IL78536A0 - 1,12b-disubstituted octahydroindolo(2,3-a)quinolizine derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

1,12b-disubstituted octahydroindolo(2,3-a)quinolizine derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL78536A0
IL78536A0 IL78536A IL7853686A IL78536A0 IL 78536 A0 IL78536 A0 IL 78536A0 IL 78536 A IL78536 A IL 78536A IL 7853686 A IL7853686 A IL 7853686A IL 78536 A0 IL78536 A0 IL 78536A0
Authority
IL
Israel
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
quinolizine derivatives
octahydroindolo
Prior art date
Application number
IL78536A
Other languages
English (en)
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of IL78536A0 publication Critical patent/IL78536A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
IL78536A 1985-04-19 1986-04-18 1,12b-disubstituted octahydroindolo(2,3-a)quinolizine derivatives,their preparation and pharmaceutical compositions containing them IL78536A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU851517A HU194220B (en) 1985-04-19 1985-04-19 Process for production of derivatives of 1,12 b disubstituated-octahydro-indolo /2,3-a/ quinolisine and medical compounds containing thereof

Publications (1)

Publication Number Publication Date
IL78536A0 true IL78536A0 (en) 1986-08-31

Family

ID=10954837

Family Applications (1)

Application Number Title Priority Date Filing Date
IL78536A IL78536A0 (en) 1985-04-19 1986-04-18 1,12b-disubstituted octahydroindolo(2,3-a)quinolizine derivatives,their preparation and pharmaceutical compositions containing them

Country Status (10)

Country Link
US (1) US4843080A (fr)
EP (1) EP0202774A3 (fr)
JP (1) JPS61249985A (fr)
AU (1) AU587025B2 (fr)
CA (1) CA1301171C (fr)
DK (1) DK179986A (fr)
FI (1) FI861642A7 (fr)
HU (1) HU194220B (fr)
IL (1) IL78536A0 (fr)
ZA (1) ZA862942B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU194221B (en) * 1985-04-19 1988-01-28 Richter Gedeon Vegyeszet Process for preparing novel octahydro-indolo/2,3-a/quinoline derivative and pharmaceutical comprising this compound
HU195214B (en) * 1985-04-19 1988-04-28 Richter Gedeon Vegyeszet Process for producing 12b-substituted-1-(hydroxymethyl)-octahydro-indolo /2,3-a/ quinolizine derivatives and pharmaceutical preparations comprising these compounds
EP0401929A3 (fr) * 1989-06-08 1991-10-23 Duphar International Research B.V Méthode de préparation de N-oxotétrahydro- -carbolines
PT2956440T (pt) 2013-02-08 2018-05-08 Gen Mills Inc Produtos alimentares com baixo teor de sódio
WO2020021489A2 (fr) 2018-07-27 2020-01-30 University Of Sharjah Découverte de nouveaux composés de première classe inspirés de la nature ciblant la fonction mitochondriale et composition pharmaceutique associée

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3478051A (en) * 1967-03-17 1969-11-11 Sandoz Ag Azecino- and azonino(5,4-b)indoles
HU174502B (hu) * 1976-12-30 1980-01-28 Richter Gedeon Vegyeszet Sposob poluchenija novykh proizvodnykh oktagidro-indolo/2,3-a/-khinolizina
GB2009749B (en) * 1977-11-25 1982-04-28 Scras Indolo(1,3-a)quinolizidines
ZA786426B (en) * 1977-11-25 1979-10-31 Scras New indulo(2,3-a)quinolizidines,preparation and therapeutic use
HU178700B (en) * 1978-02-10 1982-06-28 Richter Gedeon Vegyeszet Process for preparing 1,1-disubstituted octahydro-indolo/2,3-a/-quinolizines
HU178402B (en) * 1978-08-01 1982-04-28 Richter Gedeon Vegyeszet New process for producing okrahydro-indolo-square bracket-2,3-a-square bracket closed-quinolysines
HU177732B (en) * 1978-12-15 1981-12-28 Richter Gedeon Vegyeszet Process for producing 10-bromo-vincamine and acid additional salts thereof,and 10-bromo-14-epivincamine
US4353911A (en) * 1979-07-20 1982-10-12 Andre Buzas Indolo(2,3-a)quinolizidines, useful in increasing femoral and vertebral blood flow
US4358452A (en) * 1980-05-09 1982-11-09 John Wyeth & Brother Limited N-[1,2,3,4,6,7,12,12 α-octahydro-2H-indolo(2,3α)-quinolizinyl-2β-yl]alkane and benzyl sulfonamides and anti-hypertensive use thereof
HU185305B (en) * 1981-08-23 1985-01-28 Richter Gedeon Vegyeszet Process for preparing vincine and apovincine
HU182380B (en) * 1981-09-30 1983-12-28 Richter Gedeon Vegyeszet Process for producing esters of vincaminic acid
ATE25383T1 (de) * 1981-11-18 1987-02-15 Thal Claude Indoloquinolizinderivate, verfahren zu ihrer herstellung und ihre therapeutische anwendung.
HU194221B (en) * 1985-04-19 1988-01-28 Richter Gedeon Vegyeszet Process for preparing novel octahydro-indolo/2,3-a/quinoline derivative and pharmaceutical comprising this compound
HU195214B (en) * 1985-04-19 1988-04-28 Richter Gedeon Vegyeszet Process for producing 12b-substituted-1-(hydroxymethyl)-octahydro-indolo /2,3-a/ quinolizine derivatives and pharmaceutical preparations comprising these compounds

Also Published As

Publication number Publication date
ZA862942B (en) 1987-03-25
AU5638186A (en) 1986-10-23
CA1301171C (fr) 1992-05-19
DK179986D0 (da) 1986-04-18
FI861642A7 (fi) 1986-10-20
JPS61249985A (ja) 1986-11-07
HU194220B (en) 1988-01-28
US4843080A (en) 1989-06-27
FI861642A0 (fi) 1986-04-18
DK179986A (da) 1986-10-20
EP0202774A3 (fr) 1989-03-15
AU587025B2 (en) 1989-08-03
EP0202774A2 (fr) 1986-11-26
HUT40650A (en) 1987-01-28

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Legal Events

Date Code Title Description
RH Patent void