SG53590G - Novel polyesters,their preparation and pharmaceutical use - Google Patents

Novel polyesters,their preparation and pharmaceutical use

Info

Publication number
SG53590G
SG53590G SG535/90A SG53590A SG53590G SG 53590 G SG53590 G SG 53590G SG 535/90 A SG535/90 A SG 535/90A SG 53590 A SG53590 A SG 53590A SG 53590 G SG53590 G SG 53590G
Authority
SG
Singapore
Prior art keywords
preparation
pharmaceutical use
novel polyesters
polyesters
novel
Prior art date
Application number
SG535/90A
Other languages
English (en)
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of SG53590G publication Critical patent/SG53590G/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/66—Polyesters containing oxygen in the form of ether groups
    • C08G63/664—Polyesters containing oxygen in the form of ether groups derived from hydroxy carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
    • C08G63/08—Lactones or lactides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/915—Therapeutic or pharmaceutical composition

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Polymers & Plastics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG535/90A 1983-08-26 1990-07-11 Novel polyesters,their preparation and pharmaceutical use SG53590G (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH4671/83A CH656884A5 (de) 1983-08-26 1983-08-26 Polyolester, deren herstellung und verwendung.

Publications (1)

Publication Number Publication Date
SG53590G true SG53590G (en) 1990-10-26

Family

ID=4280440

Family Applications (1)

Application Number Title Priority Date Filing Date
SG535/90A SG53590G (en) 1983-08-26 1990-07-11 Novel polyesters,their preparation and pharmaceutical use

Country Status (27)

Country Link
US (2) US5922682A (fr)
JP (1) JPH0819226B2 (fr)
AT (1) AT395584B (fr)
AU (1) AU575066B2 (fr)
BE (1) BE900406A (fr)
CH (1) CH656884A5 (fr)
CY (1) CY1556A (fr)
DE (1) DE3430852C2 (fr)
DK (1) DK173556B1 (fr)
ES (1) ES8706750A1 (fr)
FR (1) FR2551072B1 (fr)
GB (1) GB2145422B (fr)
GR (1) GR80184B (fr)
HK (1) HK67390A (fr)
HU (1) HU195426B (fr)
IE (1) IE58818B1 (fr)
IL (1) IL72763A (fr)
IT (1) IT1176629B (fr)
LU (1) LU85514A1 (fr)
MY (1) MY101861A (fr)
NL (2) NL190415C (fr)
NZ (1) NZ209335A (fr)
PH (1) PH23556A (fr)
PT (1) PT79129B (fr)
SE (1) SE462098B (fr)
SG (1) SG53590G (fr)
ZA (1) ZA846634B (fr)

Families Citing this family (107)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2551756B2 (ja) * 1985-05-07 1996-11-06 武田薬品工業株式会社 ポリオキシカルボン酸エステルおよびその製造法
DE3641692A1 (de) * 1986-12-06 1988-06-09 Boehringer Ingelheim Kg Katalysatorfreie resorbierbare homopolymere und copolymere
GB8801863D0 (en) * 1988-01-28 1988-02-24 Fulmer Yarsley Ltd Pharmaceutical formulations with controlled drug release
US5247013A (en) * 1989-01-27 1993-09-21 Mitsui Toatsu Chemicals, Inc. Biocompatible polyester and production thereof
CA2025893A1 (fr) * 1989-01-27 1990-07-28 Hosei Shinoda Polyester biocompatible et sa production
PH30995A (en) * 1989-07-07 1997-12-23 Novartis Inc Sustained release formulations of water soluble peptides.
US5538739A (en) * 1989-07-07 1996-07-23 Sandoz Ltd. Sustained release formulations of water soluble peptides
HU221294B1 (en) * 1989-07-07 2002-09-28 Novartis Ag Process for producing retarde compositions containing the active ingredient in a polymeric carrier
MY108621A (en) * 1990-08-01 1996-10-31 Novartis Ag Polylactide preparation and purification
US6353030B1 (en) * 1990-08-01 2002-03-05 Novartis Ag Relating to organic compounds
CA2066616A1 (fr) * 1990-10-01 1992-04-02 Masanobu Yoshinaga Polymere de cyclodextrine et membrane de cyclodextrine preparee a l'aide de ce polymere
US5225521A (en) * 1991-12-31 1993-07-06 E. I. Du Pont De Nemours And Company Star-shaped hydroxyacid polymers
US6326458B1 (en) 1992-01-24 2001-12-04 Cargill, Inc. Continuous process for the manufacture of lactide and lactide polymers
US5247058A (en) * 1992-01-24 1993-09-21 Cargill, Incorporated Continuous process for manufacture of lactide polymers with controlled optical purity
US5258488A (en) * 1992-01-24 1993-11-02 Cargill, Incorporated Continuous process for manufacture of lactide polymers with controlled optical purity
US6005067A (en) * 1992-01-24 1999-12-21 Cargill Incorporated Continuous process for manufacture of lactide polymers with controlled optical purity
US5142023A (en) * 1992-01-24 1992-08-25 Cargill, Incorporated Continuous process for manufacture of lactide polymers with controlled optical purity
US5247059A (en) * 1992-01-24 1993-09-21 Cargill, Incorporated Continuous process for the manufacture of a purified lactide from esters of lactic acid
GB9206736D0 (en) * 1992-03-27 1992-05-13 Sandoz Ltd Improvements of organic compounds and their use in pharmaceutical compositions
FR2692167B1 (fr) * 1992-06-16 1994-09-16 Centre Nat Rech Scient Préparation et application de nouveaux systèmes colloïdaux nanovésiculaires dispersibles à base de cyclodextrine, sous forme de nanocapsules.
FR2692168B1 (fr) * 1992-06-16 1995-03-24 Centre Nat Rech Scient Préparation et utilisation de nouveaux systèmes colloïdaux dispersibles à base de cyclodextrine, sous forme de nanosphères.
AU4198793A (en) † 1992-07-24 1994-01-27 Takeda Chemical Industries Ltd. Microparticle preparation and production thereof
BR9305661A (pt) * 1992-10-02 1996-11-26 Cargill Inc Pano de polímero de lactideo estável em fusao e processo para a sua fabricaçao
US5338822A (en) * 1992-10-02 1994-08-16 Cargill, Incorporated Melt-stable lactide polymer composition and process for manufacture thereof
US6005068A (en) * 1992-10-02 1999-12-21 Cargill Incorporated Melt-stable amorphous lactide polymer film and process for manufacture thereof
NZ256978A (en) * 1992-10-02 1996-05-28 Cargill Inc Paper product coated with a poly(lactide) composition comprising no more than 5 wt % lactide monomer, the poly(lactide) having a number average mw of 10,000 to 200,000
TW333456B (en) 1992-12-07 1998-06-11 Takeda Pharm Ind Co Ltd A pharmaceutical composition of sustained-release preparation the invention relates to a pharmaceutical composition of sustained-release preparation which comprises a physiologically active peptide.
US5594091A (en) * 1994-02-21 1997-01-14 Takeda Chemical Industries, Ltd. Matrix for sustained-release preparation
DE4406172C2 (de) * 1994-02-25 2003-10-02 Sanol Arznei Schwarz Gmbh Polyester
ES2078190B1 (es) * 1994-05-20 1996-08-01 Cusi Lab Procedimiento para el recubrimiento de goticulas o particulas de tamaño nanometrico.
US5817728A (en) * 1995-03-16 1998-10-06 Mitsui Chemicals, Inc. Preparation of degradable copolymers
US5914381A (en) * 1996-09-12 1999-06-22 Mitsui Chemicals, Inc. Degradable polymer and preparation process of the same
US5916883A (en) * 1996-11-01 1999-06-29 Poly-Med, Inc. Acylated cyclodextrin derivatives
AR020650A1 (es) * 1998-08-10 2002-05-22 Poly Med Inc Polimeros fosforilados y conjugados de los mismos
DE19839515B4 (de) * 1998-08-29 2012-02-02 Nanohale Gmbh Neue pharmazeutische Zubereitung, enthaltend kolloidale Polymer-Wirkstoff-Assoziate, insbesondere auch für mucosale Wirkstoffverabreichung
JP2002528602A (ja) 1998-11-02 2002-09-03 ソシエテ・ドゥ・コンセイユ・ドゥ・ルシェルシュ・エ・ダプリカーション・シャンティフィック・エス・ア・エス ラクトンを保有する吸収性ポリマー
US6451346B1 (en) * 1998-12-23 2002-09-17 Amgen Inc Biodegradable pH/thermosensitive hydrogels for sustained delivery of biologically active agents
US8614291B2 (en) 1999-08-10 2013-12-24 Poly-Med, Inc. Phosphorylated polymers and conjugates thereof
US6461631B1 (en) * 1999-11-16 2002-10-08 Atrix Laboratories, Inc. Biodegradable polymer composition
ES2345182T3 (es) * 2000-03-08 2010-09-17 Nanohale Gmbh Vehiculos nanoparticulados coloidales que contienen polimeros en peine solubles en agua cargados o sin cargar y su uso para administracion mucosa.
US6616944B2 (en) * 2000-03-08 2003-09-09 Medinnova Gesellschaft Fur Medizinsche Innovationen Aus Adkademischer Forschung Mbh Self-assembling colloidal carriers for protein delivery
EP1310517B2 (fr) † 2000-08-07 2010-11-17 Wako Pure Chemical Industries, Ltd. Polymere d'acide lactique et son procede de preparation
DE10055742B4 (de) * 2000-11-10 2006-05-11 Schwarz Pharma Ag Neue Polyester, Verfahren zu ihrer Herstellung und aus den Polyestern hergestellte Depot-Arzneiformen
DE10111767B4 (de) * 2001-03-12 2005-03-24 Schwarz Pharma Ag Verfahren zur Herstellung von Polyestern aus Hydroxycarbonsäuren und Polyolen durch Polykondensation
AR034641A1 (es) † 2001-06-29 2004-03-03 Takeda Pharmaceutical Composicion de liberacion controlada y metodo para producirla
GB0122318D0 (en) * 2001-09-14 2001-11-07 Novartis Ag Organic compounds
ES2436439T3 (es) 2001-10-30 2014-01-02 Novartis Ag Formulaciones de medicamento de liberación lenta de iloperidona con un polímero
EP2316468A1 (fr) 2002-02-22 2011-05-04 Shire LLC Système de distribution et méthodes de protection et d'administration de dextroamphetamine
GB0216416D0 (en) 2002-07-15 2002-08-21 Novartis Ag Organic compounds
US20040097419A1 (en) 2002-11-19 2004-05-20 Holger Petersen Organic compounds
US20060089384A1 (en) * 2004-10-25 2006-04-27 Minno George E Ophthalmic compositions and methods of using the same
CN101087607B (zh) * 2004-10-25 2010-07-28 博士伦公司 眼用组合物及使用其的方法
GB2422839B (en) 2005-01-11 2009-06-24 Schlumberger Holdings Degradable polymers for wellbore fluids and processes
US7794495B2 (en) * 2006-07-17 2010-09-14 Advanced Cardiovascular Systems, Inc. Controlled degradation of stents
WO2008029527A1 (fr) * 2006-09-04 2008-03-13 Bio-Energy Corporation Polyol de polyester
CN100460441C (zh) * 2006-09-25 2009-02-11 南开大学 生物可降解星型结构聚乙丙交酯载药微球及其制备方法
NO347209B1 (no) 2006-12-18 2023-07-03 Takeda Pharmaceutical Sammensetning med forlenget frigjøring og fremgangsmåte for å produsere det samme
AR066677A1 (es) 2007-05-24 2009-09-02 Novartis Ag Formulacion de pasireotida. composicion farmaceutica para liberacion prolongada. microparticulas.
RU2490009C2 (ru) 2008-02-22 2013-08-20 Торэй Индастриз, Инк. Микрочастица и ее фармацевтическая композиция
EP2213307A1 (fr) 2009-02-03 2010-08-04 Novartis AG Formulations de dépôt injectables
EP2172189A1 (fr) 2008-10-01 2010-04-07 Novartis AG Compositions pharmaceutiques
US20100086596A1 (en) * 2008-10-06 2010-04-08 Oakwood Laboratories LLC Microspheres for releasing an octreotide compound without an initial time lag
US20100086597A1 (en) * 2008-10-06 2010-04-08 Oakwood Laboratories LLC Microspheres for the sustained release of octreotide with a low initial burst
US9290613B2 (en) 2009-01-16 2016-03-22 Biobase Corporation Polylactic acid resin composition and additive for polylactic acid resin
JP5362400B2 (ja) * 2009-03-17 2013-12-11 株式会社クレハ 低溶融粘度化ポリグリコール酸の製造方法
EP2560676B8 (fr) 2010-04-22 2016-10-12 Intra-Cellular Therapies, Inc. Composés organiques
GB201016433D0 (en) 2010-09-30 2010-11-17 Q Chip Ltd Apparatus and method for making solid beads
GB201016436D0 (en) 2010-09-30 2010-11-17 Q Chip Ltd Method of making solid beads
EP2455415A1 (fr) * 2010-11-17 2012-05-23 Evonik Röhm GmbH Procédé de fabrication de polyesters sous-moléculaires et résorbables, polyesters sous-moléculaires et résorbables fabriqués selon le procédé et leur utilisation
EP2455414A1 (fr) * 2010-11-17 2012-05-23 Evonik Röhm GmbH Procédé pour la production des polyésters resorbables
US20120156304A1 (en) * 2010-12-15 2012-06-21 Thomas Tice Branched polyol polyesters, blends, and pharmaceutical formulations comprising same
WO2013155504A1 (fr) 2012-04-14 2013-10-17 Intra-Cellular Therapies, Inc. Nouveaux procédés
JP2014095067A (ja) * 2012-10-11 2014-05-22 Ricoh Co Ltd 高分子化合物、包接化合物、シート、および、水分散体
HUE053159T2 (hu) 2013-03-15 2021-06-28 Intra Cellular Therapies Inc Szerves vegyületek
TW201605488A (zh) * 2013-10-15 2016-02-16 大塚製藥股份有限公司 用以預防及／或治療多囊腎病之藥物
IL305990B2 (en) 2013-12-03 2025-12-01 Intra Cellular Therapies Inc Long-acting injectable composition comprising polymeric microspheres of heterocycle fused gamma-carboline compounds or a pharmaceutical composition for sustained or delayed release comprising the compounds and their use in the treatment of bipolar disorder i and/or bipolar ii disorder
MX365969B (es) 2014-04-04 2019-06-21 Intra Cellular Therapies Inc Gamma-carbolinas fusionadas con heterociclos sustituidas con deuterio.
RU2016143091A (ru) 2014-04-04 2018-05-08 Интра-Селлулар Терапиз, Инк. Органические соединения
WO2015191554A1 (fr) 2014-06-09 2015-12-17 Intra-Cellular Therapies, Inc. Composés et leurs procédés d'utilisation pour traiter la schizophrénie
JP2016186055A (ja) * 2015-03-27 2016-10-27 株式会社クレハ ポリグリコール酸組成物および一時目止め材
CN108883111B (zh) 2016-01-26 2021-10-08 细胞内治疗公司 有机化合物
PL3407889T3 (pl) 2016-03-25 2021-11-22 Intra-Cellular Therapies, Inc. Związki organiczne i ich zastosowanie w leczeniu lub zapobieganiu zaburzeniom ośrodkowego układu nerwowego
EP3436083A4 (fr) 2016-03-28 2019-11-27 Intra-Cellular Therapies, Inc. Nouvelles compositions et méthodes
US11331316B2 (en) 2016-10-12 2022-05-17 Intra-Cellular Therapies, Inc. Amorphous solid dispersions
US10906906B2 (en) 2016-12-29 2021-02-02 Intra-Cellular Therapies, Inc. Organic compounds
US10961245B2 (en) 2016-12-29 2021-03-30 Intra-Cellular Therapies, Inc. Substituted heterocycle fused gamma-carbolines for treatment of central nervous system disorders
IL268970B2 (en) 2017-03-24 2023-12-01 Intra Cellular Therapies Inc Oral transmucosal formulations of substituted heterocycle fused gamma carbolines
CN111164122B (zh) 2017-07-07 2022-01-04 斯蒂潘公司 用于聚氨酯应用的低粘度多元醇
JP7224333B2 (ja) 2017-07-26 2023-02-17 イントラ－セルラー・セラピーズ・インコーポレイテッド 有機化合物
JP7223742B2 (ja) 2017-07-26 2023-02-16 イントラ－セルラー・セラピーズ・インコーポレイテッド 有機化合物
WO2019104214A1 (fr) 2017-11-22 2019-05-31 Dauntless 2, Inc. Dispositif d'émulsification de membrane pour la création de microsphères
WO2019104225A1 (fr) 2017-11-22 2019-05-31 Dauntless 2, Inc. Formulations de composé thérapeutique
WO2019178484A1 (fr) 2018-03-16 2019-09-19 Intra-Cellular Therapies, Inc. Nouveaux procédés
WO2019183546A1 (fr) 2018-03-23 2019-09-26 Intra-Cellular Therapies, Inc. Composés organiques
AU2019240226B2 (en) 2018-03-23 2024-11-28 Intra-Cellular Therapies, Inc. Organic compounds
WO2019237037A1 (fr) 2018-06-08 2019-12-12 Intra-Cellular Therapies, Inc. Nouvelles méthodes
WO2020005842A1 (fr) 2018-06-25 2020-01-02 Dauntless 2, Inc. Dispositif d'émulsification membranaire avec impulseur pour la création de microsphères
EP3843729A4 (fr) 2018-08-29 2022-06-01 Intra-Cellular Therapies, Inc. Nouvelles compositions et méthodes
CA3108558A1 (fr) 2018-08-31 2020-03-05 Intra-Cellular Therapies, Inc. Nouvelles methodes
CN112584837A (zh) 2018-08-31 2021-03-30 细胞内治疗公司 新方法
BR112021011792A2 (pt) 2018-12-17 2021-08-31 Intra-Cellular Therapies, Inc. Composto orgânico
JP7673040B2 (ja) 2019-07-07 2025-05-08 イントラ－セルラー・セラピーズ・インコーポレイテッド 新規方法
EP4072554A4 (fr) 2019-12-11 2023-12-20 Intra-Cellular Therapies, Inc. Composé organique
US12414948B2 (en) 2022-05-18 2025-09-16 Intra-Cellular Therapies, Inc. Methods
JP2026502895A (ja) 2022-12-30 2026-01-27 イントラ－セルラー・セラピーズ・インコーポレイテッド セロトニン５－ｈｔ２ａ受容体に作用する複素環縮合ガンマ－カルボリン
WO2026011166A1 (fr) 2024-07-03 2026-01-08 Intra-Cellular Therapies, Inc. Hétérocycles substitués destinés à être utilisés dans le traitement de maladies impliquant le récepteur 5-ht2a
WO2026011136A1 (fr) 2024-07-03 2026-01-08 Intra-Cellular Therapies, Inc. Composés organiques

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1020324B (de) * 1954-12-17 1957-12-05 Boehringer Sohn Ingelheim Verfahren zur Herstellung von esterartigen Milchsaeurederivaten mit definierter Kettenlaenge und endstaendiger Ester-, Amid- oder Nitrilgruppe
FR1584732A (fr) * 1968-03-13 1970-01-02
FR1590574A (fr) * 1968-05-09 1970-04-20
US3887699A (en) * 1969-03-24 1975-06-03 Seymour Yolles Biodegradable polymeric article for dispensing drugs
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
IE35855B1 (en) * 1970-12-18 1976-06-09 Ethicon Inc Absorbable copolymer suture
US3963699A (en) * 1974-01-10 1976-06-15 The Procter & Gamble Company Synthesis of higher polyol fatty acid polyesters
NO142306C (no) * 1975-04-18 1980-07-30 Tate & Lyle Ltd Fremgangsmaate til rensing av et fast stoff i form av et omestringsprodukt frembrakt ved reaksjon mellom sukrose og minst ett fettsyretriglycerid
US4328204A (en) * 1977-03-02 1982-05-04 Ethicon, Inc. Absorbable polymer-drug compounds and method for making same
DE2856901D2 (de) * 1977-06-07 1980-11-13 Garching Instrumente Form of implant medicament and preparation process
US4130639A (en) * 1977-09-28 1978-12-19 Ethicon, Inc. Absorbable pharmaceutical compositions based on isomorphic copolyoxalates
US4165432A (en) * 1977-10-18 1979-08-21 Olin Corporation Peroxy di-ester polyols
DE2824112A1 (de) * 1978-06-01 1979-12-06 Garching Instrumente Mikropellets, verfahren zu ihrer herstellung und deren verwendung
US4273920A (en) * 1979-09-12 1981-06-16 Eli Lilly And Company Polymerization process and product
US4334061A (en) * 1979-10-29 1982-06-08 Ethyl Corporation Process for recovery of polyol fatty acid polyesters
DE3045135A1 (de) * 1980-11-29 1982-06-09 Sandoz-Patent-GmbH, 7850 Lörrach Pharmazeutische kompositionen enthaltende bioabbaubare polymere
IE52535B1 (en) * 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
ATE37983T1 (de) * 1982-04-22 1988-11-15 Ici Plc Mittel mit verzoegerter freigabe.
US4452973A (en) * 1982-11-12 1984-06-05 American Cyanamid Company Poly(glycolic acid)/poly(oxyethylene) triblock copolymers and method of manufacturing the same
FR2537980B1 (fr) * 1982-12-17 1986-12-19 Sandoz Sa Derives d'acides hydroxycarboxyliques oligomeres, leur preparation et leur utilisation

Also Published As

Publication number Publication date
LU85514A1 (fr) 1985-04-24
NZ209335A (en) 1988-08-30
DE3430852C2 (de) 2003-08-14
IE842171L (en) 1985-02-26
JPS6076531A (ja) 1985-05-01
DK173556B1 (da) 2001-03-12
FR2551072B1 (fr) 1988-01-15
GB2145422A (en) 1985-03-27
AT395584B (de) 1993-01-25
US5922682A (en) 1999-07-13
GB2145422B (en) 1987-08-26
HK67390A (en) 1990-09-07
DK407284D0 (da) 1984-08-24
CY1556A (en) 1991-03-22
PT79129B (en) 1986-07-17
IL72763A (en) 1988-02-29
GB8421273D0 (en) 1984-09-26
SE8404225L (sv) 1985-02-27
ZA846634B (en) 1986-04-30
IT1176629B (it) 1987-08-18
ES535399A0 (es) 1987-06-16
SE462098B (sv) 1990-05-07
IE58818B1 (en) 1993-11-17
DK407284A (da) 1985-02-27
JPH0819226B2 (ja) 1996-02-28
PT79129A (en) 1984-09-01
AU3234884A (en) 1985-02-28
HUT38265A (en) 1986-05-28
US5922338A (en) 1999-07-13
MY101861A (en) 1992-01-31
BE900406A (fr) 1985-02-22
NL190415B (nl) 1993-09-16
ES8706750A1 (es) 1987-06-16
GR80184B (en) 1985-01-02
DE3430852A1 (de) 1985-03-14
NL960014I1 (nl) 1996-10-01
NL190415C (nl) 1994-02-16
IT8422413A0 (it) 1984-08-24
AU575066B2 (en) 1988-07-21
ATA271384A (de) 1992-06-15
PH23556A (en) 1989-08-25
SE8404225D0 (sv) 1984-08-24
FR2551072A1 (fr) 1985-03-01
IL72763A0 (en) 1984-11-30
HU195426B (en) 1988-05-30
NL8402547A (nl) 1985-03-18
CH656884A5 (de) 1986-07-31

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