21
JP2003510046A (ja) 2003-03-18
AU7301500A (en) 2001-04-24
DE60020855T2 (de) 2006-05-04
US6399384B1 (en) 2002-06-04
WO2001021790A1 (en) 2001-03-29
EP1212420A1 (de) 2002-06-12
CA2383253A1 (en) 2001-03-29

Similar Documents

Publication Publication Date Title
IL148008A0 (en) Conditional immortalisation of cells
AU4221399A (en) Human cd45+ and/or fibroblast + mesenchymal stem cells
IL148060A0 (en) Compositions and methods for improved cell culture
ATE252113T1 (de) Verwendung von wnt polypeptiden
IL137946A0 (en) Intracardiac cell delivery and cell transplantation
EP0456640A4 (de) Genetisch erzeugte endothelzellen und deren verwendung.
IL144654A0 (en) Pancreatic progenitor cells, methods and uses related thereto
GB2392674B (en) Mesenchymal cells and osteoblasts from human embryonic stem cell
MXPA02004882A (es) Genes de desarrollo de la planta.
MXPA04005266A (es) Inmunocitocinas con selectividad modulada.
AU9582398A (en) Methods and devices for the long-term culture of hematopoietic progenitor cells
MXPA02003733A (es) Metodos para producir celulas progenitoras diferenciadas y celulas troncales embrionicas de lineas de descendencia defectivas.
EP1447443A4 (de) Immortalisierte mesenchymzellen und ihre verwendung
NZ516400A (en) Stable factor VIII compositions
ATE342275T1 (de) Vorübergehend-immortalisierte zellen zur verwendung in gentherapie
EP1137808A4 (de) Methode zur herstellung von rekombinanten zellen
AU2878600A (en) Polynucleotide encoding a polypeptide having heparanase activity and expression of same in genetically modified cells
AU1478000A (en) (in utero) transplantation of human mesenchymal stem cells
GB9825096D0 (en) Cells,culture methods and their uses
AU2002303277A1 (en) Artificial chromosomes that can shuttle between bacteria, yeast, and mammalian cells
WO2000066731A3 (en) Recombinant laminin 5
DE69903559D1 (de) Verwendung von neuen zelltod inducierenden mitteln im synergismus mit interferon
GB2379446A (en) Cells,culture methods and their uses
DE69737597D1 (de) Vektoren zur inhibierung von viralem und tumorwachstum
IL148493A0 (en) Recombinant adenovirus preparation and adenovirus banks

Legal Events

Date Code Title Description
KB Patent renewed