IL149890A0 - Tnt-alpha antagonist and lfa-1 antagonist for treating lfa-1 or tnf-alpha mediated - Google Patents
Tnt-alpha antagonist and lfa-1 antagonist for treating lfa-1 or tnf-alpha mediatedInfo
- Publication number
- IL149890A0 IL149890A0 IL14989000A IL14989000A IL149890A0 IL 149890 A0 IL149890 A0 IL 149890A0 IL 14989000 A IL14989000 A IL 14989000A IL 14989000 A IL14989000 A IL 14989000A IL 149890 A0 IL149890 A0 IL 149890A0
- Authority
- IL
- Israel
- Prior art keywords
- antagonist
- lfa
- alpha
- tnf
- treating
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
- C07K16/2845—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta2-subunit-containing molecules, e.g. CD11, CD18
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Neurosurgery (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Virology (AREA)
- Cardiology (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Psychology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Psychiatry (AREA)
- Biophysics (AREA)
- Physical Education & Sports Medicine (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17069699P | 1999-12-14 | 1999-12-14 | |
| PCT/US2000/033875 WO2001043773A1 (fr) | 1999-12-14 | 2000-12-14 | Antagoniste de tnf-alpha et antagoniste de lfa-1 destines a traiter les affections induites par lfa-1 ou tnf-alpha |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL149890A0 true IL149890A0 (en) | 2002-11-10 |
Family
ID=22620900
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL14989000A IL149890A0 (en) | 1999-12-14 | 2000-12-14 | Tnt-alpha antagonist and lfa-1 antagonist for treating lfa-1 or tnf-alpha mediated |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US20010031260A1 (fr) |
| EP (1) | EP1237575B1 (fr) |
| JP (1) | JP2003517022A (fr) |
| KR (1) | KR100567292B1 (fr) |
| CN (1) | CN1409639A (fr) |
| AT (1) | ATE403437T1 (fr) |
| AU (1) | AU768324B2 (fr) |
| CA (1) | CA2394862C (fr) |
| DE (1) | DE60039783D1 (fr) |
| DK (1) | DK1237575T3 (fr) |
| ES (1) | ES2311483T3 (fr) |
| IL (1) | IL149890A0 (fr) |
| NZ (1) | NZ519222A (fr) |
| PT (1) | PT1237575E (fr) |
| WO (1) | WO2001043773A1 (fr) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6867203B2 (en) | 1998-12-29 | 2005-03-15 | Abbott Laboratories | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds |
| AU2001287000A1 (en) * | 2000-09-01 | 2002-03-13 | The Center For Blood Research, Inc. | Modified polypeptides stabilized in a desired conformation and methods for producing same |
| EP1372720A4 (fr) * | 2001-03-02 | 2006-07-26 | Medimmune Inc | Prevention ou traitement de troubles inflammatoires ou auto-immuns par l'administration d'antagonistes de l'integrine alpha v beta 3 |
| GB0111497D0 (en) * | 2001-05-11 | 2001-07-04 | Medical Res Council | Therapeutic methods |
| EP3210624A1 (fr) * | 2002-02-27 | 2017-08-30 | Immunex Corporation | Composition tnfr-fc stabilisée comportant de l'arginine |
| PT1946776T (pt) | 2002-02-27 | 2017-03-17 | Immunex Corp | Composição de tnfr-fc estabilizada compreendendo arginina |
| US20040033228A1 (en) | 2002-08-16 | 2004-02-19 | Hans-Juergen Krause | Formulation of human antibodies for treating TNF-alpha associated disorders |
| CA2497977A1 (fr) * | 2002-09-20 | 2004-04-01 | Alcon, Inc. | Utilisation d'inhibiteurs de la synthese des cytokines dans le traitement des troubles associes a la keratoconjonctivite seche |
| DE60333228D1 (de) | 2002-12-02 | 2010-08-12 | Amgen Fremont Inc | Gegen den tumor nekrose faktor gerichtete antikörper und deren verwendungen |
| WO2005039502A2 (fr) * | 2003-10-24 | 2005-05-06 | Azopax Therapeutics Llc | Compositions a base de macromeres fondus |
| AU2004287875B2 (en) | 2003-11-05 | 2011-06-02 | Bausch + Lomb Ireland Limited | Modulators of cellular adhesion |
| US8697139B2 (en) | 2004-09-21 | 2014-04-15 | Frank M. Phillips | Method of intervertebral disc treatment using articular chondrocyte cells |
| US7871988B1 (en) * | 2005-01-04 | 2011-01-18 | Gp Medical, Inc. | Nanoparticles for protein drug delivery |
| CN102961746B (zh) | 2005-05-16 | 2016-06-15 | 艾伯维生物技术有限公司 | TNFα抑制剂治疗腐蚀性多关节炎的用途 |
| DK2444079T3 (en) * | 2005-05-17 | 2017-01-30 | Sarcode Bioscience Inc | Compositions and Methods for the Treatment of Eye Diseases |
| MX2007015476A (es) | 2005-06-14 | 2008-02-25 | Amgen Inc | Formulaciones de proteina autoamortiguadoras. |
| AU2006326870A1 (en) * | 2005-12-22 | 2007-06-28 | Apollo Life Sciences | Transdermal delivery of pharmaceutical agents |
| US9605064B2 (en) | 2006-04-10 | 2017-03-28 | Abbvie Biotechnology Ltd | Methods and compositions for treatment of skin disorders |
| EP2007426A4 (fr) | 2006-04-10 | 2010-06-16 | Abbott Biotech Ltd | Compositions destinées au traitement de la polyarthrite psoriasique et leurs applications |
| EP2171451A4 (fr) | 2007-06-11 | 2011-12-07 | Abbott Biotech Ltd | Procédés de traitement de l'arthrite idiopathique juvénile |
| ES2630406T3 (es) | 2007-10-19 | 2017-08-21 | Sarcode Bioscience Inc. | Composición y procedimientos para el tratamiento de la retinopatía diabética |
| WO2009128934A1 (fr) * | 2008-04-15 | 2009-10-22 | Sarcode Corporation | Antagonistes de lfa-1 topiques utilisés dans le traitement localisé de troubles de nature immunitaire |
| US8080562B2 (en) | 2008-04-15 | 2011-12-20 | Sarcode Bioscience Inc. | Crystalline pharmaceutical and methods of preparation and use thereof |
| EP2265124A4 (fr) * | 2008-04-15 | 2011-12-28 | Sarcode Bioscience Inc | Antagonistes de lfa-1 sous forme d'aérosol utilisés en traitement localisé de troubles de nature immunitaire |
| MY174699A (en) * | 2009-08-06 | 2020-05-08 | Anitox Corp | Water and feed preservative |
| US8378105B2 (en) * | 2009-10-21 | 2013-02-19 | Sarcode Bioscience Inc. | Crystalline pharmaceutical and methods of preparation and use thereof |
| US9849192B2 (en) | 2009-11-18 | 2017-12-26 | Rutgers, The State University Of New Jersey | Targeting tumor cells with chemotherapeutic agents conjugated to matriptase antibodies |
| CA2818237C (fr) | 2009-11-18 | 2021-05-18 | University Of Medicine And Dentistry Of New Jersey | Ciblage de cellules tumorales par des agents chimiotherapeutiques conjugues a des anticorps diriges contre la matriptase |
| HUE036334T2 (hu) * | 2010-08-27 | 2018-07-30 | Anitox Corp | Antimikrobális készítmény |
| WO2013059012A1 (fr) | 2011-10-20 | 2013-04-25 | Anitox Corporation | Préparations antimicrobiennes contenant de l'acide pélargonique |
| PL2785205T3 (pl) | 2011-11-30 | 2021-06-28 | Anitox Corporation | Przeciwbakteryjna mieszanina aldehydów, kwasów organicznych i estrów kwasów organicznych |
| CA2879982C (fr) | 2012-07-25 | 2020-09-01 | Sarcode Bioscience Inc. | Inhibiteur de lfa-1 et polymorphe de celui-ci |
| WO2014046631A1 (fr) | 2012-09-19 | 2014-03-27 | Tezcaner Aysen | Systèmes d'administration contrôlée de médicaments anti-tnfα |
| CA2887037A1 (fr) * | 2012-10-02 | 2014-04-10 | Rutgers, The State University Of New Jersey | Administration specifique de toxines conjuguees a des anticorps jusqu'a la matriptase activee |
| KR20170138426A (ko) * | 2015-03-13 | 2017-12-15 | 삼성바이오에피스 주식회사 | 항-tnf-알파 폴리펩티드 조성물 및 그 용도 |
| RU2613056C1 (ru) * | 2016-03-14 | 2017-03-15 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Южно-Уральский государственный медицинский университет" Министерства здравоохранения Российской Федерации (ГБОУ ВПО ЮУГМУ Минздрава России) | Способ прогнозирования развития увеита у детей с ювенильным идиопатическим артритом |
| JP7145374B2 (ja) | 2016-03-18 | 2022-10-03 | ラトガース ザ ステイト ユニバーシティー オブ ニュージャージー | インビボでの切断可能連結部分によって抗マトリプターゼ抗体にコンジュゲートされた化学療法剤を用いる腫瘍細胞の標的化 |
| AU2017345490B2 (en) | 2016-10-21 | 2022-07-07 | Amgen Inc. | Pharmaceutical formulations and methods of making the same |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5672347A (en) * | 1984-07-05 | 1997-09-30 | Genentech, Inc. | Tumor necrosis factor antagonists and their use |
| IL83878A (en) * | 1987-09-13 | 1995-07-31 | Yeda Res & Dev | Soluble protein corresponding to tnf inhibitory protein its preparation and pharmaceutical compositions containing it |
| US5336603A (en) * | 1987-10-02 | 1994-08-09 | Genentech, Inc. | CD4 adheson variants |
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-
2000
- 2000-12-14 DE DE60039783T patent/DE60039783D1/de not_active Expired - Lifetime
- 2000-12-14 KR KR1020027007537A patent/KR100567292B1/ko not_active Expired - Fee Related
- 2000-12-14 DK DK00986377T patent/DK1237575T3/da active
- 2000-12-14 IL IL14989000A patent/IL149890A0/xx unknown
- 2000-12-14 AT AT00986377T patent/ATE403437T1/de not_active IP Right Cessation
- 2000-12-14 JP JP2001544909A patent/JP2003517022A/ja active Pending
- 2000-12-14 NZ NZ519222A patent/NZ519222A/en not_active IP Right Cessation
- 2000-12-14 US US09/738,540 patent/US20010031260A1/en not_active Abandoned
- 2000-12-14 WO PCT/US2000/033875 patent/WO2001043773A1/fr not_active Ceased
- 2000-12-14 PT PT00986377T patent/PT1237575E/pt unknown
- 2000-12-14 ES ES00986377T patent/ES2311483T3/es not_active Expired - Lifetime
- 2000-12-14 EP EP00986377A patent/EP1237575B1/fr not_active Expired - Lifetime
- 2000-12-14 CN CN00817171A patent/CN1409639A/zh active Pending
- 2000-12-14 CA CA2394862A patent/CA2394862C/fr not_active Expired - Fee Related
- 2000-12-14 AU AU54397/01A patent/AU768324B2/en not_active Ceased
-
2005
- 2005-05-12 US US11/128,912 patent/US20050214291A1/en not_active Abandoned
-
2007
- 2007-07-26 US US11/828,977 patent/US20080031875A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2003517022A (ja) | 2003-05-20 |
| EP1237575B1 (fr) | 2008-08-06 |
| DK1237575T3 (da) | 2008-12-08 |
| US20050214291A1 (en) | 2005-09-29 |
| WO2001043773A1 (fr) | 2001-06-21 |
| CA2394862C (fr) | 2011-10-11 |
| DE60039783D1 (de) | 2008-09-18 |
| ES2311483T3 (es) | 2009-02-16 |
| EP1237575A1 (fr) | 2002-09-11 |
| CN1409639A (zh) | 2003-04-09 |
| KR20020068372A (ko) | 2002-08-27 |
| US20080031875A1 (en) | 2008-02-07 |
| ATE403437T1 (de) | 2008-08-15 |
| CA2394862A1 (fr) | 2001-06-21 |
| US20010031260A1 (en) | 2001-10-18 |
| PT1237575E (pt) | 2008-11-17 |
| NZ519222A (en) | 2004-04-30 |
| AU768324B2 (en) | 2003-12-11 |
| KR100567292B1 (ko) | 2006-04-04 |
| AU5439701A (en) | 2001-06-25 |
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