IL90572A0 - Cholestadiene derivatives,process for their preparation and pharmaceutical composition to inhibit hmg-coa reductase - Google Patents

Cholestadiene derivatives,process for their preparation and pharmaceutical composition to inhibit hmg-coa reductase

Info

Publication number
IL90572A0
IL90572A0 IL90572A IL9057289A IL90572A0 IL 90572 A0 IL90572 A0 IL 90572A0 IL 90572 A IL90572 A IL 90572A IL 9057289 A IL9057289 A IL 9057289A IL 90572 A0 IL90572 A0 IL 90572A0
Authority
IL
Israel
Prior art keywords
cholestadiene
derivatives
preparation
pharmaceutical composition
coa reductase
Prior art date
Application number
IL90572A
Other languages
English (en)
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IL90572A0 publication Critical patent/IL90572A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL90572A 1988-06-14 1989-06-12 Cholestadiene derivatives,process for their preparation and pharmaceutical composition to inhibit hmg-coa reductase IL90572A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3820177A DE3820177A1 (de) 1988-06-14 1988-06-14 Cholestadienderivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel mit hmg-coa-reduktase-hemmender wirkung

Publications (1)

Publication Number Publication Date
IL90572A0 true IL90572A0 (en) 1990-01-18

Family

ID=6356493

Family Applications (1)

Application Number Title Priority Date Filing Date
IL90572A IL90572A0 (en) 1988-06-14 1989-06-12 Cholestadiene derivatives,process for their preparation and pharmaceutical composition to inhibit hmg-coa reductase

Country Status (11)

Country Link
EP (1) EP0346759A3 (da)
JP (1) JPH0236192A (da)
KR (1) KR910000786A (da)
AU (1) AU3629189A (da)
DE (1) DE3820177A1 (da)
DK (1) DK288989A (da)
FI (1) FI892867L (da)
IL (1) IL90572A0 (da)
NO (1) NO892441L (da)
PT (1) PT90843A (da)
ZA (1) ZA894469B (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200066690A (ko) 2017-10-16 2020-06-10 칭화대학교 메발로네이트 경로 억제제 및 이의 약제학적 조성물

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4107188A (en) * 1977-04-22 1978-08-15 Hoffmann-La Roche Inc. Pregnanes

Also Published As

Publication number Publication date
DE3820177A1 (de) 1989-12-21
NO892441L (no) 1989-12-15
EP0346759A3 (de) 1990-01-31
FI892867A7 (fi) 1989-12-15
JPH0236192A (ja) 1990-02-06
AU3629189A (en) 1989-12-21
DK288989D0 (da) 1989-06-13
KR910000786A (ko) 1991-01-30
DK288989A (da) 1989-12-15
ZA894469B (en) 1990-02-28
EP0346759A2 (de) 1989-12-20
FI892867A0 (fi) 1989-06-12
PT90843A (pt) 1989-12-29
FI892867L (fi) 1989-12-15
NO892441D0 (no) 1989-06-13

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