IL68703A - Sustained release diethylpropion hydrochloride compositions - Google Patents

Sustained release diethylpropion hydrochloride compositions

Info

Publication number: IL68703A
Authority: IL; Israel
Prior art keywords: sustained release; diethylpropion hydrochloride; hydrochloride compositions; diethylpropion; compositions
Prior art date: 1982-05-20

Application number

IL68703A

Other languages

English (en)

Other versions

IL68703A0 (en

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-05-20

Filing date

1983-05-16

Publication date

1986-09-30

1983-05-16 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1983-09-30 Publication of IL68703A0 publication Critical patent/IL68703A0/xx

1986-09-30 Publication of IL68703A publication Critical patent/IL68703A/xx

Links

XHZFHAGIQPYPAM-UHFFFAOYSA-N 3-hydroxy-1-[(4-methoxyphenyl)methyl]piperidin-2-one Chemical compound C1=CC(OC)=CC=C1CN1C(=O)C(O)CCC1 XHZFHAGIQPYPAM-UHFFFAOYSA-N 0.000 title abstract 2
229960005259 diethylpropion hydrochloride Drugs 0.000 title abstract 2
239000000203 mixture Substances 0.000 title abstract 2
238000013268 sustained release Methods 0.000 title abstract 2
239000012730 sustained-release form Substances 0.000 title abstract 2
229940125709 anorectic agent Drugs 0.000 abstract 1
239000002830 appetite depressant Substances 0.000 abstract 1
239000002775 capsule Substances 0.000 abstract 1
238000009472 formulation Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Obesity (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Hematology (AREA)
Diabetes (AREA)
Child & Adolescent Psychology (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

IL68703A 1982-05-20 1983-05-16 Sustained release diethylpropion hydrochloride compositions IL68703A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/379,848 US4421736A (en)	1982-05-20	1982-05-20	Sustained release diethylpropion compositions

Publications (2)

Publication Number	Publication Date
IL68703A0 IL68703A0 (en)	1983-09-30
IL68703A true IL68703A (en)	1986-09-30

Family

ID=23498964

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL68703A IL68703A (en)	1982-05-20	1983-05-16	Sustained release diethylpropion hydrochloride compositions

Country Status (11)

Country	Link
US (1)	US4421736A (de)
EP (1)	EP0095123B1 (de)
JP (1)	JPS58210008A (de)
AT (1)	ATE29215T1 (de)
AU (1)	AU550992B2 (de)
DE (1)	DE3373272D1 (de)
IE (1)	IE55115B1 (de)
IL (1)	IL68703A (de)
NZ (1)	NZ204263A (de)
PH (1)	PH19295A (de)
ZA (1)	ZA833489B (de)

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JPS6143108A (ja) *	1984-08-03	1986-03-01	Nippon Shinyaku Co Ltd	医薬品製剤及びその製造法
HU195729B (en) *	1985-02-05	1988-07-28	Sandoz Ag	Process for producing pharmaceutical compositions containing 9,10-dihydro-ergot-alkaloides
GB8507779D0 (en) *	1985-03-26	1985-05-01	Fujisawa Pharmaceutical Co	Drug carrier
JPH0776172B2 (ja) *	1986-04-16	1995-08-16	藤沢薬品工業株式会社	マトリツクス錠
US4795642A (en) *	1986-05-01	1989-01-03	Pharmacaps, Inc.	Gelatin-encapsulated controlled-release composition
US4708834A (en) *	1986-05-01	1987-11-24	Pharmacaps, Inc.	Preparation of gelatin-encapsulated controlled release composition
NZ260408A (en)	1993-05-10	1996-05-28	Euro Celtique Sa	Controlled release preparation comprising tramadol
US7740881B1 (en)	1993-07-01	2010-06-22	Purdue Pharma Lp	Method of treating humans with opioid formulations having extended controlled release
IL110014A (en) *	1993-07-01	1999-11-30	Euro Celtique Sa	Solid controlled-release oral dosage forms of opioid analgesics
US5879705A (en) *	1993-07-27	1999-03-09	Euro-Celtique S.A.	Sustained release compositions of morphine and a method of preparing pharmaceutical compositions
GB2281697A (en) *	1993-09-14	1995-03-15	Euro Celtique Sa	Laxative compositions in capsules
KR100354702B1 (ko) *	1993-11-23	2002-12-28	유로-셀티크 소시에떼 아노뉨	약학조성물의제조방법및서방형조성물
US5891471A (en) *	1993-11-23	1999-04-06	Euro-Celtique, S.A.	Pharmaceutical multiparticulates
US5843480A (en) *	1994-03-14	1998-12-01	Euro-Celtique, S.A.	Controlled release diamorphine formulation
DE4413350A1 (de) *	1994-04-18	1995-10-19	Basf Ag	Retard-Matrixpellets und Verfahren zu ihrer Herstellung
GB9422154D0 (en) *	1994-11-03	1994-12-21	Euro Celtique Sa	Pharmaceutical compositions and method of producing the same
US5965161A (en) *	1994-11-04	1999-10-12	Euro-Celtique, S.A.	Extruded multi-particulates
FR2745500B1 (fr) *	1996-03-04	1998-04-03	Synthelabo	Formulations pharmaceutiques a liberation prolongee contenant de la mizolastine
US6806294B2 (en)	1998-10-15	2004-10-19	Euro-Celtique S.A.	Opioid analgesic
DE19918325A1 (de)	1999-04-22	2000-10-26	Euro Celtique Sa	Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
US10179130B2 (en)	1999-10-29	2019-01-15	Purdue Pharma L.P.	Controlled release hydrocodone formulations
JP4806507B2 (ja)	1999-10-29	2011-11-02	ユーロ−セルティークエス．エイ．	制御放出ヒドロコドン処方
CN101653411A (zh)	2000-10-30	2010-02-24	欧罗赛铁克股份有限公司	控释氢可酮制剂
US8048917B2 (en)	2005-04-06	2011-11-01	Xenoport, Inc.	Prodrugs of GABA analogs, compositions and uses thereof
US7232924B2 (en) *	2001-06-11	2007-06-19	Xenoport, Inc.	Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
WO2002100347A2 (en) *	2001-06-11	2002-12-19	Xenoport, Inc.	Prodrugs of gaba analogs, compositions and uses thereof
WO2002100344A2 (en) *	2001-06-11	2002-12-19	Xenoport, Inc.	Amino acid conjugates providing for sustained systemic concentrations of gaba analogues
FR2838349B1 (fr) *	2002-04-15	2004-06-25	Laurence Paris	Compositions liquides pour capsules molle a liberation prolongee et leur procede de fabrication
AU2003293423A1 (en)	2002-12-06	2004-06-30	Xenoport, Inc.	Carbidopa prodrugs and uses thereof
US20040162351A1 (en) *	2002-12-11	2004-08-19	Gallop Mark A.	Orally administered dosage forms of fused GABA analog prodrugs having reduced toxicity
MXPA05010515A (es) *	2003-03-31	2006-03-10	Xenoport Inc	Tratamiento o prevencion de sofocos calientes utilizando profarmacos de analogos de gaba.
EP2354120A1 (de)	2003-08-20	2011-08-10	XenoPort, Inc.	Synthese von Acyloxyalkylcarbamat-Prodrugs und Zwischenprodukten davon
KR101140559B1 (ko) *	2003-08-20	2012-07-05	제노포트 인코포레이티드	아실옥시알킬 카르바메이트 프로드러그, 합성 및 사용 방법
CA2537837A1 (en) *	2003-09-11	2005-03-24	Xenoport, Inc.	Treating and/or preventing urinary incontinence using prodrugs of gaba analogs
MXPA06003043A (es) *	2003-09-17	2006-05-31	Xenoport Inc	Tratamiento o prevencion del sindrome piernas inquietas utilizando prodrogas de analogos gaba.
US20060128676A1 (en) *	2004-07-13	2006-06-15	Pharmacofore, Inc.	Compositions of nicotinic agonists and therapeutic agents and methods for treating or preventing diseases or pain
WO2006050471A2 (en) *	2004-11-03	2006-05-11	Xenoport, Inc.	Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use
WO2006050472A2 (en) *	2004-11-03	2006-05-11	Xenoport, Inc.	Acyloxyalkyl carbamate prodrugs of 3-aminopropylphosphonous and -phosphinic acids
EP1811986B1 (de) *	2004-11-04	2014-03-26	XenoPort, Inc.	Orale darreichungsformen von gabapentin-prodrug mit verzögerter freisetzung
WO2007002013A2 (en) *	2005-06-20	2007-01-04	Xenoport, Inc.	Acyloxyalkyl carbamate prodrugs of tranexamic acid, methods of synthesis and use
US7884136B2 (en)	2005-06-27	2011-02-08	Biovail Laboratories International S.R.L.	Modified-release formulations of a bupropion salt
WO2007027476A2 (en) *	2005-08-26	2007-03-08	Xenoport, Inc.	Treating premature ejaculation using gabapentin and pregabalin prodrugs
WO2007140272A2 (en)	2006-05-26	2007-12-06	Pharmacofore, Inc.	Controlled release of phenolic opioids
US20080075771A1 (en) *	2006-07-21	2008-03-27	Vaughn Jason M	Hydrophilic opioid abuse deterrent delivery system using opioid antagonists
WO2008033572A1 (en) *	2006-09-15	2008-03-20	Xenoport, Inc.	Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
WO2008073257A1 (en) *	2006-12-08	2008-06-19	Xenoport, Inc.	Use of prodrugs of gaba analogs for treating diseases
US20090246276A1 (en)	2008-01-28	2009-10-01	Graham Jackson	Pharmaceutical Compositions
US20110060040A1 (en) *	2009-09-04	2011-03-10	Xenoport, Inc.	Uses of acyloxyalkyl carbamate prodrugs of tranexamic acid
EP2621282B1 (de)	2010-09-28	2020-04-15	The Regents of The University of California	Gaba-agonisten zur behandlung von erkrankungen im zusammenhang mit dem stoffwechselsyndrom und gaba-kombinationen zur behandlung oder prophylaxe von diabetes vom typ i
US10335406B2 (en)	2015-10-01	2019-07-02	Elysium Therapeutics, Inc.	Opioid compositions resistant to overdose and abuse
CA2998708C (en)	2015-10-01	2019-09-03	Elysium Therapeutics, Inc.	Polysubunit opioid prodrugs resistant to overdose and abuse
JP7234130B2 (ja)	2017-03-17	2023-03-07	エリージウムセラピューティクス，インコーポレイテッド	過剰摂取および乱用に対して抵抗性のポリサブユニットオピオイドプロドラッグ
AU2018360383A1 (en)	2017-11-02	2020-05-21	Natureceuticals Sdn. Bhd.	Extract of orthosiphon stamineus, formulations, and uses thereof
AU2019271799B2 (en)	2018-05-14	2023-10-12	Xgene Pharmaceutical Inc.	Crystalline forms of 1-(acyloxy)-alkyl carbamate drug conjugates of naproxen and pregabalin

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL226958A (de) *	1957-04-17
US3001910A (en) *	1958-04-16	1961-09-26	Temmler Werke	Anorexigenic propiophenones
US3065143A (en) *	1960-04-19	1962-11-20	Richardson Merrell Inc	Sustained release tablet
US3150043A (en) *	1961-02-23	1964-09-22	Orsymonde	Anorectic composition
US3147187A (en) *	1962-09-10	1964-09-01	Don Hall Lab	Sustained release pharmaceutical
BE640616A (de) *	1962-12-19
NL297631A (de) *	1963-06-03
US3297804A (en) *	1964-05-19	1967-01-10	Ono Pharmaceutical Co	Method of filling hard capsules with granules by the open-mouth-down punching method
CH415963A (de) *	1964-09-04	1966-06-30	Wander Ag Dr A	Masse zur Herstellung von Tabletten mit protrahierter Wirkung
US3427378A (en) *	1965-02-12	1969-02-11	American Cyanamid Co	Sustained release encapsulated formula
US4132753A (en) *	1965-02-12	1979-01-02	American Cyanamid Company	Process for preparing oral sustained release granules
US3374146A (en) *	1966-04-18	1968-03-19	American Cyanamid Co	Sustained release encapsulation
US3492397A (en) *	1967-04-07	1970-01-27	Warner Lambert Pharmaceutical	Sustained release dosage in the pellet form and process thereof
NL6808619A (de) *	1968-06-19	1969-12-23
CH630257A5 (en) *	1975-03-17	1982-06-15	Hoffmann La Roche	Sustained release formulation
ZA765931B (en) *	1975-10-10	1977-09-28	Squibb & Sons Inc	Controlled release tablet
US4126672A (en) *	1976-02-04	1978-11-21	Hoffmann-La Roche Inc.	Sustained release pharmaceutical capsules

1982
- 1982-05-20 US US06/379,848 patent/US4421736A/en not_active Expired - Lifetime
1983
- 1983-05-16 ZA ZA833489A patent/ZA833489B/xx unknown
- 1983-05-16 JP JP58084292A patent/JPS58210008A/ja active Pending
- 1983-05-16 PH PH28908A patent/PH19295A/en unknown
- 1983-05-16 IL IL68703A patent/IL68703A/xx not_active IP Right Cessation
- 1983-05-17 DE DE8383104832T patent/DE3373272D1/de not_active Expired
- 1983-05-17 EP EP83104832A patent/EP0095123B1/de not_active Expired
- 1983-05-17 AT AT83104832T patent/ATE29215T1/de not_active IP Right Cessation
- 1983-05-17 NZ NZ204263A patent/NZ204263A/en unknown
- 1983-05-17 AU AU14617/83A patent/AU550992B2/en not_active Expired
- 1983-05-18 IE IE1172/83A patent/IE55115B1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
IL68703A0 (en)	1983-09-30
AU550992B2 (en)	1986-04-10
IE831172L (en)	1983-11-20
PH19295A (en)	1986-03-05
US4421736A (en)	1983-12-20
DE3373272D1 (en)	1987-10-08
EP0095123A3 (en)	1984-12-12
AU1461783A (en)	1983-11-24
JPS58210008A (ja)	1983-12-07
EP0095123A2 (de)	1983-11-30
NZ204263A (en)	1986-02-21
EP0095123B1 (de)	1987-09-02
ZA833489B (en)	1984-02-29
IE55115B1 (en)	1990-06-06
ATE29215T1 (de)	1987-09-15

Legal Events

Date	Code	Title	Description
1997-08-14	KB	Patent renewed
2001-07-24	KB20	Patent renewed for 20 years
2003-07-31	EXP	Patent expired
2006-09-05	HC	Change of name of proprietor(s)	Owner name: AVENTIS INC. Free format text: FORMER NAME:MERRELL PHARMACEUTICALS INC.

Publication	Publication Date	Title
DE3373272D1 (en)	1987-10-08	Sustained release diethylpropion compositions
GB2117239B (en)	1987-03-11	Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
IL112637A0 (en)	1995-05-26	A pharmaceutical composition containing oxybutynin and methods for the preparation thereof
ES519423A0 (es)	1985-04-16	Procedimiento para preparar 9-(1 o 3-monoaciloxi-o 1,3-diaciloxi-2-propoximetil)-purinas substituidas en calidad de agentes antiviricos.
GB2056278B (en)	1983-06-29	Sustained release compositions
IL58279A0 (en)	1979-12-30	Sustained release pharmaceutical compositions
GB2053682B (en)	1983-10-12	Sustained release pharmaceutical compositions
IL67497A0 (en)	1983-05-15	Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
IT8320775A0 (it)	1983-04-22	Composizioni poliuretaniche a base acquosa e procedimento per la loro preparazione.
IT8322616A0 (it)	1983-08-23	Composizione per agenti antitumorali.
EP0114878A4 (de)	1986-03-18	Phthalazin substituierte aminomethylbenzolabkömmlinge, zusammensetzungen und verwendung.
DE3887839D1 (de)	1994-03-24	Trennmittelzusammensetzung.
ZA922297B (en)	1992-12-30	Crystalline tiababine monohydrate,its preparation and use
MY100900A (en)	1991-05-16	Substituted phenylsulfonyloxybenzimidazolecarbamates, processes for their preparation and their use as medicaments.
JPS53105477A (en)	1978-09-13	7-glycylprolylamono-4-methylcoumarine
ES8501750A1 (es)	1984-12-01	Un procedimiento para la preparacion de 4-aril-4-piperidincarbinoles.
AU8111282A (en)	1982-09-16	1,2,3,6 tetrahydropyridines as anorectic agents
IL69599A0 (en)	1983-11-30	Tert.-butanol derivatives,their preparation and antimycotic agents containing them
DE3278126D1 (en)	1988-03-31	Sustained release compositions
BG38936A3 (en)	1986-03-14	Means for protection from helminths
ZA836298B (en)	1984-09-26	Anthelmintic compositions
AP2000001746A0 (en)	2000-03-31	Anti- first-pass effect compounds.
JPS5250481A (en)	1977-04-22	Air cylinder
AU1734183A (en)	1984-02-02	3alpha-(substituted-phenyl)-3alpah,4,7,7alpha-tetrahydro-4, 7-methanoisoindolines
AU4015778A (en)	1980-04-03	2',6'-dihydroxy-9-(2,5-dihydroxy-9-(2,5-dihydroxypeny)-octylpheneone as an anti-oxidant