IL57324A - 3-substituted-6-alkanoylamino-1,3,5-triazine-2,4-diones,process for their preparation and pharmaceutical compositions containing them - Google Patents

3-substituted-6-alkanoylamino-1,3,5-triazine-2,4-diones,process for their preparation and pharmaceutical compositions containing them

Info

Publication number: IL57324A
Authority: IL; Israel
Prior art keywords: alkyl; radical; pharmaceutical compositions; phenyl; diones
Prior art date: 1978-05-26

Application number

IL57324A

Other languages

English (en)

Other versions

IL57324A0 (en

Original Assignee

Ici Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-05-26

Filing date

1979-05-17

Publication date

1983-10-31

1979-05-17 Application filed by Ici Ltd filed Critical Ici Ltd

1979-09-30 Publication of IL57324A0 publication Critical patent/IL57324A0/xx

1983-10-31 Publication of IL57324A publication Critical patent/IL57324A/xx

Links

238000000034 method Methods 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 title abstract 2
-1 alkyl radical Chemical class 0.000 abstract 3
125000000217 alkyl group Chemical group 0.000 abstract 2
125000000753 cycloalkyl group Chemical group 0.000 abstract 2
125000002950 monocyclic group Chemical group 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
125000000166 1,3-dioxalanyl group Chemical group 0.000 abstract 1
102000004005 Prostaglandin-endoperoxide synthases Human genes 0.000 abstract 1
108090000459 Prostaglandin-endoperoxide synthases Proteins 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
230000000202 analgesic effect Effects 0.000 abstract 1
230000003110 anti-inflammatory effect Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical compound [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 abstract 1
125000003718 tetrahydrofuranyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
- C07D251/38—Sulfur atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
- C07D251/40—Nitrogen atoms
- C07D251/42—One nitrogen atom
- C07D251/46—One nitrogen atom with oxygen or sulfur atoms attached to the two other ring carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pain & Pain Management (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

IL57324A 1978-05-26 1979-05-17 3-substituted-6-alkanoylamino-1,3,5-triazine-2,4-diones,process for their preparation and pharmaceutical compositions containing them IL57324A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB2293878		1978-05-26

Publications (2)

Publication Number	Publication Date
IL57324A0 IL57324A0 (en)	1979-09-30
IL57324A true IL57324A (en)	1983-10-31

Family

ID=10187501

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL57324A IL57324A (en)	1978-05-26	1979-05-17	3-substituted-6-alkanoylamino-1,3,5-triazine-2,4-diones,process for their preparation and pharmaceutical compositions containing them

Country Status (24)

Country	Link
US (1)	US4254122A (de)
EP (1)	EP0005911B1 (de)
JP (1)	JPS54154779A (de)
AT (1)	ATE698T1 (de)
AU (1)	AU529948B2 (de)
CA (1)	CA1108138A (de)
CS (1)	CS213377B2 (de)
DD (1)	DD143906A5 (de)
DE (1)	DE2962124D1 (de)
DK (1)	DK213179A (de)
ES (1)	ES480932A1 (de)
FI (1)	FI66180C (de)
GR (1)	GR68185B (de)
HU (1)	HU180252B (de)
IE (1)	IE49170B1 (de)
IL (1)	IL57324A (de)
MW (1)	MW1379A1 (de)
NO (1)	NO791722L (de)
NZ (1)	NZ190402A (de)
PH (1)	PH14793A (de)
PT (1)	PT69650A (de)
ZA (1)	ZA792247B (de)
ZM (1)	ZM4579A1 (de)
ZW (1)	ZW9179A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8629567D0 (en) *	1986-12-10	1987-01-21	Boots Co Plc	Therapeutic agents
US6348216B1 (en) *	1996-06-10	2002-02-19	Knoll Pharmaceutical Company	Ibuprofen and narcotic analgesic compositions
US6361794B1 (en)	1996-06-12	2002-03-26	Basf Corporation	Method of making ibuprofen and narcotic analgesic composition
WO1998049150A1 (en) *	1997-04-25	1998-11-05	Takeda Chemical Industries, Ltd.	Triazine derivatives, their production and agrochemical composition
US6335339B1 (en)	1998-01-13	2002-01-01	Scriptgen Pharmaceuticals, Inc.	Triazine antiviral compounds
JP2005532295A (ja) *	2002-04-17	2005-10-27	メディカルリサーチカウンシル	月経過多を治療するためのＦＰレセプターアンタゴニスト又はＰＧＦ２αアンタゴニスト
EP1660072A2 (de) *	2003-07-29	2006-05-31	Universitätsklinikum Münster	Mittel und verfahren zur behandlung einer erkrankung, die mit einem überschüssigen transport von hyaluronan über eine lipid-bischicht verbunden ist
US7199156B2 (en) *	2003-10-10	2007-04-03	Milos Chvapil	Composition and method to treat solid tumors
TW200517114A (en) *	2003-10-15	2005-06-01	Combinatorx Inc	Methods and reagents for the treatment of immunoinflammatory disorders
CA2652773A1 (en) *	2006-05-22	2007-12-06	Combinatorx, Incorporated	Methods and compositions for the treatment of diseases or conditions associated with increased c-reactive protein, interleukin-6, or interferon-gamma levels
CA2737131A1 (en) *	2007-09-19	2009-03-26	Zalicus Inc.	Therapeutic regimens for the treatment of immunoinflammatory disorders
KR20100121601A (ko) *	2007-12-17	2010-11-18	콤비네이토릭스, 인코포레이티드	면역염증성 질환의 치료를 위한 치료요법
MX2011008362A (es)	2009-02-13	2011-08-24	Shionogi & Co	Derivado novedoso de triazina y composicion farmaceutica que comprende el mismo.
DK2604595T3 (en)	2010-08-10	2016-05-23	Shionogi & Co	TRIAZINE DERIVATIVES AND PHARMACEUTICAL RELATIONSHIP CONTAINING THIS AND PROVIDING ANALGETIC ACTIVITY
EP2604260B1 (de)	2010-08-10	2017-05-10	Shionogi&Co., Ltd.	Neue heterozyklische derivate und pharmazeutische zusammensetzung damit
WO2013118855A1 (ja)	2012-02-09	2013-08-15	塩野義製薬株式会社	複素環および炭素環誘導体
TWI637949B (zh)	2013-06-14	2018-10-11	塩野義製藥股份有限公司	胺基三衍生物及含有其等之醫藥組合物
WO2022162689A1 (en) *	2021-01-26	2022-08-04	Council Of Scientific And Industrial Research	Triazine-based self-assembling system
TW202302541A (zh) *	2021-03-17	2023-01-16	美商翰森生物有限責任公司	含氮雜環酮、其製備方法和醫藥用途
CN120574183B (zh) *	2025-07-31	2025-11-21	潍坊鑫洋化工有限公司	一种溴代三嗪的合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3983116A (en) *	1973-04-05	1976-09-28	E. I. Du Pont De Nemours And Company	Herbicidal triazines
GB1543037A (en) *	1975-02-05	1979-03-28	Ici Ltd	Selective herbicidal triazine-diones
US4082536A (en) *	1973-11-01	1978-04-04	Imperial Chemical Industries Limited	Heterocyclic compounds and their use as pesticides
US4035365A (en) *	1973-11-01	1977-07-12	Imperial Chemical Industries Limited	Triazinediones
GB1464248A (en)	1973-11-01	1977-02-09	Ici Ltd	Substituted triazinediones their preparation and use as herbicides
GB1504304A (en) *	1974-02-15	1978-03-15	Ici Ltd	Process of combating fungal and bacterial infections of plants with triazine dione derivatives
GB1599518A (en) *	1977-02-21	1981-10-07	Ici Ltd	1,3,5-triazine-2,6-diones and pharmaceutical compositions thereof

1979
- 1979-05-02 EP EP79300756A patent/EP0005911B1/de not_active Expired
- 1979-05-02 DE DE7979300756T patent/DE2962124D1/de not_active Expired
- 1979-05-02 AT AT79300756T patent/ATE698T1/de not_active IP Right Cessation
- 1979-05-07 US US06/036,508 patent/US4254122A/en not_active Expired - Lifetime
- 1979-05-07 CA CA327,103A patent/CA1108138A/en not_active Expired
- 1979-05-09 ZA ZA792247A patent/ZA792247B/xx unknown
- 1979-05-09 NZ NZ190402A patent/NZ190402A/xx unknown
- 1979-05-10 AU AU46949/79A patent/AU529948B2/en not_active Ceased
- 1979-05-15 ZW ZW91/79A patent/ZW9179A1/xx unknown
- 1979-05-17 IL IL57324A patent/IL57324A/xx unknown
- 1979-05-17 MW MW13/79A patent/MW1379A1/xx unknown
- 1979-05-19 GR GR59133A patent/GR68185B/el unknown
- 1979-05-21 PH PH22523A patent/PH14793A/en unknown
- 1979-05-22 HU HU79IE875A patent/HU180252B/hu unknown
- 1979-05-22 PT PT69650A patent/PT69650A/pt unknown
- 1979-05-23 DK DK213179A patent/DK213179A/da not_active Application Discontinuation
- 1979-05-23 ZM ZM45/79A patent/ZM4579A1/xx unknown
- 1979-05-25 DD DD79213155A patent/DD143906A5/de unknown
- 1979-05-25 ES ES480932A patent/ES480932A1/es not_active Expired
- 1979-05-25 NO NO791722A patent/NO791722L/no unknown
- 1979-05-25 CS CS793623A patent/CS213377B2/cs unknown
- 1979-05-25 FI FI791670A patent/FI66180C/fi not_active IP Right Cessation
- 1979-05-25 JP JP6407279A patent/JPS54154779A/ja active Pending
- 1979-08-08 IE IE889/79A patent/IE49170B1/en unknown

Also Published As

Publication number	Publication date
US4254122A (en)	1981-03-03
NO791722L (no)	1979-11-27
AU4694979A (en)	1979-11-29
ZM4579A1 (en)	1981-05-21
PH14793A (en)	1981-12-09
ATE698T1 (de)	1982-03-15
EP0005911B1 (de)	1982-02-17
IE49170B1 (en)	1985-08-21
ZA792247B (en)	1980-05-28
CS213377B2 (en)	1982-04-09
AU529948B2 (en)	1983-06-30
HU180252B (en)	1983-02-28
DK213179A (da)	1979-11-27
JPS54154779A (en)	1979-12-06
CA1108138A (en)	1981-09-01
DE2962124D1 (en)	1982-03-25
FI66180C (fi)	1984-09-10
FI66180B (fi)	1984-05-31
DD143906A5 (de)	1980-09-17
GR68185B (de)	1981-11-09
ZW9179A1 (en)	1981-01-21
IE790889L (en)	1979-11-26
EP0005911A1 (de)	1979-12-12
ES480932A1 (es)	1980-02-01
IL57324A0 (en)	1979-09-30
FI791670A7 (fi)	1979-11-27
MW1379A1 (en)	1981-04-08
PT69650A (en)	1979-06-01
NZ190402A (en)	1982-05-31

Publication	Publication Date	Title
IL57324A (en)	1983-10-31	3-substituted-6-alkanoylamino-1,3,5-triazine-2,4-diones,process for their preparation and pharmaceutical compositions containing them
NO163956C (no)	1990-08-15	Analogifremgangsmaate til fremstilling av terapeutisk aktive (4-piperidinylmetyl- og -hetero)puriner.
HK86793A (en)	1993-08-27	Indole derivatives
IL74031A0 (en)	1985-04-30	Cyanoguanidinophenyldihydropyridazinone derivatives,their preparation and pharmaceutical compositions containing them
AU3945589A (en)	1990-02-15	Substituted 4-piperidinyl-indol-5-yl-alkyl-sulphonamide derivatives
DK491489A (da)	1990-04-07	Imidazolinderivater samt fremgangsmaade til fremstilling deraf
NO171915C (no)	1993-05-19	Analogifremgangsmaate ved fremstilling av terapeutisk aktive 1-azabicyklo(4.2.0)okt-2-en-derivater
AU1507888A (en)	1988-11-03	New bicyclic compounds, processes for preparation thereof and pharmaceutical composition comprising the same
HU893127D0 (en)	1990-01-28	Process for the preparation of novel spiro-(imidazolidino-naphtaline) derivatives and pharmaceutical compositions containing such compounds as active ingredient
AU557494B2 (en)	1986-12-24	2-substituted-5-arylimidazoles
ES8405409A1 (es)	1984-06-01	Un procedimiento para la preparacion de derivados de b-lactama.
ES8300747A1 (es)	1982-11-01	Procedimiento para la preparacion de derivados de acido in- dolacetico
ES8302719A1 (es)	1982-12-01	Un procedimiento para preparar compuestos de cefem
AU7993982A (en)	1982-08-05	Tetra-peptide
DK22983D0 (da)	1983-01-20	Fremgangsmade til fremstilling af penicillinderivater
MY103509A (en)	1993-06-30	Indole derivatives.