IL69722A - Oxopyrimidine derivatives and pharmaceutical compositions containing them - Google Patents

Oxopyrimidine derivatives and pharmaceutical compositions containing them

Info

Publication number
IL69722A
IL69722A IL69722A IL6972283A IL69722A IL 69722 A IL69722 A IL 69722A IL 69722 A IL69722 A IL 69722A IL 6972283 A IL6972283 A IL 6972283A IL 69722 A IL69722 A IL 69722A
Authority
IL
Israel
Prior art keywords
sub
pharmaceutical compositions
compositions containing
hydrogen
compounds
Prior art date
Application number
IL69722A
Other languages
English (en)
Other versions
IL69722A0 (en
Original Assignee
Taro Pharma Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taro Pharma Ind filed Critical Taro Pharma Ind
Priority to IL69722A priority Critical patent/IL69722A/xx
Publication of IL69722A0 publication Critical patent/IL69722A0/xx
Priority to US06/647,680 priority patent/US4628056A/en
Priority to AU32875/84A priority patent/AU571265B2/en
Priority to DK431784A priority patent/DK167615B1/da
Priority to DE8484110959T priority patent/DE3485318D1/de
Priority to EP84110959A priority patent/EP0137343B1/de
Priority to AT84110959T priority patent/ATE70056T1/de
Priority to JP19241384A priority patent/JPH0730044B2/ja
Priority to IE233284A priority patent/IE58038B1/en
Priority to ZA847274A priority patent/ZA847274B/xx
Publication of IL69722A publication Critical patent/IL69722A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60—Three or more oxygen or sulfur atoms
    • C07D239/62—Barbituric acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
IL69722A 1983-09-14 1983-09-14 Oxopyrimidine derivatives and pharmaceutical compositions containing them IL69722A (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
IL69722A IL69722A (en) 1983-09-14 1983-09-14 Oxopyrimidine derivatives and pharmaceutical compositions containing them
US06/647,680 US4628056A (en) 1983-09-14 1984-09-05 Novel oxopyrimidine derivatives, pharmaceutical compositions containing them and their use as anticonvulsant, antianxiety and muscle relaxant agents
AU32875/84A AU571265B2 (en) 1983-09-14 1984-09-10 Oxopyrimidine derivatives
DK431784A DK167615B1 (da) 1983-09-14 1984-09-11 Barbitursyrederivater og farmaceutiske praeparater indeholdende saadanne
IE233284A IE58038B1 (en) 1983-09-14 1984-09-13 Novel oxopyrimidine derivatives and pharmaceutical compositions containing them
DE8484110959T DE3485318D1 (de) 1983-09-14 1984-09-13 Oxopyrimidin-derivate und sie enthaltende pharmazeutische zubereitungen.
EP84110959A EP0137343B1 (de) 1983-09-14 1984-09-13 Oxopyrimidin-Derivate und sie enthaltende pharmazeutische Zubereitungen
AT84110959T ATE70056T1 (de) 1983-09-14 1984-09-13 Oxopyrimidin-derivate und sie enthaltende pharmazeutische zubereitungen.
JP19241384A JPH0730044B2 (ja) 1983-09-14 1984-09-13 新規なるオキソピリミジン誘導体
ZA847274A ZA847274B (en) 1983-09-14 1984-09-14 Oxopyramidine derivatives and pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL69722A IL69722A (en) 1983-09-14 1983-09-14 Oxopyrimidine derivatives and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
IL69722A0 IL69722A0 (en) 1983-12-30
IL69722A true IL69722A (en) 1986-09-30

Family

ID=11054532

Family Applications (1)

Application Number Title Priority Date Filing Date
IL69722A IL69722A (en) 1983-09-14 1983-09-14 Oxopyrimidine derivatives and pharmaceutical compositions containing them

Country Status (10)

Country Link
US (1) US4628056A (de)
EP (1) EP0137343B1 (de)
JP (1) JPH0730044B2 (de)
AT (1) ATE70056T1 (de)
AU (1) AU571265B2 (de)
DE (1) DE3485318D1 (de)
DK (1) DK167615B1 (de)
IE (1) IE58038B1 (de)
IL (1) IL69722A (de)
ZA (1) ZA847274B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0223037A1 (de) * 1985-10-24 1987-05-27 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Phenylbarbitursäuren und deren Herstellung
US6093820A (en) * 1997-10-02 2000-07-25 Taro Pharmaceutical Industries Ltd. Method and reagents for N-alkylating ureides
CA2306170A1 (en) * 2000-04-18 2001-10-18 Kenneth Curry Novel amino, carboxy derivatives of barbituric acid
US6939873B2 (en) * 2000-07-26 2005-09-06 Taro Pharmaceuticals Industries Limited Non-sedating barbituric acid derivatives
US7683071B2 (en) * 2000-07-26 2010-03-23 Taro Pharmaceuticals Industries Ltd. Composition and method for improved bioavailability and enhanced brain delivery of 5,5-diphenyl barbituric acid
AU2007200460B2 (en) * 2000-07-26 2009-10-08 Taro Pharmaceutical Industries Ltd. Non-sedating barbiturate compounds as neuroprotective agents
EP1905441A3 (de) * 2000-07-26 2008-04-23 Taro Pharmaceutical Industries Limited Nicht-sedierende Barbituratverbindungen als neuroprotektive Wirkstoffe
DE60132337T2 (de) * 2000-07-26 2009-02-12 Taro Pharmaceutical Industries Ltd. Nicht-sedierende barbituratverbindungen als neuroprotektive wirkstoffe
US6756379B2 (en) 2001-07-26 2004-06-29 Taro Pharmaceutical Industries Ltd. Non-sedating barbiturate compounds as neuroprotective agents
RU2196579C2 (ru) * 2001-02-08 2003-01-20 Амурская государственная медицинская академия Способ снижения уровня тревожности у лабораторных животных в эксперименте
JP2005516052A (ja) * 2002-01-30 2005-06-02 タロ ファーマシューティカル インダストリーズ リミテッド 非鎮静性バルビツール酸誘導体
US6810318B2 (en) * 2002-09-13 2004-10-26 General Motors Corporation Drive torque transfer scheme
CL2003002588A1 (es) * 2002-12-11 2005-01-07 Taro Pharmaceuticals Ireland L Uso de una composicion farmaceutica que comprende acido n,n-dimetoximetildifenil barbiturico, acido n-metoximetildifenil barbiturico o acido difenil barbiturico o una sal farmaceuticamente aceptable del mismo para preparar un medicamento util en el t
EP1781624A4 (de) * 2004-07-02 2010-06-23 Taro Pharma Ind Verfahren zur herstellung von 1-methoxymethyl-5,5-diphenylbarbitursäure
EP1625848A1 (de) * 2004-08-10 2006-02-15 Taro Pharmaceuticals North America, Inc. Zusammensetzung und Verfahren zur verbesserten Abgabe von 5,5-Diphenylbarbitursäure
WO2008066704A2 (en) * 2006-11-14 2008-06-05 Taro Pharmaceuticals North America, Inc. Method of improving bioavailability for non-sedating barbiturates
WO2013038427A1 (en) * 2011-09-12 2013-03-21 Council Of Scientific & Industrial Research ARYLATED β-DICARBOIMYL COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1960170A (en) * 1934-05-22 Cc - phenylethyl - n -
US3930006A (en) * 1963-04-30 1975-12-30 Aspro Nicholas Ltd Antiparkinsonism compositions and method
US4046894A (en) * 1968-08-05 1977-09-06 Bristol-Myers Company Certain barbituric acid derivatives used as anticonvulsant agents
US3919427A (en) * 1972-06-02 1975-11-11 Kendall & Co Therapeutic compositions containing 1-methyl-3-alkoxymethyl-5,5-disubstituted barbituric acid compounds
US3948896A (en) * 1973-02-28 1976-04-06 The Kendall Company N-mono(alkoxymethyl) phenobarbitals, process therefor and therapeutic composition and method containing same

Also Published As

Publication number Publication date
ZA847274B (en) 1986-04-30
IE58038B1 (en) 1993-06-16
DE3485318D1 (de) 1992-01-16
JPH0730044B2 (ja) 1995-04-05
EP0137343A3 (en) 1986-06-11
DK431784D0 (da) 1984-09-11
DK167615B1 (da) 1993-11-29
AU3287584A (en) 1985-03-21
EP0137343B1 (de) 1991-12-04
IL69722A0 (en) 1983-12-30
IE842332L (en) 1985-03-14
US4628056A (en) 1986-12-09
ATE70056T1 (de) 1991-12-15
EP0137343A2 (de) 1985-04-17
JPS6084272A (ja) 1985-05-13
DK431784A (da) 1985-03-15
AU571265B2 (en) 1988-04-14

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Legal Events

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