IL157148A0 - Method for purifying 20 (s) - camptothecin - Google Patents

Method for purifying 20 (s) - camptothecin

Info

Publication number
IL157148A0
IL157148A0 IL15714802A IL15714802A IL157148A0 IL 157148 A0 IL157148 A0 IL 157148A0 IL 15714802 A IL15714802 A IL 15714802A IL 15714802 A IL15714802 A IL 15714802A IL 157148 A0 IL157148 A0 IL 157148A0
Authority
IL
Israel
Prior art keywords
camptothecin
purifying
mixture
crystals
hydrogenating
Prior art date
Application number
IL15714802A
Other languages
English (en)
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of IL157148A0 publication Critical patent/IL157148A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IL15714802A 2001-02-15 2002-02-09 Method for purifying 20 (s) - camptothecin IL157148A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10106969A DE10106969C1 (de) 2001-02-15 2001-02-15 Verfahren zur Reinigung und zur Herstellung von 20(S)-Camptothecin
PCT/EP2002/001375 WO2002064597A2 (de) 2001-02-15 2002-02-09 Verfahren zur reinigung von 20(s)-camptothecin

Publications (1)

Publication Number Publication Date
IL157148A0 true IL157148A0 (en) 2004-02-08

Family

ID=7674093

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15714802A IL157148A0 (en) 2001-02-15 2002-02-09 Method for purifying 20 (s) - camptothecin
IL157148A IL157148A (en) 2001-02-15 2003-07-29 Method for purifying 20(s)-camptothecin

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL157148A IL157148A (en) 2001-02-15 2003-07-29 Method for purifying 20(s)-camptothecin

Country Status (26)

Country Link
EP (1) EP1362051B1 (sr)
JP (1) JP4467884B2 (sr)
KR (1) KR100813087B1 (sr)
CN (1) CN1228340C (sr)
AT (1) ATE301124T1 (sr)
AU (1) AU2002244711B2 (sr)
BG (1) BG108064A (sr)
BR (1) BR0207261A (sr)
CA (1) CA2435372C (sr)
CZ (1) CZ300671B6 (sr)
DE (2) DE10106969C1 (sr)
EA (1) EA005618B1 (sr)
EE (1) EE05131B1 (sr)
ES (1) ES2246389T3 (sr)
HR (1) HRP20030654A2 (sr)
HU (1) HUP0303030A3 (sr)
IL (2) IL157148A0 (sr)
MX (1) MXPA03007194A (sr)
NO (1) NO328106B1 (sr)
NZ (1) NZ528039A (sr)
PL (1) PL202135B1 (sr)
RS (1) RS50496B (sr)
SK (1) SK10192003A3 (sr)
UA (1) UA74874C2 (sr)
WO (1) WO2002064597A2 (sr)
ZA (1) ZA200305364B (sr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI396690B (zh) * 2006-04-27 2013-05-21 Yakult Honsha Kk 喜樹鹼衍生物的製造方法
CN102046634B (zh) * 2008-05-29 2013-04-24 日本迈科洛生物制药有限公司 喜树碱衍生物的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5527913A (en) * 1993-02-25 1996-06-18 The Stehlin Foundation For Cancer Research Methods for purifying camptothecin compounds

Also Published As

Publication number Publication date
CZ300671B6 (cs) 2009-07-15
AU2002244711B2 (en) 2007-05-31
CN1228340C (zh) 2005-11-23
EP1362051A2 (de) 2003-11-19
PL362128A1 (en) 2004-10-18
PL202135B1 (pl) 2009-06-30
UA74874C2 (en) 2006-02-15
SK10192003A3 (sk) 2004-01-08
HUP0303030A2 (hu) 2003-12-29
ES2246389T3 (es) 2006-02-16
DE10106969C1 (de) 2002-10-02
NO328106B1 (no) 2009-12-07
EP1362051B1 (de) 2005-08-03
EE05131B1 (et) 2009-02-16
WO2002064597A2 (de) 2002-08-22
KR100813087B1 (ko) 2008-03-17
CN1491228A (zh) 2004-04-21
CA2435372A1 (en) 2002-08-22
CZ20032211A3 (cs) 2003-12-17
JP2004521909A (ja) 2004-07-22
EA200300837A1 (ru) 2003-12-25
CA2435372C (en) 2010-04-20
BG108064A (bg) 2005-04-30
MXPA03007194A (es) 2003-12-04
HUP0303030A3 (en) 2004-11-29
NO20033614D0 (no) 2003-08-14
WO2002064597A3 (de) 2002-10-24
HK1064092A1 (en) 2005-01-21
DE50203824D1 (de) 2005-09-08
EE200300389A (et) 2003-12-15
ZA200305364B (en) 2004-04-28
EA005618B1 (ru) 2005-04-28
JP4467884B2 (ja) 2010-05-26
KR20030076674A (ko) 2003-09-26
NZ528039A (en) 2006-02-24
IL157148A (en) 2008-08-07
BR0207261A (pt) 2004-06-15
HRP20030654A2 (en) 2005-06-30
YU61403A (sh) 2006-05-25
NO20033614L (no) 2003-08-14
RS50496B (sr) 2010-03-02
ATE301124T1 (de) 2005-08-15

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