IL149598A0 - Placental human neurokinin b precursor - Google Patents
Placental human neurokinin b precursorInfo
- Publication number
- IL149598A0 IL149598A0 IL14959800A IL14959800A IL149598A0 IL 149598 A0 IL149598 A0 IL 149598A0 IL 14959800 A IL14959800 A IL 14959800A IL 14959800 A IL14959800 A IL 14959800A IL 149598 A0 IL149598 A0 IL 149598A0
- Authority
- IL
- Israel
- Prior art keywords
- precursor
- methods
- human neurokinin
- neurokinin
- placental human
- Prior art date
Links
- 239000002243 precursor Substances 0.000 title abstract 2
- 101500027535 Homo sapiens Neurokinin-B Proteins 0.000 title 1
- 230000003169 placental effect Effects 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- 206010070538 Gestational hypertension Diseases 0.000 abstract 1
- 201000005624 HELLP Syndrome Diseases 0.000 abstract 1
- NHXYSAFTNPANFK-HDMCBQFHSA-N Neurokinin B Chemical compound C([C@@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O)C(C)C)NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1N=CNC=1)NC(=O)[C@H](CCSC)NC(=O)[C@@H](N)CC(O)=O)C1=CC=CC=C1 NHXYSAFTNPANFK-HDMCBQFHSA-N 0.000 abstract 1
- 102000046798 Neurokinin B Human genes 0.000 abstract 1
- 101800002813 Neurokinin-B Proteins 0.000 abstract 1
- 208000005347 Pregnancy-Induced Hypertension Diseases 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000005259 measurement Methods 0.000 abstract 1
- 201000011461 pre-eclampsia Diseases 0.000 abstract 1
- 208000036335 preeclampsia/eclampsia 1 Diseases 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/046—Tachykinins, e.g. eledoisins, substance P; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2410/00—Assays, e.g. immunoassays or enzyme assays, involving peptides of less than 20 animo acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/36—Gynecology or obstetrics
- G01N2800/368—Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Reproductive Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Gynecology & Obstetrics (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Pregnancy & Childbirth (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9927125.6A GB9927125D0 (en) | 1999-11-16 | 1999-11-16 | Placental human neurokinin B precursor |
| PCT/GB2000/004315 WO2001036979A2 (en) | 1999-11-16 | 2000-11-10 | Placental human neurokinin b precursor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL149598A0 true IL149598A0 (en) | 2002-11-10 |
Family
ID=10864633
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL14959800A IL149598A0 (en) | 1999-11-16 | 2000-11-10 | Placental human neurokinin b precursor |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US7947458B1 (de) |
| EP (1) | EP1229965B1 (de) |
| JP (1) | JP4668501B2 (de) |
| CN (1) | CN1414871A (de) |
| AT (1) | ATE299739T1 (de) |
| AU (1) | AU778423B2 (de) |
| CA (1) | CA2391531A1 (de) |
| DE (1) | DE60021409T2 (de) |
| ES (1) | ES2244480T3 (de) |
| GB (1) | GB9927125D0 (de) |
| IL (1) | IL149598A0 (de) |
| NO (1) | NO330412B1 (de) |
| NZ (1) | NZ519283A (de) |
| WO (1) | WO2001036979A2 (de) |
| ZA (1) | ZA200203880B (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6919433B2 (en) | 1997-03-14 | 2005-07-19 | Human Genome Sciences, Inc. | Antibodies to protein HPMBQ91 |
| EP1333092A3 (de) * | 1997-03-14 | 2003-12-10 | Human Genome Sciences, Inc. | 28 menschlich sekretierte Proteine |
| US20240336565A1 (en) | 2021-07-02 | 2024-10-10 | Acer Therapeutics, Inc. | Solid forms of osanetant |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4665157A (en) | 1985-09-30 | 1987-05-12 | Mcneilab, Inc. | Peptide antagonists of neurokinin B |
| US4742156A (en) * | 1985-09-30 | 1988-05-03 | Mcneilab, Inc. | Peptide antagonists of neurokinin B and opthalmic solutions containing them |
| US5331089A (en) | 1988-03-25 | 1994-07-19 | Merck Sharpe & Dohme, Ltd. | Peptides useful as tachykinin agonists |
| US5079171A (en) * | 1988-09-15 | 1992-01-07 | Adeza Biomedical Corporation | Determining pregnancy induced hypertension and eclampsia by immunoassay of cellular fibronectin |
| ES2149767T5 (es) | 1991-09-20 | 2005-06-16 | Glaxo Group Limited | Nuevo uso medico para antagonistas de taquiquininas. |
| US5328927A (en) | 1992-03-03 | 1994-07-12 | Merck Sharpe & Dohme, Ltd. | Hetercyclic compounds, processes for their preparation and pharmaceutical compositions containing them |
| AU4713293A (en) | 1992-07-13 | 1994-01-31 | Merck Sharp & Dohme Limited | Heterocyclic amide derivatives as tachykinin derivatives |
| CA2140640A1 (en) | 1992-08-13 | 1994-03-03 | David C. Horwell | Tachykinin antagonists |
| US5922681A (en) * | 1992-09-14 | 1999-07-13 | Warner-Lambert Company | Endothelin antagonists |
| FR2696178B1 (fr) | 1992-09-30 | 1994-12-30 | Sanofi Elf | Amides basiques quaternaires, procédé pour leur préparation et compositions pharmaceutiques en contenant. |
| US5344830A (en) | 1992-12-10 | 1994-09-06 | Merck & Co., Inc. | N,N-diacylpiperazine tachykinin antagonists |
| US5543138A (en) * | 1994-03-10 | 1996-08-06 | Genetics Institute, Inc. | Methods of diagnosing and treating preeclampsia |
| FR2719311B1 (fr) * | 1994-03-18 | 1998-06-26 | Sanofi Sa | Composés antagonistes sélectifs du récepteur NK3 humain et leur utilisation comme médicaments et outils de diagnostic. |
| US5491140A (en) | 1994-06-30 | 1996-02-13 | Eli Lilly And Company | Naphthyl tachykinin receptor antagonists to treat physiological conditions |
| AU688072B2 (en) | 1994-07-12 | 1998-03-05 | Eli Lilly And Company | Heterocyclic tachykinin receptor antagonists |
| CA2154116A1 (en) | 1994-07-22 | 1996-01-23 | Philip Arthur Hipskind | 1-aryl-2-acetamidopentanone derivatives for use as tachykinin receptor antagonists |
| EP0912178A4 (de) * | 1996-05-24 | 2000-08-16 | Lilly Co Eli | Verfahren zur behandlung des bluthochdrucks |
| GB9618931D0 (en) * | 1996-09-11 | 1996-10-23 | Univ London | Inositol phosphoglycans for therapeutic use in pre-eclampsia and diabetes |
| US5846973A (en) | 1997-05-23 | 1998-12-08 | Eli Lilly And Company | Methods of treating pulmonary hypertension |
| US5985606A (en) * | 1997-06-19 | 1999-11-16 | Incyte Pharmaceuticals, Inc. | Human preprotachykinin B |
| CA2236489A1 (en) * | 1997-07-14 | 1999-01-14 | Human Genome Sciences | Novel compounds |
| EP0892053A3 (de) * | 1997-07-14 | 1999-12-29 | Smithkline Beecham Plc | Herstellung von rekombinantem HPMBQ91 Polypeptide und dessen Verwendungen |
| US6689566B1 (en) * | 1999-01-14 | 2004-02-10 | Scantibodies Laboratory, Inc. | Methods, kits, and antibodies for detecting parathyroid hormone |
-
1999
- 1999-11-16 GB GBGB9927125.6A patent/GB9927125D0/en not_active Ceased
-
2000
- 2000-11-10 WO PCT/GB2000/004315 patent/WO2001036979A2/en not_active Ceased
- 2000-11-10 AT AT00974680T patent/ATE299739T1/de not_active IP Right Cessation
- 2000-11-10 US US10/130,340 patent/US7947458B1/en not_active Expired - Fee Related
- 2000-11-10 CN CN00818115A patent/CN1414871A/zh active Pending
- 2000-11-10 EP EP00974680A patent/EP1229965B1/de not_active Expired - Lifetime
- 2000-11-10 DE DE60021409T patent/DE60021409T2/de not_active Expired - Lifetime
- 2000-11-10 JP JP2001538816A patent/JP4668501B2/ja not_active Expired - Fee Related
- 2000-11-10 CA CA002391531A patent/CA2391531A1/en not_active Abandoned
- 2000-11-10 NZ NZ519283A patent/NZ519283A/en not_active IP Right Cessation
- 2000-11-10 IL IL14959800A patent/IL149598A0/xx unknown
- 2000-11-10 AU AU12898/01A patent/AU778423B2/en not_active Ceased
- 2000-11-10 ES ES00974680T patent/ES2244480T3/es not_active Expired - Lifetime
-
2002
- 2002-05-14 NO NO20022276A patent/NO330412B1/no not_active IP Right Cessation
- 2002-05-15 ZA ZA200203880A patent/ZA200203880B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1229965A2 (de) | 2002-08-14 |
| ES2244480T3 (es) | 2005-12-16 |
| WO2001036979A3 (en) | 2002-05-02 |
| DE60021409T2 (de) | 2006-05-24 |
| ZA200203880B (en) | 2003-08-15 |
| NO20022276D0 (no) | 2002-05-14 |
| CA2391531A1 (en) | 2001-05-25 |
| AU778423B2 (en) | 2004-12-02 |
| WO2001036979A2 (en) | 2001-05-25 |
| EP1229965B1 (de) | 2005-07-20 |
| NO20022276L (no) | 2002-07-05 |
| DE60021409D1 (de) | 2005-08-25 |
| GB9927125D0 (en) | 2000-01-12 |
| ATE299739T1 (de) | 2005-08-15 |
| AU1289801A (en) | 2001-05-30 |
| CN1414871A (zh) | 2003-04-30 |
| JP2003515138A (ja) | 2003-04-22 |
| NZ519283A (en) | 2004-05-28 |
| NO330412B1 (no) | 2011-04-11 |
| US7947458B1 (en) | 2011-05-24 |
| JP4668501B2 (ja) | 2011-04-13 |
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