IL68703A - Sustained release diethylpropion hydrochloride compositions - Google Patents

Sustained release diethylpropion hydrochloride compositions

Info

Publication number: IL68703A
Authority: IL; Israel
Prior art keywords: sustained release; diethylpropion hydrochloride; hydrochloride compositions; diethylpropion; compositions
Prior art date: 1982-05-20

Application number

IL68703A

Other languages

English (en)

Other versions

IL68703A0 (en

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-05-20

Filing date

1983-05-16

Publication date

1986-09-30

1983-05-16 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1983-09-30 Publication of IL68703A0 publication Critical patent/IL68703A0/xx

1986-09-30 Publication of IL68703A publication Critical patent/IL68703A/xx

Links

XHZFHAGIQPYPAM-UHFFFAOYSA-N 3-hydroxy-1-[(4-methoxyphenyl)methyl]piperidin-2-one Chemical compound C1=CC(OC)=CC=C1CN1C(=O)C(O)CCC1 XHZFHAGIQPYPAM-UHFFFAOYSA-N 0.000 title abstract 2
229960005259 diethylpropion hydrochloride Drugs 0.000 title abstract 2
239000000203 mixture Substances 0.000 title abstract 2
238000013268 sustained release Methods 0.000 title abstract 2
239000012730 sustained-release form Substances 0.000 title abstract 2
229940125709 anorectic agent Drugs 0.000 abstract 1
239000002830 appetite depressant Substances 0.000 abstract 1
239000002775 capsule Substances 0.000 abstract 1
238000009472 formulation Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Obesity (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Hematology (AREA)
Diabetes (AREA)
Child & Adolescent Psychology (AREA)
Medicinal Preparation (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

IL68703A 1982-05-20 1983-05-16 Sustained release diethylpropion hydrochloride compositions IL68703A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/379,848 US4421736A (en)	1982-05-20	1982-05-20	Sustained release diethylpropion compositions

Publications (2)

Publication Number	Publication Date
IL68703A0 IL68703A0 (en)	1983-09-30
IL68703A true IL68703A (en)	1986-09-30

Family

ID=23498964

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL68703A IL68703A (en)	1982-05-20	1983-05-16	Sustained release diethylpropion hydrochloride compositions

Country Status (11)

Country	Link
US (1)	US4421736A (de)
EP (1)	EP0095123B1 (de)
JP (1)	JPS58210008A (de)
AT (1)	ATE29215T1 (de)
AU (1)	AU550992B2 (de)
DE (1)	DE3373272D1 (de)
IE (1)	IE55115B1 (de)
IL (1)	IL68703A (de)
NZ (1)	NZ204263A (de)
PH (1)	PH19295A (de)
ZA (1)	ZA833489B (de)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6143108A (ja) *	1984-08-03	1986-03-01	Nippon Shinyaku Co Ltd	医薬品製剤及びその製造法
NL8600161A (nl) *	1985-02-05	1986-09-01	Sandoz Ag	Farmaceutische preparaten die 9,10-dihydroergotalkaloiden bevatten.
GB8507779D0 (en) *	1985-03-26	1985-05-01	Fujisawa Pharmaceutical Co	Drug carrier
JPH0776172B2 (ja) *	1986-04-16	1995-08-16	藤沢薬品工業株式会社	マトリツクス錠
US4708834A (en) *	1986-05-01	1987-11-24	Pharmacaps, Inc.	Preparation of gelatin-encapsulated controlled release composition
US4795642A (en) *	1986-05-01	1989-01-03	Pharmacaps, Inc.	Gelatin-encapsulated controlled-release composition
NZ260408A (en) *	1993-05-10	1996-05-28	Euro Celtique Sa	Controlled release preparation comprising tramadol
IL110014A (en) *	1993-07-01	1999-11-30	Euro Celtique Sa	Solid controlled-release oral dosage forms of opioid analgesics
US7740881B1 (en)	1993-07-01	2010-06-22	Purdue Pharma Lp	Method of treating humans with opioid formulations having extended controlled release
US5879705A (en) *	1993-07-27	1999-03-09	Euro-Celtique S.A.	Sustained release compositions of morphine and a method of preparing pharmaceutical compositions
GB2281697A (en) *	1993-09-14	1995-03-15	Euro Celtique Sa	Laxative compositions in capsules
KR100354702B1 (ko) *	1993-11-23	2002-12-28	유로-셀티크 소시에떼 아노뉨	약학조성물의제조방법및서방형조성물
US5891471A (en) *	1993-11-23	1999-04-06	Euro-Celtique, S.A.	Pharmaceutical multiparticulates
US5843480A (en) *	1994-03-14	1998-12-01	Euro-Celtique, S.A.	Controlled release diamorphine formulation
DE4413350A1 (de) *	1994-04-18	1995-10-19	Basf Ag	Retard-Matrixpellets und Verfahren zu ihrer Herstellung
GB9422154D0 (en) *	1994-11-03	1994-12-21	Euro Celtique Sa	Pharmaceutical compositions and method of producing the same
US5965161A (en) *	1994-11-04	1999-10-12	Euro-Celtique, S.A.	Extruded multi-particulates
FR2745500B1 (fr) *	1996-03-04	1998-04-03	Synthelabo	Formulations pharmaceutiques a liberation prolongee contenant de la mizolastine
US6806294B2 (en)	1998-10-15	2004-10-19	Euro-Celtique S.A.	Opioid analgesic
DE19918325A1 (de)	1999-04-22	2000-10-26	Euro Celtique Sa	Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
EP2295043A1 (de)	1999-10-29	2011-03-16	Euro-Celtique S.A.	Hydrocodon-Formulierungen mit gesteuerter Freisetzung
US10179130B2 (en)	1999-10-29	2019-01-15	Purdue Pharma L.P.	Controlled release hydrocodone formulations
AU2002227383B2 (en)	2000-10-30	2004-07-08	Euro-Celtique S.A.	Controlled release hydrocodone formulations
US7232924B2 (en) *	2001-06-11	2007-06-19	Xenoport, Inc.	Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
EP1412324A4 (de) *	2001-06-11	2004-09-29	Xenoport Inc	Aminosäurekonjugate, die anhaltende systemische konzentrationen von gaba-analoga ergeben
AU2002310409C1 (en) *	2001-06-11	2008-04-17	Xenoport, Inc.	Orally administered dosage forms of GABA analog prodrugs having reduced toxicity
US8048917B2 (en)	2005-04-06	2011-11-01	Xenoport, Inc.	Prodrugs of GABA analogs, compositions and uses thereof
FR2838349B1 (fr) *	2002-04-15	2004-06-25	Laurence Paris	Compositions liquides pour capsules molle a liberation prolongee et leur procede de fabrication
AU2003293423A1 (en)	2002-12-06	2004-06-30	Xenoport, Inc.	Carbidopa prodrugs and uses thereof
AU2003297909A1 (en) *	2002-12-11	2004-06-30	Xenoport, Inc.	Orally administered dosage forms of fused gaba analog prodrugs having reduced toxicity
MXPA05010515A (es) *	2003-03-31	2006-03-10	Xenoport Inc	Tratamiento o prevencion de sofocos calientes utilizando profarmacos de analogos de gaba.
AU2004267100B2 (en)	2003-08-20	2010-10-07	Xenoport, Inc.	Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
EP2354120A1 (de)	2003-08-20	2011-08-10	XenoPort, Inc.	Synthese von Acyloxyalkylcarbamat-Prodrugs und Zwischenprodukten davon
CA2537837A1 (en) *	2003-09-11	2005-03-24	Xenoport, Inc.	Treating and/or preventing urinary incontinence using prodrugs of gaba analogs
CA2538802C (en) *	2003-09-17	2015-01-27	Xenoport, Inc.	Treating or preventing restless legs syndrome using prodrugs of gaba analogs
US20060128676A1 (en) *	2004-07-13	2006-06-15	Pharmacofore, Inc.	Compositions of nicotinic agonists and therapeutic agents and methods for treating or preventing diseases or pain
US7494985B2 (en) *	2004-11-03	2009-02-24	Xenoport, Inc.	Acyloxyalkyl carbamate prodrugs, methods of synthesis, and use
US7566738B2 (en) *	2004-11-03	2009-07-28	Xenoport, Inc.	Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use
EP1811986B1 (de) *	2004-11-04	2014-03-26	XenoPort, Inc.	Orale darreichungsformen von gabapentin-prodrug mit verzögerter freisetzung
EP1919859B1 (de)	2005-06-20	2010-06-02	Xenoport, Inc.	Acyloxyalkylcarbamat-prodrugs von tranexansäure und anwendung
US7241805B2 (en)	2005-06-27	2007-07-10	Biovail Laboratories, Inc.	Modified release formulations of a bupropion salt
WO2007027476A2 (en) *	2005-08-26	2007-03-08	Xenoport, Inc.	Treating premature ejaculation using gabapentin and pregabalin prodrugs
SG172633A1 (en)	2006-05-26	2011-07-28	Pharmacofore Inc	Controlled release of phenolic opioids
CA2671197A1 (en) *	2006-07-21	2008-01-24	Lab International Srl	Hydrophobic abuse deterrent delivery system
WO2008033572A1 (en) *	2006-09-15	2008-03-20	Xenoport, Inc.	Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
CA2672044A1 (en) *	2006-12-08	2008-06-19	Xenoport, Inc.	Use of prodrugs of gaba analogs for treating diseases
US20090246276A1 (en)	2008-01-28	2009-10-01	Graham Jackson	Pharmaceutical Compositions
WO2011028234A1 (en) *	2009-09-04	2011-03-10	Xenoport, Inc.	Uses of acyloxyalkyl carbamate prodrugs of tranexamic acid
CN107050456B (zh)	2010-09-28	2022-08-12	加利福尼亚大学董事会	治疗代谢综合征相关疾病的gaba激动剂和治疗或预防i型糖尿病的gaba组合
WO2017059459A1 (en)	2015-10-01	2017-04-06	Elysium Therapeutics, Inc.	Polysubunit opioid prodrugs resistant to overdose and abuse
US10335406B2 (en)	2015-10-01	2019-07-02	Elysium Therapeutics, Inc.	Opioid compositions resistant to overdose and abuse
CA3056239C (en)	2017-03-17	2023-09-12	Elysium Therapeutics, Inc.	Polysubunit opioid prodrugs resistant to overdose and abuse
AU2018360383A1 (en)	2017-11-02	2020-05-21	Natureceuticals Sdn. Bhd.	Extract of orthosiphon stamineus, formulations, and uses thereof
JP7441181B2 (ja)	2018-05-14	2024-02-29	エックスジーンファーマシューティカルインク．	ナプロキセンとプレガバリンの１－（アシルオキシ）－アルキルカルバメート薬品複合体の結晶形態

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL101341C (de) *	1957-04-17
US3001910A (en) *	1958-04-16	1961-09-26	Temmler Werke	Anorexigenic propiophenones
US3065143A (en) *	1960-04-19	1962-11-20	Richardson Merrell Inc	Sustained release tablet
US3150043A (en) *	1961-02-23	1964-09-22	Orsymonde	Anorectic composition
US3147187A (en) *	1962-09-10	1964-09-01	Don Hall Lab	Sustained release pharmaceutical
BE640616A (de) *	1962-12-19
NL297631A (de) *	1963-06-03
US3297804A (en) *	1964-05-19	1967-01-10	Ono Pharmaceutical Co	Method of filling hard capsules with granules by the open-mouth-down punching method
CH415963A (de) *	1964-09-04	1966-06-30	Wander Ag Dr A	Masse zur Herstellung von Tabletten mit protrahierter Wirkung
US3427378A (en) *	1965-02-12	1969-02-11	American Cyanamid Co	Sustained release encapsulated formula
US4132753A (en) *	1965-02-12	1979-01-02	American Cyanamid Company	Process for preparing oral sustained release granules
US3374146A (en) *	1966-04-18	1968-03-19	American Cyanamid Co	Sustained release encapsulation
US3492397A (en) *	1967-04-07	1970-01-27	Warner Lambert Pharmaceutical	Sustained release dosage in the pellet form and process thereof
NL6808619A (de) *	1968-06-19	1969-12-23
CH630257A5 (en) *	1975-03-17	1982-06-15	Hoffmann La Roche	Sustained release formulation
CA1097220A (en) *	1975-10-10	1981-03-10	Aaron L. Weiss	Controlled release tablet
US4126672A (en) *	1976-02-04	1978-11-21	Hoffmann-La Roche Inc.	Sustained release pharmaceutical capsules

1982
- 1982-05-20 US US06/379,848 patent/US4421736A/en not_active Expired - Lifetime
1983
- 1983-05-16 JP JP58084292A patent/JPS58210008A/ja active Pending
- 1983-05-16 IL IL68703A patent/IL68703A/xx not_active IP Right Cessation
- 1983-05-16 PH PH28908A patent/PH19295A/en unknown
- 1983-05-16 ZA ZA833489A patent/ZA833489B/xx unknown
- 1983-05-17 EP EP83104832A patent/EP0095123B1/de not_active Expired
- 1983-05-17 NZ NZ204263A patent/NZ204263A/en unknown
- 1983-05-17 AU AU14617/83A patent/AU550992B2/en not_active Expired
- 1983-05-17 AT AT83104832T patent/ATE29215T1/de not_active IP Right Cessation
- 1983-05-17 DE DE8383104832T patent/DE3373272D1/de not_active Expired
- 1983-05-18 IE IE1172/83A patent/IE55115B1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
ATE29215T1 (de)	1987-09-15
IL68703A0 (en)	1983-09-30
DE3373272D1 (en)	1987-10-08
PH19295A (en)	1986-03-05
EP0095123B1 (de)	1987-09-02
EP0095123A2 (de)	1983-11-30
AU550992B2 (en)	1986-04-10
NZ204263A (en)	1986-02-21
JPS58210008A (ja)	1983-12-07
IE831172L (en)	1983-11-20
US4421736A (en)	1983-12-20
ZA833489B (en)	1984-02-29
EP0095123A3 (en)	1984-12-12
AU1461783A (en)	1983-11-24
IE55115B1 (en)	1990-06-06

Legal Events

Date	Code	Title	Description
1997-08-14	KB	Patent renewed
2001-07-24	KB20	Patent renewed for 20 years
2003-07-31	EXP	Patent expired
2006-09-05	HC	Change of name of proprietor(s)	Owner name: AVENTIS INC. Free format text: FORMER NAME:MERRELL PHARMACEUTICALS INC.

Publication	Publication Date	Title
AU550992B2 (en)	1986-04-10	Sustained release diethylpropion comppositions
GB2117239B (en)	1987-03-11	Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
ES519423A0 (es)	1985-04-16	Procedimiento para preparar 9-(1 o 3-monoaciloxi-o 1,3-diaciloxi-2-propoximetil)-purinas substituidas en calidad de agentes antiviricos.
IL58279A0 (en)	1979-12-30	Sustained release pharmaceutical compositions
GB2053682B (en)	1983-10-12	Sustained release pharmaceutical compositions
IL67497A (en)	1986-02-28	Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
IT8320775A0 (it)	1983-04-22	Composizioni poliuretaniche a base acquosa e procedimento per la loro preparazione.
WO1991018866A3 (en)	1992-04-30	1,4-diamino-2,3-dihydroxybutanes
TR199800077T1 (xx)	1998-05-21	Kontroll� ��z�len paroksetin terkipleri.
IT8322616A0 (it)	1983-08-23	Composizione per agenti antitumorali.
DE3887839D1 (de)	1994-03-24	Trennmittelzusammensetzung.
EP0114878A4 (de)	1986-03-18	Phthalazin substituierte aminomethylbenzolabkömmlinge, zusammensetzungen und verwendung.
ZA922297B (en)	1992-12-30	Crystalline tiababine monohydrate,its preparation and use
MY100900A (en)	1991-05-16	Substituted phenylsulfonyloxybenzimidazolecarbamates, processes for their preparation and their use as medicaments.
JPS53105477A (en)	1978-09-13	7-glycylprolylamono-4-methylcoumarine
AU8111282A (en)	1982-09-16	1,2,3,6 tetrahydropyridines as anorectic agents
ES8501750A1 (es)	1984-12-01	Un procedimiento para la preparacion de 4-aril-4-piperidincarbinoles.
JPS5332124A (en)	1978-03-27	Carcinostatic agent
DE3278126D1 (en)	1988-03-31	Sustained release compositions
ZA836298B (en)	1984-09-26	Anthelmintic compositions
ZA804421B (en)	1981-09-30	Substituted-1,2,3-thiadiazole-safening agents
AU1734183A (en)	1984-02-02	3alpha-(substituted-phenyl)-3alpah,4,7,7alpha-tetrahydro-4, 7-methanoisoindolines
JPS5250481A (en)	1977-04-22	Air cylinder
ES532109A0 (es)	1985-06-16	Procedimiento para preparar 9-(1 o 3-monoaciloxi-o 1,3-diaciloxi-2-propoximetil)-purinas substituidas en calidad de agentes antiviricos.
IT8220526A0 (it)	1982-04-01	Composizioni acaricide.