IL163849A0 - Stable pharmaceutical compositions containing factor VIII - Google Patents

Stable pharmaceutical compositions containing factor VIII

Info

Publication number: IL163849A0
Authority: IL; Israel
Prior art keywords: pharmaceutical compositions; compositions containing; factor viii; stable pharmaceutical; containing factor
Prior art date: 2002-03-26

Application number

IL16384903A

Other languages

English (en)

Original Assignee

Conseils De Rech S Et D Aplica

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-03-26

Filing date

2003-03-26

Publication date

2005-12-18

2003-03-26 Application filed by Conseils De Rech S Et D Aplica filed Critical Conseils De Rech S Et D Aplica

2005-12-18 Publication of IL163849A0 publication Critical patent/IL163849A0/xx

Links

102000001690 Factor VIII Human genes 0.000 title 1
108010054218 Factor VIII Proteins 0.000 title 1
229960000301 factor viii Drugs 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A61K38/37—Factors VIII
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Hematology (AREA)
Oil, Petroleum & Natural Gas (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Diabetes (AREA)
Dermatology (AREA)
Organic Chemistry (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Peptides Or Proteins (AREA)

IL16384903A 2002-03-26 2003-03-26 Stable pharmaceutical compositions containing factor VIII IL163849A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0207092.8A GB0207092D0 (en)	2002-03-26	2002-03-26	Stable pharmaceutical composition containing factor VIII
PCT/GB2003/001297 WO2003080108A1 (en)	2002-03-26	2003-03-26	Stable pharmaceutical composition containing factor viii

Publications (1)

Publication Number	Publication Date
IL163849A0 true IL163849A0 (en)	2005-12-18

Family

ID=9933726

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IL16384903A IL163849A0 (en)	2002-03-26	2003-03-26	Stable pharmaceutical compositions containing factor VIII
IL163849A IL163849A (en)	2002-03-26	2004-08-31	Stable pharmaceutical compositions containing factor viii and a liquid pharmaceutical composition obtained therefrom

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
IL163849A IL163849A (en)	2002-03-26	2004-08-31	Stable pharmaceutical compositions containing factor viii and a liquid pharmaceutical composition obtained therefrom

Country Status (26)

Country	Link
US (1)	US7790680B2 (de)
EP (2)	EP2292216A3 (de)
JP (4)	JP2005530714A (de)
KR (1)	KR20040093482A (de)
CN (2)	CN1642570B (de)
AR (1)	AR039123A1 (de)
AT (1)	ATE477814T1 (de)
AU (1)	AU2003217030B2 (de)
BR (1)	BR0308442A (de)
CA (1)	CA2480226C (de)
DE (1)	DE60333825D1 (de)
DK (1)	DK1490095T3 (de)
ES (1)	ES2350337T3 (de)
GB (1)	GB0207092D0 (de)
HR (1)	HRP20040882B1 (de)
IL (2)	IL163849A0 (de)
IS (1)	IS7458A (de)
MX (1)	MXPA04009275A (de)
MY (1)	MY149831A (de)
NO (1)	NO328450B1 (de)
NZ (1)	NZ535032A (de)
PL (1)	PL208009B1 (de)
PT (1)	PT1490095E (de)
RU (1)	RU2314825C2 (de)
TW (1)	TWI285106B (de)
WO (1)	WO2003080108A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7560107B2 (en)	1996-06-26	2009-07-14	Emory University	Modified factor VIII
JP2006504772A (ja) *	2002-10-29	2006-02-09	アルザ・コーポレーション	安定化された固体ポリペプチド粒子
WO2005017149A1 (en)	2003-06-03	2005-02-24	Cell Genesys, Inc.	Compositions and methods for enhanced expression of recombinant polypeptides from a single vector using a peptide cleavage site
US7485291B2 (en)	2003-06-03	2009-02-03	Cell Genesys, Inc.	Compositions and methods for generating multiple polypeptides from a single vector using a virus derived peptide cleavage site, and uses thereof
AU2004288854B2 (en) *	2003-11-10	2009-10-01	Arriva-Pharmaceuticals, Inc.	Dry recombinant human alpha 1-antitrypsin formulation
PL1750733T3 (pl) *	2004-05-03	2014-05-30	Univ Emory	Sposób podawania świńskiego czynnika krzepnięcia VIII pozbawionego domeny B
WO2009130181A2 (en) *	2008-04-21	2009-10-29	Novo Nordisk Health Care Ag	Dry transglutaminase composition
EP2113564A1 (de)	2008-05-01	2009-11-04	Arecor Limited	Proteinformulierung
WO2010020690A1 (en)	2008-08-21	2010-02-25	Octapharma Ag	Recombinantly produced human factor viii and ix
KR101691070B1 (ko) *	2008-09-03	2016-12-29	옥타파마 아게	재조합에 의해 제조된 인자 ⅷ을 위한 신규한 보호 조성물
EP2385825B1 (de)	2008-11-07	2018-10-10	University of Connecticut	Faktor-viii-formulierungen
GB0915480D0 (en) *	2009-09-04	2009-10-07	Arecor Ltd	Stable formulation of factor viii
BR112013011041B1 (pt)	2010-11-05	2021-05-25	Baxalta GmbH	variante de fator viii, método para produzir uma variante de fviii, uso da variante de fator viii, e, composição farmacêutica
ES2926798T3 (es)	2013-03-15	2022-10-28	Bioverativ Therapeutics Inc	Formulaciones de polipéptido de factor VIII
AU2014237111B2 (en) *	2013-03-15	2018-06-21	Bayer Healthcare Llc	Recombinant factor VIII formulations
JP6516829B2 (ja)	2014-08-04	2019-05-22	シーエスエル、リミテッド	第ｖｉｉｉ因子製剤
US20180200325A1 (en) *	2014-11-18	2018-07-19	Shionogi & Co., Ltd.	Stabilized peptide composition
WO2021001522A1 (en)	2019-07-04	2021-01-07	CSL Behring Lengnau AG	A truncated von willebrand factor (vwf) for increasing the in vitro stability of coagulation factor viii
EP4240757A2 (de)	2020-11-09	2023-09-13	Takeda Pharmaceutical Company Limited	Reinigung von fviii aus plasma mittels siliciumoxidadsorption

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6281327A (ja) *	1985-10-04	1987-04-14	Green Cross Corp:The	人トロンビン製剤の加熱処理方法
JPS6485927A (en)	1987-09-29	1989-03-30	Green Cross Corp	Hepatitis b vaccine
US5605884A (en)	1987-10-29	1997-02-25	Rhone-Poulenc Rorer Pharmaceuticals Inc.	Factor VIII formulations in high ionic strength media
WO1989009784A1 (en) *	1988-04-08	1989-10-19	Commonwealth Serum Laboratories Commission	Production of heat-stable factor viii concentrate
GB8822857D0 (en) *	1988-09-29	1988-11-02	Patralan Ltd	Pharmaceutical formulations
SE465222C5 (sv)	1989-12-15	1998-02-10	Pharmacia & Upjohn Ab	Ett rekombinant, humant faktor VIII-derivat och förfarande för dess framställning
IE64738B1 (en) *	1990-03-20	1995-09-06	Akzo Nv	Stabilized gonadotropin containing preparations
DE4111393A1 (de)	1991-04-09	1992-10-15	Behringwerke Ag	Stabilisierte faktor viii-praeparationen
ATE198277T1 (de)	1992-10-02	2001-01-15	Genetics Inst	Zusammensetzung, welche den koagulationsfaktor viii beinhaltet; verfahren zu deren herstellung und die benutzung eines oberflächenaktiven stoffes als stabilisator
SE9301581D0 (sv)	1993-05-07	1993-05-07	Kabi Pharmacia Ab	Protein formulation
SE504074C2 (sv)	1993-07-05	1996-11-04	Pharmacia Ab	Proteinberedning för subkutan, intramuskulär eller intradermal administrering
ZA955642B (en) *	1994-07-07	1997-05-06	Ortho Pharma Corp	Lyophilized imaging agent formulation
JPH0899999A (ja)	1994-09-30	1996-04-16	Chemo Sero Therapeut Res Inst	α１プロテアーゼインヒビターの製造方法
US6458563B1 (en) *	1996-06-26	2002-10-01	Emory University	Modified factor VIII
US5763401A (en)	1996-07-12	1998-06-09	Bayer Corporation	Stabilized albumin-free recombinant factor VIII preparation having a low sugar content
EP1820516B1 (de) *	1999-02-22	2013-07-24	University of Connecticut	Neue albuminfreie Faktor VIII Formulierungen
EP1194161B1 (de) *	1999-07-13	2005-11-23	Biovitrum Ab	Zusammensetzungen mit stabilem faktor viii
US6586574B1 (en) *	1999-08-17	2003-07-01	Nn A/S	Stabilization of freeze-dried cake
ATE264340T1 (de) *	1999-08-17	2004-04-15	Novo Nordisk Healthcare Ag	Stabilisierung von gefriergetrocknetem kuchen
US7576182B1 (en) *	1999-08-31	2009-08-18	Genentech, Inc.	Compositions and methods for the treatment of immune related diseases

2002
- 2002-03-26 GB GBGB0207092.8A patent/GB0207092D0/en not_active Ceased
2003
- 2003-03-14 TW TW092105665A patent/TWI285106B/zh not_active IP Right Cessation
- 2003-03-19 MY MYPI20030960A patent/MY149831A/en unknown
- 2003-03-25 AR ARP030101024A patent/AR039123A1/es not_active Application Discontinuation
- 2003-03-26 RU RU2004131556/15A patent/RU2314825C2/ru active
- 2003-03-26 WO PCT/GB2003/001297 patent/WO2003080108A1/en not_active Ceased
- 2003-03-26 PL PL372414A patent/PL208009B1/pl unknown
- 2003-03-26 PT PT03712418T patent/PT1490095E/pt unknown
- 2003-03-26 EP EP10172869A patent/EP2292216A3/de not_active Withdrawn
- 2003-03-26 CN CN038069911A patent/CN1642570B/zh not_active Expired - Lifetime
- 2003-03-26 MX MXPA04009275A patent/MXPA04009275A/es active IP Right Grant
- 2003-03-26 CA CA2480226A patent/CA2480226C/en not_active Expired - Lifetime
- 2003-03-26 DE DE60333825T patent/DE60333825D1/de not_active Expired - Lifetime
- 2003-03-26 AT AT03712418T patent/ATE477814T1/de active
- 2003-03-26 US US10/507,956 patent/US7790680B2/en not_active Expired - Lifetime
- 2003-03-26 DK DK03712418.7T patent/DK1490095T3/da active
- 2003-03-26 NZ NZ535032A patent/NZ535032A/xx not_active IP Right Cessation
- 2003-03-26 ES ES03712418T patent/ES2350337T3/es not_active Expired - Lifetime
- 2003-03-26 IL IL16384903A patent/IL163849A0/xx unknown
- 2003-03-26 CN CN201210563117.1A patent/CN103006540B/zh not_active Expired - Lifetime
- 2003-03-26 EP EP03712418A patent/EP1490095B1/de not_active Expired - Lifetime
- 2003-03-26 HR HRP20040882AA patent/HRP20040882B1/hr not_active IP Right Cessation
- 2003-03-26 JP JP2003577934A patent/JP2005530714A/ja active Pending
- 2003-03-26 KR KR10-2004-7015295A patent/KR20040093482A/ko not_active Ceased
- 2003-03-26 BR BR0308442-6A patent/BR0308442A/pt not_active Application Discontinuation
- 2003-03-26 AU AU2003217030A patent/AU2003217030B2/en not_active Expired
2004
- 2004-08-31 IL IL163849A patent/IL163849A/en not_active IP Right Cessation
- 2004-09-17 IS IS7458A patent/IS7458A/is unknown
- 2004-10-11 NO NO20044305A patent/NO328450B1/no not_active IP Right Cessation
2011
- 2011-01-07 JP JP2011002185A patent/JP2011079862A/ja active Pending
2013
- 2013-04-16 JP JP2013085801A patent/JP5770775B2/ja not_active Expired - Lifetime
2015
- 2015-03-18 JP JP2015055071A patent/JP2015143245A/ja active Pending

Also Published As

Publication number	Publication date
IS7458A (is)	2004-09-17
EP1490095A1 (de)	2004-12-29
WO2003080108A1 (en)	2003-10-02
TWI285106B (en)	2007-08-11
US20050256038A1 (en)	2005-11-17
IL163849A (en)	2010-12-30
EP2292216A2 (de)	2011-03-09
HK1080713A1 (en)	2006-05-04
BR0308442A (pt)	2005-01-18
MXPA04009275A (es)	2005-01-25
AU2003217030A1 (en)	2003-10-08
HK1183446A1 (en)	2013-12-27
ES2350337T3 (es)	2011-01-21
TW200304827A (en)	2003-10-16
CN1642570B (zh)	2013-01-09
JP2013147508A (ja)	2013-08-01
ATE477814T1 (de)	2010-09-15
KR20040093482A (ko)	2004-11-05
RU2314825C2 (ru)	2008-01-20
JP5770775B2 (ja)	2015-08-26
AR039123A1 (es)	2005-02-09
HRP20040882B1 (hr)	2013-02-28
AU2003217030B2 (en)	2008-12-04
US7790680B2 (en)	2010-09-07
EP1490095B1 (de)	2010-08-18
HRP20040882A2 (en)	2004-12-31
PL208009B1 (pl)	2011-03-31
CN1642570A (zh)	2005-07-20
DK1490095T3 (da)	2010-11-08
NO20044305L (no)	2004-10-11
PL372414A1 (en)	2005-07-25
CA2480226A1 (en)	2003-10-02
CN103006540A (zh)	2013-04-03
RU2004131556A (ru)	2005-08-20
MY149831A (en)	2013-10-31
CN103006540B (zh)	2015-09-16
JP2011079862A (ja)	2011-04-21
GB0207092D0 (en)	2002-05-08
NZ535032A (en)	2006-03-31
JP2015143245A (ja)	2015-08-06
PT1490095E (pt)	2010-10-21
CA2480226C (en)	2012-09-18
NO328450B1 (no)	2010-02-22
EP2292216A3 (de)	2011-05-11
JP2005530714A (ja)	2005-10-13
DE60333825D1 (de)	2010-09-30

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