IL162243A0 - Indolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands - Google Patents

Indolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands

Info

Publication number: IL162243A0
Authority: IL; Israel
Prior art keywords: hydroxytryptamine; ligands; indolylalkylamine; derivatives; indolylalkylamine derivatives
Prior art date: 2001-12-20

Application number

IL16224302A

Other languages

English (en)

Original Assignee

Wyeth Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-12-20

Filing date

2002-12-17

Publication date

2005-11-20

2002-12-17 Application filed by Wyeth Corp filed Critical Wyeth Corp

2005-11-20 Publication of IL162243A0 publication Critical patent/IL162243A0/xx

Links

239000003446 ligand Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Psychiatry (AREA)
Psychology (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Indole Compounds (AREA)

IL16224302A 2001-12-20 2002-12-17 Indolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands IL162243A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US34290701P	2001-12-20	2001-12-20
PCT/US2002/040217 WO2003053433A1 (en)	2001-12-20	2002-12-17	Indolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands

Publications (1)

Publication Number	Publication Date
IL162243A0 true IL162243A0 (en)	2005-11-20

Family

ID=23343804

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL16224302A IL162243A0 (en)	2001-12-20	2002-12-17	Indolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands

Country Status (29)

Country	Link
US (2)	US6770642B2 (pl)
EP (1)	EP1455779B1 (pl)
JP (1)	JP4335684B2 (pl)
KR (1)	KR100985140B1 (pl)
CN (1)	CN1309385C (pl)
AR (1)	AR037906A1 (pl)
AT (1)	ATE335477T1 (pl)
AU (1)	AU2002357270B2 (pl)
BR (1)	BR0215222A (pl)
CA (1)	CA2470863C (pl)
CO (1)	CO5590924A2 (pl)
CY (1)	CY1105705T1 (pl)
DE (1)	DE60213856T2 (pl)
DK (1)	DK1455779T3 (pl)
EC (1)	ECSP045156A (pl)
ES (1)	ES2269827T3 (pl)
HU (1)	HUP0402640A3 (pl)
IL (1)	IL162243A0 (pl)
MX (1)	MXPA04005889A (pl)
NO (1)	NO330338B1 (pl)
NZ (1)	NZ533666A (pl)
PL (1)	PL210413B1 (pl)
PT (1)	PT1455779E (pl)
RU (1)	RU2309157C2 (pl)
SI (1)	SI1455779T1 (pl)
TW (1)	TWI254705B (pl)
UA (1)	UA78536C2 (pl)
WO (1)	WO2003053433A1 (pl)
ZA (1)	ZA200405731B (pl)

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* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1340743A4 (en) *	2000-11-09	2007-04-25	Mitsui Chemicals Inc	OPTICALLY ACTIVE AMINO DERIVATIVE AND METHOD OF SYNTHESIS
TW200301251A (en) *	2001-12-20	2003-07-01	Wyeth Corp	Azaindolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands
EP1654258A1 (en) *	2003-07-23	2006-05-10	Wyeth	Sulfonyldihydro- benzimidazolone compounds as 5-hydroxytryptamine-6 ligands
US20050032873A1 (en) *	2003-07-30	2005-02-10	Wyeth	3-Amino chroman and 2-amino tetralin derivatives
WO2005012311A1 (en) *	2003-07-31	2005-02-10	Wyeth	N-sulfonylheterocyclopyrrolylalkylamine compounds as 5-hydroxytryptamine-6 ligands
CA2534649A1 (en) *	2003-08-01	2005-02-10	Genelabs Technologies, Inc.	Bicyclic imidazol derivatives against flaviviridae
PL1704154T3 (pl) *	2004-01-02	2009-10-30	Suven Life Sciences Ltd	Nowe indeno[2,1a]indeny i izoindolo[2,1-a]indole
PE20060303A1 (es) *	2004-06-23	2006-05-19	Wyeth Corp	Metabolitos de indolilalquilamina como ligandos de 5-hidroxitriptamina-6
AU2005316675A1 (en) *	2004-12-14	2006-06-22	Wyeth	Use of a 5-HT6 agonist for the treatment and prevention of neurodegenerative disorders
US20060211698A1 (en) *	2005-01-14	2006-09-21	Genelabs, Inc.	Bicyclic heteroaryl derivatives for treating viruses
EP1953153A1 (en) *	2007-01-31	2008-08-06	Laboratorios del Dr. Esteve S.A.	Heterocyclyl-substituted sulfonamides for the treatment of cognitive or food ingestion related disorders
BRPI0811225A2 (pt) *	2007-05-24	2014-10-29	Memory Pharm Corp	Composto 4'-substituídos tendo afinidade pelo receptor 5-ht6.
EP2016943B1 (en) *	2007-07-19	2011-02-23	Laboratorios del Dr. Esteve S.A.	Substituted tetrahydro-quinoline-sulfonamide compounds, their preparation and use as medicaments
EP2053052A1 (en)	2007-10-23	2009-04-29	Laboratorios del Dr. Esteve S.A.	Process for the preparation of 6-substituted imidazo[2,1-b]thiazole-5-sulfonyl halide
EP2231160B1 (en) *	2007-12-04	2013-08-14	Merck Sharp & Dohme Corp.	Tryptamine sulfonamides as 5-ht6 antagonists
JP2011507835A (ja)	2007-12-21	2011-03-10	アンドレイ・アレクサンドロビッチ・イワシェンコ	α−アドレナリン受容体、ドーパミン、ヒスタミン、イミダゾリン及びセロトニン受容体のリガンド並びにその使用
US20100016297A1 (en) *	2008-06-24	2010-01-21	Memory Pharmaceuticals Corporation	Alkyl-substituted 3' compounds having 5-ht6 receptor affinity
US20100022581A1 (en) *	2008-07-02	2010-01-28	Memory Pharmaceuticals Corporation	Pyrrolidine-substituted azaindole compounds having 5-ht6 receptor affinity
US20100029629A1 (en) *	2008-07-25	2010-02-04	Memory Pharmaceuticals Corporation	Acyclic compounds having 5-ht6 receptor affinity
US20100056531A1 (en) *	2008-08-22	2010-03-04	Memory Pharmaceuticals Corporation	Alkyl-substituted 3' compounds having 5-ht6 receptor affinity
WO2015090233A1 (en)	2013-12-20	2015-06-25	Sunshine Lake Pharma Co., Ltd.	Aromatic heterocyclic compounds and their application in pharmaceuticals
CA2959505A1 (en) *	2014-08-29	2016-03-03	Chdi Foundation, Inc.	Probes for imaging huntingtin protein
KR102586736B1 (ko)	2014-08-29	2023-10-11	씨에이치디아이 파운데이션, 인코포레이티드	헌팅틴을 단백질 영상화하기 위한 프로브
IL311211B1 (en)	2021-09-03	2026-02-01	Alexander Shulgin Res Institute Inc	Asymmetric allyl tryptamines

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5545644A (en) *	1990-10-15	1996-08-13	Pfizer Inc.	Indole derivatives
PL172405B1 (en) *	1992-04-07	1997-09-30	Pfizer	Derivatives of indole
US6194410B1 (en)	1998-03-11	2001-02-27	Hoffman-La Roche Inc.	Pyrazolopyrimidine and pyrazolines and process for preparation thereof
US6133287A (en) *	1998-03-24	2000-10-17	Allelix Biopharmaceuticals Inc.	Piperidine-indole compounds having 5-HT6 affinity
GB9820113D0 (en) *	1998-09-15	1998-11-11	Merck Sharp & Dohme	Therapeutic agents
US6403808B1 (en) *	1999-12-10	2002-06-11	Virginia Commonwealth University	Selective 5-HT6 receptor ligands
EP1204662B1 (en) *	1999-08-12	2004-06-02	NPS Allelix Corp.	Azaindoles having serotonin receptor affinity
WO2001032660A1 (en) *	1999-11-05	2001-05-10	Nps Allelix Corp.	Compounds having 5-ht6 receptor antagonist activity
WO2001034146A1 (en) *	1999-11-08	2001-05-17	Smithkline Beecham Corporation	Novel anti-infectives

2002
- 2002-12-17 KR KR1020047009606A patent/KR100985140B1/ko not_active Expired - Fee Related
- 2002-12-17 DK DK02805601T patent/DK1455779T3/da active
- 2002-12-17 JP JP2003554190A patent/JP4335684B2/ja not_active Expired - Fee Related
- 2002-12-17 CN CNB028281721A patent/CN1309385C/zh not_active Expired - Fee Related
- 2002-12-17 MX MXPA04005889A patent/MXPA04005889A/es active IP Right Grant
- 2002-12-17 AU AU2002357270A patent/AU2002357270B2/en not_active Ceased
- 2002-12-17 AT AT02805601T patent/ATE335477T1/de active
- 2002-12-17 NZ NZ533666A patent/NZ533666A/xx not_active IP Right Cessation
- 2002-12-17 WO PCT/US2002/040217 patent/WO2003053433A1/en not_active Ceased
- 2002-12-17 ES ES02805601T patent/ES2269827T3/es not_active Expired - Lifetime
- 2002-12-17 BR BR0215222-3A patent/BR0215222A/pt not_active Application Discontinuation
- 2002-12-17 PT PT02805601T patent/PT1455779E/pt unknown
- 2002-12-17 RU RU2004122129/04A patent/RU2309157C2/ru not_active IP Right Cessation
- 2002-12-17 UA UA20040705919A patent/UA78536C2/uk unknown
- 2002-12-17 EP EP02805601A patent/EP1455779B1/en not_active Expired - Lifetime
- 2002-12-17 IL IL16224302A patent/IL162243A0/xx unknown
- 2002-12-17 CA CA2470863A patent/CA2470863C/en not_active Expired - Fee Related
- 2002-12-17 DE DE60213856T patent/DE60213856T2/de not_active Expired - Lifetime
- 2002-12-17 PL PL370711A patent/PL210413B1/pl not_active IP Right Cessation
- 2002-12-17 HU HU0402640A patent/HUP0402640A3/hu unknown
- 2002-12-17 SI SI200230401T patent/SI1455779T1/sl unknown
- 2002-12-18 AR ARP020104951A patent/AR037906A1/es unknown
- 2002-12-18 TW TW091136490A patent/TWI254705B/zh active
- 2002-12-19 US US10/323,369 patent/US6770642B2/en not_active Expired - Fee Related
2004
- 2004-04-20 US US10/828,014 patent/US7022701B2/en not_active Expired - Fee Related
- 2004-06-15 CO CO04055771A patent/CO5590924A2/es not_active Application Discontinuation
- 2004-06-16 EC EC2004005156A patent/ECSP045156A/es unknown
- 2004-07-19 ZA ZA200405731A patent/ZA200405731B/en unknown
- 2004-07-19 NO NO20043100A patent/NO330338B1/no not_active IP Right Cessation
2006
- 2006-10-13 CY CY20061101474T patent/CY1105705T1/el unknown

Also Published As

Publication number	Publication date
JP4335684B2 (ja)	2009-09-30
WO2003053433A1 (en)	2003-07-03
NO20043100L (no)	2004-08-26
CN1620290A (zh)	2005-05-25
BR0215222A (pt)	2005-05-24
HUP0402640A2 (hu)	2005-04-28
UA78536C2 (en)	2007-04-10
ES2269827T3 (es)	2007-04-01
HK1065949A1 (en)	2005-03-11
CY1105705T1 (el)	2010-12-22
US6770642B2 (en)	2004-08-03
US20040209867A1 (en)	2004-10-21
RU2309157C2 (ru)	2007-10-27
JP2005517661A (ja)	2005-06-16
RU2004122129A (ru)	2005-05-10
CA2470863A1 (en)	2003-07-03
HUP0402640A3 (en)	2012-09-28
AU2002357270A1 (en)	2003-07-09
EP1455779B1 (en)	2006-08-09
CA2470863C (en)	2012-05-15
PL370711A1 (pl)	2005-05-30
PT1455779E (pt)	2006-11-30
DE60213856D1 (de)	2006-09-21
AR037906A1 (es)	2004-12-22
ZA200405731B (en)	2007-02-28
CN1309385C (zh)	2007-04-11
AU2002357270B2 (en)	2007-06-14
TW200301252A (en)	2003-07-01
ATE335477T1 (de)	2006-09-15
TWI254705B (en)	2006-05-11
ECSP045156A (es)	2004-07-23
US7022701B2 (en)	2006-04-04
KR20040075892A (ko)	2004-08-30
DK1455779T3 (da)	2006-10-30
EP1455779A1 (en)	2004-09-15
US20030171353A1 (en)	2003-09-11
DE60213856T2 (de)	2007-09-13
CO5590924A2 (es)	2005-12-30
KR100985140B1 (ko)	2010-10-05
NZ533666A (en)	2006-03-31
NO330338B1 (no)	2011-03-28
PL210413B1 (pl)	2012-01-31
SI1455779T1 (sl)	2006-12-31
MXPA04005889A (es)	2004-11-01

Publication	Publication Date	Title
IL157059A0 (en)	2004-02-08	1-aryl-or 1-alkylsulfonylbenzazole derivatives as 5-hydroxytryptamine-6 ligands
IL158445A0 (en)	2004-05-12	Heterocyclyloxy-, -thioxy-and-aminobenzazole derivatives as 5-hydroxytryptamine-6 ligands
PL370890A1 (pl)	2005-05-30	Pochodne azaindoliloalkiloaminy jako ligandy receptora 5-hydroksytryptaminy-6
IL166139A0 (en)	2006-01-15	1-heterocycylalkyl-3-sulfonylazaindole or- azaindazole derivatives as 5-hydroxytryptamine-6 ligands
IL155443A0 (en)	2003-11-23	1- aryl- or 1-alkylsulfonyl-heterocyclylbenzazoles as 5-hydroxytryptamine-6 ligands
ZA200500435B (en)	2006-08-30	1-heterocyclyalkyl-3-sulfonylindole or -indazole derivatves as 5-hydroxytryptamine-6 ligands
SI1455779T1 (sl)	2006-12-31	Derivati indolilalkilamina kot ligandi 5-hidroksitriptamina-6
IL160701A0 (en)	2004-08-31	3-substituted-4-pyrimidone derivatives
ZA200506416B (en)	2007-02-28	Heterocyclyl-3-sulfonylindazoles as 5-hydroxytryptamine-6 ligands
IL156518A0 (en)	2004-01-04	Heteocyclylalkylindole or-azaindole compounds as 5-hydroxytryptamine-6 ligands
IL158448A0 (en)	2004-05-12	Heterocyclylalkoxy- alkylthio-and-alkylaminobenzazole derivatives as 5-hydroxytryptamine-6 ligands
HUP0401949A3 (en)	2009-07-28	4-imidazolin-2-one derivatives
HUP0303186A3 (en)	2007-06-28	4-aminobenzopyran derivatives
HUP0500026A3 (en)	2008-02-28	N-heteroarylnicotinamide derivatives
IL159064A0 (en)	2004-05-12	New phenylalkyloxy- phenyl derivatives
AU2003209114A1 (en)	2003-09-04	Pyrrolylalkylidene-hydrazinecarboximidamide derivatives as 5-hydroxytryptamine-6 ligands
EP1364954A4 (en)	2009-10-28	Dicarba closo DODECARBORANDERIVATE
HK1060128A (en)	2004-07-30	Heterocyclyloxy-, -thioxy-and-aminobenzazole derivatives as 5-hydroxytryptamine-6 ligands
HK1066002A (en)	2005-04-15	Azaindolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands
HK1060880A (en)	2004-08-27	Heterocyclylalkoxy-, -alkylthio- and - alkylaminobenzazole derivatives as 5-hydroxytryptamine-6 ligands
HK1056561A (en)	2004-02-20	1-aryl-or 1-alkylsulfonylbenzazole derivatives as 5-hydroxytryptamine-6 ligands
HK1055969A (en)	2004-01-30	1-aryl- or 1-alkylsulfonyl-heterocyclylbenzazoles as 5-hydroxytryptamine-6 ligands
HK1076464A (en)	2006-01-20	1-heterocyclylalkyl-3-sulfonylindole or -indazole derivatives as 5-hydroxytryptamine-6 ligands
HK1074619A (en)	2005-11-18	1-heterocyclylalkyl-3-sulfonylazaindole or -azaindazole derivatives as 5-hydroxytryptamine-6 ligands
AU2002334722A1 (en)	2003-04-14	Chroman derivatives as 5-hydroxytryptamine-6 ligands