IL68703A - Sustained release diethylpropion hydrochloride compositions - Google Patents

Sustained release diethylpropion hydrochloride compositions

Info

Publication number: IL68703A
Authority: IL; Israel
Prior art keywords: sustained release; diethylpropion hydrochloride; hydrochloride compositions; diethylpropion; compositions
Prior art date: 1982-05-20

Application number

IL68703A

Other languages

English (en)

Other versions

IL68703A0 (en

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-05-20

Filing date

1983-05-16

Publication date

1986-09-30

1983-05-16 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1983-09-30 Publication of IL68703A0 publication Critical patent/IL68703A0/xx

1986-09-30 Publication of IL68703A publication Critical patent/IL68703A/xx

Links

XHZFHAGIQPYPAM-UHFFFAOYSA-N 3-hydroxy-1-[(4-methoxyphenyl)methyl]piperidin-2-one Chemical compound C1=CC(OC)=CC=C1CN1C(=O)C(O)CCC1 XHZFHAGIQPYPAM-UHFFFAOYSA-N 0.000 title abstract 2
229960005259 diethylpropion hydrochloride Drugs 0.000 title abstract 2
239000000203 mixture Substances 0.000 title abstract 2
238000013268 sustained release Methods 0.000 title abstract 2
239000012730 sustained-release form Substances 0.000 title abstract 2
229940125709 anorectic agent Drugs 0.000 abstract 1
239000002830 appetite depressant Substances 0.000 abstract 1
239000002775 capsule Substances 0.000 abstract 1
238000009472 formulation Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Obesity (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Hematology (AREA)
Diabetes (AREA)
Child & Adolescent Psychology (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

IL68703A 1982-05-20 1983-05-16 Sustained release diethylpropion hydrochloride compositions IL68703A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/379,848 US4421736A (en)	1982-05-20	1982-05-20	Sustained release diethylpropion compositions

Publications (2)

Publication Number	Publication Date
IL68703A0 IL68703A0 (en)	1983-09-30
IL68703A true IL68703A (en)	1986-09-30

Family

ID=23498964

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL68703A IL68703A (en)	1982-05-20	1983-05-16	Sustained release diethylpropion hydrochloride compositions

Country Status (11)

Country	Link
US (1)	US4421736A (de)
EP (1)	EP0095123B1 (de)
JP (1)	JPS58210008A (de)
AT (1)	ATE29215T1 (de)
AU (1)	AU550992B2 (de)
DE (1)	DE3373272D1 (de)
IE (1)	IE55115B1 (de)
IL (1)	IL68703A (de)
NZ (1)	NZ204263A (de)
PH (1)	PH19295A (de)
ZA (1)	ZA833489B (de)

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JPS6143108A (ja) *	1984-08-03	1986-03-01	Nippon Shinyaku Co Ltd	医薬品製剤及びその製造法
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JPH0776172B2 (ja) *	1986-04-16	1995-08-16	藤沢薬品工業株式会社	マトリツクス錠
US4708834A (en) *	1986-05-01	1987-11-24	Pharmacaps, Inc.	Preparation of gelatin-encapsulated controlled release composition
US4795642A (en) *	1986-05-01	1989-01-03	Pharmacaps, Inc.	Gelatin-encapsulated controlled-release composition
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US7740881B1 (en)	1993-07-01	2010-06-22	Purdue Pharma Lp	Method of treating humans with opioid formulations having extended controlled release
IL110014A (en) *	1993-07-01	1999-11-30	Euro Celtique Sa	Solid controlled-release oral dosage forms of opioid analgesics
US5879705A (en) *	1993-07-27	1999-03-09	Euro-Celtique S.A.	Sustained release compositions of morphine and a method of preparing pharmaceutical compositions
GB2281697A (en) *	1993-09-14	1995-03-15	Euro Celtique Sa	Laxative compositions in capsules
KR100354702B1 (ko) *	1993-11-23	2002-12-28	유로-셀티크 소시에떼 아노뉨	약학조성물의제조방법및서방형조성물
US5891471A (en) *	1993-11-23	1999-04-06	Euro-Celtique, S.A.	Pharmaceutical multiparticulates
US5843480A (en) *	1994-03-14	1998-12-01	Euro-Celtique, S.A.	Controlled release diamorphine formulation
DE4413350A1 (de) *	1994-04-18	1995-10-19	Basf Ag	Retard-Matrixpellets und Verfahren zu ihrer Herstellung
GB9422154D0 (en) *	1994-11-03	1994-12-21	Euro Celtique Sa	Pharmaceutical compositions and method of producing the same
US5965161A (en) *	1994-11-04	1999-10-12	Euro-Celtique, S.A.	Extruded multi-particulates
FR2745500B1 (fr) *	1996-03-04	1998-04-03	Synthelabo	Formulations pharmaceutiques a liberation prolongee contenant de la mizolastine
US6806294B2 (en)	1998-10-15	2004-10-19	Euro-Celtique S.A.	Opioid analgesic
DE19918325A1 (de)	1999-04-22	2000-10-26	Euro Celtique Sa	Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
KR100889069B1 (ko)	1999-10-29	2009-03-17	유로-셀티크 소시에떼 아노뉨	서방성 하이드로코돈 제형
US10179130B2 (en)	1999-10-29	2019-01-15	Purdue Pharma L.P.	Controlled release hydrocodone formulations
AU2738302A (en)	2000-10-30	2002-05-15	Euro Celtique Sa	Controlled release hydrocodone formulations
AU2002345638A1 (en) *	2001-06-11	2002-12-23	Xenoport, Inc.	Amino acid conjugates providing for sustained systemic concentrations of gaba analogues
US8048917B2 (en)	2005-04-06	2011-11-01	Xenoport, Inc.	Prodrugs of GABA analogs, compositions and uses thereof
US7232924B2 (en) *	2001-06-11	2007-06-19	Xenoport, Inc.	Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
CA2449729C (en) *	2001-06-11	2009-11-03	Xenoport, Inc.	Prodrugs of gaba analogs, compositions and uses thereof
FR2838349B1 (fr) *	2002-04-15	2004-06-25	Laurence Paris	Compositions liquides pour capsules molle a liberation prolongee et leur procede de fabrication
US7101912B2 (en)	2002-12-06	2006-09-05	Xenoport, Inc.	Carbidopa prodrugs and derivatives, and compositions and uses thereof
US20040162351A1 (en) *	2002-12-11	2004-08-19	Gallop Mark A.	Orally administered dosage forms of fused GABA analog prodrugs having reduced toxicity
KR20050119676A (ko) *	2003-03-31	2005-12-21	제노포트 인코포레이티드	가바 유사체의 프로드러그를 사용한 열성 홍조의 치료 또는예방
EP2354120A1 (de)	2003-08-20	2011-08-10	XenoPort, Inc.	Synthese von Acyloxyalkylcarbamat-Prodrugs und Zwischenprodukten davon
BRPI0413756A (pt) *	2003-08-20	2006-10-31	Xenoport Inc	composto, métodos para tratar ou evitar espasticidade ou um sintoma de espasticidade, doença de refluxo gastro-esofágico, vìcio em droga, vìcio em ou abuso de álcool, ou vìcio em ou abuso de nicotina, e tosse ou êmese em um paciente, e, composição farmacêutica
KR20060119971A (ko) *	2003-09-11	2006-11-24	제노포트 인코포레이티드	Ｇａｂａ 유사체의 전구약물을 이용한 요실금의 치료및/또는 예방
NZ579515A (en) *	2003-09-17	2011-09-30	Xenoport Inc	Treating or preventing restless legs syndrome using prodrugs of gaba analogs
US20060128676A1 (en) *	2004-07-13	2006-06-15	Pharmacofore, Inc.	Compositions of nicotinic agonists and therapeutic agents and methods for treating or preventing diseases or pain
US7566738B2 (en) *	2004-11-03	2009-07-28	Xenoport, Inc.	Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use
US7494985B2 (en) *	2004-11-03	2009-02-24	Xenoport, Inc.	Acyloxyalkyl carbamate prodrugs, methods of synthesis, and use
MX2007005306A (es) *	2004-11-04	2007-06-11	Xenoport Inc	Formas de dosis oral de liberacion sostenida de la prodroga gabapentina.
US7351740B2 (en)	2005-06-20	2008-04-01	Xenoport, Inc.	Acyloxyalkyl carbamate prodrugs of tranexamic acid, methods of synthesis and use
ZA200711123B (en)	2005-06-27	2009-08-26	Biovail Lab Int Srl	Modified-release formulations of a bupropion salt
WO2007027476A2 (en) *	2005-08-26	2007-03-08	Xenoport, Inc.	Treating premature ejaculation using gabapentin and pregabalin prodrugs
MX2008014794A (es)	2006-05-26	2009-04-08	Pharmacofore Inc	Liberacion controlada de opioides fenolicos.
US20080075768A1 (en) *	2006-07-21	2008-03-27	Vaughn Jason M	Hydrophobic opioid abuse deterrent delivery system using opioid antagonists
US7585996B2 (en) *	2006-09-15	2009-09-08	Xenoport, Inc.	Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
US20080161393A1 (en) *	2006-12-08	2008-07-03	Barrett Ronald W	Use of prodrugs of GABA analogs for treating disease
US20090246276A1 (en)	2008-01-28	2009-10-01	Graham Jackson	Pharmaceutical Compositions
WO2011028234A1 (en) *	2009-09-04	2011-03-10	Xenoport, Inc.	Uses of acyloxyalkyl carbamate prodrugs of tranexamic acid
DK2621282T3 (da)	2010-09-28	2020-05-04	Univ California	Gaba-agonister i behandlingen af forstyrrelser forbundet med metabolisk syndrom og gaba-kombinationer i behandling eller profylakse af type i diabetes
AU2016332071B2 (en)	2015-10-01	2019-04-18	Elysium Therapeutics, Inc.	Polysubunit opioid prodrugs resistant to overdose and abuse
US10335406B2 (en)	2015-10-01	2019-07-02	Elysium Therapeutics, Inc.	Opioid compositions resistant to overdose and abuse
EP3595663A4 (de)	2017-03-17	2021-01-13	Elysium Therapeutics, Inc.	Mehrfachuntereinheit-opioid-prodrugs mit resistenz gegen überdosierung und missbrauch
WO2019087084A1 (en)	2017-11-02	2019-05-09	Eman Biodiscoveries Sd. Bhd.	Extract of orthosiphon stamineus, formulations, and uses thereof
CA3099775A1 (en)	2018-05-14	2019-11-21	Xgene Pharmaceutical Inc.	Process for making 1-(acyloxy)-alkyl-carabmate drug conjugates of naproxen and pregabalin

Family Cites Families (17)

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Publication number	Priority date	Publication date	Assignee	Title
NL101341C (de) *	1957-04-17
US3001910A (en) *	1958-04-16	1961-09-26	Temmler Werke	Anorexigenic propiophenones
US3065143A (en) *	1960-04-19	1962-11-20	Richardson Merrell Inc	Sustained release tablet
US3150043A (en) *	1961-02-23	1964-09-22	Orsymonde	Anorectic composition
US3147187A (en) *	1962-09-10	1964-09-01	Don Hall Lab	Sustained release pharmaceutical
BE640616A (de) *	1962-12-19
NL297631A (de) *	1963-06-03
US3297804A (en) *	1964-05-19	1967-01-10	Ono Pharmaceutical Co	Method of filling hard capsules with granules by the open-mouth-down punching method
CH415963A (de) *	1964-09-04	1966-06-30	Wander Ag Dr A	Masse zur Herstellung von Tabletten mit protrahierter Wirkung
US4132753A (en) *	1965-02-12	1979-01-02	American Cyanamid Company	Process for preparing oral sustained release granules
US3427378A (en) *	1965-02-12	1969-02-11	American Cyanamid Co	Sustained release encapsulated formula
US3374146A (en) *	1966-04-18	1968-03-19	American Cyanamid Co	Sustained release encapsulation
US3492397A (en) *	1967-04-07	1970-01-27	Warner Lambert Pharmaceutical	Sustained release dosage in the pellet form and process thereof
SE335202B (de) *	1968-06-19	1971-05-17	Aco Laekemedel Ab
CH630257A5 (en) *	1975-03-17	1982-06-15	Hoffmann La Roche	Sustained release formulation
GB1568837A (en) *	1975-10-10	1980-06-04	Squibb & Sons Inc	Controlled release tablet
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1982
- 1982-05-20 US US06/379,848 patent/US4421736A/en not_active Expired - Lifetime
1983
- 1983-05-16 ZA ZA833489A patent/ZA833489B/xx unknown
- 1983-05-16 IL IL68703A patent/IL68703A/xx not_active IP Right Cessation
- 1983-05-16 JP JP58084292A patent/JPS58210008A/ja active Pending
- 1983-05-16 PH PH28908A patent/PH19295A/en unknown
- 1983-05-17 NZ NZ204263A patent/NZ204263A/en unknown
- 1983-05-17 AT AT83104832T patent/ATE29215T1/de not_active IP Right Cessation
- 1983-05-17 EP EP83104832A patent/EP0095123B1/de not_active Expired
- 1983-05-17 DE DE8383104832T patent/DE3373272D1/de not_active Expired
- 1983-05-17 AU AU14617/83A patent/AU550992B2/en not_active Expired
- 1983-05-18 IE IE1172/83A patent/IE55115B1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU550992B2 (en)	1986-04-10
EP0095123B1 (de)	1987-09-02
JPS58210008A (ja)	1983-12-07
ZA833489B (en)	1984-02-29
DE3373272D1 (en)	1987-10-08
PH19295A (en)	1986-03-05
ATE29215T1 (de)	1987-09-15
IE55115B1 (en)	1990-06-06
EP0095123A2 (de)	1983-11-30
US4421736A (en)	1983-12-20
IE831172L (en)	1983-11-20
AU1461783A (en)	1983-11-24
EP0095123A3 (en)	1984-12-12
NZ204263A (en)	1986-02-21
IL68703A0 (en)	1983-09-30

Legal Events

Date	Code	Title	Description
1997-08-14	KB	Patent renewed
2001-07-24	KB20	Patent renewed for 20 years
2003-07-31	EXP	Patent expired
2006-09-05	HC	Change of name of proprietor(s)	Owner name: AVENTIS INC. Free format text: FORMER NAME:MERRELL PHARMACEUTICALS INC.

Publication	Publication Date	Title
DE3373272D1 (en)	1987-10-08	Sustained release diethylpropion compositions
GB2117239B (en)	1987-03-11	Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
ES519423A0 (es)	1985-04-16	Procedimiento para preparar 9-(1 o 3-monoaciloxi-o 1,3-diaciloxi-2-propoximetil)-purinas substituidas en calidad de agentes antiviricos.
GB2056278B (en)	1983-06-29	Sustained release compositions
IL58279A0 (en)	1979-12-30	Sustained release pharmaceutical compositions
GB2053682B (en)	1983-10-12	Sustained release pharmaceutical compositions
IL67497A0 (en)	1983-05-15	Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
IT8320775A0 (it)	1983-04-22	Composizioni poliuretaniche a base acquosa e procedimento per la loro preparazione.
GR3035585T3 (en)	2001-06-29	Polymer film compositions for capsules
TR199800077T1 (xx)	1998-05-21	Kontroll� ��z�len paroksetin terkipleri.
IT8322616A0 (it)	1983-08-23	Composizione per agenti antitumorali.
DE3887839D1 (de)	1994-03-24	Trennmittelzusammensetzung.
ZA922297B (en)	1992-12-30	Crystalline tiababine monohydrate,its preparation and use
MY100900A (en)	1991-05-16	Substituted phenylsulfonyloxybenzimidazolecarbamates, processes for their preparation and their use as medicaments.
MX9200731A (es)	1992-09-01	Compuestos de hidrazona, procedimientos para su prcompuestos de hidrazona, procedimientos para su preparacion, compuestos intermedios utiles para su oeparacion, compuestos intermedios utiles para suobtencion y composiciones pesticidas que contienena btencion y composiciones pesticidas que contienenalos mismos. los mismos.
ES8501750A1 (es)	1984-12-01	Un procedimiento para la preparacion de 4-aril-4-piperidincarbinoles.
JPS5332124A (en)	1978-03-27	Carcinostatic agent
DE3278126D1 (en)	1988-03-31	Sustained release compositions
ZA836298B (en)	1984-09-26	Anthelmintic compositions
ZA804421B (en)	1981-09-30	Substituted-1,2,3-thiadiazole-safening agents
JPS5250481A (en)	1977-04-22	Air cylinder
AU4015778A (en)	1980-04-03	2',6'-dihydroxy-9-(2,5-dihydroxy-9-(2,5-dihydroxypeny)-octylpheneone as an anti-oxidant
ES532109A0 (es)	1985-06-16	Procedimiento para preparar 9-(1 o 3-monoaciloxi-o 1,3-diaciloxi-2-propoximetil)-purinas substituidas en calidad de agentes antiviricos.
IT8220526A0 (it)	1982-04-01	Composizioni acaricide.
DE3360323D1 (en)	1985-08-01	Trimethylbicyclo(4.3.0)non-1-ene derivatives, their preparation and use as perfumes, and the perfumed compositions containing them