ZA847274B - Oxopyramidine derivatives and pharmaceutical compositions containing them - Google Patents

Oxopyramidine derivatives and pharmaceutical compositions containing them

Info

Publication number: ZA847274B
Authority: ZA; South Africa
Prior art keywords: sub; pharmaceutical compositions; compositions containing; derivatives; oxopyramidine
Prior art date: 1983-09-14

Application number

ZA847274A

Other languages

English (en)

Inventor

Barrie Levitt

Morris Stolar

Original Assignee

Taro Pharma Ind

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-09-14

Filing date

1984-09-14

Publication date

1986-04-30

1984-09-14 Application filed by Taro Pharma Ind filed Critical Taro Pharma Ind

1986-04-30 Publication of ZA847274B publication Critical patent/ZA847274B/xx

Links

239000008194 pharmaceutical composition Substances 0.000 title abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
230000000049 anti-anxiety effect Effects 0.000 abstract 1
230000001773 anti-convulsant effect Effects 0.000 abstract 1
239000001961 anticonvulsive agent Substances 0.000 abstract 1
229960003965 antiepileptics Drugs 0.000 abstract 1
239000002249 anxiolytic agent Substances 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
150000002431 hydrogen Chemical class 0.000 abstract 1
239000003158 myorelaxant agent Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/60—Three or more oxygen or sulfur atoms
- C07D239/62—Barbituric acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Pain & Pain Management (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Anesthesiology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

ZA847274A 1983-09-14 1984-09-14 Oxopyramidine derivatives and pharmaceutical compositions containing them ZA847274B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IL69722A IL69722A (en)	1983-09-14	1983-09-14	Oxopyrimidine derivatives and pharmaceutical compositions containing them

Publications (1)

Publication Number	Publication Date
ZA847274B true ZA847274B (en)	1986-04-30

Family

ID=11054532

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA847274A ZA847274B (en)	1983-09-14	1984-09-14	Oxopyramidine derivatives and pharmaceutical compositions containing them

Country Status (10)

Country	Link
US (1)	US4628056A (de)
EP (1)	EP0137343B1 (de)
JP (1)	JPH0730044B2 (de)
AT (1)	ATE70056T1 (de)
AU (1)	AU571265B2 (de)
DE (1)	DE3485318D1 (de)
DK (1)	DK167615B1 (de)
IE (1)	IE58038B1 (de)
IL (1)	IL69722A (de)
ZA (1)	ZA847274B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0223037A1 (de) *	1985-10-24	1987-05-27	F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft	Phenylbarbitursäuren und deren Herstellung
US6093820A (en)	1997-10-02	2000-07-25	Taro Pharmaceutical Industries Ltd.	Method and reagents for N-alkylating ureides
CA2306170A1 (en) *	2000-04-18	2001-10-18	Kenneth Curry	Novel amino, carboxy derivatives of barbituric acid
AU2007200460B2 (en) *	2000-07-26	2009-10-08	Taro Pharmaceutical Industries Ltd.	Non-sedating barbiturate compounds as neuroprotective agents
US7683071B2 (en) *	2000-07-26	2010-03-23	Taro Pharmaceuticals Industries Ltd.	Composition and method for improved bioavailability and enhanced brain delivery of 5,5-diphenyl barbituric acid
US6939873B2 (en) *	2000-07-26	2005-09-06	Taro Pharmaceuticals Industries Limited	Non-sedating barbituric acid derivatives
EP1905441A3 (de) *	2000-07-26	2008-04-23	Taro Pharmaceutical Industries Limited	Nicht-sedierende Barbituratverbindungen als neuroprotektive Wirkstoffe
US6756379B2 (en)	2001-07-26	2004-06-29	Taro Pharmaceutical Industries Ltd.	Non-sedating barbiturate compounds as neuroprotective agents
WO2002007729A1 (en) *	2000-07-26	2002-01-31	Taro Pharmaceutical Industries Ltd.	Non-sedating barbiturate compounds as neuroprotective agents
RU2196579C2 (ru) *	2001-02-08	2003-01-20	Амурская государственная медицинская академия	Способ снижения уровня тревожности у лабораторных животных в эксперименте
EP1485101A4 (de) *	2002-01-30	2006-04-12	Taro Pharma Ind	Nichtsedierende barbitursäure-derivate
US6810318B2 (en) *	2002-09-13	2004-10-26	General Motors Corporation	Drive torque transfer scheme
WO2004052350A2 (en) *	2002-12-11	2004-06-24	Taro Pharmaceutical Industries Limited	Method of treating movement disorders using barbituric acid derivatives
WO2006003651A2 (en) *	2004-07-02	2006-01-12	Taro Pharmaceutical Industries, Ltd	A process for preparing 1-methoxymethyl-5,5-diphenylbarbituric acid
EP1625848A1 (de) *	2004-08-10	2006-02-15	Taro Pharmaceuticals North America, Inc.	Zusammensetzung und Verfahren zur verbesserten Abgabe von 5,5-Diphenylbarbitursäure
EP2081576A4 (de) *	2006-11-14	2010-06-30	Taro Pharmaceuticals North Ame	Verfahren zur verbesserung der bioverfügbarkeit für nichtsedierende barbiturate
WO2013038427A1 (en) *	2011-09-12	2013-03-21	Council Of Scientific & Industrial Research	ARYLATED β-DICARBOIMYL COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US1960170A (en) *		1934-05-22		Cc - phenylethyl - n -
US3930006A (en) *	1963-04-30	1975-12-30	Aspro Nicholas Ltd	Antiparkinsonism compositions and method
US4046894A (en) *	1968-08-05	1977-09-06	Bristol-Myers Company	Certain barbituric acid derivatives used as anticonvulsant agents
US3919427A (en) *	1972-06-02	1975-11-11	Kendall & Co	Therapeutic compositions containing 1-methyl-3-alkoxymethyl-5,5-disubstituted barbituric acid compounds
US3948896A (en) *	1973-02-28	1976-04-06	The Kendall Company	N-mono(alkoxymethyl) phenobarbitals, process therefor and therapeutic composition and method containing same

1983
- 1983-09-14 IL IL69722A patent/IL69722A/xx not_active IP Right Cessation
1984
- 1984-09-05 US US06/647,680 patent/US4628056A/en not_active Expired - Lifetime
- 1984-09-10 AU AU32875/84A patent/AU571265B2/en not_active Ceased
- 1984-09-11 DK DK431784A patent/DK167615B1/da not_active IP Right Cessation
- 1984-09-13 DE DE8484110959T patent/DE3485318D1/de not_active Expired - Lifetime
- 1984-09-13 JP JP19241384A patent/JPH0730044B2/ja not_active Expired - Lifetime
- 1984-09-13 IE IE233284A patent/IE58038B1/en not_active IP Right Cessation
- 1984-09-13 AT AT84110959T patent/ATE70056T1/de not_active IP Right Cessation
- 1984-09-13 EP EP84110959A patent/EP0137343B1/de not_active Expired - Lifetime
- 1984-09-14 ZA ZA847274A patent/ZA847274B/xx unknown

Also Published As

Publication number	Publication date
EP0137343A2 (de)	1985-04-17
IE842332L (en)	1985-03-14
IE58038B1 (en)	1993-06-16
JPS6084272A (ja)	1985-05-13
DK167615B1 (da)	1993-11-29
DK431784D0 (da)	1984-09-11
US4628056A (en)	1986-12-09
IL69722A0 (en)	1983-12-30
ATE70056T1 (de)	1991-12-15
EP0137343B1 (de)	1991-12-04
AU571265B2 (en)	1988-04-14
EP0137343A3 (en)	1986-06-11
JPH0730044B2 (ja)	1995-04-05
AU3287584A (en)	1985-03-21
IL69722A (en)	1986-09-30
DK431784A (da)	1985-03-15
DE3485318D1 (de)	1992-01-16

Publication	Publication Date	Title
EP0137343A3 (en)	1986-06-11	Novel oxopyrimidine derivatives and pharmaceutical compositions containing them
AU543054B2 (en)	1985-03-28	Heterocyclic amine derivatives
TR200001603T2 (tr)	2000-10-23	Yeni bileşikler
EP0572857A3 (en)	1994-05-25	Improved additive composition for oil well cementing formulations
ES8505927A1 (es)	1985-06-16	Procedimiento para la preparacion de derivados de 1-(fenil)-1-hidroxi-2-amino-3-fluoro-propano
MY112148A (en)	2001-04-30	Suspension concentrate compositions of arylpyrrole insecticidal and acarricidal agents
ES8707525A1 (es)	1987-08-01	Un procedimiento para la preparacion de nuevas isoindolinil-alquilpiperazinas
MX9702203A (es)	1997-06-28	Derivados de pirazolil-pirazol substituidos, procedimientos para su preparacion y su uso como agentes con accion herbicida.
IL111966A0 (en)	1995-03-15	4-Benzoylisoxazole derivatives, their preparation and herbicidal compositions containing them
ZA895623B (en)	1990-05-30	Tetracyclic antidepressants
CA1230115A (en)	1987-12-08	ANTHRA[1,9-CD]PYRAZOL-6(2H)-ONES SUBSTITUTES
IL123080A0 (en)	1998-09-24	Carbamoylcarboxamides their preparation and use
ES8501607A1 (es)	1984-12-01	Procedimiento para la obtencion de heterociclos nitrogenosos de 5 miembros
NZ333854A (en)	2000-12-22	Intermediates for the preparation of 2-imidazoline-5-ones
ES8407481A1 (es)	1984-10-01	"procedimiento para la preparacion de alfa-(1-triazolil)-ceto-derivados"
ES8601182A1 (es)	1985-11-01	Procedimiento para la obtencion de tiolan-2,4-dion-3-carboxamidas
GR74782B (de)	1984-07-12
IT8421331A0 (it)	1984-06-08	Composizioni e procedimento per la stabilizzazione di antralina.
WO1999065318A3 (de)	2003-04-17	Germinal substituierte amine
IL111246A0 (en)	1994-12-29	Tricyclic compounds and pharmaceutical compositions containing them
ATE204847T1 (de)	2001-09-15	Tetracyclische aromatische retinoide verbindungen,ihre herstellung und verwendung
ES2059261A1 (es)	1994-11-01	Alquil-bisacilfosfinoxidos.
DE3676898D1 (en)	1991-02-21	Ungesaettigte thiocarbonsaeureamide als pestizide.
MD424G2 (ro)	1996-07-31	Derivaţi ai amidei
AP9300577A0 (en)	1995-04-04	Cyanophenyl-pyrazolines.