IL163552A - Conjugates of biologically active compounds, uses thereof and pharmaceutical compositions comprising the same - Google Patents
Conjugates of biologically active compounds, uses thereof and pharmaceutical compositions comprising the sameInfo
- Publication number
- IL163552A IL163552A IL163552A IL16355204A IL163552A IL 163552 A IL163552 A IL 163552A IL 163552 A IL163552 A IL 163552A IL 16355204 A IL16355204 A IL 16355204A IL 163552 A IL163552 A IL 163552A
- Authority
- IL
- Israel
- Prior art keywords
- conjugates
- same
- pharmaceutical compositions
- biologically active
- active compounds
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/545—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/549—Sugars, nucleosides, nucleotides or nucleic acids
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35743402P | 2002-02-15 | 2002-02-15 | |
| PCT/US2003/004609 WO2003070174A2 (en) | 2002-02-15 | 2003-02-14 | Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof |
| US10/367,105 US7579324B2 (en) | 2002-02-15 | 2003-02-14 | Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL163552A true IL163552A (en) | 2010-11-30 |
Family
ID=27757618
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL163552A IL163552A (en) | 2002-02-15 | 2004-08-15 | Conjugates of biologically active compounds, uses thereof and pharmaceutical compositions comprising the same |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7579324B2 (de) |
| EP (1) | EP1483277A4 (de) |
| AU (1) | AU2003219770B2 (de) |
| CA (1) | CA2476423A1 (de) |
| HR (1) | HRP20040850A2 (de) |
| IL (1) | IL163552A (de) |
| NZ (1) | NZ535354A (de) |
| WO (1) | WO2003070174A2 (de) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3945985B2 (ja) * | 2000-12-28 | 2007-07-18 | 株式会社リコー | デジタルカメラ装置 |
| HRP20010018A2 (en) | 2001-01-09 | 2002-12-31 | Pliva D D | Novel anti-inflammatory compounds |
| IL160307A0 (en) | 2001-08-31 | 2004-07-25 | Univ Rockefeller | Phosphodiesterase activity and regulation of phosphodiesterase 1-b-mediated signaling in brain |
| EP1483579A4 (de) * | 2002-02-15 | 2006-07-12 | Merckle Gmbh | Konjugate biologisch aktiver verbindungen, verfahren zu ihrer herstellung und verwendung, formulierung und pharmazeutische anwendungen davon |
| US7271154B2 (en) * | 2002-02-15 | 2007-09-18 | Merckle Gmbh | Antibiotic conjugates |
| EP1521763A2 (de) | 2002-07-08 | 2005-04-13 | Pliva - Istrazivacki Institut d.o.o. | Nicht-steroidische entzündungshemmende wirkstoffe, zusammensetzungen und verfahren zu deren verwendung |
| RS20050008A (sr) * | 2002-07-08 | 2007-06-04 | Pliva-Istraživački Institut D.O.O., | Nova jedinjenja,kompozicije i metode za lečenje inflamatornih oboljenja i stanja |
| AU2003264917A1 (en) | 2002-07-08 | 2004-01-23 | Pliva - Istrazivacki Institut D.O.O. | Hybrid molecules of macrolides with steroid/non-steroid anti-inflammatory, antineoplastic and antiviral active molecules |
| TW200420573A (en) | 2002-09-26 | 2004-10-16 | Rib X Pharmaceuticals Inc | Bifunctional heterocyclic compounds and methods of making and using same |
| HRP20030324A2 (en) | 2003-04-24 | 2005-02-28 | Pliva-Istra�iva�ki institut d.o.o. | Compounds of antiinflammatory effect |
| WO2005042554A1 (en) * | 2003-10-30 | 2005-05-12 | Rib-X Pharmaceuticals, Inc. | Bifunctional macrolide heterocyclic compounds and methods of making and using the same |
| US20070270357A1 (en) * | 2003-11-18 | 2007-11-22 | Farmer Jay J | Bifunctional Macrolide Heterocyclic Compounds and Methods of Making and Using the Same |
| EP1723159B1 (de) | 2004-02-27 | 2019-06-12 | Melinta Therapeutics, Inc. | Makrozyklische verbindungen, deren herstellung und verwendung |
| US7468428B2 (en) * | 2004-03-17 | 2008-12-23 | App Pharmaceuticals, Llc | Lyophilized azithromycin formulation |
| US20060116336A1 (en) * | 2004-03-17 | 2006-06-01 | American Pharmaceutical Partners, Inc. | Lyophilized azithromycin formulation |
| KR20070046917A (ko) * | 2004-08-12 | 2007-05-03 | 글락소스미쓰클라인 이스트라지바치키 센타 자그레브 디.오.오. | 위장관의 염증성 질환의 치료를 위한 세포-특이적컨쥬게이트의 용도 |
| US20060183696A1 (en) * | 2004-08-12 | 2006-08-17 | Pliva-Istrazivacki Institut D.O.O. | Use of immune cell specific conjugates for treatment of inflammatory diseases of gastrointestinal tract |
| US7767797B1 (en) | 2004-09-30 | 2010-08-03 | Synovo Gmbh | Macrocyclic compounds and methods of use thereof |
| GB0421908D0 (en) | 2004-10-01 | 2004-11-03 | Angeletti P Ist Richerche Bio | New uses |
| ES2337915T3 (es) * | 2004-10-27 | 2010-04-30 | Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. | Conjugados con adtividad antiinflamatoria. |
| EP1846387A2 (de) * | 2005-01-14 | 2007-10-24 | GlaxoSmithKline istrazivacki centar Zagreb d.o.o. | Bis-(cumarin)-verbindungen mit entzündungshemmender wirkung |
| AU2006255028B2 (en) | 2005-06-06 | 2012-04-19 | Intra-Cellular Therapies, Inc. | Organic compounds |
| RU2008106915A (ru) * | 2005-07-26 | 2009-09-10 | Меркле Гмбх (De) | Макролидные конъюгаты пирролиновых и индолизиновых соединений |
| AU2006272496B2 (en) | 2005-07-27 | 2013-03-07 | University Of Southern California | Coumarin-based amino acids for use in enzyme activity and substrate specificity assays |
| US20080194592A1 (en) * | 2005-08-23 | 2008-08-14 | Intra-Cellular Therapies, Inc. | Organic Compounds |
| RU2455308C2 (ru) | 2006-05-01 | 2012-07-10 | Тайсо Фармасьютикал Ко., Лтд. | Макролидные производные |
| WO2008063505A1 (en) * | 2006-11-13 | 2008-05-29 | Intra-Cellular Therapies, Inc. | Organic compounds |
| WO2008070095A1 (en) | 2006-12-05 | 2008-06-12 | Intra-Cellular Therapies, Inc. | Novel uses |
| WO2010086350A1 (en) * | 2009-01-30 | 2010-08-05 | Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. | 9-deoxo- 9a-methyl- 9a- aza- 9a-h0m0erythr0mycin a derivatives for the treatment of neutrophil dominated inflammatory diseases |
| WO2010098839A1 (en) | 2009-02-25 | 2010-09-02 | Intra-Cellular Therapies, Inc. | Pde 1 inhibitors for ophthalmic disorders |
| JP2012526810A (ja) | 2009-05-13 | 2012-11-01 | イントラ−セルラー・セラピーズ・インコーポレイテッド | 有機化合物 |
| JP6166534B2 (ja) | 2009-08-05 | 2017-07-19 | イントラ−セルラー・セラピーズ・インコーポレイテッドＩｎｔｒａ−Ｃｅｌｌｕｌａｒ Ｔｈｅｒａｐｉｅｓ， Ｉｎｃ． | 新規調節タンパク質および阻害剤 |
| EP2625185A4 (de) * | 2010-10-10 | 2014-03-26 | Synovo Gmbh | Entzündungshemmende makrolide |
| AU2013239679A1 (en) | 2012-03-27 | 2014-10-30 | Michael W. BURNET | Anti-inflammatory macrolides |
| AU2013263349B2 (en) | 2012-05-17 | 2016-09-08 | Extend Biosciences, Inc | Carriers for improved drug delivery |
| US9801882B2 (en) | 2013-02-17 | 2017-10-31 | Intra-Cellular Therapies, Inc. | Phosphodiesterase-1 inhibitors and their use in treatment of cardiovascular diseases |
| KR102240326B1 (ko) | 2013-03-15 | 2021-04-13 | 인트라-셀룰라 써래피스, 인코퍼레이티드. | 유기 화합물 |
| EP2968338B1 (de) | 2013-03-15 | 2019-01-09 | Intra-Cellular Therapies, Inc. | Pde1-inhibitoren zur verwendung bei der behandlung und/oder prävention von zns-verletzungen und pns-krankheiten, störungen oder verletzungen |
| EP3157926B1 (de) | 2014-06-20 | 2019-05-15 | Intra-Cellular Therapies, Inc. | Organische verbindungen |
| US10131671B2 (en) | 2014-08-07 | 2018-11-20 | Intra-Cellular Therapies, Inc. | Organic compounds |
| US10285992B2 (en) | 2014-08-07 | 2019-05-14 | Intra-Cellular Therapies, Inc. | Combinations of PDE1 inhibitors and NEP inhibitors and associated methods |
| CA2961212C (en) | 2014-09-17 | 2024-02-06 | Intra-Cellular Therapies, Inc. | Compounds and methods |
| US9616109B2 (en) | 2014-10-22 | 2017-04-11 | Extend Biosciences, Inc. | Insulin vitamin D conjugates |
| US9789197B2 (en) | 2014-10-22 | 2017-10-17 | Extend Biosciences, Inc. | RNAi vitamin D conjugates |
| WO2016065042A1 (en) | 2014-10-22 | 2016-04-28 | Extend Biosciences, Inc. | Therapeutic vitamin d conjugates |
| GB201520419D0 (en) | 2015-11-19 | 2016-01-06 | Epi Endo Pharmaceuticals Ehf | Compounds |
| US10682354B2 (en) | 2016-03-28 | 2020-06-16 | Intra-Cellular Therapies, Inc. | Compositions and methods |
| JP7134168B6 (ja) | 2016-09-12 | 2024-02-02 | イントラ－セルラー・セラピーズ・インコーポレイテッド | 新規使用 |
| JP7401442B2 (ja) | 2018-01-31 | 2023-12-19 | イントラ－セルラー・セラピーズ・インコーポレイテッド | 新規使用 |
| EP3955937A4 (de) * | 2019-04-18 | 2023-01-18 | Azura Ophthalmics Ltd. | Verbindungen und zusammensetzungen zur behandlung von augenkrankheiten |
| EP4413980A3 (de) | 2019-09-03 | 2024-10-30 | Intra-Cellular Therapies, Inc. | Neue verbindungen |
| US12364695B2 (en) | 2020-06-02 | 2025-07-22 | Intra-Cellular Therapies, Inc. | Methods of treating inflammatory disease |
| WO2023248010A2 (en) | 2022-06-23 | 2023-12-28 | Synovo Gmbh | Targeted modulators of jak3 for treatment of inflammatory and autoimmune diseases |
| KR20250075704A (ko) | 2022-09-30 | 2025-05-28 | 익스텐드 바이오사이언시즈, 인크. | 장기-지속형 부갑상선 호르몬 |
| GB202404587D0 (en) | 2024-03-28 | 2024-05-15 | Epiendo Pharmaceuticals Ehf | Chemical forms |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3417077A (en) | 1966-05-16 | 1968-12-17 | Lilly Co Eli | Erythromycin derivative and process for the preparation thereof |
| US4375414A (en) * | 1971-05-20 | 1983-03-01 | Meir Strahilevitz | Immunological methods for removing species from the blood circulatory system and devices therefor |
| US3884903A (en) | 1973-06-21 | 1975-05-20 | Abbott Lab | 4{41 -Deoxy-4{41 -oxoerythromycin B derivatives |
| EP0009944B1 (de) | 1978-10-02 | 1983-05-18 | Merck & Co. Inc. | Lysosomotropische therapeutische fluorierte Aminverbindungen und sie enthaltende Zusammensetzungen |
| YU43116B (en) * | 1979-04-02 | 1989-04-30 | Pliva Pharm & Chem Works | Process for preparing 11-aza-4-o-cladinosyl-6-o-desosaminyl-15-ethyl-7,13,14-trihydroxy-3,5,7,9,12,14-hexamethyl-oxacyclopentadecane-2-one(11-aza-10-deox |
| SI8110592A8 (en) | 1981-03-06 | 1996-06-30 | Pliva Pharm & Chem Works | Process for preparing of n-methyl-11-aza-10-deoxo-10-dihydroerythromycine a and derivatives thereof |
| US4382086A (en) * | 1982-03-01 | 1983-05-03 | Pfizer Inc. | 9-Dihydro-11,12-ketal derivatives of erythromycin A and epi-erythromycin A |
| US4474768A (en) * | 1982-07-19 | 1984-10-02 | Pfizer Inc. | N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor |
| US4518590A (en) | 1984-04-13 | 1985-05-21 | Pfizer Inc. | 9α-Aza-9α-homoerythromycin compounds, pharmaceutical compositions and therapeutic method |
| US4585759A (en) | 1985-01-22 | 1986-04-29 | Pfizer Inc. | Antibacterial derivatives of a neutral macrolide |
| JPH0720857B2 (ja) | 1988-08-11 | 1995-03-08 | テルモ株式会社 | リポソームおよびその製法 |
| US5466681A (en) * | 1990-02-23 | 1995-11-14 | Microcarb, Inc. | Receptor conjugates for targeting penicillin antibiotics to bacteria |
| US5405975A (en) | 1993-03-29 | 1995-04-11 | Molecular Probes, Inc. | Fluorescent ion-selective diaryldiaza crown ether conjugates |
| SI9011409A (en) | 1990-07-18 | 1995-10-31 | Pliva Pharm & Chem Works | O-methyl azitromycin derivates, methods and intermediates for their preparation and methods for preparation of pharmaceuticals products which comprise them |
| JPH07103148B2 (ja) | 1991-12-16 | 1995-11-08 | 株式会社ディ・ディ・エス研究所 | アントラサイクリン−マクロライド複合体 |
| US20030068362A1 (en) * | 1993-02-22 | 2003-04-10 | American Bioscience, Inc. | Methods and formulations for the delivery of pharmacologically active agents |
| US5486536A (en) * | 1994-08-15 | 1996-01-23 | The Regents Of The University Of Michigan | Sulfatides as anti-inflammatory compounds |
| US5750493A (en) * | 1995-08-30 | 1998-05-12 | Raymond F. Schinazi | Method to improve the biological and antiviral activity of protease inhibitors |
| FR2738571B1 (fr) * | 1995-09-11 | 1997-10-17 | Roussel Uclaf | Nouveaux derives de la 5-0-desosaminyl 6-0-methyl- erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs |
| CA2252886C (en) * | 1996-04-26 | 2008-02-12 | Massachusetts Institute Of Technology | Three-hybrid screening assay |
| AU5775698A (en) | 1996-12-30 | 1998-07-31 | Governors Of The University Of Alberta, The | Mammalian equilibrative nucleoside transporters |
| US5827533A (en) * | 1997-02-06 | 1998-10-27 | Duke University | Liposomes containing active agents aggregated with lipid surfactants |
| EP0895999A1 (de) | 1997-08-06 | 1999-02-10 | Pfizer Products Inc. | C-4"-substituierte Macrolidantibiotica |
| DK1036083T5 (da) | 1997-10-16 | 2005-04-04 | Pliva Istrazivacki Inst D O O | Nye 9A-azalider |
| HRP980189B1 (en) | 1998-04-06 | 2004-04-30 | Pliva Pharm & Chem Works | Novel 15-membered lactams ketolides |
| US6288234B1 (en) | 1998-06-08 | 2001-09-11 | Advanced Medicine, Inc. | Multibinding inhibitors of microsomal triglyceride transferase protein |
| AU4543799A (en) | 1998-06-08 | 1999-12-30 | Theravance, Inc. | Combinatorial synthesis of multibinding libraries |
| WO1999064040A1 (en) | 1998-06-08 | 1999-12-16 | Advanced Medicine, Inc. | Novel polyene macrolide compounds and uses |
| US6043227A (en) | 1998-08-19 | 2000-03-28 | Pfizer Inc. | C11 carbamates of macrolide antibacterials |
| US6100240A (en) | 1998-10-09 | 2000-08-08 | Pfizer Inc | Macrolide derivatives |
| US6593292B1 (en) | 1999-08-24 | 2003-07-15 | Cellgate, Inc. | Compositions and methods for enhancing drug delivery across and into epithelial tissues |
| US7413536B1 (en) | 1999-09-14 | 2008-08-19 | Xenoport, Inc. | Substrates and screening methods for transport proteins |
| ID27331A (id) | 1999-09-29 | 2001-03-29 | Pfizer Prod Inc | Pembuatan antibiotik-antibiotik ketolida karbamat |
| WO2001051061A1 (en) * | 2000-01-14 | 2001-07-19 | Intrabiotics Pharmaceuticals, Inc. | Derivatives of polyene macrolides and preparation and use thereof |
| EP1122261A3 (de) | 2000-01-31 | 2001-09-26 | Pfizer Products Inc. | 13- und 14-Gliederige Antibakterielle-Makroliden |
| EP1167376B1 (de) | 2000-06-30 | 2004-07-14 | Pfizer Products Inc. | Makrolid-Antibiotika |
| HRP20010018A2 (en) * | 2001-01-09 | 2002-12-31 | Pliva D D | Novel anti-inflammatory compounds |
| CA2465846A1 (en) | 2001-11-21 | 2003-06-05 | Activbiotics, Inc. | Targeted therapeutics and uses thereof |
| EP1483579A4 (de) * | 2002-02-15 | 2006-07-12 | Merckle Gmbh | Konjugate biologisch aktiver verbindungen, verfahren zu ihrer herstellung und verwendung, formulierung und pharmazeutische anwendungen davon |
| US7271154B2 (en) | 2002-02-15 | 2007-09-18 | Merckle Gmbh | Antibiotic conjugates |
| RS20050008A (sr) * | 2002-07-08 | 2007-06-04 | Pliva-Istraživački Institut D.O.O., | Nova jedinjenja,kompozicije i metode za lečenje inflamatornih oboljenja i stanja |
-
2003
- 2003-02-14 AU AU2003219770A patent/AU2003219770B2/en not_active Ceased
- 2003-02-14 WO PCT/US2003/004609 patent/WO2003070174A2/en not_active Ceased
- 2003-02-14 NZ NZ535354A patent/NZ535354A/en unknown
- 2003-02-14 US US10/367,105 patent/US7579324B2/en not_active Expired - Fee Related
- 2003-02-14 US US10/504,787 patent/US20050171342A1/en not_active Abandoned
- 2003-02-14 HR HR20040850A patent/HRP20040850A2/hr not_active Application Discontinuation
- 2003-02-14 CA CA002476423A patent/CA2476423A1/en not_active Abandoned
- 2003-02-14 EP EP03716044A patent/EP1483277A4/de not_active Withdrawn
-
2004
- 2004-08-15 IL IL163552A patent/IL163552A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US20050171342A1 (en) | 2005-08-04 |
| US20040087517A1 (en) | 2004-05-06 |
| NZ535354A (en) | 2008-01-31 |
| EP1483277A2 (de) | 2004-12-08 |
| US7579324B2 (en) | 2009-08-25 |
| AU2003219770A1 (en) | 2003-09-09 |
| WO2003070174A3 (en) | 2003-11-13 |
| AU2003219770B2 (en) | 2008-10-09 |
| WO2003070174A2 (en) | 2003-08-28 |
| HRP20040850A2 (en) | 2005-08-31 |
| CA2476423A1 (en) | 2003-08-28 |
| EP1483277A4 (de) | 2007-10-03 |
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