IL72763A - Polyol esters,their preparation and their use as depot matrix material for pharmacologically active substances - Google Patents
Polyol esters,their preparation and their use as depot matrix material for pharmacologically active substancesInfo
- Publication number
- IL72763A IL72763A IL72763A IL7276384A IL72763A IL 72763 A IL72763 A IL 72763A IL 72763 A IL72763 A IL 72763A IL 7276384 A IL7276384 A IL 7276384A IL 72763 A IL72763 A IL 72763A
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- matrix material
- active substances
- pharmacologically active
- polyol esters
- Prior art date
Links
- -1 Polyol esters Chemical class 0.000 title 1
- 239000013543 active substance Substances 0.000 title 1
- 239000011159 matrix material Substances 0.000 title 1
- 229920005862 polyol Polymers 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/66—Polyesters containing oxygen in the form of ether groups
- C08G63/664—Polyesters containing oxygen in the form of ether groups derived from hydroxy carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
- A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
- C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
- C08G63/08—Lactones or lactides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/915—Therapeutic or pharmaceutical composition
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Polymers & Plastics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Polyesters Or Polycarbonates (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH4671/83A CH656884A5 (de) | 1983-08-26 | 1983-08-26 | Polyolester, deren herstellung und verwendung. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL72763A0 IL72763A0 (en) | 1984-11-30 |
| IL72763A true IL72763A (en) | 1988-02-29 |
Family
ID=4280440
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL72763A IL72763A (en) | 1983-08-26 | 1984-08-24 | Polyol esters,their preparation and their use as depot matrix material for pharmacologically active substances |
Country Status (27)
| Country | Link |
|---|---|
| US (2) | US5922682A (fr) |
| JP (1) | JPH0819226B2 (fr) |
| AT (1) | AT395584B (fr) |
| AU (1) | AU575066B2 (fr) |
| BE (1) | BE900406A (fr) |
| CH (1) | CH656884A5 (fr) |
| CY (1) | CY1556A (fr) |
| DE (1) | DE3430852C2 (fr) |
| DK (1) | DK173556B1 (fr) |
| ES (1) | ES8706750A1 (fr) |
| FR (1) | FR2551072B1 (fr) |
| GB (1) | GB2145422B (fr) |
| GR (1) | GR80184B (fr) |
| HK (1) | HK67390A (fr) |
| HU (1) | HU195426B (fr) |
| IE (1) | IE58818B1 (fr) |
| IL (1) | IL72763A (fr) |
| IT (1) | IT1176629B (fr) |
| LU (1) | LU85514A1 (fr) |
| MY (1) | MY101861A (fr) |
| NL (2) | NL190415C (fr) |
| NZ (1) | NZ209335A (fr) |
| PH (1) | PH23556A (fr) |
| PT (1) | PT79129B (fr) |
| SE (1) | SE462098B (fr) |
| SG (1) | SG53590G (fr) |
| ZA (1) | ZA846634B (fr) |
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| CA2025893A1 (fr) * | 1989-01-27 | 1990-07-28 | Hosei Shinoda | Polyester biocompatible et sa production |
| PH30995A (en) * | 1989-07-07 | 1997-12-23 | Novartis Inc | Sustained release formulations of water soluble peptides. |
| US5538739A (en) * | 1989-07-07 | 1996-07-23 | Sandoz Ltd. | Sustained release formulations of water soluble peptides |
| HU221294B1 (en) * | 1989-07-07 | 2002-09-28 | Novartis Ag | Process for producing retarde compositions containing the active ingredient in a polymeric carrier |
| MY108621A (en) * | 1990-08-01 | 1996-10-31 | Novartis Ag | Polylactide preparation and purification |
| US6353030B1 (en) * | 1990-08-01 | 2002-03-05 | Novartis Ag | Relating to organic compounds |
| CA2066616A1 (fr) * | 1990-10-01 | 1992-04-02 | Masanobu Yoshinaga | Polymere de cyclodextrine et membrane de cyclodextrine preparee a l'aide de ce polymere |
| US5225521A (en) * | 1991-12-31 | 1993-07-06 | E. I. Du Pont De Nemours And Company | Star-shaped hydroxyacid polymers |
| US6326458B1 (en) | 1992-01-24 | 2001-12-04 | Cargill, Inc. | Continuous process for the manufacture of lactide and lactide polymers |
| US5247058A (en) * | 1992-01-24 | 1993-09-21 | Cargill, Incorporated | Continuous process for manufacture of lactide polymers with controlled optical purity |
| US5258488A (en) * | 1992-01-24 | 1993-11-02 | Cargill, Incorporated | Continuous process for manufacture of lactide polymers with controlled optical purity |
| US6005067A (en) * | 1992-01-24 | 1999-12-21 | Cargill Incorporated | Continuous process for manufacture of lactide polymers with controlled optical purity |
| US5142023A (en) * | 1992-01-24 | 1992-08-25 | Cargill, Incorporated | Continuous process for manufacture of lactide polymers with controlled optical purity |
| US5247059A (en) * | 1992-01-24 | 1993-09-21 | Cargill, Incorporated | Continuous process for the manufacture of a purified lactide from esters of lactic acid |
| GB9206736D0 (en) * | 1992-03-27 | 1992-05-13 | Sandoz Ltd | Improvements of organic compounds and their use in pharmaceutical compositions |
| FR2692167B1 (fr) * | 1992-06-16 | 1994-09-16 | Centre Nat Rech Scient | Préparation et application de nouveaux systèmes colloïdaux nanovésiculaires dispersibles à base de cyclodextrine, sous forme de nanocapsules. |
| FR2692168B1 (fr) * | 1992-06-16 | 1995-03-24 | Centre Nat Rech Scient | Préparation et utilisation de nouveaux systèmes colloïdaux dispersibles à base de cyclodextrine, sous forme de nanosphères. |
| AU4198793A (en) † | 1992-07-24 | 1994-01-27 | Takeda Chemical Industries Ltd. | Microparticle preparation and production thereof |
| BR9305661A (pt) * | 1992-10-02 | 1996-11-26 | Cargill Inc | Pano de polímero de lactideo estável em fusao e processo para a sua fabricaçao |
| US5338822A (en) * | 1992-10-02 | 1994-08-16 | Cargill, Incorporated | Melt-stable lactide polymer composition and process for manufacture thereof |
| US6005068A (en) * | 1992-10-02 | 1999-12-21 | Cargill Incorporated | Melt-stable amorphous lactide polymer film and process for manufacture thereof |
| NZ256978A (en) * | 1992-10-02 | 1996-05-28 | Cargill Inc | Paper product coated with a poly(lactide) composition comprising no more than 5 wt % lactide monomer, the poly(lactide) having a number average mw of 10,000 to 200,000 |
| TW333456B (en) | 1992-12-07 | 1998-06-11 | Takeda Pharm Ind Co Ltd | A pharmaceutical composition of sustained-release preparation the invention relates to a pharmaceutical composition of sustained-release preparation which comprises a physiologically active peptide. |
| US5594091A (en) * | 1994-02-21 | 1997-01-14 | Takeda Chemical Industries, Ltd. | Matrix for sustained-release preparation |
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| US5817728A (en) * | 1995-03-16 | 1998-10-06 | Mitsui Chemicals, Inc. | Preparation of degradable copolymers |
| US5914381A (en) * | 1996-09-12 | 1999-06-22 | Mitsui Chemicals, Inc. | Degradable polymer and preparation process of the same |
| US5916883A (en) * | 1996-11-01 | 1999-06-29 | Poly-Med, Inc. | Acylated cyclodextrin derivatives |
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| JP2002528602A (ja) | 1998-11-02 | 2002-09-03 | ソシエテ・ドゥ・コンセイユ・ドゥ・ルシェルシュ・エ・ダプリカーション・シャンティフィック・エス・ア・エス | ラクトンを保有する吸収性ポリマー |
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| US8614291B2 (en) | 1999-08-10 | 2013-12-24 | Poly-Med, Inc. | Phosphorylated polymers and conjugates thereof |
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| DE10111767B4 (de) * | 2001-03-12 | 2005-03-24 | Schwarz Pharma Ag | Verfahren zur Herstellung von Polyestern aus Hydroxycarbonsäuren und Polyolen durch Polykondensation |
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| ES2436439T3 (es) | 2001-10-30 | 2014-01-02 | Novartis Ag | Formulaciones de medicamento de liberación lenta de iloperidona con un polímero |
| EP2316468A1 (fr) | 2002-02-22 | 2011-05-04 | Shire LLC | Système de distribution et méthodes de protection et d'administration de dextroamphetamine |
| GB0216416D0 (en) | 2002-07-15 | 2002-08-21 | Novartis Ag | Organic compounds |
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| US20060089384A1 (en) * | 2004-10-25 | 2006-04-27 | Minno George E | Ophthalmic compositions and methods of using the same |
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| WO2008029527A1 (fr) * | 2006-09-04 | 2008-03-13 | Bio-Energy Corporation | Polyol de polyester |
| CN100460441C (zh) * | 2006-09-25 | 2009-02-11 | 南开大学 | 生物可降解星型结构聚乙丙交酯载药微球及其制备方法 |
| NO347209B1 (no) | 2006-12-18 | 2023-07-03 | Takeda Pharmaceutical | Sammensetning med forlenget frigjøring og fremgangsmåte for å produsere det samme |
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| RU2490009C2 (ru) | 2008-02-22 | 2013-08-20 | Торэй Индастриз, Инк. | Микрочастица и ее фармацевтическая композиция |
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| EP2172189A1 (fr) | 2008-10-01 | 2010-04-07 | Novartis AG | Compositions pharmaceutiques |
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| IE35855B1 (en) * | 1970-12-18 | 1976-06-09 | Ethicon Inc | Absorbable copolymer suture |
| US3963699A (en) * | 1974-01-10 | 1976-06-15 | The Procter & Gamble Company | Synthesis of higher polyol fatty acid polyesters |
| NO142306C (no) * | 1975-04-18 | 1980-07-30 | Tate & Lyle Ltd | Fremgangsmaate til rensing av et fast stoff i form av et omestringsprodukt frembrakt ved reaksjon mellom sukrose og minst ett fettsyretriglycerid |
| US4328204A (en) * | 1977-03-02 | 1982-05-04 | Ethicon, Inc. | Absorbable polymer-drug compounds and method for making same |
| DE2856901D2 (de) * | 1977-06-07 | 1980-11-13 | Garching Instrumente | Form of implant medicament and preparation process |
| US4130639A (en) * | 1977-09-28 | 1978-12-19 | Ethicon, Inc. | Absorbable pharmaceutical compositions based on isomorphic copolyoxalates |
| US4165432A (en) * | 1977-10-18 | 1979-08-21 | Olin Corporation | Peroxy di-ester polyols |
| DE2824112A1 (de) * | 1978-06-01 | 1979-12-06 | Garching Instrumente | Mikropellets, verfahren zu ihrer herstellung und deren verwendung |
| US4273920A (en) * | 1979-09-12 | 1981-06-16 | Eli Lilly And Company | Polymerization process and product |
| US4334061A (en) * | 1979-10-29 | 1982-06-08 | Ethyl Corporation | Process for recovery of polyol fatty acid polyesters |
| DE3045135A1 (de) * | 1980-11-29 | 1982-06-09 | Sandoz-Patent-GmbH, 7850 Lörrach | Pharmazeutische kompositionen enthaltende bioabbaubare polymere |
| IE52535B1 (en) * | 1981-02-16 | 1987-12-09 | Ici Plc | Continuous release pharmaceutical compositions |
| ATE37983T1 (de) * | 1982-04-22 | 1988-11-15 | Ici Plc | Mittel mit verzoegerter freigabe. |
| US4452973A (en) * | 1982-11-12 | 1984-06-05 | American Cyanamid Company | Poly(glycolic acid)/poly(oxyethylene) triblock copolymers and method of manufacturing the same |
| FR2537980B1 (fr) * | 1982-12-17 | 1986-12-19 | Sandoz Sa | Derives d'acides hydroxycarboxyliques oligomeres, leur preparation et leur utilisation |
-
1983
- 1983-08-26 CH CH4671/83A patent/CH656884A5/de not_active IP Right Cessation
-
1984
- 1984-08-20 NL NLAANVRAGE8402547,A patent/NL190415C/xx not_active IP Right Cessation
- 1984-08-21 FR FR8413111A patent/FR2551072B1/fr not_active Expired
- 1984-08-21 HU HU843146A patent/HU195426B/hu unknown
- 1984-08-22 BE BE1/11073A patent/BE900406A/fr not_active IP Right Cessation
- 1984-08-22 DE DE3430852A patent/DE3430852C2/de not_active Expired - Lifetime
- 1984-08-22 GB GB08421273A patent/GB2145422B/en not_active Expired
- 1984-08-23 GR GR80184A patent/GR80184B/el unknown
- 1984-08-24 AT AT0271384A patent/AT395584B/de active
- 1984-08-24 IE IE217184A patent/IE58818B1/xx not_active IP Right Cessation
- 1984-08-24 IL IL72763A patent/IL72763A/xx not_active IP Right Cessation
- 1984-08-24 PH PH31143A patent/PH23556A/en unknown
- 1984-08-24 PT PT79129A patent/PT79129B/pt unknown
- 1984-08-24 NZ NZ209335A patent/NZ209335A/xx unknown
- 1984-08-24 ES ES535399A patent/ES8706750A1/es not_active Expired
- 1984-08-24 SE SE8404225A patent/SE462098B/sv not_active IP Right Cessation
- 1984-08-24 ZA ZA846634A patent/ZA846634B/xx unknown
- 1984-08-24 JP JP59177375A patent/JPH0819226B2/ja not_active Expired - Lifetime
- 1984-08-24 AU AU32348/84A patent/AU575066B2/en not_active Expired
- 1984-08-24 LU LU85514A patent/LU85514A1/fr unknown
- 1984-08-24 IT IT22413/84A patent/IT1176629B/it active Protection Beyond IP Right Term
- 1984-08-24 DK DK198404072A patent/DK173556B1/da not_active IP Right Cessation
-
1987
- 1987-09-24 MY MYPI87001920A patent/MY101861A/en unknown
-
1990
- 1990-07-11 SG SG535/90A patent/SG53590G/en unknown
- 1990-08-30 HK HK673/90A patent/HK67390A/xx not_active IP Right Cessation
-
1991
- 1991-03-22 CY CY1556A patent/CY1556A/en unknown
-
1992
- 1992-02-11 US US07/834,018 patent/US5922682A/en not_active Expired - Lifetime
-
1995
- 1995-06-06 US US08/471,304 patent/US5922338A/en not_active Expired - Lifetime
-
1996
- 1996-06-06 NL NL960014C patent/NL960014I1/nl unknown
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Legal Events
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| HC | Change of name of proprietor(s) | ||
| KB | Patent renewed | ||
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| EXP | Patent expired |