IL59099A - Process for improving the solubility of biologically active compounds in water and/or lower aliphatic alcohols and such new compounds with improved solubility - Google Patents

Process for improving the solubility of biologically active compounds in water and/or lower aliphatic alcohols and such new compounds with improved solubility

Info

Publication number
IL59099A
IL59099A IL59099A IL5909980A IL59099A IL 59099 A IL59099 A IL 59099A IL 59099 A IL59099 A IL 59099A IL 5909980 A IL5909980 A IL 5909980A IL 59099 A IL59099 A IL 59099A
Authority
IL
Israel
Prior art keywords
solubility
improving
water
biologically active
aliphatic alcohols
Prior art date
Application number
IL59099A
Other languages
English (en)
Other versions
IL59099A0 (en
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19792901060 external-priority patent/DE2901060A1/de
Priority claimed from DE19792910356 external-priority patent/DE2910356A1/de
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of IL59099A0 publication Critical patent/IL59099A0/xx
Publication of IL59099A publication Critical patent/IL59099A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/334—Polymers modified by chemical after-treatment with organic compounds containing sulfur
    • C08G65/3348—Polymers modified by chemical after-treatment with organic compounds containing sulfur containing nitrogen in addition to sulfur
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/08—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
    • A01N25/10—Macromolecular compounds
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
    • A01N47/34—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the groups, e.g. biuret; Thio analogues thereof; Urea-aldehyde condensation products
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
    • A01N47/36—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the group >N—CO—N< directly attached to at least one heterocyclic ring; Thio analogues thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
    • A01N47/38—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the group >N—CO—N< where at least one nitrogen atom is part of a heterocyclic ring; Thio analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Plant Pathology (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL59099A 1979-01-12 1980-01-09 Process for improving the solubility of biologically active compounds in water and/or lower aliphatic alcohols and such new compounds with improved solubility IL59099A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19792901060 DE2901060A1 (de) 1979-01-12 1979-01-12 Verfahren zur verbesserung der loeslichkeit biologisch aktiver wirkstoffe in wasser und niederen aliphatischen alkoholen sowie neue verbindungen mit verbesserter loeslichkeit
DE19792910356 DE2910356A1 (de) 1979-03-16 1979-03-16 Verfahren zur verbesserung der loeslichkeit biologisch aktiver wirkstoffe in wasser und niederen aliphatischen alkoholen sowie neue verbindungen mit verbesserter loeslichkeit

Publications (2)

Publication Number Publication Date
IL59099A0 IL59099A0 (en) 1980-05-30
IL59099A true IL59099A (en) 1984-03-30

Family

ID=25777372

Family Applications (1)

Application Number Title Priority Date Filing Date
IL59099A IL59099A (en) 1979-01-12 1980-01-09 Process for improving the solubility of biologically active compounds in water and/or lower aliphatic alcohols and such new compounds with improved solubility

Country Status (7)

Country Link
US (1) US4684728A (da)
EP (1) EP0014263B1 (da)
JP (1) JPS5594337A (da)
BR (1) BR8000192A (da)
DE (1) DE2962754D1 (da)
DK (1) DK13580A (da)
IL (1) IL59099A (da)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4581434A (en) * 1982-09-04 1986-04-08 Bayer Aktiengesellschaft Process for increasing the duration of action of agents for combating pests
DE4017439C2 (de) * 1990-05-30 1994-06-23 Deutsches Krebsforsch Polyethersubstituierte Tumormittel
JPH06506217A (ja) * 1991-03-18 1994-07-14 エンゾン，インコーポレーテッド ポリペプチドまたはグリコポリペプチドとポリマーとのヒドラジン含有結合体
JPH0653222U (ja) * 1992-10-23 1994-07-19 節子 相野谷 トランク・ルームの保冷装置
GB9312853D0 (en) * 1993-06-22 1993-08-04 Euro Celtique Sa Chemical compounds
US5922751A (en) * 1994-06-24 1999-07-13 Euro-Celtique, S.A. Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same
US5591776A (en) * 1994-06-24 1997-01-07 Euro-Celtique, S.A. Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV
DE69531506T2 (de) * 1994-12-13 2004-06-24 Euroceltique S.A. Arylthioxanthine
US6025361A (en) * 1994-12-13 2000-02-15 Euro-Celtique, S.A. Trisubstituted thioxanthines
JP2001523213A (ja) * 1994-12-13 2001-11-20 ユーロ−セルティーク，エス．エイ． 三置換チオキサンチン類
US6166041A (en) * 1995-10-11 2000-12-26 Euro-Celtique, S.A. 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma
US5780462A (en) * 1995-12-27 1998-07-14 American Home Products Corporation Water soluble rapamycin esters
US6075016A (en) * 1996-04-10 2000-06-13 Euro-Celtique S.A. 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity
US6331547B1 (en) 1999-08-18 2001-12-18 American Home Products Corporation Water soluble SDZ RAD esters
PT1210350E (pt) * 1999-08-18 2004-10-29 Wyeth Corp Esteres de sdz-rad soluveis em agua
JP4267326B2 (ja) * 2001-03-23 2009-05-27 エンゾン ファーマシューティカルズ，インコーポレーテッド 置換芳香族酸を用いる抗癌剤プロドラッグ
DK1687378T3 (da) * 2003-11-04 2014-03-03 Suprapolix Bv Fremstilling af supramolekylære polymere indeholdende fire brintbindingsenheder i polymerrygraden
US7754897B2 (en) 2005-06-15 2010-07-13 Cardiome Pharma Corp. Synthetic processes for the preparation of aminocyclohexyl ether compounds
WO2005094897A2 (en) * 2004-04-01 2005-10-13 Cardiome Pharma Corp. Pegylated ion channel modulating compounds
US7705036B2 (en) * 2004-04-01 2010-04-27 Cardiome Pharma Corp. Deuterated aminocyclohexyl ether compounds and processes for preparing same
WO2005113011A2 (en) 2004-04-01 2005-12-01 Cardiome Pharma Corp. Prodrugs of ion channel modulating compounds and uses thereof
WO2006006855A1 (en) * 2004-07-12 2006-01-19 Suprapolix B.V. Supramolecular ionomers
EP1828099B1 (en) * 2004-11-18 2020-01-22 Correvio International Sàrl Synthetic process for aminocyclohexyl ether compounds
ATE532540T1 (de) 2005-05-04 2011-11-15 Suprapolix Bv Modulare bioresorbierbare oder biomedizinische biologisch aktive supramolekulare stoffe
DE102005023588A1 (de) * 2005-05-18 2006-11-23 Grünenthal GmbH Salze substituierter Allophansäureester und deren Verwendung in Arzneimitteln
WO2008063057A2 (en) 2006-11-20 2008-05-29 Suprapolix B.V. Supramolecular polymers from low-melting, easily processable building blocks
US8628789B2 (en) * 2007-03-23 2014-01-14 Suprapolix, B.V. Strong reversible hydrogels
EP2310376B1 (en) * 2008-07-04 2014-11-05 SupraPolix B.V. High flow supramolecular compounds
ES2433235T3 (es) * 2009-11-03 2013-12-10 Bayer Intellectual Property Gmbh Fluorouretanos como aditivos en una formulación de fotopolímero
EP2519559B1 (en) 2009-12-30 2015-07-15 3M Innovative Properties Company Perfluoropolyether-containing compounds with oxalylamino groups
CN102770478B (zh) 2009-12-30 2014-03-12 3M创新有限公司 具有全氟聚醚链段和多个氨基乙二酰胺基的共聚物
CN102695745B (zh) 2009-12-30 2013-11-13 3M创新有限公司 具有全氟聚醚链段和聚二有机硅氧烷链段的共聚物
CN102712758B (zh) 2009-12-30 2014-05-07 3M创新有限公司 制备聚二有机硅氧烷-聚乙二酰胺共聚物的方法
US9006386B2 (en) 2010-11-05 2015-04-14 Suprapolix B.V. Process for the preparation of a supramolecular polymer
WO2021146553A1 (en) * 2020-01-17 2021-07-22 Children's Medical Center Corporation Macromolecular prodrugs for light-emitting diodes and uses thereof
CN119306953A (zh) * 2023-07-14 2025-01-14 宁德时代新能源科技股份有限公司 聚合物、制备方法、分散剂、正极浆料、正极极片、二次电池和用电装置

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2857261A (en) * 1954-04-27 1958-10-21 Monsanto Chemicals Herbicidal sulfoalkyl esters of phenoxyacetates
US4039576A (en) * 1972-03-28 1977-08-02 Ciba-Geigy Corporation Process for the manufacture of alkoxylated N-methylol ureas
CA1023376A (en) * 1972-08-04 1977-12-27 Hermann O. Wirth Hydrophilic and difficultly volatile biocidal triorganometallic compounds
CS179484B1 (en) * 1972-08-18 1977-11-30 Otto Wichterle Method of producing polymeric acrylated or methacrylated carriers of biological active compounds
FR2264522A1 (en) * 1974-03-22 1975-10-17 Rouchy Maurice Vitamin F cpds having surface active properties - comprise linoleic, linolenic and arachidonic acid radical joined via O or N to polyalcohols
US4178427A (en) * 1976-05-05 1979-12-11 Texaco Development Corp. Polyether urea epoxy curing agent
US4154724A (en) * 1976-06-28 1979-05-15 Texaco Development Corp. Polyether polyureides and resinous compositions therefrom
DE2645079A1 (de) * 1976-10-06 1978-04-13 Bayer Ernst Polymere sauerstofftraeger und verfahren zu ihrer herstellung
DE2723248A1 (de) * 1977-05-24 1978-11-30 Bayer Ag Insektizide mittel

Also Published As

Publication number Publication date
DE2962754D1 (en) 1982-06-24
IL59099A0 (en) 1980-05-30
EP0014263A3 (en) 1980-09-17
JPS5594337A (en) 1980-07-17
DK13580A (da) 1980-07-13
US4684728A (en) 1987-08-04
BR8000192A (pt) 1980-10-21
EP0014263A2 (de) 1980-08-20
EP0014263B1 (de) 1982-05-05

Similar Documents

Publication Publication Date Title
IL59099A (en) Process for improving the solubility of biologically active compounds in water and/or lower aliphatic alcohols and such new compounds with improved solubility
YU256480A (en) Process for obtaining the solvate of syn-7-2-(2-amino-4-thiazolyl)-2-methxy-imino-acetamido-3-acetoxymethyl-3-cephem-4-carboxylic acid and the alicyclic ether in solid form
GB2075050B (en) Treatment of organic material in supercritical water
HUT36324A (en) Process for capsulating of non-soluable in water materials
ZA806648B (en) Electrolyzer and process
ZA815317B (en) Stabilized formulation of invermectin in water
BG36073A1 (en) Method for introducing biologically active substances in plants
DE3065077D1 (en) Composition and process for stabilizing soil
ZA766942B (en) Water insoluble biologically active compounds and process for their manufacture
ZA773259B (en) Improvements in or relating to methods for reducing the doses of biologically active substances while maintaining the biological effects
IL48679A0 (en) Process and compositions for the elimination of oxygen dissolved in water
IL57596A (en) Process for the purification and concentration of urokinase
GB2095260B (en) Ubstance and immunoactive composition biologically active substance process for preparing the s0
IL61764A0 (en) Solutions of bormoxynil and ioxynil esters
DE3060689D1 (en) Method of improving the solubility of biologically active agents in water and in lower aliphatic alcohols, and compounds having an improved solubility
IT8024000A0 (it) Procedimento per immettere ossigeno in acque e recipiente per attuare il procedimento.
JPS55107791A (en) Electrolysis tank and method
BR8206111A (pt) Processo e aparelho para promover o crescimento de biomassa e corpo para uso no processo
GB8322234D0 (en) Use of formate esters in dyeing
PT71898A (en) Process for the preparation of omega-lactams in particularcaprolactam
JPS5611722A (en) Water retaining method of plant cultivating bed
JPS5611721A (en) Water retaining method of plant cultivating bed
DE3071238D1 (en) Pickling and tanning process and pickling composition
IT1095077B (it) Procedimento ed impianto per la decatitura di tessuti in pezza
GB2017686B (en) Microorganism and its use in preparing cephamycin c